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The map label for this gene is exbB [H]

Identifier: 182680913

GI number: 182680913

Start: 449577

End: 450239

Strand: Direct

Name: exbB [H]

Synonym: XfasM23_0351

Alternate gene names: 182680913

Gene position: 449577-450239 (Clockwise)

Preceding gene: 182680912

Following gene: 182680914

Centisome position: 17.73

GC content: 50.83

Gene sequence:

>663_bases
ATGCTGGAACTGGTAAAGGCTGGCGGCTGGCCGATGTTGCCGCTGTTGATGTTAGGTGTTGTTGCATTGGCGATTGTGCT
TGAAAGGCTGTGGACTCTGCGTCGTAATGAGGTATTGCCGTCGGGGCTGGGTCGGGAGGTTCGTGAGTGGGTGAGGCGTG
GCAAATTGGACCAAAATCATCTTGAGTCTCTGCGCCGTAATTCTCCGCTTGGTGCGCTATTGGCCGCCGCTTTGGATGTA
AAAGGTGGCGTACGTGAAATGATTCGTGAACGTATTGAGGATACAGGGCGCCATCTGGTGCATCGCATGGAGCGTTTTCT
GAATGCACTCGGTACGATTGCTTCTGCAGGTCCTTTACTTGGTTTGCTAGGTACTGTGGTCGGTATGATTCAAATGTTCC
TGGGGATTCTCGATTATGGCGTGGGCGATGTGAATCAGCTTGCTGGAGGGATTGGCAAGGCATTGGTTTGCACTGCTACA
GGTATGATTATTGCGATTCCCGCTCTGATTTTTCATCGTTATTTCAAGGGGCGAATTACTGGGTACGTGATTGAGATGGA
GCAAGAGGCAATGCTCTTGCTGGATGCGATTGATGGTCTTCAGATTGCTATTCAAGGAAGAAATGCCGAAGTGGCGCACC
CCAATGCTGTCACCAAGGATTGA

Upstream 100 bases:

>100_bases
TTTGGCGTCGTCGATTCTGGGATGCGGTCGAACGTCGCCGATCCGCTGCTATCCTATCCGCCACTGAAGATGTATCCAAA
GAGCGTCGGAGAAACGAGAC

Downstream 100 bases:

>100_bases
TGAGATGCGTATAGGGAATCAGCGTCTCGAAGACGAGCCACACATCGATTTGGTCCCGCTGATTGATGTGATTTTGGTTT
TGATCATTTTTTTCGTAGTA

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MLELVKAGGWPMLPLLMLGVVALAIVLERLWTLRRNEVLPSGLGREVREWVRRGKLDQNHLESLRRNSPLGALLAAALDV
KGGVREMIRERIEDTGRHLVHRMERFLNALGTIASAGPLLGLLGTVVGMIQMFLGILDYGVGDVNQLAGGIGKALVCTAT
GMIIAIPALIFHRYFKGRITGYVIEMEQEAMLLLDAIDGLQIAIQGRNAEVAHPNAVTKD

Sequences:

>Translated_220_residues
MLELVKAGGWPMLPLLMLGVVALAIVLERLWTLRRNEVLPSGLGREVREWVRRGKLDQNHLESLRRNSPLGALLAAALDV
KGGVREMIRERIEDTGRHLVHRMERFLNALGTIASAGPLLGLLGTVVGMIQMFLGILDYGVGDVNQLAGGIGKALVCTAT
GMIIAIPALIFHRYFKGRITGYVIEMEQEAMLLLDAIDGLQIAIQGRNAEVAHPNAVTKD
>Mature_220_residues
MLELVKAGGWPMLPLLMLGVVALAIVLERLWTLRRNEVLPSGLGREVREWVRRGKLDQNHLESLRRNSPLGALLAAALDV
KGGVREMIRERIEDTGRHLVHRMERFLNALGTIASAGPLLGLLGTVVGMIQMFLGILDYGVGDVNQLAGGIGKALVCTAT
GMIIAIPALIFHRYFKGRITGYVIEMEQEAMLLLDAIDGLQIAIQGRNAEVAHPNAVTKD

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=109, Percent_Identity=33.0275229357798, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 24001; Mature: 24001

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELVKAGGWPMLPLLMLGVVALAIVLERLWTLRRNEVLPSGLGREVREWVRRGKLDQNH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHH
LESLRRNSPLGALLAAALDVKGGVREMIRERIEDTGRHLVHRMERFLNALGTIASAGPLL
HHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLGTVVGMIQMFLGILDYGVGDVNQLAGGIGKALVCTATGMIIAIPALIFHRYFKGRIT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYVIEMEQEAMLLLDAIDGLQIAIQGRNAEVAHPNAVTKD
HEEEEEHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MLELVKAGGWPMLPLLMLGVVALAIVLERLWTLRRNEVLPSGLGREVREWVRRGKLDQNH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHH
LESLRRNSPLGALLAAALDVKGGVREMIRERIEDTGRHLVHRMERFLNALGTIASAGPLL
HHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLGTVVGMIQMFLGILDYGVGDVNQLAGGIGKALVCTATGMIIAIPALIFHRYFKGRIT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYVIEMEQEAMLLLDAIDGLQIAIQGRNAEVAHPNAVTKD
HEEEEEHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8437515 [H]