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The map label for this gene is murA

Identifier: 182681232

GI number: 182681232

Start: 800189

End: 801466

Strand: Direct

Name: murA

Synonym: XfasM23_0677

Alternate gene names: 182681232

Gene position: 800189-801466 (Clockwise)

Preceding gene: 182681231

Following gene: 182681233

Centisome position: 31.56

GC content: 53.44

Gene sequence:

>1278_bases
ATGTCAAAAATTGTAGTTGCTGGTGGTACCCCGCTATATGGGGATGTTCGGATTTCCGGTGCCAAGAATGCTGTCCTTCC
TATTTTATGTGCCACGTTGCTCGCTGATGCGCCGGTGGAGATCAGCAACGTACCCTATCTGCATGACGTGATCACTATGA
TCAATTTGCTTCGTGAATTGGGTGCGGGTGTCACCATGAATGAAGGCATTGAGGCGAAAGGACGTTCGATTACGATTGAT
CCGCGCTGGGTACGTCAGCGCGTGGTGCCGTATGACTTGGTGAAGACCATGCGTGCTTCTGTGTTGCTGTTGGGTCCGTT
ATTGGCCTGCTATGGTGCCGCTGAAGTTGCACTTCCTGGGGGGTGTGCGATTGGTTCACGTCCGGTCGACCAGCACATCA
GAGGATTGCAATCACTTGGTGCGGAGATCACGGTTGAGAATGGCTACATCAAGGCTTCTGTCAGTCAGGGTCGATTGAAG
GGCGGTCGTTTCGTGTTCGACGTGGTGAGTGTGACAGGCACTGAGAACCTGTTGATGGCTGCAGCTGTGGCTCAGGGGAC
GAGCGTCATTGAGAATGCTGCGATGGAGCCGGAGGTTGTCGATTTAGCCGAGTGTTTGATCACTCTCGGTGCGCGTGTTG
AGGGTGCTGGTACCCCACGTATCGTGGTCGAAGGGGTGGAAAGGTTAAATAGCGGGCAGTATGCAGTGTTACCTGACCGC
ATTGAGACGGGTACTTTTTTGGTGGCTACAGCGATGACGGGGGGGCGGATTAGTATGCAGCAGGTGCGCCCGCAGACTCT
GGATGCGGTGCTGGGCAAACTGACCGAGGCCGGAGCGTGCATCGAAATAGGTGCAGATAGTATCCGTTTGGATATGCAGG
GGCGGCGCCCATGTTCTGTTAATCTGACAACTGCACCTTATCCTGGGTTTCCCACTGATATGCAGGCTCAATTTATGGCG
CTGAATTGTGTTGCAGAAGGTGTCGGTGTGATCAAAGAAACGATCTTTGAGAACCGTTTCATGCACGTTGATGAACTGTT
ACGGCTCGGCGCCAAAATTCAGATTGAGGGTCATACCGCGATTGTACAGGGTGTCGAGCGATTGAGCGGTGCACCGGTGA
TGGCGACTGACCTTCGCGCCTCGGCCTCATTGATTCTGGCTGGTTTGGTCGCGGAGGGGGAAACAATCATTGATCGCATT
TACCACCTGGATCGTGGTTACGAAAACATTGAGAGAAAACTCGGAGTGCTGGGTGCATCAATCCGGCGTATGACATGA

Upstream 100 bases:

>100_bases
GCTTAAAACGTTGACTCCTGATGAGGAGTGACAGCCTCGTTATTGGTTTGTGTTATTACTTTTTTCCTTCCACCTATCCG
TTGATGGTGCTGATTAATTC

Downstream 100 bases:

>100_bases
TTTTGCAGGGTCGCTTCAGTCGACGACGGAAGATCCTGGGTGCTGTCATGTTGGTGTTCCTATGTTGGTTGGGTTACACC
CGATACGTTGGTTTAGCGAT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MSKIVVAGGTPLYGDVRISGAKNAVLPILCATLLADAPVEISNVPYLHDVITMINLLRELGAGVTMNEGIEAKGRSITID
PRWVRQRVVPYDLVKTMRASVLLLGPLLACYGAAEVALPGGCAIGSRPVDQHIRGLQSLGAEITVENGYIKASVSQGRLK
GGRFVFDVVSVTGTENLLMAAAVAQGTSVIENAAMEPEVVDLAECLITLGARVEGAGTPRIVVEGVERLNSGQYAVLPDR
IETGTFLVATAMTGGRISMQQVRPQTLDAVLGKLTEAGACIEIGADSIRLDMQGRRPCSVNLTTAPYPGFPTDMQAQFMA
LNCVAEGVGVIKETIFENRFMHVDELLRLGAKIQIEGHTAIVQGVERLSGAPVMATDLRASASLILAGLVAEGETIIDRI
YHLDRGYENIERKLGVLGASIRRMT

Sequences:

>Translated_425_residues
MSKIVVAGGTPLYGDVRISGAKNAVLPILCATLLADAPVEISNVPYLHDVITMINLLRELGAGVTMNEGIEAKGRSITID
PRWVRQRVVPYDLVKTMRASVLLLGPLLACYGAAEVALPGGCAIGSRPVDQHIRGLQSLGAEITVENGYIKASVSQGRLK
GGRFVFDVVSVTGTENLLMAAAVAQGTSVIENAAMEPEVVDLAECLITLGARVEGAGTPRIVVEGVERLNSGQYAVLPDR
IETGTFLVATAMTGGRISMQQVRPQTLDAVLGKLTEAGACIEIGADSIRLDMQGRRPCSVNLTTAPYPGFPTDMQAQFMA
LNCVAEGVGVIKETIFENRFMHVDELLRLGAKIQIEGHTAIVQGVERLSGAPVMATDLRASASLILAGLVAEGETIIDRI
YHLDRGYENIERKLGVLGASIRRMT
>Mature_424_residues
SKIVVAGGTPLYGDVRISGAKNAVLPILCATLLADAPVEISNVPYLHDVITMINLLRELGAGVTMNEGIEAKGRSITIDP
RWVRQRVVPYDLVKTMRASVLLLGPLLACYGAAEVALPGGCAIGSRPVDQHIRGLQSLGAEITVENGYIKASVSQGRLKG
GRFVFDVVSVTGTENLLMAAAVAQGTSVIENAAMEPEVVDLAECLITLGARVEGAGTPRIVVEGVERLNSGQYAVLPDRI
ETGTFLVATAMTGGRISMQQVRPQTLDAVLGKLTEAGACIEIGADSIRLDMQGRRPCSVNLTTAPYPGFPTDMQAQFMAL
NCVAEGVGVIKETIFENRFMHVDELLRLGAKIQIEGHTAIVQGVERLSGAPVMATDLRASASLILAGLVAEGETIIDRIY
HLDRGYENIERKLGVLGASIRRMT

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=424, Percent_Identity=62.2641509433962, Blast_Score=505, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_XYLF2 (B2I9M4)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829392.1
- ProteinModelPortal:   B2I9M4
- SMR:   B2I9M4
- GeneID:   6203655
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0677
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45154; Mature: 45023

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: ACT_SITE 122-122

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIVVAGGTPLYGDVRISGAKNAVLPILCATLLADAPVEISNVPYLHDVITMINLLREL
CCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
GAGVTMNEGIEAKGRSITIDPRWVRQRVVPYDLVKTMRASVLLLGPLLACYGAAEVALPG
CCCCEECCCCCCCCCEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCC
GCAIGSRPVDQHIRGLQSLGAEITVENGYIKASVSQGRLKGGRFVFDVVSVTGTENLLMA
CCCCCCCCHHHHHHHHHHCCCEEEEECCEEEEECCCCCCCCCEEEEEEEEECCCHHHHHH
AAVAQGTSVIENAAMEPEVVDLAECLITLGARVEGAGTPRIVVEGVERLNSGQYAVLPDR
HHHHHCHHHHHHCCCCCHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHCCCCCEEEECCC
IETGTFLVATAMTGGRISMQQVRPQTLDAVLGKLTEAGACIEIGADSIRLDMQGRRPCSV
CCCCCEEEEEECCCCCEEHHHCCHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCEE
NLTTAPYPGFPTDMQAQFMALNCVAEGVGVIKETIFENRFMHVDELLRLGAKIQIEGHTA
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCCHH
IVQGVERLSGAPVMATDLRASASLILAGLVAEGETIIDRIYHLDRGYENIERKLGVLGAS
HHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
IRRMT
HHCCC
>Mature Secondary Structure 
SKIVVAGGTPLYGDVRISGAKNAVLPILCATLLADAPVEISNVPYLHDVITMINLLREL
CEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
GAGVTMNEGIEAKGRSITIDPRWVRQRVVPYDLVKTMRASVLLLGPLLACYGAAEVALPG
CCCCEECCCCCCCCCEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCC
GCAIGSRPVDQHIRGLQSLGAEITVENGYIKASVSQGRLKGGRFVFDVVSVTGTENLLMA
CCCCCCCCHHHHHHHHHHCCCEEEEECCEEEEECCCCCCCCCEEEEEEEEECCCHHHHHH
AAVAQGTSVIENAAMEPEVVDLAECLITLGARVEGAGTPRIVVEGVERLNSGQYAVLPDR
HHHHHCHHHHHHCCCCCHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHCCCCCEEEECCC
IETGTFLVATAMTGGRISMQQVRPQTLDAVLGKLTEAGACIEIGADSIRLDMQGRRPCSV
CCCCCEEEEEECCCCCEEHHHCCHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCEE
NLTTAPYPGFPTDMQAQFMALNCVAEGVGVIKETIFENRFMHVDELLRLGAKIQIEGHTA
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCCHH
IVQGVERLSGAPVMATDLRASASLILAGLVAEGETIIDRIYHLDRGYENIERKLGVLGAS
HHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
IRRMT
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA