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The map label for this gene is sbcB

Identifier: 182681388

GI number: 182681388

Start: 989851

End: 991287

Strand: Reverse

Name: sbcB

Synonym: XfasM23_0837

Alternate gene names: 182681388

Gene position: 991287-989851 (Counterclockwise)

Preceding gene: 182681393

Following gene: 182681387

Centisome position: 39.09

GC content: 56.44

Gene sequence:

>1437_bases
ATGCCGCCCAGCTTTCTGTTCTACGACTTAGAAACTTTCGGTCAGGACCCCCGTCGTACCCGCATCGCACAGTTTGCCGC
AGTACGGACGGACACCCAATTAAACGTCATCGAAGAACCAATTAGTTTTCTCGTCAAACCCGCCGATGACCTGCTCCCCT
CACCCTACGCCACACTCATCACCGGGATCACTCCGCAACACGCACAACGTGAAGGCATCAATGAAGCAGCAGCCTTCGCG
CACATTGCAATGCAGATGACACAACCACACACCTGCTCACTCGGCTACAACACCCTACGTTTCGACGACGAATTCATCCG
CTACGGGCTATTCCGTCACTTCTACGACCCATACGAACGCGAGTGGCGCAACGGCAATTCACGGTGGGACCTGCTGGACA
TGCTGCGACTCATGCACGCAGTACGCCCAGAAGGCATCCACTGGCCAACACGTGAAGACGGTGCCCCCTCATTCAAACTC
GAACACCTAGCCCTTGCCAACCATGCACGCGAAGGCACAGCACACGAAGCATTATCAGATGTTTATGCCACCATCAGCAT
GGCGCGTAAATTCCGCGCCGCACAACCGCGCCTCTGGAATTACGCACTGCAACTGCGTGACAAACGCTTTTGCGCCAACC
TGCTCGACATCACCTCAATACAACCAGTACTGCATATCTCACAGCGCTATCCTGCCACACAACACTGCGCCGCCGCCGTG
CTGCCACTGACCACACACCCACACATCAACAACCGCATCATTGTTTTCGACTTGAACGGCGACATAGACACACTGCTGCG
CCTGTCTGCAGAAGACATCGCCGACCACCTGTACACCCCAGCCCTGGATTTACCCGAAGGCGAGCAACGTATCCCACTGA
AAGAAGTCCACCTCAACAAAGTACCGGCCCTGATCGCCTGGAACCACCTGCGTGCATCGGACTTCACACGCCTTGGCATG
GACCCGAGCATGCTAGAAACCAAAGCGGCACAACTGCGCGCATGCGGACCAGATTTGGCCGAAAAAGTCCGCAACGTTTT
CAGCCATACCTACAACACCGCCAACGACGCTGATGCTTCACTGTACGACGGCTTCCTCACCGAAGAGGACCGCCGCCTCC
TGCCACAACTACGCGCCTCCTCTCCTGACACCTTGGTAACGTTCGAACAGCGCCTTCGCGATCCACGTCTCATCGAACTG
CTGTTCCGCTACCGCGCACGTAATTTTCCAGAAACCCTCTCTTGCGACGAACAGACACGCTGGGACACCTATCGGCGACG
CCGTCTGACCACCGACACCGGCCTATCAGAACTCACCTTCGACCAATACCACGCCCAAATTGCGGAATTACGGATAACGC
ACTCCCAAGATGCCACCAAACAGACCCTATTGGACCAACTCGCCGCCTGGGGCTCCGAACTATCCCGCACCCTATGA

Upstream 100 bases:

>100_bases
TCATAATAATCCAATGTTATCTAACTGCCAGCTTCCTGATTACTAAGCGGCGTTGCAATACCATTACTCCACGCATTCCT
CTCCACAGATCCTACGCACG

Downstream 100 bases:

>100_bases
CCACATACTTCACCGACAACAGCTTCAAGTACTTGCAGGAACTGGCACACCACAATGACAAGATATGGTTTACCGCACAC
AAACCGCAGTACATCGAACA

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MPPSFLFYDLETFGQDPRRTRIAQFAAVRTDTQLNVIEEPISFLVKPADDLLPSPYATLITGITPQHAQREGINEAAAFA
HIAMQMTQPHTCSLGYNTLRFDDEFIRYGLFRHFYDPYEREWRNGNSRWDLLDMLRLMHAVRPEGIHWPTREDGAPSFKL
EHLALANHAREGTAHEALSDVYATISMARKFRAAQPRLWNYALQLRDKRFCANLLDITSIQPVLHISQRYPATQHCAAAV
LPLTTHPHINNRIIVFDLNGDIDTLLRLSAEDIADHLYTPALDLPEGEQRIPLKEVHLNKVPALIAWNHLRASDFTRLGM
DPSMLETKAAQLRACGPDLAEKVRNVFSHTYNTANDADASLYDGFLTEEDRRLLPQLRASSPDTLVTFEQRLRDPRLIEL
LFRYRARNFPETLSCDEQTRWDTYRRRRLTTDTGLSELTFDQYHAQIAELRITHSQDATKQTLLDQLAAWGSELSRTL

Sequences:

>Translated_478_residues
MPPSFLFYDLETFGQDPRRTRIAQFAAVRTDTQLNVIEEPISFLVKPADDLLPSPYATLITGITPQHAQREGINEAAAFA
HIAMQMTQPHTCSLGYNTLRFDDEFIRYGLFRHFYDPYEREWRNGNSRWDLLDMLRLMHAVRPEGIHWPTREDGAPSFKL
EHLALANHAREGTAHEALSDVYATISMARKFRAAQPRLWNYALQLRDKRFCANLLDITSIQPVLHISQRYPATQHCAAAV
LPLTTHPHINNRIIVFDLNGDIDTLLRLSAEDIADHLYTPALDLPEGEQRIPLKEVHLNKVPALIAWNHLRASDFTRLGM
DPSMLETKAAQLRACGPDLAEKVRNVFSHTYNTANDADASLYDGFLTEEDRRLLPQLRASSPDTLVTFEQRLRDPRLIEL
LFRYRARNFPETLSCDEQTRWDTYRRRRLTTDTGLSELTFDQYHAQIAELRITHSQDATKQTLLDQLAAWGSELSRTL
>Mature_477_residues
PPSFLFYDLETFGQDPRRTRIAQFAAVRTDTQLNVIEEPISFLVKPADDLLPSPYATLITGITPQHAQREGINEAAAFAH
IAMQMTQPHTCSLGYNTLRFDDEFIRYGLFRHFYDPYEREWRNGNSRWDLLDMLRLMHAVRPEGIHWPTREDGAPSFKLE
HLALANHAREGTAHEALSDVYATISMARKFRAAQPRLWNYALQLRDKRFCANLLDITSIQPVLHISQRYPATQHCAAAVL
PLTTHPHINNRIIVFDLNGDIDTLLRLSAEDIADHLYTPALDLPEGEQRIPLKEVHLNKVPALIAWNHLRASDFTRLGMD
PSMLETKAAQLRACGPDLAEKVRNVFSHTYNTANDADASLYDGFLTEEDRRLLPQLRASSPDTLVTFEQRLRDPRLIELL
FRYRARNFPETLSCDEQTRWDTYRRRRLTTDTGLSELTFDQYHAQIAELRITHSQDATKQTLLDQLAAWGSELSRTL

Specific function: Also functions as a DNA deoxyribophosphodiesterase that release deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=473, Percent_Identity=42.9175475687104, Blast_Score=372, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54954; Mature: 54823

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPSFLFYDLETFGQDPRRTRIAQFAAVRTDTQLNVIEEPISFLVKPADDLLPSPYATLI
CCCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHCCCCHHHHH
TGITPQHAQREGINEAAAFAHIAMQMTQPHTCSLGYNTLRFDDEFIRYGLFRHFYDPYER
CCCCCHHHHHCCCHHHHHHHHHHHHHCCCCEEECCCCEEECCHHHHHHHHHHHHCCHHHH
EWRNGNSRWDLLDMLRLMHAVRPEGIHWPTREDGAPSFKLEHLALANHAREGTAHEALSD
HHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHH
VYATISMARKFRAAQPRLWNYALQLRDKRFCANLLDITSIQPVLHISQRYPATQHCAAAV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LPLTTHPHINNRIIVFDLNGDIDTLLRLSAEDIADHLYTPALDLPEGEQRIPLKEVHLNK
EECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCC
VPALIAWNHLRASDFTRLGMDPSMLETKAAQLRACGPDLAEKVRNVFSHTYNTANDADAS
CCHHHEECCCCCCCHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHH
LYDGFLTEEDRRLLPQLRASSPDTLVTFEQRLRDPRLIELLFRYRARNFPETLSCDEQTR
HHCCCCCCHHHHHHHHHHCCCCCCEEHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHH
WDTYRRRRLTTDTGLSELTFDQYHAQIAELRITHSQDATKQTLLDQLAAWGSELSRTL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PPSFLFYDLETFGQDPRRTRIAQFAAVRTDTQLNVIEEPISFLVKPADDLLPSPYATLI
CCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHCCCCHHHHH
TGITPQHAQREGINEAAAFAHIAMQMTQPHTCSLGYNTLRFDDEFIRYGLFRHFYDPYER
CCCCCHHHHHCCCHHHHHHHHHHHHHCCCCEEECCCCEEECCHHHHHHHHHHHHCCHHHH
EWRNGNSRWDLLDMLRLMHAVRPEGIHWPTREDGAPSFKLEHLALANHAREGTAHEALSD
HHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHH
VYATISMARKFRAAQPRLWNYALQLRDKRFCANLLDITSIQPVLHISQRYPATQHCAAAV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LPLTTHPHINNRIIVFDLNGDIDTLLRLSAEDIADHLYTPALDLPEGEQRIPLKEVHLNK
EECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCC
VPALIAWNHLRASDFTRLGMDPSMLETKAAQLRACGPDLAEKVRNVFSHTYNTANDADAS
CCHHHEECCCCCCCHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHH
LYDGFLTEEDRRLLPQLRASSPDTLVTFEQRLRDPRLIELLFRYRARNFPETLSCDEQTR
HHCCCCCCHHHHHHHHHHCCCCCCEEHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHH
WDTYRRRRLTTDTGLSELTFDQYHAQIAELRITHSQDATKQTLLDQLAAWGSELSRTL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]