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The map label for this gene is bioC [H]

Identifier: 182681374

GI number: 182681374

Start: 968833

End: 969720

Strand: Reverse

Name: bioC [H]

Synonym: XfasM23_0822

Alternate gene names: 182681374

Gene position: 969720-968833 (Counterclockwise)

Preceding gene: 182681379

Following gene: 182681373

Centisome position: 38.24

GC content: 54.84

Gene sequence:

>888_bases
ATGAATGGTCTCTTTGATACTTATCATATTCGCCGCGCCTTTTCCCGCGCGGCCCACAGCTACGACACCAACGCCGTACT
CCAACACGAAGTTGAACAACGTCTACTCGAATCTCTGGACTATCTCGGCGACCGCATACCGCGCGTAATACTTGATGTAG
GAGCCGGCACCGGACGTGCCAGTATCGCAATGAAAAAACGCTGGCCTAAAGCACAAGTGATCGCACTCGATCAAGCAATG
CCGATGTTGCAAGAAGCACGGAAACGCAGTCACTGGTGGAACCCATTAGCCCTGATCTATGGCGATGCACGCACCCTGCC
AGTGGCAGACGCGAGTGTCGATGTCATCTTCAGCAACCTATGCCTACAGTGGATCGAAGATCTACCAACAGTATTCGCCG
GCTTCCGCCAAGCACTACGGCCCGGCGGCCTACTGCTGTGCTCCCTCTTCGGCCCAGATACCCTCATCGAATTGCGCCAA
GCATTTGCTCAGGCTGATGCAGTGCCGCACATCAGTCCTTTTCCATCAATGCCTCAGTGTGGCGACGCACTCGTATTGGC
TCATTTCCAAAACCCGGTACTAGACCGCGACCTATTCACCCTGACCTACGACGACCTATCAGCCCTGATGCGCTCGTTAC
GTGCGATCGGTGCAACCAACGCATTGCAAGAGCGCCGTACTACCCTGACAGGGCGTGGACGCTTCGCAGCCACCGCTGCC
GCCTATGAAACATTGCGCAACGCTGATAACAAACTCCCAAGCTCCTGGGAAGTCATCTACGCCTGCGCTTGGGCACCAAC
ATCGGAACCAATGACCAGAGAAAACAACCATGAAATTGCCAGCATCCCAATCAACTCCATTCCAATTCGCCGCCGCAATT
CCAGCTAA

Upstream 100 bases:

>100_bases
GCCTGAACACGTGCCTGGCATCAGATCAGTAGATGCAATGCCATCTACCCATCCACCGAATATCATCACAACTGGCTATG
CAACCGACAACGATTAACTG

Downstream 100 bases:

>100_bases
ATAGCACAACCACAAAACCCGCTCCTTACGCTACGATCACCCTTCTCATCAATACTGCGATACGTGCTCTCTACATGATC
AAATGGTCTTTGATAATCCT

Product: biotin biosynthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNGLFDTYHIRRAFSRAAHSYDTNAVLQHEVEQRLLESLDYLGDRIPRVILDVGAGTGRASIAMKKRWPKAQVIALDQAM
PMLQEARKRSHWWNPLALIYGDARTLPVADASVDVIFSNLCLQWIEDLPTVFAGFRQALRPGGLLLCSLFGPDTLIELRQ
AFAQADAVPHISPFPSMPQCGDALVLAHFQNPVLDRDLFTLTYDDLSALMRSLRAIGATNALQERRTTLTGRGRFAATAA
AYETLRNADNKLPSSWEVIYACAWAPTSEPMTRENNHEIASIPINSIPIRRRNSS

Sequences:

>Translated_295_residues
MNGLFDTYHIRRAFSRAAHSYDTNAVLQHEVEQRLLESLDYLGDRIPRVILDVGAGTGRASIAMKKRWPKAQVIALDQAM
PMLQEARKRSHWWNPLALIYGDARTLPVADASVDVIFSNLCLQWIEDLPTVFAGFRQALRPGGLLLCSLFGPDTLIELRQ
AFAQADAVPHISPFPSMPQCGDALVLAHFQNPVLDRDLFTLTYDDLSALMRSLRAIGATNALQERRTTLTGRGRFAATAA
AYETLRNADNKLPSSWEVIYACAWAPTSEPMTRENNHEIASIPINSIPIRRRNSS
>Mature_295_residues
MNGLFDTYHIRRAFSRAAHSYDTNAVLQHEVEQRLLESLDYLGDRIPRVILDVGAGTGRASIAMKKRWPKAQVIALDQAM
PMLQEARKRSHWWNPLALIYGDARTLPVADASVDVIFSNLCLQWIEDLPTVFAGFRQALRPGGLLLCSLFGPDTLIELRQ
AFAQADAVPHISPFPSMPQCGDALVLAHFQNPVLDRDLFTLTYDDLSALMRSLRAIGATNALQERRTTLTGRGRFAATAA
AYETLRNADNKLPSSWEVIYACAWAPTSEPMTRENNHEIASIPINSIPIRRRNSS

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Homo sapiens, GI40018642, Length=244, Percent_Identity=27.8688524590164, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI86792933, Length=151, Percent_Identity=32.4503311258278, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1786994, Length=215, Percent_Identity=33.0232558139535, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17535003, Length=228, Percent_Identity=25.4385964912281, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19922210, Length=272, Percent_Identity=29.0441176470588, Blast_Score=104, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 32926; Mature: 32926

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGLFDTYHIRRAFSRAAHSYDTNAVLQHEVEQRLLESLDYLGDRIPRVILDVGAGTGRA
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
SIAMKKRWPKAQVIALDQAMPMLQEARKRSHWWNPLALIYGDARTLPVADASVDVIFSNL
HHHHHHCCCCHHEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHH
CLQWIEDLPTVFAGFRQALRPGGLLLCSLFGPDTLIELRQAFAQADAVPHISPFPSMPQC
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GDALVLAHFQNPVLDRDLFTLTYDDLSALMRSLRAIGATNALQERRTTLTGRGRFAATAA
CCCEEEEECCCCCCCCHHHEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHH
AYETLRNADNKLPSSWEVIYACAWAPTSEPMTRENNHEIASIPINSIPIRRRNSS
HHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MNGLFDTYHIRRAFSRAAHSYDTNAVLQHEVEQRLLESLDYLGDRIPRVILDVGAGTGRA
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
SIAMKKRWPKAQVIALDQAMPMLQEARKRSHWWNPLALIYGDARTLPVADASVDVIFSNL
HHHHHHCCCCHHEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHH
CLQWIEDLPTVFAGFRQALRPGGLLLCSLFGPDTLIELRQAFAQADAVPHISPFPSMPQC
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GDALVLAHFQNPVLDRDLFTLTYDDLSALMRSLRAIGATNALQERRTTLTGRGRFAATAA
CCCEEEEECCCCCCCCHHHEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHH
AYETLRNADNKLPSSWEVIYACAWAPTSEPMTRENNHEIASIPINSIPIRRRNSS
HHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8250549 [H]