Click here to switch to the map view.

The map label for this gene is mlaA [H]

Identifier: 182682271

GI number: 182682271

Start: 1940608

End: 1941660

Strand: Direct

Name: mlaA [H]

Synonym: XfasM23_1753

Alternate gene names: 182682271

Gene position: 1940608-1941660 (Clockwise)

Preceding gene: 182682270

Following gene: 182682277

Centisome position: 76.53

GC content: 54.23

Gene sequence:

>1053_bases
ATGCATCACCCTCAAGCCTTAACTCTCATTGCATCCTCATTGTTACTGGCGGCCTGTGCCAACAAGGCAACGAAGTCCGT
CATGCCGACAGTGACTGCTTTGGACAGGTCTGCACCTGTCATGACTGTAACGCCAGCCCCTCCCACCAAGCCTCAAACGA
CGACAGTCACGCCGCAGGACGCCTCCTCCCTGGTGATGCCGACAGCAGCAGCAGATAACAACACCGCAGACAATACTCCG
ACCCAAGCGGAAGATGACTACGCTGCGCTTTACGGAGCCATTTCGCCGTCTGTTGGTCATTCCGATACAAACATACCCAG
GCCAAACGACACTCACACCACCTACGATCCTTGGGAACGCTACAACCGTGCAATGCACCAATTCAACGTCGTTATAGACC
ACAATCTCGCGCGGCCACTGGCTAACGCGTATGTACATGTCGTGCCAAAGAAGGCGCAAGTGGGTGTGACCAATTTTTTC
AATAACCTTAGCTCACCGCTGACAATGGTCAACCAAGTGCTGCAAAACCACCCAGTCTATGCATTACAGACGCTGGGCCG
GTTTCTGCTGAATTCCACGCTAGGGCTGGGCGGTCTCCTTGATCCAGCCAGCGCAGCGAAAATTCCGCGCCGCACCGAAA
ATTTTGGGCAGACTTTGGCACTTTGGGGCTGGTACAACTCACGCTACTTCGAACTTCCCCTGTTTGGGCCACGCACAGTG
CGCGACACCTTTGGCTTGGCAGGGGATCTTCCGCTGTCCCTATTACGGCAAATCGATAACAACACATGGCGTTACGGTCT
ACAGGGTCTGCAATTGGTTGACACCCGCGCTCGGCTGTTATCGTTTGACAACATACGCGACGGCGCTGTAGACGATTACG
CGCTCACACGGGACGCTTGGTTACAACGCCGCAATTACCAAATCCAAAATGCACTGCGCAAGAACAATCAGGACACGAAT
GACAATAGTGAGCTGCCCGACTACCTACGTGAAGAACATGACTCCACCACGGTACCGGTAGATGCAATGCCAATCCCGCG
CTTGAGTCGCTGA

Upstream 100 bases:

>100_bases
TGCCAACAATTGTTGCCCCTCCCGCCGGTCTGAAGGAGCTGCTCGCGGCCTATAGAATGTCCTCTGACCTGCAATTCCAG
CCCTGACCCGAAAACGTGCC

Downstream 100 bases:

>100_bases
AGACCACGCAGAACACACTAACGAGTATGGTAGTGGTGTAGTCGTGTTTCACATAGCTACCGATCAAGCTGTGATAGATC
ACTGTGGCCACTGGTTGCAA

Product: VacJ family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MHHPQALTLIASSLLLAACANKATKSVMPTVTALDRSAPVMTVTPAPPTKPQTTTVTPQDASSLVMPTAAADNNTADNTP
TQAEDDYAALYGAISPSVGHSDTNIPRPNDTHTTYDPWERYNRAMHQFNVVIDHNLARPLANAYVHVVPKKAQVGVTNFF
NNLSSPLTMVNQVLQNHPVYALQTLGRFLLNSTLGLGGLLDPASAAKIPRRTENFGQTLALWGWYNSRYFELPLFGPRTV
RDTFGLAGDLPLSLLRQIDNNTWRYGLQGLQLVDTRARLLSFDNIRDGAVDDYALTRDAWLQRRNYQIQNALRKNNQDTN
DNSELPDYLREEHDSTTVPVDAMPIPRLSR

Sequences:

>Translated_350_residues
MHHPQALTLIASSLLLAACANKATKSVMPTVTALDRSAPVMTVTPAPPTKPQTTTVTPQDASSLVMPTAAADNNTADNTP
TQAEDDYAALYGAISPSVGHSDTNIPRPNDTHTTYDPWERYNRAMHQFNVVIDHNLARPLANAYVHVVPKKAQVGVTNFF
NNLSSPLTMVNQVLQNHPVYALQTLGRFLLNSTLGLGGLLDPASAAKIPRRTENFGQTLALWGWYNSRYFELPLFGPRTV
RDTFGLAGDLPLSLLRQIDNNTWRYGLQGLQLVDTRARLLSFDNIRDGAVDDYALTRDAWLQRRNYQIQNALRKNNQDTN
DNSELPDYLREEHDSTTVPVDAMPIPRLSR
>Mature_350_residues
MHHPQALTLIASSLLLAACANKATKSVMPTVTALDRSAPVMTVTPAPPTKPQTTTVTPQDASSLVMPTAAADNNTADNTP
TQAEDDYAALYGAISPSVGHSDTNIPRPNDTHTTYDPWERYNRAMHQFNVVIDHNLARPLANAYVHVVPKKAQVGVTNFF
NNLSSPLTMVNQVLQNHPVYALQTLGRFLLNSTLGLGGLLDPASAAKIPRRTENFGQTLALWGWYNSRYFELPLFGPRTV
RDTFGLAGDLPLSLLRQIDNNTWRYGLQGLQLVDTRARLLSFDNIRDGAVDDYALTRDAWLQRRNYQIQNALRKNNQDTN
DNSELPDYLREEHDSTTVPVDAMPIPRLSR

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=228, Percent_Identity=34.6491228070175, Blast_Score=117, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 38813; Mature: 38813

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHPQALTLIASSLLLAACANKATKSVMPTVTALDRSAPVMTVTPAPPTKPQTTTVTPQD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEECCCC
ASSLVMPTAAADNNTADNTPTQAEDDYAALYGAISPSVGHSDTNIPRPNDTHTTYDPWER
CCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
YNRAMHQFNVVIDHNLARPLANAYVHVVPKKAQVGVTNFFNNLSSPLTMVNQVLQNHPVY
HHHHHHHHHEEECCHHHHHHHHCEEEEECCCHHCCHHHHHHHHCHHHHHHHHHHHCCCHH
ALQTLGRFLLNSTLGLGGLLDPASAAKIPRRTENFGQTLALWGWYNSRYFELPLFGPRTV
HHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHCCEEEEEEEECCEEEEECCCCCCHH
RDTFGLAGDLPLSLLRQIDNNTWRYGLQGLQLVDTRARLLSFDNIRDGAVDDYALTRDAW
HHHHCCCCCCHHHHHHHHCCCCEEHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LQRRNYQIQNALRKNNQDTNDNSELPDYLREEHDSTTVPVDAMPIPRLSR
HHHHCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHHPQALTLIASSLLLAACANKATKSVMPTVTALDRSAPVMTVTPAPPTKPQTTTVTPQD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEECCCC
ASSLVMPTAAADNNTADNTPTQAEDDYAALYGAISPSVGHSDTNIPRPNDTHTTYDPWER
CCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
YNRAMHQFNVVIDHNLARPLANAYVHVVPKKAQVGVTNFFNNLSSPLTMVNQVLQNHPVY
HHHHHHHHHEEECCHHHHHHHHCEEEEECCCHHCCHHHHHHHHCHHHHHHHHHHHCCCHH
ALQTLGRFLLNSTLGLGGLLDPASAAKIPRRTENFGQTLALWGWYNSRYFELPLFGPRTV
HHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHCCEEEEEEEECCEEEEECCCCCCHH
RDTFGLAGDLPLSLLRQIDNNTWRYGLQGLQLVDTRARLLSFDNIRDGAVDDYALTRDAW
HHHHCCCCCCHHHHHHHHCCCCEEHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LQRRNYQIQNALRKNNQDTNDNSELPDYLREEHDSTTVPVDAMPIPRLSR
HHHHCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]