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The map label for this gene is sufC [H]

Identifier: 182681283

GI number: 182681283

Start: 857494

End: 858336

Strand: Reverse

Name: sufC [H]

Synonym: XfasM23_0728

Alternate gene names: 182681283

Gene position: 858336-857494 (Counterclockwise)

Preceding gene: 182681284

Following gene: 182681282

Centisome position: 33.85

GC content: 55.16

Gene sequence:

>843_bases
ATGACTATGCTGAAGATCGACACCCTCCATGCCTCCGTCGCCGGCAAGGAAATCCTCAAAGGCCTTTCCCTGGACATCGC
ACCTGGCCAAGTGCATGCCATCATGGGACCCAACGGTGCCGGAAAATCCACCCTAGGTCACATCCTTGCTGGCCGCGACG
GCTACGACGTCACCGCAGGTCAAGTGACCTTCGACAATCGCCCCCTGCTCACACTCCAACCAGAAGAACGCGCCGCCGCT
GGATTATTTCTAGCATTTCAATACCCCGTGGAAATTCCTGGAGTGAACAACACCTACTTCCTACGCTCAGCACTCAACGC
ACAACGCAAAGCACGCGGTGAAGAAGAACTTGACTCAATACAATTTCTCAAACGTGTCCGAGAAAAACTCGCGGTACTGC
ATCTGAAAGACGAACTGCTGCACCGCGGCGTCAACGAAGGATTTTCCGGCGGAGAGAAAAAGCGCAATGAAATCTTCCAA
CTCGCCGTCCTCGAACCCAAACTCGCCATCCTAGACGAAACCGACTCAGGCCTAGACATCGACGCACTGAAAACCGTCGC
CGATGGCGTCAACGCCCTGCGCTCACCGGAACGCGCATTCCTGGTCATCACCCACTACCAACGCCTGCTCGACTACATCA
AACCCGACGTTGTACACGTACTTGCCGAAGGTCGCATCGTAGAAACCGGCGGCCCTGAACTGGCACTGGAATTAGAACAA
CATGGCTACACCTGGTTGAAAAATCGTGTCATCCCCACCAGCGAAACAATGCCTCCCTCCCCCCATGATCCACACACCGA
CACACCCAGACTGAAGGCACCAACACCGCGGGAAAATGTCTGA

Upstream 100 bases:

>100_bases
GCTCTAAAACCCAAACACTCCATCCACTCCAACAACGCATCCAAACCGCCTCAGTCCCATAAAAACGTATCAGCGGACAC
AAGCTCATCCTATAGACATC

Downstream 100 bases:

>100_bases
TGAACCCCCTCCTTGACTCCCTGGCCGCCGCCTTCCAAAACGACGGTGACATCACCCGCCGCCAAGCACTGGAGGACGCA
CGTCGCGACGGCTTACCCGA

Product: FeS assembly ATPase SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MTMLKIDTLHASVAGKEILKGLSLDIAPGQVHAIMGPNGAGKSTLGHILAGRDGYDVTAGQVTFDNRPLLTLQPEERAAA
GLFLAFQYPVEIPGVNNTYFLRSALNAQRKARGEEELDSIQFLKRVREKLAVLHLKDELLHRGVNEGFSGGEKKRNEIFQ
LAVLEPKLAILDETDSGLDIDALKTVADGVNALRSPERAFLVITHYQRLLDYIKPDVVHVLAEGRIVETGGPELALELEQ
HGYTWLKNRVIPTSETMPPSPHDPHTDTPRLKAPTPRENV

Sequences:

>Translated_280_residues
MTMLKIDTLHASVAGKEILKGLSLDIAPGQVHAIMGPNGAGKSTLGHILAGRDGYDVTAGQVTFDNRPLLTLQPEERAAA
GLFLAFQYPVEIPGVNNTYFLRSALNAQRKARGEEELDSIQFLKRVREKLAVLHLKDELLHRGVNEGFSGGEKKRNEIFQ
LAVLEPKLAILDETDSGLDIDALKTVADGVNALRSPERAFLVITHYQRLLDYIKPDVVHVLAEGRIVETGGPELALELEQ
HGYTWLKNRVIPTSETMPPSPHDPHTDTPRLKAPTPRENV
>Mature_279_residues
TMLKIDTLHASVAGKEILKGLSLDIAPGQVHAIMGPNGAGKSTLGHILAGRDGYDVTAGQVTFDNRPLLTLQPEERAAAG
LFLAFQYPVEIPGVNNTYFLRSALNAQRKARGEEELDSIQFLKRVREKLAVLHLKDELLHRGVNEGFSGGEKKRNEIFQL
AVLEPKLAILDETDSGLDIDALKTVADGVNALRSPERAFLVITHYQRLLDYIKPDVVHVLAEGRIVETGGPELALELEQH
GYTWLKNRVIPTSETMPPSPHDPHTDTPRLKAPTPRENV

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI156105685, Length=255, Percent_Identity=28.6274509803922, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI42741659, Length=218, Percent_Identity=29.8165137614679, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787972, Length=247, Percent_Identity=62.3481781376518, Blast_Score=323, Evalue=7e-90,
Organism=Escherichia coli, GI1789891, Length=265, Percent_Identity=29.811320754717, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787370, Length=231, Percent_Identity=26.8398268398268, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082267, Length=181, Percent_Identity=32.0441988950276, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788225, Length=238, Percent_Identity=26.0504201680672, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787500, Length=268, Percent_Identity=27.9850746268657, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788761, Length=232, Percent_Identity=26.2931034482759, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87081709, Length=261, Percent_Identity=24.904214559387, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081791, Length=244, Percent_Identity=26.2295081967213, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789593, Length=251, Percent_Identity=23.9043824701195, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1790525, Length=195, Percent_Identity=30.7692307692308, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788506, Length=235, Percent_Identity=26.8085106382979, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787029, Length=239, Percent_Identity=23.8493723849372, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1786398, Length=223, Percent_Identity=27.3542600896861, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI87081834, Length=195, Percent_Identity=29.2307692307692, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17558664, Length=239, Percent_Identity=31.7991631799163, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI193209708, Length=221, Percent_Identity=28.9592760180996, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=227, Percent_Identity=27.3127753303965, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533592, Length=232, Percent_Identity=30.6034482758621, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI85726357, Length=221, Percent_Identity=28.9592760180996, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281363262, Length=223, Percent_Identity=32.2869955156951, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24653245, Length=223, Percent_Identity=32.2869955156951, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 30822; Mature: 30690

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMLKIDTLHASVAGKEILKGLSLDIAPGQVHAIMGPNGAGKSTLGHILAGRDGYDVTAG
CCEEEEEHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCCCHHHHHHHHCCCCCCEEECC
QVTFDNRPLLTLQPEERAAAGLFLAFQYPVEIPGVNNTYFLRSALNAQRKARGEEELDSI
EEEECCCCEEEECCHHHHHCEEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCHHHHHHH
QFLKRVREKLAVLHLKDELLHRGVNEGFSGGEKKRNEIFQLAVLEPKLAILDETDSGLDI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEEECCCEEEEECCCCCCCH
DALKTVADGVNALRSPERAFLVITHYQRLLDYIKPDVVHVLAEGRIVETGGPELALELEQ
HHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCHHHHHHHHCCEEEECCCCEEEEEEHH
HGYTWLKNRVIPTSETMPPSPHDPHTDTPRLKAPTPRENV
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TMLKIDTLHASVAGKEILKGLSLDIAPGQVHAIMGPNGAGKSTLGHILAGRDGYDVTAG
CEEEEEHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCCCHHHHHHHHCCCCCCEEECC
QVTFDNRPLLTLQPEERAAAGLFLAFQYPVEIPGVNNTYFLRSALNAQRKARGEEELDSI
EEEECCCCEEEECCHHHHHCEEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCHHHHHHH
QFLKRVREKLAVLHLKDELLHRGVNEGFSGGEKKRNEIFQLAVLEPKLAILDETDSGLDI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEEECCCEEEEECCCCCCCH
DALKTVADGVNALRSPERAFLVITHYQRLLDYIKPDVVHVLAEGRIVETGGPELALELEQ
HHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCHHHHHHHHCCEEEECCCCEEEEEEHH
HGYTWLKNRVIPTSETMPPSPHDPHTDTPRLKAPTPRENV
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]