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The map label for this gene is gcp

Identifier: 182682253

GI number: 182682253

Start: 1917901

End: 1918947

Strand: Reverse

Name: gcp

Synonym: XfasM23_1735

Alternate gene names: 182682253

Gene position: 1918947-1917901 (Counterclockwise)

Preceding gene: 182682258

Following gene: 182682252

Centisome position: 75.68

GC content: 56.06

Gene sequence:

>1047_bases
GTGAAAATCATCGGTATTGAGTCTTCATGTGATGAAACTGGCGTTGCGGTGTATGACACTGCGCTCTCTGGTTCTGCTGC
GTTACGTGCGCATTCTGTCTATAGCCAGGTTGCGTTGCATGCCGAATACGGTGGTGTGGTGCCGGAGTTGGCAAGTCGTG
ATCATGTACGTAAGTTGTTGCCATTGCTACGTCAGACGCTGGCTGAGGCCAAGCTTTCTGTTGAGGAGTTGGATGGAGTG
GCCTACACGGCCGGACCGGGTCTTGTTGGTGCGCTGTTGGTCGGTGCAGGGGTGGCACGTGCATTGGCTTGGGCACTTGA
GGTGCCGGCGATTGGGGTGCATCACATGGAAGGTCATTTGTTGTCACCGTTGCTGGAGGATGATCCACCTGAGGTGCCGT
TTGTGGCGTTGCTGGTCTCGGGTGGGCATACCCAGTTGGTTGCAGTCGATGCGATTGGTGATTACCGGTTGCTTGGTGAA
ACGTTGGACGATGCGGCTGGCGAGGCGTTTGACAAGGTTGCCAAGTTGATGGGCCTGCCGTATCCGGGAGGGCCTCAGTT
GGCTGCGTTGGCTGAACGGGGTATTCCAGGTCGATTCTGTTTCACTCGTCCGATGGTTGATCGTCCTGGGTTGGATTTCA
GCTTTTCGGGATTAAAAACTCAGGTATTGTTAGCGTGGCGCAACAGTGATCAGTCTGATGCGATTCGCGTCGATGTTGCA
CGCGGTTTTGAGGATGCTGTGGTTGATACTCTGGCGATCAAATGTGAACGTGCCTTGGATACGGTGGCTTGTCAGACGCT
GGTAGTTGCTGGCGGTGTCGGTGCCAACAAGTGCTTGCGTGCACGATTACAGGCAATGTGCAGGCAACGTGGTGGGCGTG
CTTGTTTTCCGCGTCCAGCATTGTGTACGGATAACGGTGCGATGATCGCTTTTGCCGGGGCGTTGCGTTTGCAGGCGGGT
CAGCAGAGTGATGTTGCGGTGCGTGTAACGCCGCGTTGGGATATGGCTGCGTTGCCACCGTTGGTCTCGCGGTCGTGCCG
CCGATGA

Upstream 100 bases:

>100_bases
GCGCCATAAAGAAGGAGGGATTATAAAGGCTTAAAATGTGTGTGCAAGCCTTAGGTATGTTATGTGTCCTGCAATCTAGG
CAAAAATAAATGGATGGTAT

Downstream 100 bases:

>100_bases
GTCCCTAGTTTTATAGTTGTTTACCGCGTGAAAATGTTTTCTGCACTCTGGCTTGTTTCATCTCCCCTGAAAAAATTTTT
CTATGGATAAAGTGTTTATC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKIIGIESSCDETGVAVYDTALSGSAALRAHSVYSQVALHAEYGGVVPELASRDHVRKLLPLLRQTLAEAKLSVEELDGV
AYTAGPGLVGALLVGAGVARALAWALEVPAIGVHHMEGHLLSPLLEDDPPEVPFVALLVSGGHTQLVAVDAIGDYRLLGE
TLDDAAGEAFDKVAKLMGLPYPGGPQLAALAERGIPGRFCFTRPMVDRPGLDFSFSGLKTQVLLAWRNSDQSDAIRVDVA
RGFEDAVVDTLAIKCERALDTVACQTLVVAGGVGANKCLRARLQAMCRQRGGRACFPRPALCTDNGAMIAFAGALRLQAG
QQSDVAVRVTPRWDMAALPPLVSRSCRR

Sequences:

>Translated_348_residues
MKIIGIESSCDETGVAVYDTALSGSAALRAHSVYSQVALHAEYGGVVPELASRDHVRKLLPLLRQTLAEAKLSVEELDGV
AYTAGPGLVGALLVGAGVARALAWALEVPAIGVHHMEGHLLSPLLEDDPPEVPFVALLVSGGHTQLVAVDAIGDYRLLGE
TLDDAAGEAFDKVAKLMGLPYPGGPQLAALAERGIPGRFCFTRPMVDRPGLDFSFSGLKTQVLLAWRNSDQSDAIRVDVA
RGFEDAVVDTLAIKCERALDTVACQTLVVAGGVGANKCLRARLQAMCRQRGGRACFPRPALCTDNGAMIAFAGALRLQAG
QQSDVAVRVTPRWDMAALPPLVSRSCRR
>Mature_348_residues
MKIIGIESSCDETGVAVYDTALSGSAALRAHSVYSQVALHAEYGGVVPELASRDHVRKLLPLLRQTLAEAKLSVEELDGV
AYTAGPGLVGALLVGAGVARALAWALEVPAIGVHHMEGHLLSPLLEDDPPEVPFVALLVSGGHTQLVAVDAIGDYRLLGE
TLDDAAGEAFDKVAKLMGLPYPGGPQLAALAERGIPGRFCFTRPMVDRPGLDFSFSGLKTQVLLAWRNSDQSDAIRVDVA
RGFEDAVVDTLAIKCERALDTVACQTLVVAGGVGANKCLRARLQAMCRQRGGRACFPRPALCTDNGAMIAFAGALRLQAG
QQSDVAVRVTPRWDMAALPPLVSRSCRR

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=343, Percent_Identity=31.7784256559767, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI8923380, Length=289, Percent_Identity=33.2179930795848, Blast_Score=132, Evalue=6e-31,
Organism=Escherichia coli, GI1789445, Length=339, Percent_Identity=63.1268436578171, Blast_Score=444, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17557464, Length=332, Percent_Identity=30.1204819277108, Blast_Score=140, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71995670, Length=345, Percent_Identity=31.8840579710145, Blast_Score=135, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6320099, Length=342, Percent_Identity=32.1637426900585, Blast_Score=139, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6322891, Length=296, Percent_Identity=29.7297297297297, Blast_Score=111, Evalue=1e-25,
Organism=Drosophila melanogaster, GI20129063, Length=343, Percent_Identity=33.5276967930029, Blast_Score=171, Evalue=5e-43,
Organism=Drosophila melanogaster, GI21357207, Length=296, Percent_Identity=33.1081081081081, Blast_Score=138, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_XYLF2 (B2I7X4)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830413.1
- ProteinModelPortal:   B2I7X4
- SMR:   B2I7X4
- GeneID:   6202942
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1735
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36753; Mature: 36753

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIGIESSCDETGVAVYDTALSGSAALRAHSVYSQVALHAEYGGVVPELASRDHVRKLL
CEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHH
PLLRQTLAEAKLSVEELDGVAYTAGPGLVGALLVGAGVARALAWALEVPAIGVHHMEGHL
HHHHHHHHHHHCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHH
LSPLLEDDPPEVPFVALLVSGGHTQLVAVDAIGDYRLLGETLDDAAGEAFDKVAKLMGLP
HHHHHCCCCCCCCEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
YPGGPQLAALAERGIPGRFCFTRPMVDRPGLDFSFSGLKTQVLLAWRNSDQSDAIRVDVA
CCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCEEECCCCEEEEEEECCCCCCCEEEEEHH
RGFEDAVVDTLAIKCERALDTVACQTLVVAGGVGANKCLRARLQAMCRQRGGRACFPRPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
LCTDNGAMIAFAGALRLQAGQQSDVAVRVTPRWDMAALPPLVSRSCRR
EECCCCCEEEEEEEHHCCCCCCCCEEEEEECCCCCHHCCHHHHHHCCC
>Mature Secondary Structure
MKIIGIESSCDETGVAVYDTALSGSAALRAHSVYSQVALHAEYGGVVPELASRDHVRKLL
CEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHH
PLLRQTLAEAKLSVEELDGVAYTAGPGLVGALLVGAGVARALAWALEVPAIGVHHMEGHL
HHHHHHHHHHHCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHH
LSPLLEDDPPEVPFVALLVSGGHTQLVAVDAIGDYRLLGETLDDAAGEAFDKVAKLMGLP
HHHHHCCCCCCCCEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
YPGGPQLAALAERGIPGRFCFTRPMVDRPGLDFSFSGLKTQVLLAWRNSDQSDAIRVDVA
CCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCEEECCCCEEEEEEECCCCCCCEEEEEHH
RGFEDAVVDTLAIKCERALDTVACQTLVVAGGVGANKCLRARLQAMCRQRGGRACFPRPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
LCTDNGAMIAFAGALRLQAGQQSDVAVRVTPRWDMAALPPLVSRSCRR
EECCCCCEEEEEEEHHCCCCCCCCEEEEEECCCCCHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA