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The map label for this gene is corC [H]

Identifier: 182682400

GI number: 182682400

Start: 2089680

End: 2090651

Strand: Direct

Name: corC [H]

Synonym: XfasM23_1886

Alternate gene names: 182682400

Gene position: 2089680-2090651 (Clockwise)

Preceding gene: 182682399

Following gene: 182682401

Centisome position: 82.41

GC content: 55.04

Gene sequence:

>972_bases
ATGACTTTTCAGAAGCACGTAGCCCATACCCAGCCTGCTAAACTTGCAACAACGCCCAGTCCACCGGGTACTGCAACCAC
ACCTTCATTGATGTCAGAAGACGACGATCATCGCACCATTACCGAATCCCAAGAGAAACGCCGCAGCTGGCTCGAACGCC
TGAGCGCTGCATTCTCCGGAGACCCACACACCCTTGACGACCTGATGGTCATCCTGCGTAGCGCCGAACACCACGGAATC
ATCGCCACAGATACCCTGCGCATGATGGAAGGAGCGATCGCAATCGCAGACCTCACCGTCGGCGACGTGATGGTACCGCG
CTCCCAAATGGTTTCACTGCCTGTTGAATCAGACCTACAGACCATCACAAAACAAATGGTTGAATCCGGCCACTCACGCT
TCCCTGTCCACGGCGAAAATAAAGACGAAGTCCTAGGCATCCTCCTCGCCAAAGACCTGCTGCGTGGCGTATCCGCCAAC
CACACCATCACCAACGTACACGAACTACTGCGCCCCGTCGGGATGATCCCCGAATCGAAAAAACTCAACGTCCTGCTCAA
AGAATTCCGACTCTCCCACAACCATATGGCCATTGTTGTCGACGAATATGGCGGCGTTGCTGGACTCGTCACGATTGAAG
ACATACTGGAACAAATCGTCGGTGACATTGACGACGAACACGACGAAACCGAAGACCAAACCAACATGATTGCCATCCAG
GCCGACGGCTGCTACATCGTCGACGCCCTGACCCCAATTGAAGACTTCAACGAACGCTTCAACGCTGAATTTCCCGACGA
CGACTACGACACCATCGGCGGCCTAGTGACCGAAGCCATCGGACACCTACCCGAAACCGGCGACGAACTGACCATAGGTC
GATTCGCATTCCGCGTCGCCAAAGCCAATGCACGCCGGATCCACATACTCCACGTGACCGTACTTCCTCCCAACGAACAG
AACACCGCTTGA

Upstream 100 bases:

>100_bases
CCATCGAATCGATCGTACTCAACGTTTCAAACGTTACCTCACACCCTGGGAAAACCTTAGTGGGCTGTACCTACAGCCTC
GACGACCCCTAACACCTGCC

Downstream 100 bases:

>100_bases
CCGCACTCCCTCGACAGCCAACCCACCGCCTCCTGCGTGTCCTATCCCTACTCCTCTGTACCTGGCTGCTACTGACACCC
AGCGCCGCTGCCCATCCCCC

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MTFQKHVAHTQPAKLATTPSPPGTATTPSLMSEDDDHRTITESQEKRRSWLERLSAAFSGDPHTLDDLMVILRSAEHHGI
IATDTLRMMEGAIAIADLTVGDVMVPRSQMVSLPVESDLQTITKQMVESGHSRFPVHGENKDEVLGILLAKDLLRGVSAN
HTITNVHELLRPVGMIPESKKLNVLLKEFRLSHNHMAIVVDEYGGVAGLVTIEDILEQIVGDIDDEHDETEDQTNMIAIQ
ADGCYIVDALTPIEDFNERFNAEFPDDDYDTIGGLVTEAIGHLPETGDELTIGRFAFRVAKANARRIHILHVTVLPPNEQ
NTA

Sequences:

>Translated_323_residues
MTFQKHVAHTQPAKLATTPSPPGTATTPSLMSEDDDHRTITESQEKRRSWLERLSAAFSGDPHTLDDLMVILRSAEHHGI
IATDTLRMMEGAIAIADLTVGDVMVPRSQMVSLPVESDLQTITKQMVESGHSRFPVHGENKDEVLGILLAKDLLRGVSAN
HTITNVHELLRPVGMIPESKKLNVLLKEFRLSHNHMAIVVDEYGGVAGLVTIEDILEQIVGDIDDEHDETEDQTNMIAIQ
ADGCYIVDALTPIEDFNERFNAEFPDDDYDTIGGLVTEAIGHLPETGDELTIGRFAFRVAKANARRIHILHVTVLPPNEQ
NTA
>Mature_322_residues
TFQKHVAHTQPAKLATTPSPPGTATTPSLMSEDDDHRTITESQEKRRSWLERLSAAFSGDPHTLDDLMVILRSAEHHGII
ATDTLRMMEGAIAIADLTVGDVMVPRSQMVSLPVESDLQTITKQMVESGHSRFPVHGENKDEVLGILLAKDLLRGVSANH
TITNVHELLRPVGMIPESKKLNVLLKEFRLSHNHMAIVVDEYGGVAGLVTIEDILEQIVGDIDDEHDETEDQTNMIAIQA
DGCYIVDALTPIEDFNERFNAEFPDDDYDTIGGLVTEAIGHLPETGDELTIGRFAFRVAKANARRIHILHVTVLPPNEQN
TA

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=209, Percent_Identity=32.5358851674641, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI94681046, Length=185, Percent_Identity=29.1891891891892, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI40068053, Length=188, Percent_Identity=28.1914893617021, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI40068055, Length=188, Percent_Identity=28.1914893617021, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786879, Length=284, Percent_Identity=44.3661971830986, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI145693175, Length=239, Percent_Identity=28.8702928870293, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1790664, Length=256, Percent_Identity=26.171875, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082033, Length=234, Percent_Identity=28.6324786324786, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788119, Length=237, Percent_Identity=29.1139240506329, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 35626; Mature: 35494

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFQKHVAHTQPAKLATTPSPPGTATTPSLMSEDDDHRTITESQEKRRSWLERLSAAFSG
CCCHHHHCCCCCCCEECCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DPHTLDDLMVILRSAEHHGIIATDTLRMMEGAIAIADLTVGDVMVPRSQMVSLPVESDLQ
CCCCHHHHHHHHHCCCCCCEEEHHHHHHHHCCEEEEEECCCCEECCHHHHEECCCHHHHH
TITKQMVESGHSRFPVHGENKDEVLGILLAKDLLRGVSANHTITNVHELLRPVGMIPESK
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCH
KLNVLLKEFRLSHNHMAIVVDEYGGVAGLVTIEDILEQIVGDIDDEHDETEDQTNMIAIQ
HHHHHHHHHHCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
ADGCYIVDALTPIEDFNERFNAEFPDDDYDTIGGLVTEAIGHLPETGDELTIGRFAFRVA
ECCEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHH
KANARRIHILHVTVLPPNEQNTA
HCCCCEEEEEEEEEECCCCCCCC
>Mature Secondary Structure 
TFQKHVAHTQPAKLATTPSPPGTATTPSLMSEDDDHRTITESQEKRRSWLERLSAAFSG
CCHHHHCCCCCCCEECCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DPHTLDDLMVILRSAEHHGIIATDTLRMMEGAIAIADLTVGDVMVPRSQMVSLPVESDLQ
CCCCHHHHHHHHHCCCCCCEEEHHHHHHHHCCEEEEEECCCCEECCHHHHEECCCHHHHH
TITKQMVESGHSRFPVHGENKDEVLGILLAKDLLRGVSANHTITNVHELLRPVGMIPESK
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCH
KLNVLLKEFRLSHNHMAIVVDEYGGVAGLVTIEDILEQIVGDIDDEHDETEDQTNMIAIQ
HHHHHHHHHHCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
ADGCYIVDALTPIEDFNERFNAEFPDDDYDTIGGLVTEAIGHLPETGDELTIGRFAFRVA
ECCEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHH
KANARRIHILHVTVLPPNEQNTA
HCCCCEEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]