Click here to switch to the map view.

The map label for this gene is alr

Identifier: 182682437

GI number: 182682437

Start: 2143471

End: 2144559

Strand: Reverse

Name: alr

Synonym: XfasM23_1923

Alternate gene names: 182682437

Gene position: 2144559-2143471 (Counterclockwise)

Preceding gene: 182682438

Following gene: 182682436

Centisome position: 84.57

GC content: 54.36

Gene sequence:

>1089_bases
GTGCGTCCCGCCCACGCCGTAATTGATCTGGATGCGTTACGTCACAATTATCGATTTGCTCGCCGTCTTGGCGGTGGCAA
GGCGTTAGCTGTGGTGAAAGCCGATGCGTATGGTCACGGTGCGGTGCGTTGTGCGCAGGCTTTGGAGGCTGAAGTTGATG
GTTTTGCGGTGGCGTGTATCGAAGAGGCGTTGGAGTTACGCCAAGCCGGTATCCAGGCACCGATCCTGTTGCTGGAAGGA
TTTTTCGAGGTTGAAGAGCTGGAATTGATTGCTAAGCACAATTTATGGACTGTGATTGCTTCGTCCTGGCAGGTGCGGGC
GTTGGCTGCGTTCCACAGTCCATCTCCAATTGGGGTGTGGCTTAAGTTGGATAGTGGCATGCATCGGCTTGGTTTGGAGC
CAAAGGAGTTTCGTGATGCTTGGATGTCTCTGCATAGTCTGCCGCAGGTGGGCGAGGTCGTCTTGATGACGCATTTGGCC
CGTGCTGATGAGTTGGATAATCCTCGTACCAATGAGCAGGCATCGGTTTTTGCACATGCTTCGCAGGGAATGGTGGCGCC
AGCAAGTGTGTGTAACTCTTCAGGTTTGCTTGGTTGGGCAGGGTTGTACAGTGATTGGGGTCGGCCCGGGTTAATGTTGT
ACGGTGTCAATCCTATTTCGCAGGAGAGCACGTCACTTAGTGGGCCATTGCGTCCTGTGATGATGGTGTATTCCAAGCTG
ATTGCGGTACGCGAGTTGCCTGCCGGCGAGCCAGTTGGCTATGGGGCATCCTTTGTCACTGAGCGGCCAACCCGGGTTGG
TGTGGTAGCGATGGGCTATGCAGACGGTTACCCGTATTTTGCGGTCAATGGTACGCCGCTCTTGGTTGATGGGCGTGTTT
GTCCGTTGATCGGCCGGGTTTCTATGGACATGTTGACGGTTGATCTGACAGACCATCCGCAGGCGGATGTTGGCAGTCAA
GTGCAATTGTGGGGTGTGCAACCGGGTGTGGCTGAACTTGCGGCACATTGTAATTTGAGCGCTTATCAGTTGTTGTGCGG
TCTTAAGCGTGTACGTCGATACTATTTGGGTGAGATGGGCGCAGTGTGA

Upstream 100 bases:

>100_bases
CCGATTTGATATGTTGTCGCCCTTGTGAAATCTCCAGTGAAGGGTTGGATATGTTCCGTTACTTGGTGTCGACGATACCT
TGCCCGCAAGAGTGTGCTCC

Downstream 100 bases:

>100_bases
GGGCTGGGGTGCTGCTAGTGGAGCAGTTTTGTGTTTTTCTAACGTTCACTACGGTCGTGTTTCTACGGTGTTCAAGCTGT
TTGGCGTCAAATGGGTTATA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MRPAHAVIDLDALRHNYRFARRLGGGKALAVVKADAYGHGAVRCAQALEAEVDGFAVACIEEALELRQAGIQAPILLLEG
FFEVEELELIAKHNLWTVIASSWQVRALAAFHSPSPIGVWLKLDSGMHRLGLEPKEFRDAWMSLHSLPQVGEVVLMTHLA
RADELDNPRTNEQASVFAHASQGMVAPASVCNSSGLLGWAGLYSDWGRPGLMLYGVNPISQESTSLSGPLRPVMMVYSKL
IAVRELPAGEPVGYGASFVTERPTRVGVVAMGYADGYPYFAVNGTPLLVDGRVCPLIGRVSMDMLTVDLTDHPQADVGSQ
VQLWGVQPGVAELAAHCNLSAYQLLCGLKRVRRYYLGEMGAV

Sequences:

>Translated_362_residues
MRPAHAVIDLDALRHNYRFARRLGGGKALAVVKADAYGHGAVRCAQALEAEVDGFAVACIEEALELRQAGIQAPILLLEG
FFEVEELELIAKHNLWTVIASSWQVRALAAFHSPSPIGVWLKLDSGMHRLGLEPKEFRDAWMSLHSLPQVGEVVLMTHLA
RADELDNPRTNEQASVFAHASQGMVAPASVCNSSGLLGWAGLYSDWGRPGLMLYGVNPISQESTSLSGPLRPVMMVYSKL
IAVRELPAGEPVGYGASFVTERPTRVGVVAMGYADGYPYFAVNGTPLLVDGRVCPLIGRVSMDMLTVDLTDHPQADVGSQ
VQLWGVQPGVAELAAHCNLSAYQLLCGLKRVRRYYLGEMGAV
>Mature_362_residues
MRPAHAVIDLDALRHNYRFARRLGGGKALAVVKADAYGHGAVRCAQALEAEVDGFAVACIEEALELRQAGIQAPILLLEG
FFEVEELELIAKHNLWTVIASSWQVRALAAFHSPSPIGVWLKLDSGMHRLGLEPKEFRDAWMSLHSLPQVGEVVLMTHLA
RADELDNPRTNEQASVFAHASQGMVAPASVCNSSGLLGWAGLYSDWGRPGLMLYGVNPISQESTSLSGPLRPVMMVYSKL
IAVRELPAGEPVGYGASFVTERPTRVGVVAMGYADGYPYFAVNGTPLLVDGRVCPLIGRVSMDMLTVDLTDHPQADVGSQ
VQLWGVQPGVAELAAHCNLSAYQLLCGLKRVRRYYLGEMGAV

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=359, Percent_Identity=44.8467966573816, Blast_Score=284, Evalue=5e-78,
Organism=Escherichia coli, GI1787439, Length=348, Percent_Identity=41.9540229885057, Blast_Score=274, Evalue=8e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 39157; Mature: 39157

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAHAVIDLDALRHNYRFARRLGGGKALAVVKADAYGHGAVRCAQALEAEVDGFAVACI
CCCCHHEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHH
EEALELRQAGIQAPILLLEGFFEVEELELIAKHNLWTVIASSWQVRALAAFHSPSPIGVW
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEECCCCCEEEE
LKLDSGMHRLGLEPKEFRDAWMSLHSLPQVGEVVLMTHLARADELDNPRTNEQASVFAHA
EEECCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEC
SQGMVAPASVCNSSGLLGWAGLYSDWGRPGLMLYGVNPISQESTSLSGPLRPVMMVYSKL
CCCCCCHHHHCCCCCCEEEHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
IAVRELPAGEPVGYGASFVTERPTRVGVVAMGYADGYPYFAVNGTPLLVDGRVCPLIGRV
HHHHCCCCCCCCCCCCHHHCCCCCEEEEEEEECCCCCCEEEECCEEEEECCCCCCHHHCC
SMDMLTVDLTDHPQADVGSQVQLWGVQPGVAELAAHCNLSAYQLLCGLKRVRRYYLGEMG
EEEEEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
AV
CC
>Mature Secondary Structure
MRPAHAVIDLDALRHNYRFARRLGGGKALAVVKADAYGHGAVRCAQALEAEVDGFAVACI
CCCCHHEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHH
EEALELRQAGIQAPILLLEGFFEVEELELIAKHNLWTVIASSWQVRALAAFHSPSPIGVW
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEECCCCCEEEE
LKLDSGMHRLGLEPKEFRDAWMSLHSLPQVGEVVLMTHLARADELDNPRTNEQASVFAHA
EEECCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEC
SQGMVAPASVCNSSGLLGWAGLYSDWGRPGLMLYGVNPISQESTSLSGPLRPVMMVYSKL
CCCCCCHHHHCCCCCCEEEHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
IAVRELPAGEPVGYGASFVTERPTRVGVVAMGYADGYPYFAVNGTPLLVDGRVCPLIGRV
HHHHCCCCCCCCCCCCHHHCCCCCEEEEEEEECCCCCCEEEECCEEEEECCCCCCHHHCC
SMDMLTVDLTDHPQADVGSQVQLWGVQPGVAELAAHCNLSAYQLLCGLKRVRRYYLGEMG
EEEEEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
AV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12533478 [H]