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The map label for this gene is ybdL [H]

Identifier: 182682081

GI number: 182682081

Start: 1732976

End: 1734208

Strand: Reverse

Name: ybdL [H]

Synonym: XfasM23_1559

Alternate gene names: 182682081

Gene position: 1734208-1732976 (Counterclockwise)

Preceding gene: 182682092

Following gene: 182682080

Centisome position: 68.39

GC content: 53.45

Gene sequence:

>1233_bases
ATGTTGCGGTCCATGGGGCGGTACTCGGATACACATTCAGTAGACTTTGCGTTCTTTTATGTTCTGACGAGAGATAAGTC
CTTCATGCAGGTCACGAGTAAGTTACCCCAAGTGGGGACCACGATATTTAGTGTGATGTCGCAGTTGGCGGATGTGTATG
GGGCGGTCAATTTAGGGCAGGGGTTTCCGGATTTTCCGGTGCCGTTGCGTTTGCAGGAGGCGTTGGCGGGTGCGGTGCGT
GAGGGACACAATCAGTATCCGCCGATGATTGGGGTGGCTGGGTTGCGTCAGGGAATCGCTGCGAAGGTGTTGCGCTGTTA
CGGTGCGCAGGTGGATGCGGATGTTGAGATCACGGTGACCAGTGGGGCGACGGAGGCGATTTTTAATGCAATCCATGCGG
TGGTGGGGGCGGGTGATGAGGTCATTGTGCTTGATCCAGCGTATGACTGTTATGAGCCGGGGATTGTGTTGGCCGGTGCG
CGTGCGGTGCATGTGCCATTGGATGCGGTGAGTTTTAAGGTGGATTGGGAGCGGGTGGGTGCGGCGATCACGTCAAGAAC
GCGGTTGTTGATCGTGAATAGTCCGCATAATCCGTCCGGGGCGTTGTTTTCAGCCGATGATATGCGGGCTTTAGCGGCTT
TGTTGGATGGGACGGATATTTTGCTGATTTCCGATGAGGTGTATGAGCATATTGTGTTTGATGGGTGTGGCCATGAGTCG
GTGTTGCGTTGGCCGCAGTTGCGTGCGCGTGCGTTTGTGATTTCTAGTTTCGGTAAAACCTATCATTGCACCGGATGGAA
AATCGGTTATGCGATTGCACCGTCGGCGCTTAGTGCGGAGTTTCGTAAGGTCCATCAATACAACACGTTTACTAGTTTTG
GACCGGCGCAATATGCGTTTGCTGCGATGTTGCATGAGGAGCCTGGGTATGTGGAGCAGGTTGGTTTGTTCTATCAGGCA
AGACGGGATTGTTTCCGTGAGCAGTTGTTGACAACCAAGTTAGTGCCGTTGCCTGTGTCGGGAGGTTATTTTCAGTTGGT
GGATTATGGGGCGGTCAGTGATTTGTCTGATGTGGAGTTTTCAAGGTGGTTAGCGGTGGAAAAGGGGGTGGCGTCGATTC
CGTTATCGCCGTTCTATGAGACTGCTCCAGCGGGGCAGCGTTTGGTGCGGTTGTGTTTCGCTAAAAATGATATGACGTTG
GGGGCGGCGATCGAGCGGTTACAACGGCTTTGA

Upstream 100 bases:

>100_bases
TGCGATTGGGAAGCACGCGATATGTGGCAGGCAGGTGAATGCGGGGGCATTGTATCGCGGCATGGTGTGTGGAGCGGTGT
GGTGGGCAGGTGTATGGTGG

Downstream 100 bases:

>100_bases
TGTGGAGGATGTGATGCAGGATTTGCGTATTTCTCTTGTTCAAGGTGAGACGCGGTGGCATGACGCAGCGGGTAATCGGC
ATTACTACGGTGCGCTGTTG

Product: putative aminotransferase

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MLRSMGRYSDTHSVDFAFFYVLTRDKSFMQVTSKLPQVGTTIFSVMSQLADVYGAVNLGQGFPDFPVPLRLQEALAGAVR
EGHNQYPPMIGVAGLRQGIAAKVLRCYGAQVDADVEITVTSGATEAIFNAIHAVVGAGDEVIVLDPAYDCYEPGIVLAGA
RAVHVPLDAVSFKVDWERVGAAITSRTRLLIVNSPHNPSGALFSADDMRALAALLDGTDILLISDEVYEHIVFDGCGHES
VLRWPQLRARAFVISSFGKTYHCTGWKIGYAIAPSALSAEFRKVHQYNTFTSFGPAQYAFAAMLHEEPGYVEQVGLFYQA
RRDCFREQLLTTKLVPLPVSGGYFQLVDYGAVSDLSDVEFSRWLAVEKGVASIPLSPFYETAPAGQRLVRLCFAKNDMTL
GAAIERLQRL

Sequences:

>Translated_410_residues
MLRSMGRYSDTHSVDFAFFYVLTRDKSFMQVTSKLPQVGTTIFSVMSQLADVYGAVNLGQGFPDFPVPLRLQEALAGAVR
EGHNQYPPMIGVAGLRQGIAAKVLRCYGAQVDADVEITVTSGATEAIFNAIHAVVGAGDEVIVLDPAYDCYEPGIVLAGA
RAVHVPLDAVSFKVDWERVGAAITSRTRLLIVNSPHNPSGALFSADDMRALAALLDGTDILLISDEVYEHIVFDGCGHES
VLRWPQLRARAFVISSFGKTYHCTGWKIGYAIAPSALSAEFRKVHQYNTFTSFGPAQYAFAAMLHEEPGYVEQVGLFYQA
RRDCFREQLLTTKLVPLPVSGGYFQLVDYGAVSDLSDVEFSRWLAVEKGVASIPLSPFYETAPAGQRLVRLCFAKNDMTL
GAAIERLQRL
>Mature_410_residues
MLRSMGRYSDTHSVDFAFFYVLTRDKSFMQVTSKLPQVGTTIFSVMSQLADVYGAVNLGQGFPDFPVPLRLQEALAGAVR
EGHNQYPPMIGVAGLRQGIAAKVLRCYGAQVDADVEITVTSGATEAIFNAIHAVVGAGDEVIVLDPAYDCYEPGIVLAGA
RAVHVPLDAVSFKVDWERVGAAITSRTRLLIVNSPHNPSGALFSADDMRALAALLDGTDILLISDEVYEHIVFDGCGHES
VLRWPQLRARAFVISSFGKTYHCTGWKIGYAIAPSALSAEFRKVHQYNTFTSFGPAQYAFAAMLHEEPGYVEQVGLFYQA
RRDCFREQLLTTKLVPLPVSGGYFQLVDYGAVSDLSDVEFSRWLAVEKGVASIPLSPFYETAPAGQRLVRLCFAKNDMTL
GAAIERLQRL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=400, Percent_Identity=33, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI56713256, Length=400, Percent_Identity=33, Blast_Score=225, Evalue=6e-59,
Organism=Homo sapiens, GI95147551, Length=396, Percent_Identity=33.5858585858586, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI169881279, Length=396, Percent_Identity=33.5858585858586, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI169881281, Length=394, Percent_Identity=28.6802030456853, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI4507369, Length=335, Percent_Identity=25.0746268656716, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1786816, Length=378, Percent_Identity=54.4973544973545, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI1788722, Length=393, Percent_Identity=25.4452926208651, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788627, Length=178, Percent_Identity=28.6516853932584, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=407, Percent_Identity=33.6609336609337, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI71994476, Length=407, Percent_Identity=33.6609336609337, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17567369, Length=403, Percent_Identity=32.0099255583127, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17567663, Length=349, Percent_Identity=22.0630372492837, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=31.1053984575836, Blast_Score=181, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28573069, Length=392, Percent_Identity=32.1428571428571, Blast_Score=205, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24646114, Length=392, Percent_Identity=32.1428571428571, Blast_Score=205, Evalue=4e-53,
Organism=Drosophila melanogaster, GI28573067, Length=392, Percent_Identity=32.1428571428571, Blast_Score=205, Evalue=4e-53,
Organism=Drosophila melanogaster, GI28573065, Length=392, Percent_Identity=32.1428571428571, Blast_Score=205, Evalue=4e-53,
Organism=Drosophila melanogaster, GI18859735, Length=186, Percent_Identity=29.5698924731183, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 44836; Mature: 44836

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRSMGRYSDTHSVDFAFFYVLTRDKSFMQVTSKLPQVGTTIFSVMSQLADVYGAVNLGQ
CCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCC
GFPDFPVPLRLQEALAGAVREGHNQYPPMIGVAGLRQGIAAKVLRCYGAQVDADVEITVT
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
SGATEAIFNAIHAVVGAGDEVIVLDPAYDCYEPGIVLAGARAVHVPLDAVSFKVDWERVG
CCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEECCEEEEECHHHEEEEECHHHHH
AAITSRTRLLIVNSPHNPSGALFSADDMRALAALLDGTDILLISDEVYEHIVFDGCGHES
HHHHCCEEEEEEECCCCCCCCEECHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCHH
VLRWPQLRARAFVISSFGKTYHCTGWKIGYAIAPSALSAEFRKVHQYNTFTSFGPAQYAF
HHHCHHHHHHHHHHHHCCCEEEECCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHH
AAMLHEEPGYVEQVGLFYQARRDCFREQLLTTKLVPLPVSGGYFQLVDYGAVSDLSDVEF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEEEEECCCCCCCCHHHH
SRWLAVEKGVASIPLSPFYETAPAGQRLVRLCFAKNDMTLGAAIERLQRL
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLRSMGRYSDTHSVDFAFFYVLTRDKSFMQVTSKLPQVGTTIFSVMSQLADVYGAVNLGQ
CCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCC
GFPDFPVPLRLQEALAGAVREGHNQYPPMIGVAGLRQGIAAKVLRCYGAQVDADVEITVT
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
SGATEAIFNAIHAVVGAGDEVIVLDPAYDCYEPGIVLAGARAVHVPLDAVSFKVDWERVG
CCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEECCEEEEECHHHEEEEECHHHHH
AAITSRTRLLIVNSPHNPSGALFSADDMRALAALLDGTDILLISDEVYEHIVFDGCGHES
HHHHCCEEEEEEECCCCCCCCEECHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCHH
VLRWPQLRARAFVISSFGKTYHCTGWKIGYAIAPSALSAEFRKVHQYNTFTSFGPAQYAF
HHHCHHHHHHHHHHHHCCCEEEECCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHH
AAMLHEEPGYVEQVGLFYQARRDCFREQLLTTKLVPLPVSGGYFQLVDYGAVSDLSDVEF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEEEEECCCCCCCCHHHH
SRWLAVEKGVASIPLSPFYETAPAGQRLVRLCFAKNDMTLGAAIERLQRL
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]