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The map label for this gene is fadB [H]

Identifier: 182680963

GI number: 182680963

Start: 499171

End: 500043

Strand: Reverse

Name: fadB [H]

Synonym: XfasM23_0401

Alternate gene names: 182680963

Gene position: 500043-499171 (Counterclockwise)

Preceding gene: 182680968

Following gene: 182680951

Centisome position: 19.72

GC content: 48.22

Gene sequence:

>873_bases
ATGTCCGCTGTACATCCCATTCCTCACCCCATATGCGAATCATCCATTCGCATCATCGAAGAAACCCATCGCAATGTGTA
CTGGATCTATATGCATGCTCATCTCGCCAGAACCACGGGAGCCGCCTATTTTTCCTTAAAACTGATTGATGACATCATGA
ATTATCAATCCGTACTTAGACAACGTTTAAAGGAACAAACGGTTCAATTACCATTCGTTGTTCTCGCCTCGGACAGCAAT
GTATTTAATTTAGGCGGGGATCTGCAGCTTTTTTGTGACCTGATACGCCGTAAGGAGCGTGAAGCATTATTGGACTATGC
CTGCCGCTGTGTGCGTGGAGCCTATGCGTTCCATGCTGGGCTCAATGCTAATGTGCATAGCATCGCGCTGCTCCAAGGCA
ATGCGCTTGGAGGAGGCTTCGAAGCTGCGCTCTGTTGCCATACCATCGTAGCTGAAGAAGGTGTGATGATGGGTTTTCCT
GAAGTATTGTTCGATCTTTTCCCAGGCATGGGAGCCTACTCTTTCATGCGTCAACGCATCTCTCCTAAACTGGCCGAACG
CCTCATCCTTGAGGGCAATCTCTACAGTTCCGAAGAATTATTGGCGATTGGGCTGATCGACAAAGTAGTACCGCGCGGCA
AGGGGATAGAAGCAGTCGAGCAAATCATCCGTGACAGCAAACGCCGTCAATATACTTGGGCAGCCATGCAGGAGGTGAAA
AAAATCGCACACGAAGTCTCTTTAGAAGAAATGATACGCATCACCGAACTCTGGGTAGACAGTGCATTGAAACTAAGTAA
CAAATCACTCCGAACTATGGAGCGCCTGATCCGCGCCCAGCAGACTCACAAAAACACAGCACTAAAAAACTGA

Upstream 100 bases:

>100_bases
GTTTTTTGCGCACATAGAATCAAGTGTCGGCCAACACCGTCACTTCCCGCTTCTACGTCCGCAACATGGCCGACCGGACT
ACCATTACGGAGAACAATAA

Downstream 100 bases:

>100_bases
GCACTTAAAGCTGTGCTGATGATCATCGTAAAACCCCACTGCGCCGGCGTTCCTGTCGGCGCGCTTCAAGCGCATCACGA
CCACACAGCAGTGCTTCATC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Enoyl-CoA hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase; 3-hydroxyacyl-CoA dehydrogenase [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSAVHPIPHPICESSIRIIEETHRNVYWIYMHAHLARTTGAAYFSLKLIDDIMNYQSVLRQRLKEQTVQLPFVVLASDSN
VFNLGGDLQLFCDLIRRKEREALLDYACRCVRGAYAFHAGLNANVHSIALLQGNALGGGFEAALCCHTIVAEEGVMMGFP
EVLFDLFPGMGAYSFMRQRISPKLAERLILEGNLYSSEELLAIGLIDKVVPRGKGIEAVEQIIRDSKRRQYTWAAMQEVK
KIAHEVSLEEMIRITELWVDSALKLSNKSLRTMERLIRAQQTHKNTALKN

Sequences:

>Translated_290_residues
MSAVHPIPHPICESSIRIIEETHRNVYWIYMHAHLARTTGAAYFSLKLIDDIMNYQSVLRQRLKEQTVQLPFVVLASDSN
VFNLGGDLQLFCDLIRRKEREALLDYACRCVRGAYAFHAGLNANVHSIALLQGNALGGGFEAALCCHTIVAEEGVMMGFP
EVLFDLFPGMGAYSFMRQRISPKLAERLILEGNLYSSEELLAIGLIDKVVPRGKGIEAVEQIIRDSKRRQYTWAAMQEVK
KIAHEVSLEEMIRITELWVDSALKLSNKSLRTMERLIRAQQTHKNTALKN
>Mature_289_residues
SAVHPIPHPICESSIRIIEETHRNVYWIYMHAHLARTTGAAYFSLKLIDDIMNYQSVLRQRLKEQTVQLPFVVLASDSNV
FNLGGDLQLFCDLIRRKEREALLDYACRCVRGAYAFHAGLNANVHSIALLQGNALGGGFEAALCCHTIVAEEGVMMGFPE
VLFDLFPGMGAYSFMRQRISPKLAERLILEGNLYSSEELLAIGLIDKVVPRGKGIEAVEQIIRDSKRRQYTWAAMQEVKK
IAHEVSLEEMIRITELWVDSALKLSNKSLRTMERLIRAQQTHKNTALKN

Specific function: Catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the 3- hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788682, Length=169, Percent_Identity=27.2189349112426, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787659, Length=125, Percent_Identity=30.4, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790281, Length=178, Percent_Identity=27.5280898876405, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006180
- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR012799
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =4.2.1.17; =5.1.2.3; =5.3.3.8; =1.1.1.35 [H]

Molecular weight: Translated: 32829; Mature: 32697

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVHPIPHPICESSIRIIEETHRNVYWIYMHAHLARTTGAAYFSLKLIDDIMNYQSVLR
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHH
QRLKEQTVQLPFVVLASDSNVFNLGGDLQLFCDLIRRKEREALLDYACRCVRGAYAFHAG
HHHHHHHHCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LNANVHSIALLQGNALGGGFEAALCCHTIVAEEGVMMGFPEVLFDLFPGMGAYSFMRQRI
CCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHH
SPKLAERLILEGNLYSSEELLAIGLIDKVVPRGKGIEAVEQIIRDSKRRQYTWAAMQEVK
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KIAHEVSLEEMIRITELWVDSALKLSNKSLRTMERLIRAQQTHKNTALKN
HHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SAVHPIPHPICESSIRIIEETHRNVYWIYMHAHLARTTGAAYFSLKLIDDIMNYQSVLR
CCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHH
QRLKEQTVQLPFVVLASDSNVFNLGGDLQLFCDLIRRKEREALLDYACRCVRGAYAFHAG
HHHHHHHHCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LNANVHSIALLQGNALGGGFEAALCCHTIVAEEGVMMGFPEVLFDLFPGMGAYSFMRQRI
CCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHH
SPKLAERLILEGNLYSSEELLAIGLIDKVVPRGKGIEAVEQIIRDSKRRQYTWAAMQEVK
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KIAHEVSLEEMIRITELWVDSALKLSNKSLRTMERLIRAQQTHKNTALKN
HHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA