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The map label for this gene is hprK

Identifier: 182681223

GI number: 182681223

Start: 793413

End: 794363

Strand: Reverse

Name: hprK

Synonym: XfasM23_0668

Alternate gene names: 182681223

Gene position: 794363-793413 (Counterclockwise)

Preceding gene: 182681224

Following gene: 182681222

Centisome position: 31.33

GC content: 53.31

Gene sequence:

>951_bases
ATGAATACCAGCATCACCGCCCGCGAACTGTTCGACTTACAACGCGACCGCCTCTCTCTACGCTGGATTGCGGGACAACA
GGGCGAACACCGTCAGATTGACTCCGGTGATACCCGCGCCCGACGTCCCTCACTCGCCGGCTACCTGAATACCATCTACC
CAAACAAAGTGCAGATCCTCGGTACCGAAGAACTGACTTGGTTGGATTCTCTGGAACCAAACAAACGCAAAGAAACCATT
GAGAAGATCATCCAATTCCAACCGCTCACCCTGGTCATCAGCAAGAATCAATCCTGTCCGGAAGACATGCGGACAGCAGC
AGACAACAGCCAGATTCCCTTATGGGTCTCTCCCAAGCGAGGCCACGAGCTTCTCAACCATCTTTCCTACCACCTCGCAC
GCATATTGGCGCCACGCGCCACGCTACACGGGGTATTCATGGAAATCTATTCAATTGGCGTACTCATCACTGGGGAAGCT
GGCTCAGGCAAGAGCGAACTAGCGCTGGAACTCCTCAGTCGTGGTCATCGTCTCGTTGCTGACGATGCTCCAGAATTCAC
TCAGATCGCTCCGGACGTACTTGACGGCACCTGCCCTGAAATACTCCAAGACTTACTAGAAGTACGCGGCCTAGGCGTAT
TGAACGTACGCCACATGTTCGGCGATACCGCAATAAAGAAGAACAAATATCTACGCCTGATCGTACACTTAACCAAGCCA
ATAACCGAACCCACACCTTCCGGCTACGAACGCCTCACAGGGGATTCAGGCACACGCCACGTACTAGACTTGGATGTTCC
ATTAATTACTTTGCCAGTGATGCCTGGTCGCAACCTCGCAGTATTGACGGAAGCAGCCACACGCCTACACATTCTGCGTA
CCAAAGGCATCGACCCAGCAACAATGTTTATTGCCCGGCACAGCAACCTGCTAGAACGGCGTCCCCCATGA

Upstream 100 bases:

>100_bases
CTGCTGCGTTGGCCTCACTCAATAGTAGACTTACTATTCAACGCAGCAGATGAAATCCCCAAACTGCTACTTTCTATACC
AAGCCCGCAAAAAACGCTGA

Downstream 100 bases:

>100_bases
AACCGCCAGAACATAGCCTCATTATCATCAGCGGCCTATCTGGCTCTGGCAAATCCGTCGCCCTAAAGACCTTTGAAGAC
CTTGATTATTACTGCTCAGA

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNTSITARELFDLQRDRLSLRWIAGQQGEHRQIDSGDTRARRPSLAGYLNTIYPNKVQILGTEELTWLDSLEPNKRKETI
EKIIQFQPLTLVISKNQSCPEDMRTAADNSQIPLWVSPKRGHELLNHLSYHLARILAPRATLHGVFMEIYSIGVLITGEA
GSGKSELALELLSRGHRLVADDAPEFTQIAPDVLDGTCPEILQDLLEVRGLGVLNVRHMFGDTAIKKNKYLRLIVHLTKP
ITEPTPSGYERLTGDSGTRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPATMFIARHSNLLERRPP

Sequences:

>Translated_316_residues
MNTSITARELFDLQRDRLSLRWIAGQQGEHRQIDSGDTRARRPSLAGYLNTIYPNKVQILGTEELTWLDSLEPNKRKETI
EKIIQFQPLTLVISKNQSCPEDMRTAADNSQIPLWVSPKRGHELLNHLSYHLARILAPRATLHGVFMEIYSIGVLITGEA
GSGKSELALELLSRGHRLVADDAPEFTQIAPDVLDGTCPEILQDLLEVRGLGVLNVRHMFGDTAIKKNKYLRLIVHLTKP
ITEPTPSGYERLTGDSGTRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPATMFIARHSNLLERRPP
>Mature_316_residues
MNTSITARELFDLQRDRLSLRWIAGQQGEHRQIDSGDTRARRPSLAGYLNTIYPNKVQILGTEELTWLDSLEPNKRKETI
EKIIQFQPLTLVISKNQSCPEDMRTAADNSQIPLWVSPKRGHELLNHLSYHLARILAPRATLHGVFMEIYSIGVLITGEA
GSGKSELALELLSRGHRLVADDAPEFTQIAPDVLDGTCPEILQDLLEVRGLGVLNVRHMFGDTAIKKNKYLRLIVHLTKP
ITEPTPSGYERLTGDSGTRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPATMFIARHSNLLERRPP

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_XYLF2 (B2I9L5)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829383.1
- ProteinModelPortal:   B2I9L5
- GeneID:   6203021
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0668
- HOGENOM:   HBG566466
- OMA:   IHGVLVD
- ProtClustDB:   PRK05428
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 35394; Mature: 35394

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: ACT_SITE 143-143 ACT_SITE 164-164 ACT_SITE 182-182 ACT_SITE 251-251

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSITARELFDLQRDRLSLRWIAGQQGEHRQIDSGDTRARRPSLAGYLNTIYPNKVQIL
CCCCCCHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEE
GTEELTWLDSLEPNKRKETIEKIIQFQPLTLVISKNQSCPEDMRTAADNSQIPLWVSPKR
ECCCCHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCCCCEEEECCHH
GHELLNHLSYHLARILAPRATLHGVFMEIYSIGVLITGEAGSGKSELALELLSRGHRLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCEEEC
DDAPEFTQIAPDVLDGTCPEILQDLLEVRGLGVLNVRHMFGDTAIKKNKYLRLIVHLTKP
CCCCHHHHHCHHHHCCCHHHHHHHHHHHCCCCEEEHHHHHCCHHHCCCCCEEEEEEECCC
ITEPTPSGYERLTGDSGTRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPA
CCCCCCCCHHHHCCCCCCCEEEEECCCEEEEECCCCCCEEEEHHHHHHEEEEECCCCCHH
TMFIARHSNLLERRPP
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTSITARELFDLQRDRLSLRWIAGQQGEHRQIDSGDTRARRPSLAGYLNTIYPNKVQIL
CCCCCCHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEE
GTEELTWLDSLEPNKRKETIEKIIQFQPLTLVISKNQSCPEDMRTAADNSQIPLWVSPKR
ECCCCHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCCCCEEEECCHH
GHELLNHLSYHLARILAPRATLHGVFMEIYSIGVLITGEAGSGKSELALELLSRGHRLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCEEEC
DDAPEFTQIAPDVLDGTCPEILQDLLEVRGLGVLNVRHMFGDTAIKKNKYLRLIVHLTKP
CCCCHHHHHCHHHHCCCHHHHHHHHHHHCCCCEEEHHHHHCCHHHCCCCCEEEEEEECCC
ITEPTPSGYERLTGDSGTRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPA
CCCCCCCCHHHHCCCCCCCEEEEECCCEEEEECCCCCCEEEEHHHHHHEEEEECCCCCHH
TMFIARHSNLLERRPP
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA