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The map label for this gene is glk

Identifier: 182680899

GI number: 182680899

Start: 435238

End: 436251

Strand: Reverse

Name: glk

Synonym: XfasM23_0337

Alternate gene names: 182680899

Gene position: 436251-435238 (Counterclockwise)

Preceding gene: 182680900

Following gene: 182680898

Centisome position: 17.2

GC content: 57.59

Gene sequence:

>1014_bases
ATGAACGCACCACAGGCTCCCGTACTGGTCGCAGACATTGGAGGGACTAACGCCCGCTTTGCGCTCGCCAACCCCACCCT
AACCTCAGCACCACTGCTGAACGACAGCATGCGCGAATTCGCCGTCATCGAATTCCCCTCACTGGGCGAAGCTGCACAGC
ACTACCTGCATCACATCGGCATACATACCACCAAAGGCGTCTTTGCGATCGCCGGACACGTAGACGGCGATGAAGCACGT
ATTACCAATCATCCCTGGGTCATCACACGCACGCGCACTGCAACAATGCTCGGCTTCGACACCCTGCACCTCATCAACGA
TTTTGTTGCCCAAGCGATGGCCATCAGCGTGTTAGGCCCTCAAGATGTCATCCAAATCGGCAGTGCCAAATGGGAGCAAT
TCCCGCTATCAGCAGCCACTCGCAACTACGGCATCATTGGCCCCGGCACCGGCCTAGGCGTCGGCGGCCTGATGATTCGC
AACGGCCGCTGCTATCCGCTAGAAACCGAGGGCGGCCATGTCAGCTTCCCGCCAAGCACCCCAGAAGAAATCCGGATCCT
GGAAATCCTGTCACAACAATTCGGACGTGTCTCCAACGAACGGCTGATCTCCGGTCCAGGGATAGTCAACATTCACCGCG
CACTGAGCGAAATCGACGGAATCGACCCAGGTCCACTGCGCCCTCAAGACATCACCATGCGCGCCGCTGACGGCGACATA
CGCGCCACACGCACCATCAATCTGTTCTGCAACATCTTCGGCACCATCACCGGCGACCTGGTACTCATCCAAGGGGCTTG
GGATGGCGTCTTTCTGACAGGCGGCCTCGTTCCCAAACTATTGAACTCAATACAGCATTCCGGTTTCCGCCAAAGATTTG
AACATAAGGGTCGATTTTCGGCCATCATGGCCCGTATCCCCTCTTTGGCAGTGATCCATCCACACCCTGGCCTACTCGGC
GCAGCCGCATACGCACGAGACACCGAGCAAGTCCCGCAGGAAATCAAGGCATGA

Upstream 100 bases:

>100_bases
CCGACTTACCACTGCAACCCTACCCCGCCGGCGGCTGGGGCCCACCTCAAGCCCACCAATTTCTGCCGCCATTGGGGATT
GATGGCCATGGAAACAACGC

Downstream 100 bases:

>100_bases
TCCCTACAAACGACGCACACATCACCTTGATGAACTACGACGACCCGCTGGAGTGGGCACAGAGTGTCACCAGAGAATTG
GAGAACATCCTCCTCCAAGA

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MNAPQAPVLVADIGGTNARFALANPTLTSAPLLNDSMREFAVIEFPSLGEAAQHYLHHIGIHTTKGVFAIAGHVDGDEAR
ITNHPWVITRTRTATMLGFDTLHLINDFVAQAMAISVLGPQDVIQIGSAKWEQFPLSAATRNYGIIGPGTGLGVGGLMIR
NGRCYPLETEGGHVSFPPSTPEEIRILEILSQQFGRVSNERLISGPGIVNIHRALSEIDGIDPGPLRPQDITMRAADGDI
RATRTINLFCNIFGTITGDLVLIQGAWDGVFLTGGLVPKLLNSIQHSGFRQRFEHKGRFSAIMARIPSLAVIHPHPGLLG
AAAYARDTEQVPQEIKA

Sequences:

>Translated_337_residues
MNAPQAPVLVADIGGTNARFALANPTLTSAPLLNDSMREFAVIEFPSLGEAAQHYLHHIGIHTTKGVFAIAGHVDGDEAR
ITNHPWVITRTRTATMLGFDTLHLINDFVAQAMAISVLGPQDVIQIGSAKWEQFPLSAATRNYGIIGPGTGLGVGGLMIR
NGRCYPLETEGGHVSFPPSTPEEIRILEILSQQFGRVSNERLISGPGIVNIHRALSEIDGIDPGPLRPQDITMRAADGDI
RATRTINLFCNIFGTITGDLVLIQGAWDGVFLTGGLVPKLLNSIQHSGFRQRFEHKGRFSAIMARIPSLAVIHPHPGLLG
AAAYARDTEQVPQEIKA
>Mature_337_residues
MNAPQAPVLVADIGGTNARFALANPTLTSAPLLNDSMREFAVIEFPSLGEAAQHYLHHIGIHTTKGVFAIAGHVDGDEAR
ITNHPWVITRTRTATMLGFDTLHLINDFVAQAMAISVLGPQDVIQIGSAKWEQFPLSAATRNYGIIGPGTGLGVGGLMIR
NGRCYPLETEGGHVSFPPSTPEEIRILEILSQQFGRVSNERLISGPGIVNIHRALSEIDGIDPGPLRPQDITMRAADGDI
RATRTINLFCNIFGTITGDLVLIQGAWDGVFLTGGLVPKLLNSIQHSGFRQRFEHKGRFSAIMARIPSLAVIHPHPGLLG
AAAYARDTEQVPQEIKA

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family

Homologues:

Organism=Escherichia coli, GI1788732, Length=321, Percent_Identity=41.1214953271028, Blast_Score=230, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLK_XYLF2 (B2I7Q9)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829059.1
- ProteinModelPortal:   B2I7Q9
- GeneID:   6201921
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0337
- HOGENOM:   HBG644410
- OMA:   LGMTRLK
- ProtClustDB:   PRK00292
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00524
- InterPro:   IPR003836
- TIGRFAMs:   TIGR00749

Pfam domain/function: PF02685 Glucokinase

EC number: =2.7.1.2

Molecular weight: Translated: 36273; Mature: 36273

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPQAPVLVADIGGTNARFALANPTLTSAPLLNDSMREFAVIEFPSLGEAAQHYLHHIG
CCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCHHHEEEEECCCCCHHHHHHHHHHC
IHTTKGVFAIAGHVDGDEARITNHPWVITRTRTATMLGFDTLHLINDFVAQAMAISVLGP
CCCCCCEEEEEECCCCCCCEECCCCEEEEECCEEEEECHHHHHHHHHHHHHHHHEEECCC
QDVIQIGSAKWEQFPLSAATRNYGIIGPGTGLGVGGLMIRNGRCYPLETEGGHVSFPPST
HHHHHHCCCCHHHCCCHHHCCCCCEECCCCCCCCCEEEEECCEEEEEECCCCEEECCCCC
PEEIRILEILSQQFGRVSNERLISGPGIVNIHRALSEIDGIDPGPLRPQDITMRAADGDI
HHHHHHHHHHHHHHCCCCCCEEECCCCEEHHHHHHHHHCCCCCCCCCCCCEEEEECCCCE
RATRTINLFCNIFGTITGDLVLIQGAWDGVFLTGGLVPKLLNSIQHSGFRQRFEHKGRFS
EEEEEEEEEEEEHHCCCCCEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCHHH
AIMARIPSLAVIHPHPGLLGAAAYARDTEQVPQEIKA
HHHHHCCCEEEECCCCCHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MNAPQAPVLVADIGGTNARFALANPTLTSAPLLNDSMREFAVIEFPSLGEAAQHYLHHIG
CCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCHHHEEEEECCCCCHHHHHHHHHHC
IHTTKGVFAIAGHVDGDEARITNHPWVITRTRTATMLGFDTLHLINDFVAQAMAISVLGP
CCCCCCEEEEEECCCCCCCEECCCCEEEEECCEEEEECHHHHHHHHHHHHHHHHEEECCC
QDVIQIGSAKWEQFPLSAATRNYGIIGPGTGLGVGGLMIRNGRCYPLETEGGHVSFPPST
HHHHHHCCCCHHHCCCHHHCCCCCEECCCCCCCCCEEEEECCEEEEEECCCCEEECCCCC
PEEIRILEILSQQFGRVSNERLISGPGIVNIHRALSEIDGIDPGPLRPQDITMRAADGDI
HHHHHHHHHHHHHHCCCCCCEEECCCCEEHHHHHHHHHCCCCCCCCCCCCEEEEECCCCE
RATRTINLFCNIFGTITGDLVLIQGAWDGVFLTGGLVPKLLNSIQHSGFRQRFEHKGRFS
EEEEEEEEEEEEHHCCCCCEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCHHH
AIMARIPSLAVIHPHPGLLGAAAYARDTEQVPQEIKA
HHHHHCCCEEEECCCCCHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA