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The map label for this gene is actR [H]

Identifier: 182682576

GI number: 182682576

Start: 2316389

End: 2316967

Strand: Direct

Name: actR [H]

Synonym: XfasM23_2064

Alternate gene names: 182682576

Gene position: 2316389-2316967 (Clockwise)

Preceding gene: 182682575

Following gene: 182682579

Centisome position: 91.35

GC content: 57.17

Gene sequence:

>579_bases
ATGAATCACTCCGCCGCCAAGATCGGCTTGCTAGTCGACGACGACACACTCTATCTGCGCACCCTACAGCGCAGTTTGGG
ACGCCGTGGCGTAGACACCGTGACCGCCACCGATGCAGTCAGCGCATTAACCGCTGCGCGTAGCGCGCTCCCAAGTTTCG
CCTTGCTCGACCTAAAGCTCGGCCAAGACTCAGGGTTAGCGCTCATCCAAGAACTGCGCGCCATCCGCAGCGATATGCGA
ATCCTGCTCGTCACCGGCTACGCCAGCATTGCCACTGCGGTAGAAGCCATTAAACGCGGTGCCGACGAATATCTACCCAA
ACCAGCCAACATCAACACCATTCTGCGTGCAATCAGCGAAGACACAGCAAACAGATTAACGCCGGACAAGGACGAATCTG
CTTTACATACGATGACTCCGCTCAGTCGCCTTCAGTGGGAACATATCCAGCAAGCATTACACGAGACGGACGGCAACATC
TCCGCCGCCGCACGGTTACTTGGCATGCATCGGCGCTCTCTGCAGCGCAAGCTAACCAAGCGCCCCAGCCCTGGAACGCT
GCACGATTCAGATCATTAA

Upstream 100 bases:

>100_bases
CGACCGTCGAACGTCTGCAAGGCGACATCTGGATGCAACCCGCCAAAGGACGCGGCACACGAGTAAGCTTTCGAGTGCCC
TTGAAGGAAACATCCACGGC

Downstream 100 bases:

>100_bases
AGCGTGATAGCCCAAAACGCTATATAGAGCGTTCAATGAGACATCGCCGCTTCCCAACCAGGACACTACTGCACATGAAT
ACCACAGCCCTGGGAGTCCT

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MNHSAAKIGLLVDDDTLYLRTLQRSLGRRGVDTVTATDAVSALTAARSALPSFALLDLKLGQDSGLALIQELRAIRSDMR
ILLVTGYASIATAVEAIKRGADEYLPKPANINTILRAISEDTANRLTPDKDESALHTMTPLSRLQWEHIQQALHETDGNI
SAAARLLGMHRRSLQRKLTKRPSPGTLHDSDH

Sequences:

>Translated_192_residues
MNHSAAKIGLLVDDDTLYLRTLQRSLGRRGVDTVTATDAVSALTAARSALPSFALLDLKLGQDSGLALIQELRAIRSDMR
ILLVTGYASIATAVEAIKRGADEYLPKPANINTILRAISEDTANRLTPDKDESALHTMTPLSRLQWEHIQQALHETDGNI
SAAARLLGMHRRSLQRKLTKRPSPGTLHDSDH
>Mature_192_residues
MNHSAAKIGLLVDDDTLYLRTLQRSLGRRGVDTVTATDAVSALTAARSALPSFALLDLKLGQDSGLALIQELRAIRSDMR
ILLVTGYASIATAVEAIKRGADEYLPKPANINTILRAISEDTANRLTPDKDESALHTMTPLSRLQWEHIQQALHETDGNI
SAAARLLGMHRRSLQRKLTKRPSPGTLHDSDH

Specific function: Member of the two-component regulatory system ActS/ActR acting in acid tolerance. These data implicate that a two- component sensor may be involved in pH sensing and/or response [H]

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1788550, Length=140, Percent_Identity=29.2857142857143, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=31.0344827586207, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20977; Mature: 20977

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHSAAKIGLLVDDDTLYLRTLQRSLGRRGVDTVTATDAVSALTAARSALPSFALLDLKL
CCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEEEE
GQDSGLALIQELRAIRSDMRILLVTGYASIATAVEAIKRGADEYLPKPANINTILRAISE
CCCCCHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHH
DTANRLTPDKDESALHTMTPLSRLQWEHIQQALHETDGNISAAARLLGMHRRSLQRKLTK
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
RPSPGTLHDSDH
CCCCCCCCCCCC
>Mature Secondary Structure
MNHSAAKIGLLVDDDTLYLRTLQRSLGRRGVDTVTATDAVSALTAARSALPSFALLDLKL
CCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEEEE
GQDSGLALIQELRAIRSDMRILLVTGYASIATAVEAIKRGADEYLPKPANINTILRAISE
CCCCCHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHH
DTANRLTPDKDESALHTMTPLSRLQWEHIQQALHETDGNISAAARLLGMHRRSLQRKLTK
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
RPSPGTLHDSDH
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]