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The map label for this gene is apaH

Identifier: 182681825

GI number: 182681825

Start: 1420917

End: 1421804

Strand: Direct

Name: apaH

Synonym: XfasM23_1290

Alternate gene names: 182681825

Gene position: 1420917-1421804 (Clockwise)

Preceding gene: 182681824

Following gene: 182681826

Centisome position: 56.04

GC content: 53.94

Gene sequence:

>888_bases
ATGAGCATCTGGGCCATCGGCGACCTGCAAGGCTGCTACGACGCCACCCAACGTTTGCTAGAAAATATCCGCTTCGACCC
TTCACAGGATACGTTGTGGTTTTGCGGCGACTTAGTCAATCGCGGCGGTCAATCGTTGGAAACGCTACGCTTAGTGCATT
CACTCCGCAGCCACAGCGTCGTCGTACTGGGTAACCACGATCTTTCCCTATTAGCAGTTACCGTACGCAGCGAAGAAGAA
CAACGCAAGGTCAATCCCGATCTGCTACGCATCATCACCGCTGAAGATCGCGACGAAATACTGACCTGGCTACGCATGCA
AAAACTGATCCATGTTGATCGCACCATCGGCTGGATGATGGTGCATGCAGGATTAGCGCCGAAGTGGACAACTCAGATGG
CAGAGAAGCTAGCACACGAGGTAGAACAGCAACTACACGGCACCGACTACCGTAAGCTACTGCACAGTATGTATGGCGAC
AAACCGGAATGGTCGCCAGCGCTAAGCGGCTGCAACCGCAGCCGTGCAATCATCAACGTGCTAACACGCATGCGCTACTG
CACTCCACGCGGGCGAATCTCTACCGAAGACAAAGGAACACCAGGGACGCAAACTCAAGGTATGTATCCGTGGTTTGAAG
TCCCAGGCAGGGTTGAACGTGATCTGAAGATCGTCTGCGGCCATTGGTCGACGCTAGGATTGACCATCACTCAAGGTATC
CACGCAATCGACACTGGTGCAGTCTGGGGCGGAAAACTCACTGCATTACAGATCGACACCGACGAATTACGCCTAGCACA
GGTACACGGCCTGTCAATCGAACATCCGCGACACACGCACACACCGCGTCGAAAAGCAAAAAAGCGCCACAAACGCTCCC
CAAAGTAG

Upstream 100 bases:

>100_bases
ATTACGACATGATGGCCGATGACGGTACCGAATTCACCGCCACAATCTCCCCATTCGTACTCAGTGTGCCGCGAACACTA
CACTGACGGAGGCGCAATAG

Downstream 100 bases:

>100_bases
TGGACGAACATCACTTATTTCTATAACCCAAGTGGTATGTTGCCAAGACAAGACAAAAACTCGTAAAAATGAGCGGCTTG
TCGATGAAGCATCCACCAAA

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MSIWAIGDLQGCYDATQRLLENIRFDPSQDTLWFCGDLVNRGGQSLETLRLVHSLRSHSVVVLGNHDLSLLAVTVRSEEE
QRKVNPDLLRIITAEDRDEILTWLRMQKLIHVDRTIGWMMVHAGLAPKWTTQMAEKLAHEVEQQLHGTDYRKLLHSMYGD
KPEWSPALSGCNRSRAIINVLTRMRYCTPRGRISTEDKGTPGTQTQGMYPWFEVPGRVERDLKIVCGHWSTLGLTITQGI
HAIDTGAVWGGKLTALQIDTDELRLAQVHGLSIEHPRHTHTPRRKAKKRHKRSPK

Sequences:

>Translated_295_residues
MSIWAIGDLQGCYDATQRLLENIRFDPSQDTLWFCGDLVNRGGQSLETLRLVHSLRSHSVVVLGNHDLSLLAVTVRSEEE
QRKVNPDLLRIITAEDRDEILTWLRMQKLIHVDRTIGWMMVHAGLAPKWTTQMAEKLAHEVEQQLHGTDYRKLLHSMYGD
KPEWSPALSGCNRSRAIINVLTRMRYCTPRGRISTEDKGTPGTQTQGMYPWFEVPGRVERDLKIVCGHWSTLGLTITQGI
HAIDTGAVWGGKLTALQIDTDELRLAQVHGLSIEHPRHTHTPRRKAKKRHKRSPK
>Mature_294_residues
SIWAIGDLQGCYDATQRLLENIRFDPSQDTLWFCGDLVNRGGQSLETLRLVHSLRSHSVVVLGNHDLSLLAVTVRSEEEQ
RKVNPDLLRIITAEDRDEILTWLRMQKLIHVDRTIGWMMVHAGLAPKWTTQMAEKLAHEVEQQLHGTDYRKLLHSMYGDK
PEWSPALSGCNRSRAIINVLTRMRYCTPRGRISTEDKGTPGTQTQGMYPWFEVPGRVERDLKIVCGHWSTLGLTITQGIH
AIDTGAVWGGKLTALQIDTDELRLAQVHGLSIEHPRHTHTPRRKAKKRHKRSPK

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family

Homologues:

Organism=Escherichia coli, GI1786234, Length=259, Percent_Identity=44.015444015444, Blast_Score=220, Evalue=9e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APAH_XYLF2 (B2I5R6)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829985.1
- ProteinModelPortal:   B2I5R6
- SMR:   B2I5R6
- GeneID:   6203854
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1290
- HOGENOM:   HBG724457
- OMA:   LVFGHWA
- ProtClustDB:   PRK00166
- HAMAP:   MF_00199
- InterPro:   IPR004617
- InterPro:   IPR004843
- PIRSF:   PIRSF000903
- TIGRFAMs:   TIGR00668

Pfam domain/function: PF00149 Metallophos

EC number: =3.6.1.41

Molecular weight: Translated: 33637; Mature: 33506

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIWAIGDLQGCYDATQRLLENIRFDPSQDTLWFCGDLVNRGGQSLETLRLVHSLRSHSV
CCEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCE
VVLGNHDLSLLAVTVRSEEEQRKVNPDLLRIITAEDRDEILTWLRMQKLIHVDRTIGWMM
EEEECCCCEEEEEEECCCHHHHCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
VHAGLAPKWTTQMAEKLAHEVEQQLHGTDYRKLLHSMYGDKPEWSPALSGCNRSRAIINV
HHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHH
LTRMRYCTPRGRISTEDKGTPGTQTQGMYPWFEVPGRVERDLKIVCGHWSTLGLTITQGI
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCEEEEECCCCHHCEEHHCCC
HAIDTGAVWGGKLTALQIDTDELRLAQVHGLSIEHPRHTHTPRRKAKKRHKRSPK
CEECCCCCCCCEEEEEEECHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
SIWAIGDLQGCYDATQRLLENIRFDPSQDTLWFCGDLVNRGGQSLETLRLVHSLRSHSV
CEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCE
VVLGNHDLSLLAVTVRSEEEQRKVNPDLLRIITAEDRDEILTWLRMQKLIHVDRTIGWMM
EEEECCCCEEEEEEECCCHHHHCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
VHAGLAPKWTTQMAEKLAHEVEQQLHGTDYRKLLHSMYGDKPEWSPALSGCNRSRAIINV
HHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHH
LTRMRYCTPRGRISTEDKGTPGTQTQGMYPWFEVPGRVERDLKIVCGHWSTLGLTITQGI
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCEEEEECCCCHHCEEHHCCC
HAIDTGAVWGGKLTALQIDTDELRLAQVHGLSIEHPRHTHTPRRKAKKRHKRSPK
CEECCCCCCCCEEEEEEECHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA