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The map label for this gene is obgE

Identifier: 182682047

GI number: 182682047

Start: 1693665

End: 1694738

Strand: Reverse

Name: obgE

Synonym: XfasM23_1525

Alternate gene names: 182682047

Gene position: 1694738-1693665 (Counterclockwise)

Preceding gene: 182682048

Following gene: 182682045

Centisome position: 66.84

GC content: 52.98

Gene sequence:

>1074_bases
ATGAAGTTTGTCGACGAAGCAGAAATTCAAGTGATCGCCGGAAACGGTGGAGATGGTTGCGTTAGCTTCCGCCGCGAGAA
ATTTATCCCTCTTGGTGGTCCTGATGGTGGCGACGGAGGTGATGGTGGCAGCGTCTGGCTAGTTGCCGATGAAAACCTCA
ATACCCTGGTGGATTTTCGTCACGAACGTATTTTTAAAGCGCAACGCGGTGTGAATGGAATGGGCCAGCAGATGTACGGT
AAGGCTGGCCAGGACAAAATTATCAGCGTGCCGATTGGGACCGTGGTGATCAATGTCCAGACGGATGAGGTCATCGGCGA
TATGGTCCGTCATGGTGATCGCTTACTGGTGGCCAAGGGAGGCACAGGCGGCTTAGGTAATATGCATTTCAAAAGCTCGA
TCAACCGTGCTCCACGCCAAGCAAGGCCTGGAGAGCAGGGCGAAGAGCGTACCTTGAAACTGGAACTCAAGTTGCTTGCT
GATATTGGGATGCTTGGTTTCCCAAACGTTGGCAAAAGCACCTTCATTCGTGCAGTCTCTGCTGCCACCCCGAAAGTGGC
TGACTACCCATTTACCACGCTCTATCCCAACCTGGGCGTGGTCAAAATTGAAGCCTACAGCAGCTTCGTGATCGCTGATG
TTCCTGGCTTGATCGAAGGAGCCGCTGATGGTGTAGGGCTTGGCATGCAGTTCCTGCGTCACTTGCAGCGTACTAAGTTG
CTGCTGCATATGGTGGATATTTCCGCAACTGCTGATGCTTACGGTAACGAAAAAGTGGGGGTAGGTCTGTTACCCATTGA
GCAGGTTCGTAAACTCGAAATCGAACTCGAACGCCACGACCCAGCATTGCTAGATAAACCGCGCTGGCTAGTGTTGAACA
AGGCTGACTTGATGCCCCAGGAAGAGGCCCAGGCCCTAGCAGAGGCACTGATTGCCGAGCTTCGTTGGACTGCGCCCTGG
TACCTTGTGTCTGCTGTGAGCCGTGAAGGGACTTGGCCAATTATGAAGAGTGCAATGACACTTTTTGAGCATCAGCGCGA
GGTGGCCGCTGAGCAAAGAGTAAGCAGCAGATGA

Upstream 100 bases:

>100_bases
TGTCTTCTTTGTAAACCTGTTACGTGTTTGCGTGCGGTTCTGTACGTATAAACTGCTTGGTTCCATCGTCTTTCGCTTTC
CAATTCCGAATCCGTATTCC

Downstream 100 bases:

>100_bases
CGCAGGGAAGGTGCCCTAGAGGGATTTGCCTTTTCATCAATCAAACTGGCCGTACCCTGTTCTATAGGGAGCTACGGCCA
GTGCGATGCATCGCTCCCTG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MKFVDEAEIQVIAGNGGDGCVSFRREKFIPLGGPDGGDGGDGGSVWLVADENLNTLVDFRHERIFKAQRGVNGMGQQMYG
KAGQDKIISVPIGTVVINVQTDEVIGDMVRHGDRLLVAKGGTGGLGNMHFKSSINRAPRQARPGEQGEERTLKLELKLLA
DIGMLGFPNVGKSTFIRAVSAATPKVADYPFTTLYPNLGVVKIEAYSSFVIADVPGLIEGAADGVGLGMQFLRHLQRTKL
LLHMVDISATADAYGNEKVGVGLLPIEQVRKLEIELERHDPALLDKPRWLVLNKADLMPQEEAQALAEALIAELRWTAPW
YLVSAVSREGTWPIMKSAMTLFEHQREVAAEQRVSSR

Sequences:

>Translated_357_residues
MKFVDEAEIQVIAGNGGDGCVSFRREKFIPLGGPDGGDGGDGGSVWLVADENLNTLVDFRHERIFKAQRGVNGMGQQMYG
KAGQDKIISVPIGTVVINVQTDEVIGDMVRHGDRLLVAKGGTGGLGNMHFKSSINRAPRQARPGEQGEERTLKLELKLLA
DIGMLGFPNVGKSTFIRAVSAATPKVADYPFTTLYPNLGVVKIEAYSSFVIADVPGLIEGAADGVGLGMQFLRHLQRTKL
LLHMVDISATADAYGNEKVGVGLLPIEQVRKLEIELERHDPALLDKPRWLVLNKADLMPQEEAQALAEALIAELRWTAPW
YLVSAVSREGTWPIMKSAMTLFEHQREVAAEQRVSSR
>Mature_357_residues
MKFVDEAEIQVIAGNGGDGCVSFRREKFIPLGGPDGGDGGDGGSVWLVADENLNTLVDFRHERIFKAQRGVNGMGQQMYG
KAGQDKIISVPIGTVVINVQTDEVIGDMVRHGDRLLVAKGGTGGLGNMHFKSSINRAPRQARPGEQGEERTLKLELKLLA
DIGMLGFPNVGKSTFIRAVSAATPKVADYPFTTLYPNLGVVKIEAYSSFVIADVPGLIEGAADGVGLGMQFLRHLQRTKL
LLHMVDISATADAYGNEKVGVGLLPIEQVRKLEIELERHDPALLDKPRWLVLNKADLMPQEEAQALAEALIAELRWTAPW
YLVSAVSREGTWPIMKSAMTLFEHQREVAAEQRVSSR

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=303, Percent_Identity=41.5841584158416, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI111955139, Length=293, Percent_Identity=36.8600682593857, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI111955063, Length=149, Percent_Identity=39.5973154362416, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4557537, Length=129, Percent_Identity=31.7829457364341, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789574, Length=352, Percent_Identity=57.1022727272727, Blast_Score=355, Evalue=2e-99,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=36, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=349, Percent_Identity=39.2550143266476, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17552324, Length=369, Percent_Identity=27.9132791327913, Blast_Score=134, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17509631, Length=145, Percent_Identity=30.3448275862069, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555344, Length=165, Percent_Identity=31.5151515151515, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=189, Percent_Identity=37.037037037037, Blast_Score=116, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6321649, Length=140, Percent_Identity=32.1428571428571, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319281, Length=90, Percent_Identity=35.5555555555556, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24585318, Length=299, Percent_Identity=38.1270903010033, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI20129375, Length=324, Percent_Identity=38.5802469135802, Blast_Score=162, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_XYLF2 (B2I6V6)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830207.1
- ProteinModelPortal:   B2I6V6
- SMR:   B2I6V6
- GeneID:   6202572
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1525
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- ProtClustDB:   PRK12299
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 38893; Mature: 38893

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEAEIQVIAGNGGDGCVSFRREKFIPLGGPDGGDGGDGGSVWLVADENLNTLVDFR
CCCCCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHH
HERIFKAQRGVNGMGQQMYGKAGQDKIISVPIGTVVINVQTDEVIGDMVRHGDRLLVAKG
HHHHHHHHCCCCCCCHHHHCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHCCCEEEEEEC
GTGGLGNMHFKSSINRAPRQARPGEQGEERTLKLELKLLADIGMLGFPNVGKSTFIRAVS
CCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEHHHCCCCCCCCCCHHHHHHHHH
AATPKVADYPFTTLYPNLGVVKIEAYSSFVIADVPGLIEGAADGVGLGMQFLRHLQRTKL
CCCCCCCCCCCHHHCCCCCEEEEECCCCEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHH
LLHMVDISATADAYGNEKVGVGLLPIEQVRKLEIELERHDPALLDKPRWLVLNKADLMPQ
HHHHHHHCCCCCCCCCCCCCEEECCHHHHHEEEEEEECCCCCHHCCCCEEEEECCCCCCH
EEAQALAEALIAELRWTAPWYLVSAVSREGTWPIMKSAMTLFEHQREVAAEQRVSSR
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFVDEAEIQVIAGNGGDGCVSFRREKFIPLGGPDGGDGGDGGSVWLVADENLNTLVDFR
CCCCCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHH
HERIFKAQRGVNGMGQQMYGKAGQDKIISVPIGTVVINVQTDEVIGDMVRHGDRLLVAKG
HHHHHHHHCCCCCCCHHHHCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHCCCEEEEEEC
GTGGLGNMHFKSSINRAPRQARPGEQGEERTLKLELKLLADIGMLGFPNVGKSTFIRAVS
CCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEHHHCCCCCCCCCCHHHHHHHHH
AATPKVADYPFTTLYPNLGVVKIEAYSSFVIADVPGLIEGAADGVGLGMQFLRHLQRTKL
CCCCCCCCCCCHHHCCCCCEEEEECCCCEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHH
LLHMVDISATADAYGNEKVGVGLLPIEQVRKLEIELERHDPALLDKPRWLVLNKADLMPQ
HHHHHHHCCCCCCCCCCCCCEEECCHHHHHEEEEEEECCCCCHHCCCCEEEEECCCCCCH
EEAQALAEALIAELRWTAPWYLVSAVSREGTWPIMKSAMTLFEHQREVAAEQRVSSR
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA