Click here to switch to the map view.

The map label for this gene is mdtA [H]

Identifier: 182682013

GI number: 182682013

Start: 1644006

End: 1645241

Strand: Direct

Name: mdtA [H]

Synonym: XfasM23_1488

Alternate gene names: 182682013

Gene position: 1644006-1645241 (Clockwise)

Preceding gene: 182682011

Following gene: 182682014

Centisome position: 64.83

GC content: 54.61

Gene sequence:

>1236_bases
ATGCCATATTTTTTAAAAATCTCCCTGCTTGCCGCAGCACTCATGACCACGTCATGCAGCCAAGGCGACAAGAATAGTGC
ACATCCTGCTGGCGCTGACAACACACAAAGCGTTGAGAAACAGGGGGATAACGCTCCAATTCCTGTCACAGTAGTCGCAG
CAAGCAGCCAAAATGTTCCTGTGTACGCTGCCGCCCCAGGCACAGTGGCCGCAATGAATACCGTCACGATTAACCCGCAG
GTCAGTGGTCAATTGATCAGCCTACACTTCCGCGAGGGTGAATCAGTAAAAAAAGGCCAATTACTCGCCGAAATTGACGC
ACGCGCACTTCAGGCCAGCTACGATCAAGCCGCAGCGGCGAAGCGTCAGAACCAAGCACTGCTGGCAACCGCACGTGCCA
ACTACACCCGCTCCAGCACGTTGGAATACCAACCGTACGTCGCCAAGACAGAATTAGATACACAACATAACCAGGTCACG
CAGTATGAAGCGGCAGTCGCAGCAAACGAAGCCGCAATGCGAGCAGCCCAAGTACAGCTGCAATACACTAAGATTGTCGC
ACCGATCGACGGCGTCGCCGGGATCCGCAGCGTAGATGCTGGGAACGTGGTCACAACTAGCACCTCCATCGTGACACTGA
CACAGATGCATCCAATCTACGTCTCATTCAATCTTCCCGAGCGCTTGTTGCAGGAAGTACGCCAAGCCCATGCCTCCGGC
CCCGTGATGGTGGCCGCGCTGGACCGCGGAGATGCACACCCACTGACCGAAGATGGCACATTGGATGCGATCAATAACCA
AATAAACACTGATAGCGGCACTTTCAGCGCACGTGCCGTGTTCTCCAACCGCAATAACGCACTATGGCCTGGCCAGTTCG
TCAACGCGCGTCTGCAACTACGTACGATTGCCAATGGTGTCGTGATTCCGGCGCAAGCAGTGCAACGCGGCCCCAATGGC
GACTACGTTTACCTTGTCAAGCAAGATCACACGGTCGTTACTCAGGAAGTCACCCAAGGTGTGGAAATCGGTGACAGCCA
TGTACAAATCGCCAAAGGCTTGAATGTCGGCGACACAGTAGTCACAGAAGGTCAATTCCGGCTCAAACCAGGCAGTAAAG
TCATCGCGCTAGCACCAGGTGAAACTCCACCAGCACCAACCGAAGCCGAATTGAAGGCTGCTGCGGAAAAACGCAGCAAA
AATAGCATGGGTGGTCCTCCTCGCGGCGGCCCATAA

Upstream 100 bases:

>100_bases
TCCGTTCACCAGCTCCTGAAAATGCTATAGCATGGCGTCAACCTGAGGATATAGTGATGCCGAACACACCAACTGTCTCT
ACGGCATCCAGGATTGAGTA

Downstream 100 bases:

>100_bases
TTCCGACGTTGTTCATTCTGTAACGCGTTTTCTCCAACTGACGTTATTTGTCAAGGACACACCACGTGGGCTTTTCGACG
ATCTTTATCCGCCGCCCAAT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MPYFLKISLLAAALMTTSCSQGDKNSAHPAGADNTQSVEKQGDNAPIPVTVVAASSQNVPVYAAAPGTVAAMNTVTINPQ
VSGQLISLHFREGESVKKGQLLAEIDARALQASYDQAAAAKRQNQALLATARANYTRSSTLEYQPYVAKTELDTQHNQVT
QYEAAVAANEAAMRAAQVQLQYTKIVAPIDGVAGIRSVDAGNVVTTSTSIVTLTQMHPIYVSFNLPERLLQEVRQAHASG
PVMVAALDRGDAHPLTEDGTLDAINNQINTDSGTFSARAVFSNRNNALWPGQFVNARLQLRTIANGVVIPAQAVQRGPNG
DYVYLVKQDHTVVTQEVTQGVEIGDSHVQIAKGLNVGDTVVTEGQFRLKPGSKVIALAPGETPPAPTEAELKAAAEKRSK
NSMGGPPRGGP

Sequences:

>Translated_411_residues
MPYFLKISLLAAALMTTSCSQGDKNSAHPAGADNTQSVEKQGDNAPIPVTVVAASSQNVPVYAAAPGTVAAMNTVTINPQ
VSGQLISLHFREGESVKKGQLLAEIDARALQASYDQAAAAKRQNQALLATARANYTRSSTLEYQPYVAKTELDTQHNQVT
QYEAAVAANEAAMRAAQVQLQYTKIVAPIDGVAGIRSVDAGNVVTTSTSIVTLTQMHPIYVSFNLPERLLQEVRQAHASG
PVMVAALDRGDAHPLTEDGTLDAINNQINTDSGTFSARAVFSNRNNALWPGQFVNARLQLRTIANGVVIPAQAVQRGPNG
DYVYLVKQDHTVVTQEVTQGVEIGDSHVQIAKGLNVGDTVVTEGQFRLKPGSKVIALAPGETPPAPTEAELKAAAEKRSK
NSMGGPPRGGP
>Mature_410_residues
PYFLKISLLAAALMTTSCSQGDKNSAHPAGADNTQSVEKQGDNAPIPVTVVAASSQNVPVYAAAPGTVAAMNTVTINPQV
SGQLISLHFREGESVKKGQLLAEIDARALQASYDQAAAAKRQNQALLATARANYTRSSTLEYQPYVAKTELDTQHNQVTQ
YEAAVAANEAAMRAAQVQLQYTKIVAPIDGVAGIRSVDAGNVVTTSTSIVTLTQMHPIYVSFNLPERLLQEVRQAHASGP
VMVAALDRGDAHPLTEDGTLDAINNQINTDSGTFSARAVFSNRNNALWPGQFVNARLQLRTIANGVVIPAQAVQRGPNGD
YVYLVKQDHTVVTQEVTQGVEIGDSHVQIAKGLNVGDTVVTEGQFRLKPGSKVIALAPGETPPAPTEAELKAAAEKRSKN
SMGGPPRGGP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=331, Percent_Identity=42.2960725075529, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI1789929, Length=386, Percent_Identity=30.8290155440415, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1786668, Length=355, Percent_Identity=31.5492957746479, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1789665, Length=388, Percent_Identity=32.4742268041237, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87081796, Length=342, Percent_Identity=28.9473684210526, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI87081951, Length=161, Percent_Identity=31.6770186335404, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43420; Mature: 43289

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYFLKISLLAAALMTTSCSQGDKNSAHPAGADNTQSVEKQGDNAPIPVTVVAASSQNVP
CCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCE
VYAAAPGTVAAMNTVTINPQVSGQLISLHFREGESVKKGQLLAEIDARALQASYDQAAAA
EEEECCCCEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KRQNQALLATARANYTRSSTLEYQPYVAKTELDTQHNQVTQYEAAVAANEAAMRAAQVQL
HHCCCEEEEEECCCCCCCCCEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEEE
QYTKIVAPIDGVAGIRSVDAGNVVTTSTSIVTLTQMHPIYVSFNLPERLLQEVRQAHASG
EEEEEEECCCCCCCCCCCCCCCEEEECCEEEEEEEECEEEEEECCHHHHHHHHHHHHCCC
PVMVAALDRGDAHPLTEDGTLDAINNQINTDSGTFSARAVFSNRNNALWPGQFVNARLQL
CEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCHHHCCEEEE
RTIANGVVIPAQAVQRGPNGDYVYLVKQDHTVVTQEVTQGVEIGDSHVQIAKGLNVGDTV
EEECCCEEEEHHHHHCCCCCCEEEEEECCCEEEEHHHHCCCCCCCCEEEEECCCCCCCEE
VTEGQFRLKPGSKVIALAPGETPPAPTEAELKAAAEKRSKNSMGGPPRGGP
EECCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PYFLKISLLAAALMTTSCSQGDKNSAHPAGADNTQSVEKQGDNAPIPVTVVAASSQNVP
CEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCE
VYAAAPGTVAAMNTVTINPQVSGQLISLHFREGESVKKGQLLAEIDARALQASYDQAAAA
EEEECCCCEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KRQNQALLATARANYTRSSTLEYQPYVAKTELDTQHNQVTQYEAAVAANEAAMRAAQVQL
HHCCCEEEEEECCCCCCCCCEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEEE
QYTKIVAPIDGVAGIRSVDAGNVVTTSTSIVTLTQMHPIYVSFNLPERLLQEVRQAHASG
EEEEEEECCCCCCCCCCCCCCCEEEECCEEEEEEEECEEEEEECCHHHHHHHHHHHHCCC
PVMVAALDRGDAHPLTEDGTLDAINNQINTDSGTFSARAVFSNRNNALWPGQFVNARLQL
CEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCHHHCCEEEE
RTIANGVVIPAQAVQRGPNGDYVYLVKQDHTVVTQEVTQGVEIGDSHVQIAKGLNVGDTV
EEECCCEEEEHHHHHCCCCCCEEEEEECCCEEEEHHHHCCCCCCCCEEEEECCCCCCCEE
VTEGQFRLKPGSKVIALAPGETPPAPTEAELKAAAEKRSKNSMGGPPRGGP
EECCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA