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The map label for this gene is gapA [H]

Identifier: 182682236

GI number: 182682236

Start: 1898933

End: 1899937

Strand: Direct

Name: gapA [H]

Synonym: XfasM23_1718

Alternate gene names: 182682236

Gene position: 1898933-1899937 (Clockwise)

Preceding gene: 182682228

Following gene: 182682241

Centisome position: 74.89

GC content: 49.45

Gene sequence:

>1005_bases
ATGGCAATCAAGGTCGGTATCAACGGTTTCGGTCGCATTGGACGCAACATATTACGCTCTGCAGTACAAAACTTCGGCAG
TAACATTGATATCGTAGCCATTAATGACCTGCTAGAAGCAGATTATTTGGCATACATGTTGCAGTACGACTCAGTGCATG
GACGCTTTAAAGGAGAGATCGCAATTGAGGGAACTGCACTCATCCTTAACGGCAAGAAGATTCGCCTAACAGCCGAACGT
GATCCAGGCAATCTTCAATGGGCTGATGCCGGTGCTGAAATAGTGATCGAATCTACCGGACTATTCCTGACGCAGGAAAG
TGCCGGGAAACATCTCGCAGCCGGCGCCAAGAAGGTCATCATCTCAGCACCTTCAAAAGACGAAACACCCATGTTCGTGT
ACGGCGTCAATCACAACAGCTACAACGGGGAACCAATCGTCTCGAATGCTTCATGCACCACCAATTGCTTGGCACCACTG
GCTAAAGTCATCAACGACAAATGGGGCATTACGCGCGGTTTAATGACCACTGTACATGCGGCCACTGCGACACAAAAAAC
TGTCGACGGCCCATCCAATAAAGACTGGCGCGGTGGACGCGGGATTCTTGAGAACATCATCCCATCTTCAACTGGAGCAG
CAAAAGCTGTTGGGAAAGTGATCCCATCACTCAACGGGAAACTCACCGGGATGAGCTTCCGCGTCCCCACCTCGGATGTT
TCTGTCGTGGACTTGACTGTCCAATTAAACACCCCAGCAACTTACAAAGAAATCTGCACAGAGGTGAAGCAGCAAAGTGA
GGGGCCGTTGAGGGGCATCCTGGGCTATACAGAAGACAAAGTGGTAGCCACCGACTTCCGCGGTGAAACCTGTACCTGCG
TATTCGATGCGGATGCTGGCATTGCACTAGATCCGACATTTATCAAACTCATTGCTTGGTACGACAACGAATGGGGTTAT
TCAAACAAGTGCTTAGAAATCGCCAAAGTCATTGCAGCTAAATAA

Upstream 100 bases:

>100_bases
TATATAACAACAGGTCGATACCTCATCACAGGACAGGCACTGCTAGAATGGATGCTTCCTCCACACGCTGCCCCGCCGGG
GCCATCAGGAATTCGTGAAC

Downstream 100 bases:

>100_bases
GCTAAAGTGAATCAACACAAGACACGGCAATTCGATTAACGCAATATGGTTTATCTGTTGACCCCAACCATCTCTAGCAT
GTTGTGTTATTGGTGCTTGA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAIKVGINGFGRIGRNILRSAVQNFGSNIDIVAINDLLEADYLAYMLQYDSVHGRFKGEIAIEGTALILNGKKIRLTAER
DPGNLQWADAGAEIVIESTGLFLTQESAGKHLAAGAKKVIISAPSKDETPMFVYGVNHNSYNGEPIVSNASCTTNCLAPL
AKVINDKWGITRGLMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGKVIPSLNGKLTGMSFRVPTSDV
SVVDLTVQLNTPATYKEICTEVKQQSEGPLRGILGYTEDKVVATDFRGETCTCVFDADAGIALDPTFIKLIAWYDNEWGY
SNKCLEIAKVIAAK

Sequences:

>Translated_334_residues
MAIKVGINGFGRIGRNILRSAVQNFGSNIDIVAINDLLEADYLAYMLQYDSVHGRFKGEIAIEGTALILNGKKIRLTAER
DPGNLQWADAGAEIVIESTGLFLTQESAGKHLAAGAKKVIISAPSKDETPMFVYGVNHNSYNGEPIVSNASCTTNCLAPL
AKVINDKWGITRGLMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGKVIPSLNGKLTGMSFRVPTSDV
SVVDLTVQLNTPATYKEICTEVKQQSEGPLRGILGYTEDKVVATDFRGETCTCVFDADAGIALDPTFIKLIAWYDNEWGY
SNKCLEIAKVIAAK
>Mature_333_residues
AIKVGINGFGRIGRNILRSAVQNFGSNIDIVAINDLLEADYLAYMLQYDSVHGRFKGEIAIEGTALILNGKKIRLTAERD
PGNLQWADAGAEIVIESTGLFLTQESAGKHLAAGAKKVIISAPSKDETPMFVYGVNHNSYNGEPIVSNASCTTNCLAPLA
KVINDKWGITRGLMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGKVIPSLNGKLTGMSFRVPTSDVS
VVDLTVQLNTPATYKEICTEVKQQSEGPLRGILGYTEDKVVATDFRGETCTCVFDADAGIALDPTFIKLIAWYDNEWGYS
NKCLEIAKVIAAK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=63.1736526946108, Blast_Score=431, Evalue=1e-121,
Organism=Homo sapiens, GI7657116, Length=335, Percent_Identity=55.2238805970149, Blast_Score=387, Evalue=1e-108,
Organism=Escherichia coli, GI1788079, Length=327, Percent_Identity=69.1131498470948, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI1789295, Length=335, Percent_Identity=37.0149253731343, Blast_Score=244, Evalue=5e-66,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=60.9467455621302, Blast_Score=415, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17568413, Length=338, Percent_Identity=60.9467455621302, Blast_Score=414, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=58.8757396449704, Blast_Score=400, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=58.2840236686391, Blast_Score=399, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6322409, Length=332, Percent_Identity=59.9397590361446, Blast_Score=411, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6322468, Length=332, Percent_Identity=59.9397590361446, Blast_Score=409, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6321631, Length=332, Percent_Identity=59.6385542168675, Blast_Score=408, Evalue=1e-115,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=62.1621621621622, Blast_Score=422, Evalue=1e-118,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=62.1621621621622, Blast_Score=422, Evalue=1e-118,
Organism=Drosophila melanogaster, GI17933600, Length=333, Percent_Identity=61.8618618618619, Blast_Score=421, Evalue=1e-118,
Organism=Drosophila melanogaster, GI18110149, Length=333, Percent_Identity=61.8618618618619, Blast_Score=421, Evalue=1e-118,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=58.1538461538462, Blast_Score=372, Evalue=1e-103,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35799; Mature: 35668

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKVGINGFGRIGRNILRSAVQNFGSNIDIVAINDLLEADYLAYMLQYDSVHGRFKGEI
CEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEEE
AIEGTALILNGKKIRLTAERDPGNLQWADAGAEIVIESTGLFLTQESAGKHLAAGAKKVI
EEEEEEEEEECCEEEEEECCCCCCEEEECCCCEEEEEECCEEEECCCCCCCHHCCCEEEE
ISAPSKDETPMFVYGVNHNSYNGEPIVSNASCTTNCLAPLAKVINDKWGITRGLMTTVHA
EECCCCCCCCEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
ATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGKVIPSLNGKLTGMSFRVPTSDV
HHHCHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCC
SVVDLTVQLNTPATYKEICTEVKQQSEGPLRGILGYTEDKVVATDFRGETCTCVFDADAG
EEEEEEEEECCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCEEEEECCCCEEEEEEECCCC
IALDPTFIKLIAWYDNEWGYSNKCLEIAKVIAAK
CEECHHHEEEEEEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AIKVGINGFGRIGRNILRSAVQNFGSNIDIVAINDLLEADYLAYMLQYDSVHGRFKGEI
EEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEEE
AIEGTALILNGKKIRLTAERDPGNLQWADAGAEIVIESTGLFLTQESAGKHLAAGAKKVI
EEEEEEEEEECCEEEEEECCCCCCEEEECCCCEEEEEECCEEEECCCCCCCHHCCCEEEE
ISAPSKDETPMFVYGVNHNSYNGEPIVSNASCTTNCLAPLAKVINDKWGITRGLMTTVHA
EECCCCCCCCEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
ATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGKVIPSLNGKLTGMSFRVPTSDV
HHHCHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCC
SVVDLTVQLNTPATYKEICTEVKQQSEGPLRGILGYTEDKVVATDFRGETCTCVFDADAG
EEEEEEEEECCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCEEEEECCCCEEEEEEECCCC
IALDPTFIKLIAWYDNEWGYSNKCLEIAKVIAAK
CEECHHHEEEEEEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852; 8366033 [H]