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The map label for this gene is yfjP [H]

Identifier: 182681159

GI number: 182681159

Start: 711182

End: 711862

Strand: Direct

Name: yfjP [H]

Synonym: XfasM23_0601

Alternate gene names: 182681159

Gene position: 711182-711862 (Clockwise)

Preceding gene: 182681158

Following gene: 182681163

Centisome position: 28.05

GC content: 54.48

Gene sequence:

>681_bases
ATGGCTTGGTACCCACGTGGTTTCGATGTTATGGCAGCCTATGATTATCTTTACCACTGCGACCCTGGGTTGTCGGGGTG
GATGCAGCGTCTGGGTCCGTTGCCAGCTCTGCGGCGCTGGCGTCAGCCGTTCAACGTAGTTGATGCTCTGGCCAGAGCGA
TCCTGTTCCAGCAACTGAGTGGTAAAGCGGCTTCAACCATTGTTGCTCGTATTGAGGCTGTGATTGGTAGCACCTGCTTA
TATGCCGAAACACTTGCGTGTATTGATGATGCGTGCTTGCGTGCCTGCGGTGTCTCCAGCAACAAGATTCTGGCGTTACG
CGATCTGACGCGGCGTGAAGTGGCAGGCGAGCTTCCCAGTGTGTGGCAGATGGGGTCAATGCACCATAACACCATCGTTG
AAAAATTAATTCCGATTCGTGGTATTGGTCGTTGGACTGTGGAGATGATGCTGATATTCCGTCTTGGCCGTCCCGATGTG
CTGCCGGTGGATGATTTAGGGGTACGCAAGGGTATCCAGCGTGTGGATAGCCTTGCTTTCGTCCCGACTCCGAAGGCGCT
ATGTACCCGCGGCGAATGCTGGGCACCTTACCGCACCTATGCCGGGTTATATCTATGGCGGATTGCCGATTTCCATGAAG
GAGAAAGAGCGGTGATCTCTGATCGTTCGCAGGACGAGTAG

Upstream 100 bases:

>100_bases
TGTTGGCAGGTGCGTTGTTGCAGGTCTCTCAGTGCTGCTGGATCGTGATGATGACAGGCAAGATACTGCTGGTTATTGAT
ACATGGAGGCGCTGAAGTGC

Downstream 100 bases:

>100_bases
TGAGCGGCCAGCCTTCGATTCTAGACACTAATCAGCAGTGGAATGCGTCCTTGGGTAATCAAATTAGGGCAGGAATGGTT
TCGCGTTTAAATGCTTCCAT

Product: HhH-GPD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MAWYPRGFDVMAAYDYLYHCDPGLSGWMQRLGPLPALRRWRQPFNVVDALARAILFQQLSGKAASTIVARIEAVIGSTCL
YAETLACIDDACLRACGVSSNKILALRDLTRREVAGELPSVWQMGSMHHNTIVEKLIPIRGIGRWTVEMMLIFRLGRPDV
LPVDDLGVRKGIQRVDSLAFVPTPKALCTRGECWAPYRTYAGLYLWRIADFHEGERAVISDRSQDE

Sequences:

>Translated_226_residues
MAWYPRGFDVMAAYDYLYHCDPGLSGWMQRLGPLPALRRWRQPFNVVDALARAILFQQLSGKAASTIVARIEAVIGSTCL
YAETLACIDDACLRACGVSSNKILALRDLTRREVAGELPSVWQMGSMHHNTIVEKLIPIRGIGRWTVEMMLIFRLGRPDV
LPVDDLGVRKGIQRVDSLAFVPTPKALCTRGECWAPYRTYAGLYLWRIADFHEGERAVISDRSQDE
>Mature_225_residues
AWYPRGFDVMAAYDYLYHCDPGLSGWMQRLGPLPALRRWRQPFNVVDALARAILFQQLSGKAASTIVARIEAVIGSTCLY
AETLACIDDACLRACGVSSNKILALRDLTRREVAGELPSVWQMGSMHHNTIVEKLIPIRGIGRWTVEMMLIFRLGRPDVL
PVDDLGVRKGIQRVDSLAFVPTPKALCTRGECWAPYRTYAGLYLWRIADFHEGERAVISDRSQDE

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 25442; Mature: 25311

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWYPRGFDVMAAYDYLYHCDPGLSGWMQRLGPLPALRRWRQPFNVVDALARAILFQQLS
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHC
GKAASTIVARIEAVIGSTCLYAETLACIDDACLRACGVSSNKILALRDLTRREVAGELPS
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCHH
VWQMGSMHHNTIVEKLIPIRGIGRWTVEMMLIFRLGRPDVLPVDDLGVRKGIQRVDSLAF
HHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
VPTPKALCTRGECWAPYRTYAGLYLWRIADFHEGERAVISDRSQDE
CCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCC
>Mature Secondary Structure 
AWYPRGFDVMAAYDYLYHCDPGLSGWMQRLGPLPALRRWRQPFNVVDALARAILFQQLS
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHC
GKAASTIVARIEAVIGSTCLYAETLACIDDACLRACGVSSNKILALRDLTRREVAGELPS
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCHH
VWQMGSMHHNTIVEKLIPIRGIGRWTVEMMLIFRLGRPDVLPVDDLGVRKGIQRVDSLAF
HHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
VPTPKALCTRGECWAPYRTYAGLYLWRIADFHEGERAVISDRSQDE
CCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]