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The map label for this gene is sdhB

Identifier: 182680907

GI number: 182680907

Start: 443237

End: 444022

Strand: Direct

Name: sdhB

Synonym: XfasM23_0345

Alternate gene names: 182680907

Gene position: 443237-444022 (Clockwise)

Preceding gene: 182680906

Following gene: 182680908

Centisome position: 17.48

GC content: 50.25

Gene sequence:

>786_bases
ATGGCAGAGTTCACTCTCCCTAAGAATTCGAAGATCGGTAAGGGGACGCATTTCCCCGCCAAAAGCGGTACTAAAAATGC
TCGCACCTTTAAGGTCTACCGTTGGAATCCGGATGATGATGCCAATCCGCGTACCGATACCTACGAAATTGATCTAGATA
CATGCGGCCCGATGGTTTTGGATGCGTTGATCAAGATTAAGAATGAGATCGACCCGACTCTGACGTTCCGTCGTTCTTGC
CGCGAGGGTATTTGTGGCTCATGTGCGATGAACATTGATGGGACCAACACGTTAGCTTGTACCAAGGCGATTAGTGCATG
CACCATATCTGAGATCCCGATCTATCCACTGCCTCACATGAACGTGATCAAGGATTTGATCCCCGACTTGACTCACTTTT
ATGCGCAGTACGCTTCTATTAAGCCCTGGATACGTACTCAGACCCCGCCGCCGCCTGATCGTGAGCGATTGCAGTCTCCT
GTGGACCGCAAGAAGCTTGATGGTTTGTATGAGTGCATTCTATGTGCCTGTTGCTCGACGAGTTGTCCGAGTTACTGGTG
GAATGGTGATCGCTATTTGGGTCCGGCGATCTTGCTGCAGGCTTACCGCTGGATTATCGATTCACGTGATGAAGATACTG
GCGCGCGCTTGGATGATCTCGAGGATCCATTCAAGTTATATCGTTGTCATACCATCATGAATTGCACGCGAACCTGTCCG
AAGGGATTGAATCCCGCTCAGGCCATTGCCGAGATCAAAAAACTGATGATGCTGCGTCGCGCCTGA

Upstream 100 bases:

>100_bases
GTTTTGACTACCGCCCTGTGCACATGTACACGCTCAGCAAAGACGTGGATGTGATACCTCCTAAGCCGCGCGTCTATTGA
CCTAGCTGGATATAAATGTC

Downstream 100 bases:

>100_bases
GACTAAAGAATGCGAATAGGATGCATTAGTCACCAAACGAAGGTAGTGCTGGTATTAAATTGACGCCTCTGCTGCTTGCG
CTATTGCCGATGCCAGCGTG

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MAEFTLPKNSKIGKGTHFPAKSGTKNARTFKVYRWNPDDDANPRTDTYEIDLDTCGPMVLDALIKIKNEIDPTLTFRRSC
REGICGSCAMNIDGTNTLACTKAISACTISEIPIYPLPHMNVIKDLIPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSP
VDRKKLDGLYECILCACCSTSCPSYWWNGDRYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCTRTCP
KGLNPAQAIAEIKKLMMLRRA

Sequences:

>Translated_261_residues
MAEFTLPKNSKIGKGTHFPAKSGTKNARTFKVYRWNPDDDANPRTDTYEIDLDTCGPMVLDALIKIKNEIDPTLTFRRSC
REGICGSCAMNIDGTNTLACTKAISACTISEIPIYPLPHMNVIKDLIPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSP
VDRKKLDGLYECILCACCSTSCPSYWWNGDRYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCTRTCP
KGLNPAQAIAEIKKLMMLRRA
>Mature_260_residues
AEFTLPKNSKIGKGTHFPAKSGTKNARTFKVYRWNPDDDANPRTDTYEIDLDTCGPMVLDALIKIKNEIDPTLTFRRSCR
EGICGSCAMNIDGTNTLACTKAISACTISEIPIYPLPHMNVIKDLIPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSPV
DRKKLDGLYECILCACCSTSCPSYWWNGDRYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCTRTCPK
GLNPAQAIAEIKKLMMLRRA

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=231, Percent_Identity=69.2640692640693, Blast_Score=346, Evalue=1e-95,
Organism=Escherichia coli, GI1786943, Length=235, Percent_Identity=56.1702127659575, Blast_Score=274, Evalue=4e-75,
Organism=Escherichia coli, GI1790596, Length=224, Percent_Identity=32.5892857142857, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17533915, Length=238, Percent_Identity=63.4453781512605, Blast_Score=326, Evalue=7e-90,
Organism=Saccharomyces cerevisiae, GI6322987, Length=228, Percent_Identity=67.9824561403509, Blast_Score=331, Evalue=6e-92,
Organism=Drosophila melanogaster, GI17137106, Length=242, Percent_Identity=65.2892561983471, Blast_Score=350, Evalue=8e-97,
Organism=Drosophila melanogaster, GI24643156, Length=232, Percent_Identity=65.0862068965517, Blast_Score=326, Evalue=8e-90,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29587; Mature: 29456

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
5.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEFTLPKNSKIGKGTHFPAKSGTKNARTFKVYRWNPDDDANPRTDTYEIDLDTCGPMVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEECCCCCHHHH
DALIKIKNEIDPTLTFRRSCREGICGSCAMNIDGTNTLACTKAISACTISEIPIYPLPHM
HHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCH
NVIKDLIPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSPVDRKKLDGLYECILCACCST
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCC
SCPSYWWNGDRYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCTRTCP
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
KGLNPAQAIAEIKKLMMLRRA
CCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEFTLPKNSKIGKGTHFPAKSGTKNARTFKVYRWNPDDDANPRTDTYEIDLDTCGPMVL
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEECCCCCHHHH
DALIKIKNEIDPTLTFRRSCREGICGSCAMNIDGTNTLACTKAISACTISEIPIYPLPHM
HHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCH
NVIKDLIPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSPVDRKKLDGLYECILCACCST
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCC
SCPSYWWNGDRYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCTRTCP
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
KGLNPAQAIAEIKKLMMLRRA
CCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA