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The map label for this gene is kdsC [H]

Identifier: 182681229

GI number: 182681229

Start: 798263

End: 798811

Strand: Reverse

Name: kdsC [H]

Synonym: XfasM23_0674

Alternate gene names: 182681229

Gene position: 798811-798263 (Counterclockwise)

Preceding gene: 182681230

Following gene: 182681228

Centisome position: 31.5

GC content: 55.19

Gene sequence:

>549_bases
ATGCCTTATTCCCCATTAAATACCCTGCCTGCCGATGTCATTCAACGTGCAAAATGCATCCGCTTAGCATGCTTTGACGT
GGATGGCACACTCACTGACGGTCGTCTGTACTACGACCACGTCGGCCATGAAAGTAAGGCATTCCATGTGCTCGACGGTC
AGGGTCTCAAACAATTAGAACACTGCGGCATCCGCGTCACCCTAATCACCGCACTAGCCAGCTTAGCCGCTAAAAAACGC
GCCGAAGACCTAGGACTCCCGATAAAAATCGGCGTGCAAGACAAACGTTTAGCGGTACAAACACTGGCAATGGAATCAGG
AATCGGTATGGACGCCGTGTTATTCATGGGCGATGACCTAGTCGATTTACCTGCCCTGCTCACAGTCGGTCTACCAGTGG
CCCCGGCTAACGCACATCCGTGGATCGCAGAGAGGGTCGCTTGGCAGACCCGCGCCCGAGGAGGCGAGGGGGCCGCCCGG
GAAGTCTGCGATGTGCTCCTGGCGGCACAAGACAAAGTCGACGCACTATTGCGAAAATTCACCCCATGA

Upstream 100 bases:

>100_bases
ATGGTTTGATTGTGGTCGATCCGCAACAGCGTGCGGTAGGCGCCCTGAACATTCACGACCTGCTGCACGCCAAAATTGTT
TAATCCTCTGAAAAATACCA

Downstream 100 bases:

>100_bases
GTTGGCGCAGTATTCTCAACATCATGCTATTGCTCGCTGCGATTGTCAGCGGTTGGTCAGCGTGGCATCAACGCAAACAC
ACCCAAGCCACACCGCTACG

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MPYSPLNTLPADVIQRAKCIRLACFDVDGTLTDGRLYYDHVGHESKAFHVLDGQGLKQLEHCGIRVTLITALASLAAKKR
AEDLGLPIKIGVQDKRLAVQTLAMESGIGMDAVLFMGDDLVDLPALLTVGLPVAPANAHPWIAERVAWQTRARGGEGAAR
EVCDVLLAAQDKVDALLRKFTP

Sequences:

>Translated_182_residues
MPYSPLNTLPADVIQRAKCIRLACFDVDGTLTDGRLYYDHVGHESKAFHVLDGQGLKQLEHCGIRVTLITALASLAAKKR
AEDLGLPIKIGVQDKRLAVQTLAMESGIGMDAVLFMGDDLVDLPALLTVGLPVAPANAHPWIAERVAWQTRARGGEGAAR
EVCDVLLAAQDKVDALLRKFTP
>Mature_181_residues
PYSPLNTLPADVIQRAKCIRLACFDVDGTLTDGRLYYDHVGHESKAFHVLDGQGLKQLEHCGIRVTLITALASLAAKKRA
EDLGLPIKIGVQDKRLAVQTLAMESGIGMDAVLFMGDDLVDLPALLTVGLPVAPANAHPWIAERVAWQTRARGGEGAARE
VCDVLLAAQDKVDALLRKFTP

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=165, Percent_Identity=29.0909090909091, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI2367202, Length=173, Percent_Identity=42.1965317919075, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 19634; Mature: 19503

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYSPLNTLPADVIQRAKCIRLACFDVDGTLTDGRLYYDHVGHESKAFHVLDGQGLKQLE
CCCCCCCCCHHHHHHHHHHHEEEEECCCCCEECCEEEEECCCCCCCEEEEECCCCHHHHH
HCGIRVTLITALASLAAKKRAEDLGLPIKIGVQDKRLAVQTLAMESGIGMDAVLFMGDDL
HCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCH
VDLPALLTVGLPVAPANAHPWIAERVAWQTRARGGEGAAREVCDVLLAAQDKVDALLRKF
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
TP
CC
>Mature Secondary Structure 
PYSPLNTLPADVIQRAKCIRLACFDVDGTLTDGRLYYDHVGHESKAFHVLDGQGLKQLE
CCCCCCCCHHHHHHHHHHHEEEEECCCCCEECCEEEEECCCCCCCEEEEECCCCHHHHH
HCGIRVTLITALASLAAKKRAEDLGLPIKIGVQDKRLAVQTLAMESGIGMDAVLFMGDDL
HCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCH
VDLPALLTVGLPVAPANAHPWIAERVAWQTRARGGEGAAREVCDVLLAAQDKVDALLRKF
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
TP
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]