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The map label for this gene is argD

Identifier: 182681241

GI number: 182681241

Start: 811485

End: 812720

Strand: Direct

Name: argD

Synonym: XfasM23_0686

Alternate gene names: 182681241

Gene position: 811485-812720 (Clockwise)

Preceding gene: 182681236

Following gene: 182681244

Centisome position: 32.0

GC content: 58.41

Gene sequence:

>1236_bases
ATGAGCGCTGTGTCTGAATCTGTGTTATCGCTGTCTCGCTATTATTTGCCGGTCTATCGTCCATGCCAGGTGGTGTTGGT
GCGTGGTCAAGGCAGCCGTGTATGGGATGAGCAGGGGCGCGATTATCTTGATCTGGCTGCTGGGATTGCGGTGTGTTGTT
TGGGGCATTGTGATCCGGATTTGGTCGCTGCTTTGGTGGAGCAGGCAGGTCGTCTGTGGCATACCAGCAATGTGTTTTAT
AGCGAGCCGTCGTTGCGCTTGGCGCAGGAGTTGGTGGATGTTTCACGGTTCGCTGAGAGGGTGTTTCTTTGCAGTTCCGG
GACTGAAGCCAACGAGGCGGCAATCAAGTTGGTGCGTAAGTGGGCTGCTGCGCAGGGGCGTTTACCGGAGCATCGTACGA
TTGTGACGTTCCGTGGCAGTTTCCACGGGCGTACTTTGGGTGCAGTGACGGCGACGGCGCAGCCTAAGTATCAGGAGGGC
TATGAGCCGTTGCCTGGGGGGTTCCGCTATGTCGATTTCAATCATATTGAGGCGTTGGAAGCGGCGATGGTCGGTGGTGA
TGTCGCTGCGGTGATGTTGGAGCCGATTCAAGGAGAGGGTGGGGTGATGCCGATAGCGCCAGGGTATTTGGCGCAGGTAC
GTGCGTTGTGTGATCGCTATGGGGCGCTGTTGGTATTGGATGAAATTCAGTGCGGCATGGGGCGTACTGGGACGTTGTTC
GCCTATTGGCAGGAAGAGGTGGTGCCGGACATTGTGACGTTGGCCAAGGGGCTTGGTGGAGGGTTTCCAATTGGTGCGAT
GTTGGCTGGTCCGAAGGTTGCTGAGGTGATGCAGTTCGGGGCGCATGGGACGACGTTTGGTGGCAATCCTATGGCTGCTG
CTGTGGCGCGGGTGGCGTTGCGTAAGTTGGCTTCGGTTGAGATTGCCGCCAATGTGCAGCGTCAGTCGGTCGCGCTACGC
GCTGGGTTGGAAGAGATCAGCGAGGCATTCGGTGGGGTGTTTACGCAGGTGCGCGGTCGCGGTCTGATGCTGGGCGCGGT
GTTGGCGCCGCTGTATGCAGGGCAAGCCAGTGCGATTCTTGAGGTGGCGGCTGAGCACGGTGTGTTGTTGTTACAGGCTG
GTCCTGACGTGCTGCGTTTTGTGCCGGCGCTGAATGTGAGTGATGAGGAGCTTGCCGATGGTTTGGTCCGGTTACGTGCG
GCGTTGGGGGATTATGTGTCGCGTTGCCGTGGCTGA

Upstream 100 bases:

>100_bases
TGGCGTCATTTGTGAGTCGAAAAGTAGGGGCATGTCGTGATCGTGTCTTATTGATTGAAATACACGAGAATGTAGCGTTC
ATATTATCGATAAGACGTCA

Downstream 100 bases:

>100_bases
GATGCCAAGGGGTGTAGGGGCTGTTTGATTGTGTTGGGGTTTCAGGGAGGATGTGTTGATCGGGGGGATTGTGTGATGTG
GGCAAGTTTTTCGGTGGGGT

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSAVSESVLSLSRYYLPVYRPCQVVLVRGQGSRVWDEQGRDYLDLAAGIAVCCLGHCDPDLVAALVEQAGRLWHTSNVFY
SEPSLRLAQELVDVSRFAERVFLCSSGTEANEAAIKLVRKWAAAQGRLPEHRTIVTFRGSFHGRTLGAVTATAQPKYQEG
YEPLPGGFRYVDFNHIEALEAAMVGGDVAAVMLEPIQGEGGVMPIAPGYLAQVRALCDRYGALLVLDEIQCGMGRTGTLF
AYWQEEVVPDIVTLAKGLGGGFPIGAMLAGPKVAEVMQFGAHGTTFGGNPMAAAVARVALRKLASVEIAANVQRQSVALR
AGLEEISEAFGGVFTQVRGRGLMLGAVLAPLYAGQASAILEVAAEHGVLLLQAGPDVLRFVPALNVSDEELADGLVRLRA
ALGDYVSRCRG

Sequences:

>Translated_411_residues
MSAVSESVLSLSRYYLPVYRPCQVVLVRGQGSRVWDEQGRDYLDLAAGIAVCCLGHCDPDLVAALVEQAGRLWHTSNVFY
SEPSLRLAQELVDVSRFAERVFLCSSGTEANEAAIKLVRKWAAAQGRLPEHRTIVTFRGSFHGRTLGAVTATAQPKYQEG
YEPLPGGFRYVDFNHIEALEAAMVGGDVAAVMLEPIQGEGGVMPIAPGYLAQVRALCDRYGALLVLDEIQCGMGRTGTLF
AYWQEEVVPDIVTLAKGLGGGFPIGAMLAGPKVAEVMQFGAHGTTFGGNPMAAAVARVALRKLASVEIAANVQRQSVALR
AGLEEISEAFGGVFTQVRGRGLMLGAVLAPLYAGQASAILEVAAEHGVLLLQAGPDVLRFVPALNVSDEELADGLVRLRA
ALGDYVSRCRG
>Mature_410_residues
SAVSESVLSLSRYYLPVYRPCQVVLVRGQGSRVWDEQGRDYLDLAAGIAVCCLGHCDPDLVAALVEQAGRLWHTSNVFYS
EPSLRLAQELVDVSRFAERVFLCSSGTEANEAAIKLVRKWAAAQGRLPEHRTIVTFRGSFHGRTLGAVTATAQPKYQEGY
EPLPGGFRYVDFNHIEALEAAMVGGDVAAVMLEPIQGEGGVMPIAPGYLAQVRALCDRYGALLVLDEIQCGMGRTGTLFA
YWQEEVVPDIVTLAKGLGGGFPIGAMLAGPKVAEVMQFGAHGTTFGGNPMAAAVARVALRKLASVEIAANVQRQSVALRA
GLEEISEAFGGVFTQVRGRGLMLGAVLAPLYAGQASAILEVAAEHGVLLLQAGPDVLRFVPALNVSDEELADGLVRLRAA
LGDYVSRCRG

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=379, Percent_Identity=35.8839050131926, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI284507298, Length=293, Percent_Identity=37.2013651877133, Blast_Score=191, Evalue=9e-49,
Organism=Homo sapiens, GI13994255, Length=437, Percent_Identity=29.0617848970252, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI37574042, Length=422, Percent_Identity=27.4881516587678, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI24119277, Length=429, Percent_Identity=28.9044289044289, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI226442705, Length=422, Percent_Identity=26.5402843601896, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI226442709, Length=392, Percent_Identity=27.0408163265306, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI1788044, Length=400, Percent_Identity=48.75, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1789759, Length=397, Percent_Identity=47.103274559194, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI145693181, Length=325, Percent_Identity=39.0769230769231, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789016, Length=397, Percent_Identity=34.2569269521411, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1787560, Length=410, Percent_Identity=31.4634146341463, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1786991, Length=341, Percent_Identity=33.1378299120235, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786349, Length=354, Percent_Identity=28.8135593220339, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25144271, Length=384, Percent_Identity=34.8958333333333, Blast_Score=241, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI32564660, Length=425, Percent_Identity=29.1764705882353, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI25144274, Length=275, Percent_Identity=35.6363636363636, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI71992977, Length=453, Percent_Identity=23.6203090507726, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17541228, Length=419, Percent_Identity=26.0143198090692, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71981843, Length=161, Percent_Identity=31.055900621118, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=408, Percent_Identity=36.2745098039216, Blast_Score=280, Evalue=4e-76,
Organism=Saccharomyces cerevisiae, GI6323470, Length=405, Percent_Identity=32.0987654320988, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6324386, Length=350, Percent_Identity=28.2857142857143, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=362, Percent_Identity=23.7569060773481, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357415, Length=393, Percent_Identity=35.3689567430025, Blast_Score=248, Evalue=7e-66,
Organism=Drosophila melanogaster, GI161085790, Length=436, Percent_Identity=30.5045871559633, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28574759, Length=421, Percent_Identity=31.1163895486936, Blast_Score=182, Evalue=5e-46,
Organism=Drosophila melanogaster, GI21356575, Length=427, Percent_Identity=27.1662763466042, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281366494, Length=429, Percent_Identity=23.7762237762238, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24667139, Length=429, Percent_Identity=23.7762237762238, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24667143, Length=429, Percent_Identity=23.7762237762238, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43773; Mature: 43642

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVSESVLSLSRYYLPVYRPCQVVLVRGQGSRVWDEQGRDYLDLAAGIAVCCLGHCDPD
CCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHCCCCHH
LVAALVEQAGRLWHTSNVFYSEPSLRLAQELVDVSRFAERVFLCSSGTEANEAAIKLVRK
HHHHHHHHHCCEEECCCEEECCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
WAAAQGRLPEHRTIVTFRGSFHGRTLGAVTATAQPKYQEGYEPLPGGFRYVDFNHIEALE
HHHHCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCHHCCCCCCCCCEEEEECHHHHHHH
AAMVGGDVAAVMLEPIQGEGGVMPIAPGYLAQVRALCDRYGALLVLDEIQCGMGRTGTLF
HHHHCCCEEEEEEECCCCCCCEECCCCHHHHHHHHHHHHCCCEEEEECHHCCCCCCCCEE
AYWQEEVVPDIVTLAKGLGGGFPIGAMLAGPKVAEVMQFGAHGTTFGGNPMAAAVARVAL
EEEHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
RKLASVEIAANVQRQSVALRAGLEEISEAFGGVFTQVRGRGLMLGAVLAPLYAGQASAIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHH
EVAAEHGVLLLQAGPDVLRFVPALNVSDEELADGLVRLRAALGDYVSRCRG
HHHHHCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAVSESVLSLSRYYLPVYRPCQVVLVRGQGSRVWDEQGRDYLDLAAGIAVCCLGHCDPD
CHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHCCCCHH
LVAALVEQAGRLWHTSNVFYSEPSLRLAQELVDVSRFAERVFLCSSGTEANEAAIKLVRK
HHHHHHHHHCCEEECCCEEECCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
WAAAQGRLPEHRTIVTFRGSFHGRTLGAVTATAQPKYQEGYEPLPGGFRYVDFNHIEALE
HHHHCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCHHCCCCCCCCCEEEEECHHHHHHH
AAMVGGDVAAVMLEPIQGEGGVMPIAPGYLAQVRALCDRYGALLVLDEIQCGMGRTGTLF
HHHHCCCEEEEEEECCCCCCCEECCCCHHHHHHHHHHHHCCCEEEEECHHCCCCCCCCEE
AYWQEEVVPDIVTLAKGLGGGFPIGAMLAGPKVAEVMQFGAHGTTFGGNPMAAAVARVAL
EEEHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
RKLASVEIAANVQRQSVALRAGLEEISEAFGGVFTQVRGRGLMLGAVLAPLYAGQASAIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHH
EVAAEHGVLLLQAGPDVLRFVPALNVSDEELADGLVRLRAALGDYVSRCRG
HHHHHCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]