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The map label for this gene is pdxH [H]

Identifier: 182681170

GI number: 182681170

Start: 724294

End: 724893

Strand: Direct

Name: pdxH [H]

Synonym: XfasM23_0612

Alternate gene names: 182681170

Gene position: 724294-724893 (Clockwise)

Preceding gene: 182681163

Following gene: 182681172

Centisome position: 28.56

GC content: 55.17

Gene sequence:

>600_bases
ATGCTCAATTTGTATGCTGAAGCCTTGTCCACGTTCTCGTTGTTGTTTGAAGAAGCCAAAAGCAGCAGCGAGATTGAGCC
TGATGCAATGATGTTGGCCACGGCTTCGTTAGAGGGTCATCCGAGTGTGCGTACGGTCTTGTTGAAGAAGTTCGACGCGC
GTGGTTTTGTTTTCTATAGTCATCTTGATAGCCCCAAGGGGCGCGATTTGCAGGCCAATCCGCAGGCTGCTTTGTTGTTT
TTGTGGCGTTCTCTGCGTGAGGCTGGGGTGCAGGTGCGTATTGAGGGGAGGGTGCAGCAGGTCCTTGCCGAGGAGGCGGA
TGCCTATTTCGCTTCGCGTCCGCGTCAGAGTCAAATTGGTGCATGGGCTTCGATGCAGTCGTGTCCCTTGGGGTCGCCTG
AGGAGTTTCAGGCACGTTTGGCGGAGGTGAAAGCGATGTTTGAGGGACGTGATGTGCCACGCCCGGAAGAGTGGGTGGGG
TTCCGTGTGGTGCCTCAAGTGTTCGAGTTTTGGTATGGGGCCAGCTTTCGGTTGCATGAGCGCTGGCGTTACCAGGCGGA
TGCTGCTGGCTATTGGCGTAAGTCTTTGTTGTATCCCTGA

Upstream 100 bases:

>100_bases
TTGCACTGTGTGGGTTTGAATGGCTGTCTTGATTTGCCTATAGGCGGGGCGATAGGGGTGCGACCACAATAGGGTGATCT
TTCCATGTCTGTTTCAATCT

Downstream 100 bases:

>100_bases
TGGGGATTGTCAGAATGGATGGCAGGATGTTGTGTTGTAGCAGTGTGTGGAGGTGCTGTGTGTGTCCCGTGTCATGGCAC
TTTGGGCAGTGGATGCTCAG

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MLNLYAEALSTFSLLFEEAKSSSEIEPDAMMLATASLEGHPSVRTVLLKKFDARGFVFYSHLDSPKGRDLQANPQAALLF
LWRSLREAGVQVRIEGRVQQVLAEEADAYFASRPRQSQIGAWASMQSCPLGSPEEFQARLAEVKAMFEGRDVPRPEEWVG
FRVVPQVFEFWYGASFRLHERWRYQADAAGYWRKSLLYP

Sequences:

>Translated_199_residues
MLNLYAEALSTFSLLFEEAKSSSEIEPDAMMLATASLEGHPSVRTVLLKKFDARGFVFYSHLDSPKGRDLQANPQAALLF
LWRSLREAGVQVRIEGRVQQVLAEEADAYFASRPRQSQIGAWASMQSCPLGSPEEFQARLAEVKAMFEGRDVPRPEEWVG
FRVVPQVFEFWYGASFRLHERWRYQADAAGYWRKSLLYP
>Mature_199_residues
MLNLYAEALSTFSLLFEEAKSSSEIEPDAMMLATASLEGHPSVRTVLLKKFDARGFVFYSHLDSPKGRDLQANPQAALLF
LWRSLREAGVQVRIEGRVQQVLAEEADAYFASRPRQSQIGAWASMQSCPLGSPEEFQARLAEVKAMFEGRDVPRPEEWVG
FRVVPQVFEFWYGASFRLHERWRYQADAAGYWRKSLLYP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=176, Percent_Identity=42.0454545454545, Blast_Score=143, Evalue=8e-35,
Organism=Escherichia coli, GI1787926, Length=197, Percent_Identity=38.0710659898477, Blast_Score=136, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17553712, Length=191, Percent_Identity=36.1256544502618, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319509, Length=186, Percent_Identity=39.247311827957, Blast_Score=125, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24644901, Length=171, Percent_Identity=42.1052631578947, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI45551845, Length=171, Percent_Identity=42.1052631578947, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24644903, Length=165, Percent_Identity=26.0606060606061, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 22743; Mature: 22743

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNLYAEALSTFSLLFEEAKSSSEIEPDAMMLATASLEGHPSVRTVLLKKFDARGFVFYS
CCCHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEECCCCCCHHHHHHHHHHCCCCEEEEE
HLDSPKGRDLQANPQAALLFLWRSLREAGVQVRIEGRVQQVLAEEADAYFASRPRQSQIG
ECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHH
AWASMQSCPLGSPEEFQARLAEVKAMFEGRDVPRPEEWVGFRVVPQVFEFWYGASFRLHE
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHCCCEEEHH
RWRYQADAAGYWRKSLLYP
HHHCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MLNLYAEALSTFSLLFEEAKSSSEIEPDAMMLATASLEGHPSVRTVLLKKFDARGFVFYS
CCCHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEECCCCCCHHHHHHHHHHCCCCEEEEE
HLDSPKGRDLQANPQAALLFLWRSLREAGVQVRIEGRVQQVLAEEADAYFASRPRQSQIG
ECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHH
AWASMQSCPLGSPEEFQARLAEVKAMFEGRDVPRPEEWVGFRVVPQVFEFWYGASFRLHE
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHCCCEEEHH
RWRYQADAAGYWRKSLLYP
HHHCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]