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The map label for this gene is aceE

Identifier: 182682112

GI number: 182682112

Start: 1761774

End: 1764464

Strand: Direct

Name: aceE

Synonym: XfasM23_1590

Alternate gene names: 182682112

Gene position: 1761774-1764464 (Clockwise)

Preceding gene: 182682103

Following gene: 182682125

Centisome position: 69.48

GC content: 55.67

Gene sequence:

>2691_bases
ATGAACCGGTTGAAAGAAGCACTGCACAACGATCCAAACCCGCTAGAAACCCAGGAATGGCTCGAATCGATCAAGGCCGT
CATCGACATCGCCGGTCCCGAACGTGCACACCAATTACTGGAAGGAGTCGCCGAACAGATTCACCGTACTGGCACCAACC
TACCCTTCTCCCCCATCACCGAATACGTCAACACAATTCCCACAGCCGACGAAGCCAAAAACCCCGGCGACCCCGCATTA
GAACGCAGCATCCGCTCCATCATCCGTTGGAATGCGATGGCGACCGTCGTACGCGCCAATCGCAAGCCTGGCGACCTCGG
CGGCCACATCGCCTCCTTCGCATCTTCAGCCACACTCTACGACGTCGGATTCAACCACTTCTGGCGCGCACCCAGCCCCC
AACATCCTGGCGACCTGTTATACATCCAAGGTCATAGCTCCCCGGGCATCTATGCACGCGCCTTCCTCGAAGGCCGGATC
AGCGAAAGCCAACTCGACCACTTCCGTATGGAAGTCGATGGCAAAGGCATCTCCTCTTACCCCCACCCCTGGCTGATGCC
GCAATTCTGGCAGACACCCACCGTATCAATGGGCCTGGGTCCACTGAGTGCCATCTACCAAGCCCAATTCATGAAATACC
TGGAACACCGCGGCCTGATCGCCCCATCCGACCGCAAAGTATGGTGCTTCATCGGCGATGGCGAAAGCGATGAACCAGAA
ACATTAGGCGCCATTGCACTCGCCGGCCGCGAAGGCTTAGACAACTTGATCTTTGTAGTCAATTGCAACCTGCAACGGCT
AGATGGCCCTGTCCGTGGCAACGGCAAAATTATCCAAGAACTGGAAGGCGTCTTCCGCGGCGGTGGCTGGAATGTCATCA
AACTACTGTGGGGAGCGCACTGGGACCCACTCCTGGCCCAAGACACCCAAGGCGTGCTGCGCAAACTGATGATGGAAACC
GTCGATGGCGAATACCAAAACTGCAAAGCATTCGGTGGCGAATACACCCGTAAACACTTCTTCGATAAGTACCCAGAAAC
GGCTGCGATGGTCGCCCACCTATCCGATAACGACATCTGGCGCCTCAACCGTGGCGGCCACGACCCACACAAGATTTATG
CTGCCTACCATCGCGCGGTCAACACCCAAGGCATGCCTACCGTCATCCTAGCCAAGACCGTCAAAGGCTACGGCATGGGG
ACCGCCGGCGAATCACTGAACCCCACACATCAAACCAAAAAGCTGGACCACGACGCAATCAAACACTTCCGTGACCGATT
CAACATCCCAATCAGCGACCAACAATTGGACGCAGCGGATCAAATTCCGTTCTACCACCCTGGCCCGGATTCGCCGGAAA
TAAAGTACATGCTTGCCCGCCGTGAAGCCTTGGGCGGCTTCCTCCCGCAACGTCGCACCAAATCCAGCAAATCATTCATC
GTCCCTGGCCTAGACAAGTACGAACGCCTCCTCACCTCAAGCGGCGAACGCACCTACTCTACAACCATGGCGTTTGTACA
AAGCCTCAACATCACCCTACGCGACAAAGCACTCGGTCCCCACATCGTACCGATCGTCGCCGACGAAGCACGCACCTTCG
GTATGGAAGGCCTCTTCCGCCAGATCGGCATCTATGCCCCATTCGGCCAAAAATACAAACCAGTCGACGCCGATCAATTG
ATGTACTACCGCGAAGATGAATCCGGCCAAGTACTGCAACAAGGCATCACCGAACCTGGAGCAATCGCCTCATGGATGGC
TGCCGGCACCAGCTACTCCGTGTCTGATGTCCCCATGCTGCCGTTTTACATCTACTACTCCATGTTTGGCTTCCAACGCA
TCGGCGATATCGCCTGGCAAGCCGCAGACATGCGCACCCGCGGCTTCCTACTTGGAGGCACTGCTGGCCGCACCACATTG
AACGGCGAAGGCCTACAACACGAAGATGGCCACAGCCATCTGATGGCCGGTGCAATCCCCAACGTACGCAGCTACGACCC
CACCTTTGGTTACGAAGTCACCGTGATCCTGCAACATGGCATGAAAGCAATGATGCAAGACCAAATCGACGAGTACTACT
ACCTAACCTTGATGAACGAAAACTACGCCCATCCGGACATGCCAGCCGGCGCAGAACAAGGCATCATCAAAGGCATGTAC
CTGCTCAAAGACGCCGGAAAACCAAAAAAAGGCGAACTGCGCGTGCAATTACTGGGTTCAGGCACCATCTTGCGCGAAGC
TATTGCTGCTGCCGAATTACTCCATCAAGATTTTGGTATCACTGCCGATATCTGGTCCTGCCCCAGCTTTAGCGAATTAC
GCAAAGATGGCTTTGATGCAGAACGATGGAACCGCCTCCATCCAGACAACCAACCGCGTACACCCTACGTCACCCAACAA
CTGGAAAACCGTCAGGGACCGGCCATTGCCGCAACAGATTACGTACGTCTGTTCGCCGACCAAATCCGTGCTTTTGTACC
GATGCACTACACCGTCCTTGGCACCGATGGCTTCGGGCGCAGCGATACCCGCAGCAACCTGCGCCGCTTCTTCGAAGTGG
ACCGCTACTTTATCGCCCACGCCGCGATTGCCGCATTAGCCAAAGAAGGCAAAATGACCGGGAAAGACGTTGCACGTGCC
ATTGAGCAATACAACATCAATCCGGAGAAACTAAACCCAGTAGACACCTGA

Upstream 100 bases:

>100_bases
GCGATGTAGCCAGGAATGCAATTGAACCAGTGCGTTACACTTACGCATCCAAACATATTTAACGCTTAGCGCATGCGCGC
GCGAAGCCCTGGGAATACTA

Downstream 100 bases:

>100_bases
GGTCTTGCCAAAGTAAACACCCTCAACCGTGCTGGATTGAACCACATCACCACCCACCCCTAACATCCTGTGAAACGTTG
CAGAAAACTCACAATGATGA

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 896; Mature: 896

Protein sequence:

>896_residues
MNRLKEALHNDPNPLETQEWLESIKAVIDIAGPERAHQLLEGVAEQIHRTGTNLPFSPITEYVNTIPTADEAKNPGDPAL
ERSIRSIIRWNAMATVVRANRKPGDLGGHIASFASSATLYDVGFNHFWRAPSPQHPGDLLYIQGHSSPGIYARAFLEGRI
SESQLDHFRMEVDGKGISSYPHPWLMPQFWQTPTVSMGLGPLSAIYQAQFMKYLEHRGLIAPSDRKVWCFIGDGESDEPE
TLGAIALAGREGLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGVFRGGGWNVIKLLWGAHWDPLLAQDTQGVLRKLMMET
VDGEYQNCKAFGGEYTRKHFFDKYPETAAMVAHLSDNDIWRLNRGGHDPHKIYAAYHRAVNTQGMPTVILAKTVKGYGMG
TAGESLNPTHQTKKLDHDAIKHFRDRFNIPISDQQLDAADQIPFYHPGPDSPEIKYMLARREALGGFLPQRRTKSSKSFI
VPGLDKYERLLTSSGERTYSTTMAFVQSLNITLRDKALGPHIVPIVADEARTFGMEGLFRQIGIYAPFGQKYKPVDADQL
MYYREDESGQVLQQGITEPGAIASWMAAGTSYSVSDVPMLPFYIYYSMFGFQRIGDIAWQAADMRTRGFLLGGTAGRTTL
NGEGLQHEDGHSHLMAGAIPNVRSYDPTFGYEVTVILQHGMKAMMQDQIDEYYYLTLMNENYAHPDMPAGAEQGIIKGMY
LLKDAGKPKKGELRVQLLGSGTILREAIAAAELLHQDFGITADIWSCPSFSELRKDGFDAERWNRLHPDNQPRTPYVTQQ
LENRQGPAIAATDYVRLFADQIRAFVPMHYTVLGTDGFGRSDTRSNLRRFFEVDRYFIAHAAIAALAKEGKMTGKDVARA
IEQYNINPEKLNPVDT

Sequences:

>Translated_896_residues
MNRLKEALHNDPNPLETQEWLESIKAVIDIAGPERAHQLLEGVAEQIHRTGTNLPFSPITEYVNTIPTADEAKNPGDPAL
ERSIRSIIRWNAMATVVRANRKPGDLGGHIASFASSATLYDVGFNHFWRAPSPQHPGDLLYIQGHSSPGIYARAFLEGRI
SESQLDHFRMEVDGKGISSYPHPWLMPQFWQTPTVSMGLGPLSAIYQAQFMKYLEHRGLIAPSDRKVWCFIGDGESDEPE
TLGAIALAGREGLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGVFRGGGWNVIKLLWGAHWDPLLAQDTQGVLRKLMMET
VDGEYQNCKAFGGEYTRKHFFDKYPETAAMVAHLSDNDIWRLNRGGHDPHKIYAAYHRAVNTQGMPTVILAKTVKGYGMG
TAGESLNPTHQTKKLDHDAIKHFRDRFNIPISDQQLDAADQIPFYHPGPDSPEIKYMLARREALGGFLPQRRTKSSKSFI
VPGLDKYERLLTSSGERTYSTTMAFVQSLNITLRDKALGPHIVPIVADEARTFGMEGLFRQIGIYAPFGQKYKPVDADQL
MYYREDESGQVLQQGITEPGAIASWMAAGTSYSVSDVPMLPFYIYYSMFGFQRIGDIAWQAADMRTRGFLLGGTAGRTTL
NGEGLQHEDGHSHLMAGAIPNVRSYDPTFGYEVTVILQHGMKAMMQDQIDEYYYLTLMNENYAHPDMPAGAEQGIIKGMY
LLKDAGKPKKGELRVQLLGSGTILREAIAAAELLHQDFGITADIWSCPSFSELRKDGFDAERWNRLHPDNQPRTPYVTQQ
LENRQGPAIAATDYVRLFADQIRAFVPMHYTVLGTDGFGRSDTRSNLRRFFEVDRYFIAHAAIAALAKEGKMTGKDVARA
IEQYNINPEKLNPVDT
>Mature_896_residues
MNRLKEALHNDPNPLETQEWLESIKAVIDIAGPERAHQLLEGVAEQIHRTGTNLPFSPITEYVNTIPTADEAKNPGDPAL
ERSIRSIIRWNAMATVVRANRKPGDLGGHIASFASSATLYDVGFNHFWRAPSPQHPGDLLYIQGHSSPGIYARAFLEGRI
SESQLDHFRMEVDGKGISSYPHPWLMPQFWQTPTVSMGLGPLSAIYQAQFMKYLEHRGLIAPSDRKVWCFIGDGESDEPE
TLGAIALAGREGLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGVFRGGGWNVIKLLWGAHWDPLLAQDTQGVLRKLMMET
VDGEYQNCKAFGGEYTRKHFFDKYPETAAMVAHLSDNDIWRLNRGGHDPHKIYAAYHRAVNTQGMPTVILAKTVKGYGMG
TAGESLNPTHQTKKLDHDAIKHFRDRFNIPISDQQLDAADQIPFYHPGPDSPEIKYMLARREALGGFLPQRRTKSSKSFI
VPGLDKYERLLTSSGERTYSTTMAFVQSLNITLRDKALGPHIVPIVADEARTFGMEGLFRQIGIYAPFGQKYKPVDADQL
MYYREDESGQVLQQGITEPGAIASWMAAGTSYSVSDVPMLPFYIYYSMFGFQRIGDIAWQAADMRTRGFLLGGTAGRTTL
NGEGLQHEDGHSHLMAGAIPNVRSYDPTFGYEVTVILQHGMKAMMQDQIDEYYYLTLMNENYAHPDMPAGAEQGIIKGMY
LLKDAGKPKKGELRVQLLGSGTILREAIAAAELLHQDFGITADIWSCPSFSELRKDGFDAERWNRLHPDNQPRTPYVTQQ
LENRQGPAIAATDYVRLFADQIRAFVPMHYTVLGTDGFGRSDTRSNLRRFFEVDRYFIAHAAIAALAKEGKMTGKDVARA
IEQYNINPEKLNPVDT

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=893, Percent_Identity=56.5509518477044, Blast_Score=1055, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 100216; Mature: 100216

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLKEALHNDPNPLETQEWLESIKAVIDIAGPERAHQLLEGVAEQIHRTGTNLPFSPIT
CCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
EYVNTIPTADEAKNPGDPALERSIRSIIRWNAMATVVRANRKPGDLGGHIASFASSATLY
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEE
DVGFNHFWRAPSPQHPGDLLYIQGHSSPGIYARAFLEGRISESQLDHFRMEVDGKGISSY
ECCHHHHCCCCCCCCCCCEEEEEECCCCCCEEHHHHHCCCCHHHHHHEEEEECCCCCCCC
PHPWLMPQFWQTPTVSMGLGPLSAIYQAQFMKYLEHRGLIAPSDRKVWCFIGDGESDEPE
CCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCH
TLGAIALAGREGLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGVFRGGGWNVIKLLWGAH
HHHHEEECCCCCCCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCC
WDPLLAQDTQGVLRKLMMETVDGEYQNCKAFGGEYTRKHFFDKYPETAAMVAHLSDNDIW
CCCHHHCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHCCCCHHHHEEECCCCCEE
RLNRGGHDPHKIYAAYHRAVNTQGMPTVILAKTVKGYGMGTAGESLNPTHQTKKLDHDAI
EECCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCCCCCCCCCHHHHHCCHHHH
KHFRDRFNIPISDQQLDAADQIPFYHPGPDSPEIKYMLARREALGGFLPQRRTKSSKSFI
HHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCEE
VPGLDKYERLLTSSGERTYSTTMAFVQSLNITLRDKALGPHIVPIVADEARTFGMEGLFR
CCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCCCCEEEEEEECCHHHHCHHHHHH
QIGIYAPFGQKYKPVDADQLMYYREDESGQVLQQGITEPGAIASWMAAGTSYSVSDVPML
HHCCCCCCCCCCCCCCHHHEEEEEECCCHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCHH
PFYIYYSMFGFQRIGDIAWQAADMRTRGFLLGGTAGRTTLNGEGLQHEDGHSHLMAGAIP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEECCCCCCCCCCCCCEEECCCC
NVRSYDPTFGYEVTVILQHGMKAMMQDQIDEYYYLTLMNENYAHPDMPAGAEQGIIKGMY
CCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
LLKDAGKPKKGELRVQLLGSGTILREAIAAAELLHQDFGITADIWSCPSFSELRKDGFDA
HHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHCCCCH
ERWNRLHPDNQPRTPYVTQQLENRQGPAIAATDYVRLFADQIRAFVPMHYTVLGTDGFGR
HHHCCCCCCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCEEEEEEECCCCCC
SDTRSNLRRFFEVDRYFIAHAAIAALAKEGKMTGKDVARAIEQYNINPEKLNPVDT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHCCCCCCC
>Mature Secondary Structure
MNRLKEALHNDPNPLETQEWLESIKAVIDIAGPERAHQLLEGVAEQIHRTGTNLPFSPIT
CCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
EYVNTIPTADEAKNPGDPALERSIRSIIRWNAMATVVRANRKPGDLGGHIASFASSATLY
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEE
DVGFNHFWRAPSPQHPGDLLYIQGHSSPGIYARAFLEGRISESQLDHFRMEVDGKGISSY
ECCHHHHCCCCCCCCCCCEEEEEECCCCCCEEHHHHHCCCCHHHHHHEEEEECCCCCCCC
PHPWLMPQFWQTPTVSMGLGPLSAIYQAQFMKYLEHRGLIAPSDRKVWCFIGDGESDEPE
CCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCH
TLGAIALAGREGLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGVFRGGGWNVIKLLWGAH
HHHHEEECCCCCCCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCC
WDPLLAQDTQGVLRKLMMETVDGEYQNCKAFGGEYTRKHFFDKYPETAAMVAHLSDNDIW
CCCHHHCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHCCCCHHHHEEECCCCCEE
RLNRGGHDPHKIYAAYHRAVNTQGMPTVILAKTVKGYGMGTAGESLNPTHQTKKLDHDAI
EECCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCCCCCCCCCHHHHHCCHHHH
KHFRDRFNIPISDQQLDAADQIPFYHPGPDSPEIKYMLARREALGGFLPQRRTKSSKSFI
HHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCEE
VPGLDKYERLLTSSGERTYSTTMAFVQSLNITLRDKALGPHIVPIVADEARTFGMEGLFR
CCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCCCCEEEEEEECCHHHHCHHHHHH
QIGIYAPFGQKYKPVDADQLMYYREDESGQVLQQGITEPGAIASWMAAGTSYSVSDVPML
HHCCCCCCCCCCCCCCHHHEEEEEECCCHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCHH
PFYIYYSMFGFQRIGDIAWQAADMRTRGFLLGGTAGRTTLNGEGLQHEDGHSHLMAGAIP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEECCCCCCCCCCCCCEEECCCC
NVRSYDPTFGYEVTVILQHGMKAMMQDQIDEYYYLTLMNENYAHPDMPAGAEQGIIKGMY
CCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
LLKDAGKPKKGELRVQLLGSGTILREAIAAAELLHQDFGITADIWSCPSFSELRKDGFDA
HHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHCCCCH
ERWNRLHPDNQPRTPYVTQQLENRQGPAIAATDYVRLFADQIRAFVPMHYTVLGTDGFGR
HHHCCCCCCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCEEEEEEECCCCCC
SDTRSNLRRFFEVDRYFIAHAAIAALAKEGKMTGKDVARAIEQYNINPEKLNPVDT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9171401; 10984043 [H]