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The map label for this gene is tatD [H]

Identifier: 182681478

GI number: 182681478

Start: 1099577

End: 1100383

Strand: Direct

Name: tatD [H]

Synonym: XfasM23_0932

Alternate gene names: 182681478

Gene position: 1099577-1100383 (Clockwise)

Preceding gene: 182681477

Following gene: 182681479

Centisome position: 43.36

GC content: 51.43

Gene sequence:

>807_bases
ATGCAATTGATCGACATCGGCGCCAATCTTACCCACGAGTCATTTGATTACGATCGCGATGCAGTGTTACAGCGTGCCTA
TGAGGCAGGTGTAGTGCAGATGGTAGTGACCGGGAGCAATCGCACACATTCATCTCTTGCGTTGCTATTAGCGCAGCGTC
ATCCTGGCTTGCTATATGCCACTGCGGGGGTACATCCGCACTGTGCTGCTGAATATACCGATGAATGCGACGCAGAATTA
CGGATGCTGCATACACATAAGGAAGTAGTGGCAGTTGGCGAGTGCGGTTTGGATTACTTCCGAGATTTTTGTCCGTATCG
GACCCAACAACACGCGTTTGAGCGGCAATTGCAATTGGCTAGTGAGAATGGGAAGCCGTTGTTTTTACATCAACGTGAAG
CGCATAACGATTTTATGGCGATCATGCGTGGCTTTGAGGGTCGTCTCGGCCCGGTTGTTGTGCATTGCTTTACTGGCACG
CATGAGGAGCTGTTCGATTACCTAGATCATGATTGGTACATTGGTATTACTGGCTGGCTATGCGATGAGCGCCGTGGCAT
GCATCTGCGGGAATTGGTGCGCCATATTCCAGAAAAACGCTTGATGATCGAGACGGATGCACCTTATTTGCTTCCACGTA
CATTACGACCGTTGCCTAAGGATCGCCGTAATGAGCCGGCGTTTCTCCCTCATATCGTTACCGAACTAGCGCGCAACCGT
GGGGAAGATGTGGTTACCTGCGCCGCTCGTAGTACAGTCGCCGCACGTGAATTCTTCAGTCTTCCGGAAGCCGGTTCCGG
TTCATGA

Upstream 100 bases:

>100_bases
GTCTTAGAACAGCACGCTCCTACTTCACTATGGATAGCAGAAAGCACCTAAAGCATGCCGTACAATGCTGCGACTCTGTG
TTCAGGTTTTTATTTGTTAG

Downstream 100 bases:

>100_bases
GGATGAGCCTAGGCCACGTTCTCGAATACAACATTCAAGTTCTGCATCAGGTCGTCGGTTTTTATTCGCGTTTACTGAAT
GCTGCAATGTTCCTGTTCCT

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: DNase tatD [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MQLIDIGANLTHESFDYDRDAVLQRAYEAGVVQMVVTGSNRTHSSLALLLAQRHPGLLYATAGVHPHCAAEYTDECDAEL
RMLHTHKEVVAVGECGLDYFRDFCPYRTQQHAFERQLQLASENGKPLFLHQREAHNDFMAIMRGFEGRLGPVVVHCFTGT
HEELFDYLDHDWYIGITGWLCDERRGMHLRELVRHIPEKRLMIETDAPYLLPRTLRPLPKDRRNEPAFLPHIVTELARNR
GEDVVTCAARSTVAAREFFSLPEAGSGS

Sequences:

>Translated_268_residues
MQLIDIGANLTHESFDYDRDAVLQRAYEAGVVQMVVTGSNRTHSSLALLLAQRHPGLLYATAGVHPHCAAEYTDECDAEL
RMLHTHKEVVAVGECGLDYFRDFCPYRTQQHAFERQLQLASENGKPLFLHQREAHNDFMAIMRGFEGRLGPVVVHCFTGT
HEELFDYLDHDWYIGITGWLCDERRGMHLRELVRHIPEKRLMIETDAPYLLPRTLRPLPKDRRNEPAFLPHIVTELARNR
GEDVVTCAARSTVAAREFFSLPEAGSGS
>Mature_268_residues
MQLIDIGANLTHESFDYDRDAVLQRAYEAGVVQMVVTGSNRTHSSLALLLAQRHPGLLYATAGVHPHCAAEYTDECDAEL
RMLHTHKEVVAVGECGLDYFRDFCPYRTQQHAFERQLQLASENGKPLFLHQREAHNDFMAIMRGFEGRLGPVVVHCFTGT
HEELFDYLDHDWYIGITGWLCDERRGMHLRELVRHIPEKRLMIETDAPYLLPRTLRPLPKDRRNEPAFLPHIVTELARNR
GEDVVTCAARSTVAAREFFSLPEAGSGS

Specific function: Shows DNase activity [H]

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=278, Percent_Identity=35.9712230215827, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI225903439, Length=234, Percent_Identity=36.3247863247863, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI225903424, Length=188, Percent_Identity=38.2978723404255, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI110349730, Length=269, Percent_Identity=25.6505576208178, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI110349734, Length=269, Percent_Identity=26.0223048327138, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI226061853, Length=273, Percent_Identity=25.2747252747253, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=45.945945945946, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI87082439, Length=264, Percent_Identity=28.7878787878788, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787342, Length=246, Percent_Identity=32.1138211382114, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=38.0782918149466, Blast_Score=194, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI71980746, Length=270, Percent_Identity=27.037037037037, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=170, Percent_Identity=31.7647058823529, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24648690, Length=283, Percent_Identity=36.7491166077738, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI221330018, Length=229, Percent_Identity=38.4279475982533, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24586117, Length=213, Percent_Identity=38.0281690140845, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30522; Mature: 30522

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLIDIGANLTHESFDYDRDAVLQRAYEAGVVQMVVTGSNRTHSSLALLLAQRHPGLLYA
CEEEECCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEE
TAGVHPHCAAEYTDECDAELRMLHTHKEVVAVGECGLDYFRDFCPYRTQQHAFERQLQLA
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEHHCCHHHHHHHCCCCHHHHHHHHHHHHH
SENGKPLFLHQREAHNDFMAIMRGFEGRLGPVVVHCFTGTHEELFDYLDHDWYIGITGWL
CCCCCEEEEECHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHCCCEEEEEEEEE
CDERRGMHLRELVRHIPEKRLMIETDAPYLLPRTLRPLPKDRRNEPAFLPHIVTELARNR
ECCCCCCHHHHHHHHCCCCEEEEECCCCEECCHHHCCCCCCCCCCCCHHHHHHHHHHHCC
GEDVVTCAARSTVAAREFFSLPEAGSGS
CCCEEEEHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQLIDIGANLTHESFDYDRDAVLQRAYEAGVVQMVVTGSNRTHSSLALLLAQRHPGLLYA
CEEEECCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEE
TAGVHPHCAAEYTDECDAELRMLHTHKEVVAVGECGLDYFRDFCPYRTQQHAFERQLQLA
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEHHCCHHHHHHHCCCCHHHHHHHHHHHHH
SENGKPLFLHQREAHNDFMAIMRGFEGRLGPVVVHCFTGTHEELFDYLDHDWYIGITGWL
CCCCCEEEEECHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHCCCEEEEEEEEE
CDERRGMHLRELVRHIPEKRLMIETDAPYLLPRTLRPLPKDRRNEPAFLPHIVTELARNR
ECCCCCCHHHHHHHHCCCCEEEEECCCCEECCHHHCCCCCCCCCCCCHHHHHHHHHHHCC
GEDVVTCAARSTVAAREFFSLPEAGSGS
CCCEEEEHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584020; 9649434; 1379743; 9278503; 10747959 [H]