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The map label for this gene is minC

Identifier: 182681156

GI number: 182681156

Start: 707923

End: 708639

Strand: Reverse

Name: minC

Synonym: XfasM23_0598

Alternate gene names: 182681156

Gene position: 708639-707923 (Counterclockwise)

Preceding gene: 182681157

Following gene: 182681155

Centisome position: 27.95

GC content: 53.97

Gene sequence:

>717_bases
ATGTCGAATGTGAACATGGACTTCGAGCAAGCCGGCGAACTGAAAATAGGCCAAGTGGGTATCGCCACTTTGCGCATCCG
TACTCTGAACGTACCACGCCTGATTCAAGAAATGTCTGACCGAGTCACGCGCGCGCCCAAGCTCTTCAGACGCACTGCCG
TGATCCTAGACTTCGGCGAACTCCCGCACCCTCCGGACCTGGCCACTGCAAAAGCACTGGTGGAAGGCTTGCGCGCAGCC
AACGTGCTGCCCGTGGCCATTGCCTATGGGACCAATGAAATTGACCTACTATCGCAACAACTTGGACTACCTCTACTGTC
CAAGTTCCGTGCTCATTACGAACGCCAAGAAGTAGCCGCTCCACCACCCCAATCAACGCCACCTATAAGCACTGGCCGAA
TACAACACACTACCGTGCGGTCCGGTCAACAACTGTATGCAGAGCACTGCGATTTAACCATCCTGAATACAGTCGGCGCA
GGTGCCGAAGTCATCGCCGACGGTAACATCCACATTTATGGGACGCTGCGCGGTCGTGCAATGGCGGGTGCTCGGGGTAA
TGCCGAAATGCGAATATTTTGCCGCGACTTTCAAGCAGAACTGATCGCAATTGCAGGCCGATACAAGGTGCTAGACGACA
TCCCCACTGAACTACGTGGTAAAGCTGTCCAAGTCTGGCTGGAACAAAATCAGATCAAAATTGCTGCGTTGGATTGA

Upstream 100 bases:

>100_bases
CCCCTGGATCCAAGAAACCTACGGTGACAAACTTCCGAACCTCCCCTGGGTAGGCCTGCAACGCCATATCTGCACACCCA
ACTAGGCGGAGAAGCAAATC

Downstream 100 bases:

>100_bases
CGCAGCCTCACCACAGAACGTATCAGGAGAAGTCCTTTGGCTGAAATTATCGTAATCACTTCCGGCAAGGGCGGCGTTGG
CAAAACGACTACCAGCGCAA

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSNVNMDFEQAGELKIGQVGIATLRIRTLNVPRLIQEMSDRVTRAPKLFRRTAVILDFGELPHPPDLATAKALVEGLRAA
NVLPVAIAYGTNEIDLLSQQLGLPLLSKFRAHYERQEVAAPPPQSTPPISTGRIQHTTVRSGQQLYAEHCDLTILNTVGA
GAEVIADGNIHIYGTLRGRAMAGARGNAEMRIFCRDFQAELIAIAGRYKVLDDIPTELRGKAVQVWLEQNQIKIAALD

Sequences:

>Translated_238_residues
MSNVNMDFEQAGELKIGQVGIATLRIRTLNVPRLIQEMSDRVTRAPKLFRRTAVILDFGELPHPPDLATAKALVEGLRAA
NVLPVAIAYGTNEIDLLSQQLGLPLLSKFRAHYERQEVAAPPPQSTPPISTGRIQHTTVRSGQQLYAEHCDLTILNTVGA
GAEVIADGNIHIYGTLRGRAMAGARGNAEMRIFCRDFQAELIAIAGRYKVLDDIPTELRGKAVQVWLEQNQIKIAALD
>Mature_237_residues
SNVNMDFEQAGELKIGQVGIATLRIRTLNVPRLIQEMSDRVTRAPKLFRRTAVILDFGELPHPPDLATAKALVEGLRAAN
VLPVAIAYGTNEIDLLSQQLGLPLLSKFRAHYERQEVAAPPPQSTPPISTGRIQHTTVRSGQQLYAEHCDLTILNTVGAG
AEVIADGNIHIYGTLRGRAMAGARGNAEMRIFCRDFQAELIAIAGRYKVLDDIPTELRGKAVQVWLEQNQIKIAALD

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=214, Percent_Identity=39.2523364485981, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_XYLF2 (B2I967)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829316.1
- ProteinModelPortal:   B2I967
- GeneID:   6202872
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0598
- HOGENOM:   HBG399077
- OMA:   ARIFCRD
- ProtClustDB:   PRK04596
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 26095; Mature: 25963

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVNMDFEQAGELKIGQVGIATLRIRTLNVPRLIQEMSDRVTRAPKLFRRTAVILDFGE
CCCCCCCHHHCCCEEECCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
LPHPPDLATAKALVEGLRAANVLPVAIAYGTNEIDLLSQQLGLPLLSKFRAHYERQEVAA
CCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCCC
PPPQSTPPISTGRIQHTTVRSGQQLYAEHCDLTILNTVGAGAEVIADGNIHIYGTLRGRA
CCCCCCCCCCCCCEEEHHHHCCHHHHHHHCCEEEEECCCCCCEEEECCCEEEEEEECCCE
MAGARGNAEMRIFCRDFQAELIAIAGRYKVLDDIPTELRGKAVQVWLEQNQIKIAALD
EECCCCCCEEEEEEEHHHHHHHHHHCCHHHHHCCCHHHCCCEEEEEEECCEEEEEEEC
>Mature Secondary Structure 
SNVNMDFEQAGELKIGQVGIATLRIRTLNVPRLIQEMSDRVTRAPKLFRRTAVILDFGE
CCCCCCHHHCCCEEECCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
LPHPPDLATAKALVEGLRAANVLPVAIAYGTNEIDLLSQQLGLPLLSKFRAHYERQEVAA
CCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCCC
PPPQSTPPISTGRIQHTTVRSGQQLYAEHCDLTILNTVGAGAEVIADGNIHIYGTLRGRA
CCCCCCCCCCCCCEEEHHHHCCHHHHHHHCCEEEEECCCCCCEEEECCCEEEEEEECCCE
MAGARGNAEMRIFCRDFQAELIAIAGRYKVLDDIPTELRGKAVQVWLEQNQIKIAALD
EECCCCCCEEEEEEEHHHHHHHHHHCCHHHHHCCCHHHCCCEEEEEEECCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA