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The map label for this gene is metI [H]

Identifier: 182682421

GI number: 182682421

Start: 2123542

End: 2124249

Strand: Direct

Name: metI [H]

Synonym: XfasM23_1907

Alternate gene names: 182682421

Gene position: 2123542-2124249 (Clockwise)

Preceding gene: 182682420

Following gene: 182682422

Centisome position: 83.75

GC content: 56.5

Gene sequence:

>708_bases
ATGAATATCCCCATGATCTTTCCCTCAATCGCCGCTCCCGGTTTTTTCGTCAACCTGGACGCTGATAAGTGGGAAGACAT
CGGTCGCGCCACACTCGATACCCTGCTCATGGTCGGAGGTGCATTGCCACCCGCATTGGCGCTTGGTCTTCCCTTGGGAA
TCGCACTGTATTTATGCAACACATCGCAATTGCGCCGCCATCCCCAGGTGTACACCCTGCTGGCACTGGCAGTGAATCTA
TTACGCTCGGTGCCCTTTATCATTTTGATGATCACAATGATCCCAGTCACCTTGCTGATCATGGGGACCTCACTAGGCAT
CCGTGGTGCAATCCTGCCGCTAGTCATCGGTGCAGCACCGTTCTACGCACGCCTCGTCGAAAGCGCGCTACGCGAGGTTG
ATCGTGGTGTCGTCGAAGCTGCACAAGCGATGGGAGCAACCACCTGGCAACTCGTCTGGCGGGTCCTGCTACCAGAAGCA
CGCCCCGGTTTGATTGCTGGTGCCACAATCACCGCAATCGCGGTGGTCGGCTTTACAGCAATGGGCGGCGCAATCGGCTC
GGGGGGATTGGGTGACGTCGCCTACCGCGAAGGCTATCTGCGCTCACACACAGACGTTGCTCTGGTCACTGTGATTGCAC
TGCTCATGGTGGTGCAATTGATACAGATGTTTGGTGATTGGTTGGTCGCACACTACAGCCGACGTTGA

Upstream 100 bases:

>100_bases
CACCCTACGGACAATTGACTGTCGCGCTGTCTGGCGGCGACCCAGTCGCCGCACAGGCAGCGTTTGCTGCTGCCGGCATC
CATATTGAGGAGCTACGCGC

Downstream 100 bases:

>100_bases
GCTTCAATACACATCACCAAGCAAATGTCGCAGCCATGCTTTGCTACAGTAAAGCGCGCATTTCCAACTATCTTTCATAA
CCGACTCTATGCAATGAAGC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MNIPMIFPSIAAPGFFVNLDADKWEDIGRATLDTLLMVGGALPPALALGLPLGIALYLCNTSQLRRHPQVYTLLALAVNL
LRSVPFIILMITMIPVTLLIMGTSLGIRGAILPLVIGAAPFYARLVESALREVDRGVVEAAQAMGATTWQLVWRVLLPEA
RPGLIAGATITAIAVVGFTAMGGAIGSGGLGDVAYREGYLRSHTDVALVTVIALLMVVQLIQMFGDWLVAHYSRR

Sequences:

>Translated_235_residues
MNIPMIFPSIAAPGFFVNLDADKWEDIGRATLDTLLMVGGALPPALALGLPLGIALYLCNTSQLRRHPQVYTLLALAVNL
LRSVPFIILMITMIPVTLLIMGTSLGIRGAILPLVIGAAPFYARLVESALREVDRGVVEAAQAMGATTWQLVWRVLLPEA
RPGLIAGATITAIAVVGFTAMGGAIGSGGLGDVAYREGYLRSHTDVALVTVIALLMVVQLIQMFGDWLVAHYSRR
>Mature_235_residues
MNIPMIFPSIAAPGFFVNLDADKWEDIGRATLDTLLMVGGALPPALALGLPLGIALYLCNTSQLRRHPQVYTLLALAVNL
LRSVPFIILMITMIPVTLLIMGTSLGIRGAILPLVIGAAPFYARLVESALREVDRGVVEAAQAMGATTWQLVWRVLLPEA
RPGLIAGATITAIAVVGFTAMGGAIGSGGLGDVAYREGYLRSHTDVALVTVIALLMVVQLIQMFGDWLVAHYSRR

Specific function: Part of the ABC transporter complex metNIQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport [H]

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786397, Length=190, Percent_Identity=47.8947368421053, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1788451, Length=222, Percent_Identity=30.1801801801802, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25058; Mature: 25058

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIPMIFPSIAAPGFFVNLDADKWEDIGRATLDTLLMVGGALPPALALGLPLGIALYLCN
CCCCCCCHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
TSQLRRHPQVYTLLALAVNLLRSVPFIILMITMIPVTLLIMGTSLGIRGAILPLVIGAAP
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FYARLVESALREVDRGVVEAAQAMGATTWQLVWRVLLPEARPGLIAGATITAIAVVGFTA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHH
MGGAIGSGGLGDVAYREGYLRSHTDVALVTVIALLMVVQLIQMFGDWLVAHYSRR
HCCCCCCCCCCHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIPMIFPSIAAPGFFVNLDADKWEDIGRATLDTLLMVGGALPPALALGLPLGIALYLCN
CCCCCCCHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
TSQLRRHPQVYTLLALAVNLLRSVPFIILMITMIPVTLLIMGTSLGIRGAILPLVIGAAP
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FYARLVESALREVDRGVVEAAQAMGATTWQLVWRVLLPEARPGLIAGATITAIAVVGFTA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHH
MGGAIGSGGLGDVAYREGYLRSHTDVALVTVIALLMVVQLIQMFGDWLVAHYSRR
HCCCCCCCCCCHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]