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The map label for this gene is mreB [H]

Identifier: 182681145

GI number: 182681145

Start: 694221

End: 695264

Strand: Direct

Name: mreB [H]

Synonym: XfasM23_0587

Alternate gene names: 182681145

Gene position: 694221-695264 (Clockwise)

Preceding gene: 182681144

Following gene: 182681146

Centisome position: 27.38

GC content: 54.89

Gene sequence:

>1044_bases
ATGTCCAAGAAGTTGCGCGGTATGTTTTCTAATGATCTGTCCATTGATTTGGGGACAGCAAATACCTTGATTTACGTGCG
GGGGCAAGGGATCGTACTGAACGAGCCATCTGTGGTGGCCGTGCGCCAGGATCGTGCAATTGGCGGTACTCGTTCGGTCG
CTGCGGTGGGTGTCGAAGCCAAGCAGATGTTGGGCCGCACTCCAGGTAATATCACAACGATCCGTCCGATGAAGGATGGC
GTCATCGCCGATTTTACCTACACCGAAGCGATGCTGAAGCACTTCATAAAAAAGGTCCACAAGGCGCGTTTCTTGCGCCC
CAGTCCACGTGTGCTGGTGTGTGTGCCGGCCGGATCCACTCAGGTTGAGCGTCGTGCCATCAAGGAGTCTGCCGAGGAGG
CTGGTGCACGTGATGTTTATTTGATTGAGGAACCGATGGCCGCAGCGATTGGTGCTGGGATGCCGGTCACCGAGGCGCGT
GGTTCGATGGTCATTGACATTGGCGGCGGTACCACTGAGGTTGCGGTGATTTCGTTGAATGGGATTGTGTACTCACAGTC
GGTGCGTATCGGTGGAGATCGCTTCGACGAGTCGATCACTAATTACGTGCGTCGCAACCACGGGATGCTCATTGGTGAGG
CGACTGCTGAGCGGATTAAATTAGAGGTTGGATGCGCCTATCCGCAAGTTGAGGTGCATGAGTTGGAGATTTCTGGACGC
AACCTTGCCGAGGGCGTACCGAAGGTGATCAAGATCAACTCTAATGAGGTGTTGGAGGCGTTGCACGAACCACTCTCTGG
GATTGTTTCGGCAGTGAAATCTGCGTTGGAGCAGACTCCACCGGAGTTGTGCGCCGATGTTGCCGAGCGCGGTATCGTCT
TGACTGGCGGAGGGGCATTGTTACGCGACCTAGATCGGCTGATTTCCGATGAGACTGGCTTATACGTGCAGGTGGCTGAT
GATCCGTTGACGTGCGTGGCTCGTGGTGGTGGCCGTGCGTTAGAGTTGGTTGATATGCATGGCAATGAATTCTTTGCACC
GTAA

Upstream 100 bases:

>100_bases
ATTGTTAATCTAGGCGGCTTTAGAGTTCTTCATTTTGCCTATTTTAAAGCCATCCGGCACATGGGTGTGCATCCTACGTC
TTCCAGGATTGATTTTTCAG

Downstream 100 bases:

>100_bases
TTAGCTGGCATGGTGATTTCGTATGATCCATACATGTTTCGCACAGGATCGGGGAGATATGCTCCAGCTTGGTTTGCGCT
CTCAGGCTAAGATGCAGGCC

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSKKLRGMFSNDLSIDLGTANTLIYVRGQGIVLNEPSVVAVRQDRAIGGTRSVAAVGVEAKQMLGRTPGNITTIRPMKDG
VIADFTYTEAMLKHFIKKVHKARFLRPSPRVLVCVPAGSTQVERRAIKESAEEAGARDVYLIEEPMAAAIGAGMPVTEAR
GSMVIDIGGGTTEVAVISLNGIVYSQSVRIGGDRFDESITNYVRRNHGMLIGEATAERIKLEVGCAYPQVEVHELEISGR
NLAEGVPKVIKINSNEVLEALHEPLSGIVSAVKSALEQTPPELCADVAERGIVLTGGGALLRDLDRLISDETGLYVQVAD
DPLTCVARGGGRALELVDMHGNEFFAP

Sequences:

>Translated_347_residues
MSKKLRGMFSNDLSIDLGTANTLIYVRGQGIVLNEPSVVAVRQDRAIGGTRSVAAVGVEAKQMLGRTPGNITTIRPMKDG
VIADFTYTEAMLKHFIKKVHKARFLRPSPRVLVCVPAGSTQVERRAIKESAEEAGARDVYLIEEPMAAAIGAGMPVTEAR
GSMVIDIGGGTTEVAVISLNGIVYSQSVRIGGDRFDESITNYVRRNHGMLIGEATAERIKLEVGCAYPQVEVHELEISGR
NLAEGVPKVIKINSNEVLEALHEPLSGIVSAVKSALEQTPPELCADVAERGIVLTGGGALLRDLDRLISDETGLYVQVAD
DPLTCVARGGGRALELVDMHGNEFFAP
>Mature_346_residues
SKKLRGMFSNDLSIDLGTANTLIYVRGQGIVLNEPSVVAVRQDRAIGGTRSVAAVGVEAKQMLGRTPGNITTIRPMKDGV
IADFTYTEAMLKHFIKKVHKARFLRPSPRVLVCVPAGSTQVERRAIKESAEEAGARDVYLIEEPMAAAIGAGMPVTEARG
SMVIDIGGGTTEVAVISLNGIVYSQSVRIGGDRFDESITNYVRRNHGMLIGEATAERIKLEVGCAYPQVEVHELEISGRN
LAEGVPKVIKINSNEVLEALHEPLSGIVSAVKSALEQTPPELCADVAERGIVLTGGGALLRDLDRLISDETGLYVQVADD
PLTCVARGGGRALELVDMHGNEFFAP

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Homo sapiens, GI34419635, Length=322, Percent_Identity=27.0186335403727, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87082236, Length=346, Percent_Identity=77.4566473988439, Blast_Score=548, Evalue=1e-157,
Organism=Saccharomyces cerevisiae, GI6324120, Length=385, Percent_Identity=24.4155844155844, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319972, Length=385, Percent_Identity=24.1558441558442, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17647515, Length=256, Percent_Identity=25.78125, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24663992, Length=256, Percent_Identity=25.78125, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24663988, Length=256, Percent_Identity=25.78125, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37127; Mature: 36996

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKLRGMFSNDLSIDLGTANTLIYVRGQGIVLNEPSVVAVRQDRAIGGTRSVAAVGVEA
CCCCCCCCCCCCCEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCCCCCCEEECHHH
KQMLGRTPGNITTIRPMKDGVIADFTYTEAMLKHFIKKVHKARFLRPSPRVLVCVPAGST
HHHHCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCH
QVERRAIKESAEEAGARDVYLIEEPMAAAIGAGMPVTEARGSMVIDIGGGTTEVAVISLN
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEC
GIVYSQSVRIGGDRFDESITNYVRRNHGMLIGEATAERIKLEVGCAYPQVEVHELEISGR
CEEEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEECCCCCEEEEEEEECCC
NLAEGVPKVIKINSNEVLEALHEPLSGIVSAVKSALEQTPPELCADVAERGIVLTGGGAL
CHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCHH
LRDLDRLISDETGLYVQVADDPLTCVARGGGRALELVDMHGNEFFAP
HHHHHHHHCCCCCEEEEECCCCEEEEECCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure 
SKKLRGMFSNDLSIDLGTANTLIYVRGQGIVLNEPSVVAVRQDRAIGGTRSVAAVGVEA
CCCCCCCCCCCCEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCCCCCCEEECHHH
KQMLGRTPGNITTIRPMKDGVIADFTYTEAMLKHFIKKVHKARFLRPSPRVLVCVPAGST
HHHHCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCH
QVERRAIKESAEEAGARDVYLIEEPMAAAIGAGMPVTEARGSMVIDIGGGTTEVAVISLN
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEC
GIVYSQSVRIGGDRFDESITNYVRRNHGMLIGEATAERIKLEVGCAYPQVEVHELEISGR
CEEEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEECCCCCEEEEEEEECCC
NLAEGVPKVIKINSNEVLEALHEPLSGIVSAVKSALEQTPPELCADVAERGIVLTGGGAL
CHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCHH
LRDLDRLISDETGLYVQVADDPLTCVARGGGRALELVDMHGNEFFAP
HHHHHHHHCCCCCEEEEECCCCEEEEECCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]