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The map label for this gene is fabD [H]

Identifier: 182682111

GI number: 182682111

Start: 1760327

End: 1761280

Strand: Reverse

Name: fabD [H]

Synonym: XfasM23_1589

Alternate gene names: 182682111

Gene position: 1761280-1760327 (Counterclockwise)

Preceding gene: 182682113

Following gene: 182682110

Centisome position: 69.46

GC content: 54.51

Gene sequence:

>954_bases
ATGATGCCCGTGACAGAGTCTATTTTCGCTTTCGTTTTTCCAGGTCAGGGTTCTCAGTCTCTTGGCATGCTTTCCGAGTT
TGCTGTGCTCTATCCGGAGATTCTCGATACTTTCGCTGAGGCATCTGAGGGAGCTGGTGTGGATCTTTGGACGTTGTCGC
AACGTGGGCCTGAGGAGATGTTGAACCGTACTGAGTACACTCAGCCAGCGTTGTTGGCCGCCAGTGTGGCGCTATGGCGG
CTTTGGCAGGCTCGCGGTGGCCGTGCACCGGATCTGTTTGCTGGTCACAGTTTGGGGGAGTACAGCGCTTTGGTAGCGGC
TGGTGCATTGTCATTGAAGGATGGTGCTTATTTGGTAAGGTTGCGCGGTCAGTTAATGCAGGATGCGGTTGCTGTGGGTG
TCGGTGCGATGGCCGCGGTCCTGGGTGCTGAGGATGCTTTGGTGGCTGAGGTTTGTGCGCAGGTTGCGGGAAGCGAGATT
GTCGTCCCAGCCAATTTTAATTCGCCGGTGCAGGTGGTGATTGGTGGTCATGCCACGGCGGTTGATCGTGCGCTGGTGTT
GTTGGCAGAACGTGGTGTGTCTAAAACAGTCAAGTTGGCAGTGAGTGTGCCGTCGCATACGCCACTAATGCGTGATGCTG
CGCATCGTCTCGCTGAGGCGATGCTTGGGTTGGTTTGGAAGGTGCCGCAGATTCCGGTAGTGCAGAATGTTGATGGCAGA
GTGCATGACGGTGTTGAAGCGATCCGTGAGGCTCTGGTCAAGCAGCTTTATCTGCCAGTTCAGTGGACGGATTGTGTGAG
AGAGTTGGCTACGTGTGGTGTGGTACATATCGCTGAATGTGGTCCTGGTAAGGTGCTTATGGGACTCATTAGGCGTATCG
ATAAAACATTGGATGTGCGTTCGTTGGCGACTCCAACGGGGTTCTCTGATGTCTTGGACGAGTGGGTTTTTTGA

Upstream 100 bases:

>100_bases
TGAGTGGTTTTCGTGTTTTATCCGGTTGATGCATACGTGTCGGTACGGGCGATGTGATGGTTTTGCCCGTATGATCGGAG
CTTGTCTTTACTTTTGATCC

Downstream 100 bases:

>100_bases
ATTGTTTTCTAATGAAAATGGTTGGTGTAGTTTCAGTTTCAGGGCTTGCTCTTAAGTTCTTTGTTGCCGTTATGCGGTGT
TATCCACTCATTTGAGGAAC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MMPVTESIFAFVFPGQGSQSLGMLSEFAVLYPEILDTFAEASEGAGVDLWTLSQRGPEEMLNRTEYTQPALLAASVALWR
LWQARGGRAPDLFAGHSLGEYSALVAAGALSLKDGAYLVRLRGQLMQDAVAVGVGAMAAVLGAEDALVAEVCAQVAGSEI
VVPANFNSPVQVVIGGHATAVDRALVLLAERGVSKTVKLAVSVPSHTPLMRDAAHRLAEAMLGLVWKVPQIPVVQNVDGR
VHDGVEAIREALVKQLYLPVQWTDCVRELATCGVVHIAECGPGKVLMGLIRRIDKTLDVRSLATPTGFSDVLDEWVF

Sequences:

>Translated_317_residues
MMPVTESIFAFVFPGQGSQSLGMLSEFAVLYPEILDTFAEASEGAGVDLWTLSQRGPEEMLNRTEYTQPALLAASVALWR
LWQARGGRAPDLFAGHSLGEYSALVAAGALSLKDGAYLVRLRGQLMQDAVAVGVGAMAAVLGAEDALVAEVCAQVAGSEI
VVPANFNSPVQVVIGGHATAVDRALVLLAERGVSKTVKLAVSVPSHTPLMRDAAHRLAEAMLGLVWKVPQIPVVQNVDGR
VHDGVEAIREALVKQLYLPVQWTDCVRELATCGVVHIAECGPGKVLMGLIRRIDKTLDVRSLATPTGFSDVLDEWVF
>Mature_317_residues
MMPVTESIFAFVFPGQGSQSLGMLSEFAVLYPEILDTFAEASEGAGVDLWTLSQRGPEEMLNRTEYTQPALLAASVALWR
LWQARGGRAPDLFAGHSLGEYSALVAAGALSLKDGAYLVRLRGQLMQDAVAVGVGAMAAVLGAEDALVAEVCAQVAGSEI
VVPANFNSPVQVVIGGHATAVDRALVLLAERGVSKTVKLAVSVPSHTPLMRDAAHRLAEAMLGLVWKVPQIPVVQNVDGR
VHDGVEAIREALVKQLYLPVQWTDCVRELATCGVVHIAECGPGKVLMGLIRRIDKTLDVRSLATPTGFSDVLDEWVF

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=30.1003344481605, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=39.4495412844037, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787334, Length=305, Percent_Identity=52.7868852459016, Blast_Score=317, Evalue=8e-88,
Organism=Caenorhabditis elegans, GI71984332, Length=274, Percent_Identity=30.2919708029197, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17550940, Length=285, Percent_Identity=29.4736842105263, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=32.2259136212625, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33763; Mature: 33763

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPVTESIFAFVFPGQGSQSLGMLSEFAVLYPEILDTFAEASEGAGVDLWTLSQRGPEEM
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHH
LNRTEYTQPALLAASVALWRLWQARGGRAPDLFAGHSLGEYSALVAAGALSLKDGAYLVR
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHH
LRGQLMQDAVAVGVGAMAAVLGAEDALVAEVCAQVAGSEIVVPANFNSPVQVVIGGHATA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCHHH
VDRALVLLAERGVSKTVKLAVSVPSHTPLMRDAAHRLAEAMLGLVWKVPQIPVVQNVDGR
HHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCC
VHDGVEAIREALVKQLYLPVQWTDCVRELATCGVVHIAECGPGKVLMGLIRRIDKTLDVR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHH
SLATPTGFSDVLDEWVF
HHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MMPVTESIFAFVFPGQGSQSLGMLSEFAVLYPEILDTFAEASEGAGVDLWTLSQRGPEEM
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHH
LNRTEYTQPALLAASVALWRLWQARGGRAPDLFAGHSLGEYSALVAAGALSLKDGAYLVR
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHH
LRGQLMQDAVAVGVGAMAAVLGAEDALVAEVCAQVAGSEIVVPANFNSPVQVVIGGHATA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCHHH
VDRALVLLAERGVSKTVKLAVSVPSHTPLMRDAAHRLAEAMLGLVWKVPQIPVVQNVDGR
HHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCC
VHDGVEAIREALVKQLYLPVQWTDCVRELATCGVVHIAECGPGKVLMGLIRRIDKTLDVR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHH
SLATPTGFSDVLDEWVF
HHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]