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The map label for this gene is pdxA

Identifier: 182682447

GI number: 182682447

Start: 2162529

End: 2163521

Strand: Reverse

Name: pdxA

Synonym: XfasM23_1934

Alternate gene names: 182682447

Gene position: 2163521-2162529 (Counterclockwise)

Preceding gene: 182682448

Following gene: 182682444

Centisome position: 85.32

GC content: 58.51

Gene sequence:

>993_bases
ATGTTGCACCCCGCGCTTGCTTTGGTTCCTGGCGAACCGGCGGGCGTTGGCCCTGAATTGTGCGTGCGGTTGGTACAACA
GCCGCGTCAAGATTGCCGACTTGTTGCCTTCGCCGATCCAGCCACCTTACAGGCTGCTGCCGCTGCACTAGATTTGCCGC
TGCGTTTGCTTCCGCCCGAAGCACTCCCTGAGCGTCCTGGTGATCTGCCTATACAGGCCCATTGCCACGTTCATCCGACG
CGTTTTGGTCACCCAGACCCTGCCAATGCTCCTGCGGTGATCGCTGCACTCTGTGAGGCGGCAAGCCACTGCGTACATGG
AGTGCTGCATGGCATCGTCACTGGCCCGGTACACAAGGCCGTTATCAATCAGAGCGGCATCCATTACACCGGCACGACAG
AATTGCTGGCCGCGCAGGCAGAGTGCGACGTAGTCATGATGTTGGCTAATCCGCATCTGCGCGTGGCCCTGGTCACCACC
CATCTGCCGTTGCGTGATGTGCCGGACGCTATCACTGCAGCACTGTTAGAGCGGTGCTTACGGATTGTTAATACCGCGAT
GTGCGGTGACTTTGGCATCGCAACCCCTCGCATTGCCGTCCTTGGATTAAATCCGCATGCAGGTGAAGAGGGTTATCTTG
GTCGCGAAGAACTGGATGTTGTCATCCCCGTGTTGCAGCGTTTGCGTGCCGAAGGCATGGTTTTGCTGGGGCCACTGTCT
GCGGATACGGCGTTCTTGCCAACCAAGTTGATTGGCTATGATGCAGTGGTGGCGATGTATCACGACCAAGGGTTGCCAGT
ACTCAAACACAGCGGATTTGAACAGGCGGTCAATATCACCTTGGGCCTTCCCTATCCGCGTGTCGCTGTGGACCACGGCA
CCGCCCTTGACCTTGCTGGCCGTGGCGTTGCTGATCCTTCTAGTCTCTTTGCAGCCACTGCGCTATGTGCCCGGCTAGCT
GCGTCGCGCGCCTTGCTGTCCGTACGTTCCTGA

Upstream 100 bases:

>100_bases
TCTTCAGATTGAGGAGCCAGCTGACGATCACCATACTCCCAGTGCGGCGGTGACCCCGGCAACAGGGGCCGTATTACCGG
CCGCAACGAAGCACTGATTT

Downstream 100 bases:

>100_bases
TGACCGCGCCTCAGTGATTCCAAACGAGCGCCTTGTATCGGGCAGCTACCGTGTTTCCCTGTGATACAACCTCATCAACC
GGCTGACAGCAGTAGCGTGA

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MLHPALALVPGEPAGVGPELCVRLVQQPRQDCRLVAFADPATLQAAAAALDLPLRLLPPEALPERPGDLPIQAHCHVHPT
RFGHPDPANAPAVIAALCEAASHCVHGVLHGIVTGPVHKAVINQSGIHYTGTTELLAAQAECDVVMMLANPHLRVALVTT
HLPLRDVPDAITAALLERCLRIVNTAMCGDFGIATPRIAVLGLNPHAGEEGYLGREELDVVIPVLQRLRAEGMVLLGPLS
ADTAFLPTKLIGYDAVVAMYHDQGLPVLKHSGFEQAVNITLGLPYPRVAVDHGTALDLAGRGVADPSSLFAATALCARLA
ASRALLSVRS

Sequences:

>Translated_330_residues
MLHPALALVPGEPAGVGPELCVRLVQQPRQDCRLVAFADPATLQAAAAALDLPLRLLPPEALPERPGDLPIQAHCHVHPT
RFGHPDPANAPAVIAALCEAASHCVHGVLHGIVTGPVHKAVINQSGIHYTGTTELLAAQAECDVVMMLANPHLRVALVTT
HLPLRDVPDAITAALLERCLRIVNTAMCGDFGIATPRIAVLGLNPHAGEEGYLGREELDVVIPVLQRLRAEGMVLLGPLS
ADTAFLPTKLIGYDAVVAMYHDQGLPVLKHSGFEQAVNITLGLPYPRVAVDHGTALDLAGRGVADPSSLFAATALCARLA
ASRALLSVRS
>Mature_330_residues
MLHPALALVPGEPAGVGPELCVRLVQQPRQDCRLVAFADPATLQAAAAALDLPLRLLPPEALPERPGDLPIQAHCHVHPT
RFGHPDPANAPAVIAALCEAASHCVHGVLHGIVTGPVHKAVINQSGIHYTGTTELLAAQAECDVVMMLANPHLRVALVTT
HLPLRDVPDAITAALLERCLRIVNTAMCGDFGIATPRIAVLGLNPHAGEEGYLGREELDVVIPVLQRLRAEGMVLLGPLS
ADTAFLPTKLIGYDAVVAMYHDQGLPVLKHSGFEQAVNITLGLPYPRVAVDHGTALDLAGRGVADPSSLFAATALCARLA
ASRALLSVRS

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=319, Percent_Identity=50.7836990595611, Blast_Score=282, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 34655; Mature: 34655

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHPALALVPGEPAGVGPELCVRLVQQPRQDCRLVAFADPATLQAAAAALDLPLRLLPPE
CCCCCEEEECCCCCCCCHHHHHHHHHCCHHHCEEEEEECCHHHHHHHHHHCCCCEECCCH
ALPERPGDLPIQAHCHVHPTRFGHPDPANAPAVIAALCEAASHCVHGVLHGIVTGPVHKA
HCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VINQSGIHYTGTTELLAAQAECDVVMMLANPHLRVALVTTHLPLRDVPDAITAALLERCL
HHCCCCCEECCCHHHHHHHCCCCEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHH
RIVNTAMCGDFGIATPRIAVLGLNPHAGEEGYLGREELDVVIPVLQRLRAEGMVLLGPLS
HHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCC
ADTAFLPTKLIGYDAVVAMYHDQGLPVLKHSGFEQAVNITLGLPYPRVAVDHGTALDLAG
CCCCCCCHHHHHHHEEEEEEECCCCCHHHCCCCCCEEEEEEECCCCCEEECCCCEEEECC
RGVADPSSLFAATALCARLAASRALLSVRS
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLHPALALVPGEPAGVGPELCVRLVQQPRQDCRLVAFADPATLQAAAAALDLPLRLLPPE
CCCCCEEEECCCCCCCCHHHHHHHHHCCHHHCEEEEEECCHHHHHHHHHHCCCCEECCCH
ALPERPGDLPIQAHCHVHPTRFGHPDPANAPAVIAALCEAASHCVHGVLHGIVTGPVHKA
HCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VINQSGIHYTGTTELLAAQAECDVVMMLANPHLRVALVTTHLPLRDVPDAITAALLERCL
HHCCCCCEECCCHHHHHHHCCCCEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHH
RIVNTAMCGDFGIATPRIAVLGLNPHAGEEGYLGREELDVVIPVLQRLRAEGMVLLGPLS
HHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCC
ADTAFLPTKLIGYDAVVAMYHDQGLPVLKHSGFEQAVNITLGLPYPRVAVDHGTALDLAG
CCCCCCCHHHHHHHEEEEEEECCCCCHHHCCCCCCEEEEEEECCCCCEEECCCCEEEECC
RGVADPSSLFAATALCARLAASRALLSVRS
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]