Click here to switch to the map view.

The map label for this gene is 182681675

Identifier: 182681675

GI number: 182681675

Start: 1279607

End: 1280389

Strand: Direct

Name: 182681675

Synonym: XfasM23_1133

Alternate gene names: NA

Gene position: 1279607-1280389 (Clockwise)

Preceding gene: 182681670

Following gene: 182681676

Centisome position: 50.46

GC content: 53.51

Gene sequence:

>783_bases
ATGCACACCATGACAAGACCAGACCAAGCCCGCACCCCATGGTATTTGTTGTCACTACGTCCGGCAAACAACCACGCCGC
ACTGCGCCGTGCCGTCGCGCGTTACGGAGGAGGATTAATCGCACTATCCCCGTGGCGATTAAAGCGTCTAGACAGTCCAG
AGACACGCTCTGCATTAGCATCAGCATTGACGGCATCAACCCTGGTTTTCACCAGTCCAGAGGCAGTACGTGCGGCACAT
GCTCTGCAAACGCTACGCACTTCACCTGGACAAGTATGGTTGTGCGTTGGCGCAAGCACTGCACGCGTGCTACAACAGTG
CGGTATTACACGCGTGTTGCACCCAACACAAATGAACAGTGAAGGGTTACTCACATTACTGGCACAGCAACCCCCAACCG
AAGTTGGACTTATTACCGCACCAGGAGGACGTGATTTACTCCAGCAGAAGCTTTTAGAAAATGGCATACGGTTACATCGT
GCCGATGTCTACGAACGTCAACCGTTACGTCTGCGCACAGCCACATTGGATACACTCCAGCGTAATGCCACACGTAGCCT
GCTTGCACTGAGCAGTGCCGAAGCTTTAGCACTCTTACTGCCACAATGGCCGGATAACCTGCGAAGGATCCTGTACCAGC
GTCCAGTGATTGCAACAAGCAAACGGCTAGAAGATCTAGCATGCGCGCGAGGATTTATCAGCGTTTATCGCGCCACAGGA
CCATTGCCGCGCCAGTTAGCAGCAACAGCAGCGGCTTTTCGACCCGATAAAACAGCACAATGA

Upstream 100 bases:

>100_bases
TAGCAGCAACCATACCCATGGGTATTTAAATCGAGCCTCGCACGCCATCTTCACTCCATTAGGTATTGACAAACGCCATT
CAACGAATATCCGATCCATA

Downstream 100 bases:

>100_bases
CATCCAGCTTGCGGCAATGCCAAAGTACCCTAAGGAAGCCACCAATAATGAACGAGACCTCGCCCCCTACCCTGCGCCGT
ATTCCCTGGCTCTGGCTGCT

Product: uroporphyrinogen-III synthase

Products: uroporphyrinogen III; H2O

Alternate protein names: Uroporphyrinogen-III Synthase Protein

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MHTMTRPDQARTPWYLLSLRPANNHAALRRAVARYGGGLIALSPWRLKRLDSPETRSALASALTASTLVFTSPEAVRAAH
ALQTLRTSPGQVWLCVGASTARVLQQCGITRVLHPTQMNSEGLLTLLAQQPPTEVGLITAPGGRDLLQQKLLENGIRLHR
ADVYERQPLRLRTATLDTLQRNATRSLLALSSAEALALLLPQWPDNLRRILYQRPVIATSKRLEDLACARGFISVYRATG
PLPRQLAATAAAFRPDKTAQ

Sequences:

>Translated_260_residues
MHTMTRPDQARTPWYLLSLRPANNHAALRRAVARYGGGLIALSPWRLKRLDSPETRSALASALTASTLVFTSPEAVRAAH
ALQTLRTSPGQVWLCVGASTARVLQQCGITRVLHPTQMNSEGLLTLLAQQPPTEVGLITAPGGRDLLQQKLLENGIRLHR
ADVYERQPLRLRTATLDTLQRNATRSLLALSSAEALALLLPQWPDNLRRILYQRPVIATSKRLEDLACARGFISVYRATG
PLPRQLAATAAAFRPDKTAQ
>Mature_260_residues
MHTMTRPDQARTPWYLLSLRPANNHAALRRAVARYGGGLIALSPWRLKRLDSPETRSALASALTASTLVFTSPEAVRAAH
ALQTLRTSPGQVWLCVGASTARVLQQCGITRVLHPTQMNSEGLLTLLAQQPPTEVGLITAPGGRDLLQQKLLENGIRLHR
ADVYERQPLRLRTATLDTLQRNATRSLLALSSAEALALLLPQWPDNLRRILYQRPVIATSKRLEDLACARGFISVYRATG
PLPRQLAATAAAFRPDKTAQ

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 28568; Mature: 28568

Theoretical pI: Translated: 11.76; Mature: 11.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTMTRPDQARTPWYLLSLRPANNHAALRRAVARYGGGLIALSPWRLKRLDSPETRSALA
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCHHHHCCCCCHHHHHHH
SALTASTLVFTSPEAVRAAHALQTLRTSPGQVWLCVGASTARVLQQCGITRVLHPTQMNS
HHHHHHHEEEECCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCEEECCCCCCC
EGLLTLLAQQPPTEVGLITAPGGRDLLQQKLLENGIRLHRADVYERQPLRLRTATLDTLQ
CCCEEEEECCCCCCEEEEECCCCHHHHHHHHHHCCCEEEHHHHHCCCCCEEHHHHHHHHH
RNATRSLLALSSAEALALLLPQWPDNLRRILYQRPVIATSKRLEDLACARGFISVYRATG
HHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
PLPRQLAATAAAFRPDKTAQ
CCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MHTMTRPDQARTPWYLLSLRPANNHAALRRAVARYGGGLIALSPWRLKRLDSPETRSALA
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCHHHHCCCCCHHHHHHH
SALTASTLVFTSPEAVRAAHALQTLRTSPGQVWLCVGASTARVLQQCGITRVLHPTQMNS
HHHHHHHEEEECCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCEEECCCCCCC
EGLLTLLAQQPPTEVGLITAPGGRDLLQQKLLENGIRLHRADVYERQPLRLRTATLDTLQ
CCCEEEEECCCCCCEEEEECCCCHHHHHHHHHHCCCEEEHHHHHCCCCCEEHHHHHHHHH
RNATRSLLALSSAEALALLLPQWPDNLRRILYQRPVIATSKRLEDLACARGFISVYRATG
HHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
PLPRQLAATAAAFRPDKTAQ
CCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA