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The map label for this gene is mntH [H]

Identifier: 182680865

GI number: 182680865

Start: 387032

End: 388390

Strand: Direct

Name: mntH [H]

Synonym: XfasM23_0302

Alternate gene names: 182680865

Gene position: 387032-388390 (Clockwise)

Preceding gene: 182680862

Following gene: 182680871

Centisome position: 15.26

GC content: 54.89

Gene sequence:

>1359_bases
ATGTCTTCTTCTATGTCTTCGGTTCAGCCTACGTCTCCAGTGTCGGATTCTCCCAGTCTTGGGGAGATGCATGCCAGTGT
CGCGGTGTCGCGCAGGGGGCATTGGGGGTTCCGTTTGTTGGCCTTTTTGGGGCCGGGCTATATGGTGTCGGTCGGTTATA
TGGATCCGGGCAATTGGGCGACGGGGTTGGCGGGTGGTTCGCGTTTTGGCTATATGTTGTTGTCGGTGATTTTGCTCTCC
AATGTGATGGCGATTGTGTTGCAGGCGTTGGCGGCGCGTTTAGGGATTGCCAGTGATATGGATTTGGCGCAGGCGTGCCG
TGCGCGTTATTCACGTGGGACGAATCTGGCGTTGTGGGCGGTCTGTGAGTTGGCGATTATTGCGTGTGATTTGGCGGAGG
TGATCGGTACGGCGATTGCGCTCAATTTGTTGTTAGGGGTTCCAATCATTTTGGGGGCCGTGATCACGGCGGTTGATGTG
GTCTTGGTGTTGTTGTTGATGCATCGTGGTTTCCGTGCGCTTGAGGCGTTTGTGATCGCGTTGTTGTTGGTGATTTTTGG
GTGTTTCGTGGTTCAAATTGTGTTGGCTGCGCCTCCGTTGCAGGAGGTGTTGGGTGGTTTTGTGCCGCGTTGGCAGGTGG
TTGCTGATCCTCAAGCGCTGTATTTGGCGATCGGTATTGTCGGTGCGACGGTGATGCCGCATAACTTGTATTTGCATTCT
TCGATTGTGCAGACGCGTGCTTATCCGCGTACGCCGGTGGGGCGACGTTCGGCGTTGCGTTGGGCTGTGGCCGACAGTAC
TTTGGCGTTGATGTTGGCGTTGTTTATCAATGCGTCGATTCTGATTCTTGCTGCGGCGGTGTTTCATGCGCAGCATCATT
TTGATGTGGAGGAAATCGAGCAGGCGTATCAGTTGCTCGCGCCGGTCCTTGGGGTTGGGGTGGCTGCGACGTTGTTTGCA
ACGGCATTGTTGGCGTCAGGGATCAATTCAACGGTCACGGCGACGTTGGCAGGGCAGATCGTGATGGAGGGGTTTTTGCG
GTTGCGGTTGCGGCCGTGGTTGCGGCGTGTGTTGACCCGCGGTTTGGCGATTGTGCCGGTGATTGTTGTGGTAGCGCTGT
ATGGGGAGCAAGGGACCGGGCGCTTGCTGCTGTTGAGTCAAGTGATTTTGTCGATGCAGTTGCCGTTTGCGGTGATTCCG
TTATTGCGTTGTGTTGCGGATCGTAAGGTGATGGGTGCGTTGGTGGCGCCACGTTGGTTAATGGTGGTTGCGTGGTTGAT
TGCTGGGGTGATTGTCGTACTCAATGTTAAGTTGTTGGGCGATTATGCTGTTCATTTGATGGTTGGTGTCAGTGATTGA

Upstream 100 bases:

>100_bases
TGTTTAGTTGTGTTTGGTATGGGCAGCGATTTTTTGTAGGGTGAGTTGCTGTATAGCCAATGCTATAAGATGGGATGTGT
CGTTGCTTATTCATCGTTCT

Downstream 100 bases:

>100_bases
ACAGTGGTTAGGTGATTGATCCGGCGAGGGCGTTGCAGTCAATGGTCATGGTGTTTTGTGTTTATGCATCGGTTTGCTGT
GTTTCAAGGGGCTTTTTATG

Product: manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSSSMSSVQPTSPVSDSPSLGEMHASVAVSRRGHWGFRLLAFLGPGYMVSVGYMDPGNWATGLAGGSRFGYMLLSVILLS
NVMAIVLQALAARLGIASDMDLAQACRARYSRGTNLALWAVCELAIIACDLAEVIGTAIALNLLLGVPIILGAVITAVDV
VLVLLLMHRGFRALEAFVIALLLVIFGCFVVQIVLAAPPLQEVLGGFVPRWQVVADPQALYLAIGIVGATVMPHNLYLHS
SIVQTRAYPRTPVGRRSALRWAVADSTLALMLALFINASILILAAAVFHAQHHFDVEEIEQAYQLLAPVLGVGVAATLFA
TALLASGINSTVTATLAGQIVMEGFLRLRLRPWLRRVLTRGLAIVPVIVVVALYGEQGTGRLLLLSQVILSMQLPFAVIP
LLRCVADRKVMGALVAPRWLMVVAWLIAGVIVVLNVKLLGDYAVHLMVGVSD

Sequences:

>Translated_452_residues
MSSSMSSVQPTSPVSDSPSLGEMHASVAVSRRGHWGFRLLAFLGPGYMVSVGYMDPGNWATGLAGGSRFGYMLLSVILLS
NVMAIVLQALAARLGIASDMDLAQACRARYSRGTNLALWAVCELAIIACDLAEVIGTAIALNLLLGVPIILGAVITAVDV
VLVLLLMHRGFRALEAFVIALLLVIFGCFVVQIVLAAPPLQEVLGGFVPRWQVVADPQALYLAIGIVGATVMPHNLYLHS
SIVQTRAYPRTPVGRRSALRWAVADSTLALMLALFINASILILAAAVFHAQHHFDVEEIEQAYQLLAPVLGVGVAATLFA
TALLASGINSTVTATLAGQIVMEGFLRLRLRPWLRRVLTRGLAIVPVIVVVALYGEQGTGRLLLLSQVILSMQLPFAVIP
LLRCVADRKVMGALVAPRWLMVVAWLIAGVIVVLNVKLLGDYAVHLMVGVSD
>Mature_451_residues
SSSMSSVQPTSPVSDSPSLGEMHASVAVSRRGHWGFRLLAFLGPGYMVSVGYMDPGNWATGLAGGSRFGYMLLSVILLSN
VMAIVLQALAARLGIASDMDLAQACRARYSRGTNLALWAVCELAIIACDLAEVIGTAIALNLLLGVPIILGAVITAVDVV
LVLLLMHRGFRALEAFVIALLLVIFGCFVVQIVLAAPPLQEVLGGFVPRWQVVADPQALYLAIGIVGATVMPHNLYLHSS
IVQTRAYPRTPVGRRSALRWAVADSTLALMLALFINASILILAAAVFHAQHHFDVEEIEQAYQLLAPVLGVGVAATLFAT
ALLASGINSTVTATLAGQIVMEGFLRLRLRPWLRRVLTRGLAIVPVIVVVALYGEQGTGRLLLLSQVILSMQLPFAVIPL
LRCVADRKVMGALVAPRWLMVVAWLIAGVIVVLNVKLLGDYAVHLMVGVSD

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI295293167, Length=472, Percent_Identity=35.3813559322034, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI295293175, Length=472, Percent_Identity=35.3813559322034, Blast_Score=210, Evalue=3e-54,
Organism=Homo sapiens, GI295293173, Length=472, Percent_Identity=35.3813559322034, Blast_Score=210, Evalue=3e-54,
Organism=Homo sapiens, GI10835169, Length=472, Percent_Identity=35.3813559322034, Blast_Score=210, Evalue=3e-54,
Organism=Homo sapiens, GI295293178, Length=472, Percent_Identity=35.3813559322034, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI295293171, Length=472, Percent_Identity=35.3813559322034, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI295293169, Length=472, Percent_Identity=35.3813559322034, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI109255241, Length=395, Percent_Identity=36.7088607594937, Blast_Score=208, Evalue=8e-54,
Organism=Escherichia coli, GI1788736, Length=401, Percent_Identity=39.9002493765586, Blast_Score=268, Evalue=5e-73,
Organism=Caenorhabditis elegans, GI193210616, Length=434, Percent_Identity=33.1797235023041, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17569473, Length=401, Percent_Identity=31.9201995012469, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71999499, Length=436, Percent_Identity=31.651376146789, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71993856, Length=209, Percent_Identity=39.7129186602871, Blast_Score=150, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6321841, Length=402, Percent_Identity=40.547263681592, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6323062, Length=394, Percent_Identity=39.5939086294416, Blast_Score=259, Evalue=6e-70,
Organism=Saccharomyces cerevisiae, GI6324450, Length=418, Percent_Identity=36.1244019138756, Blast_Score=248, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24648607, Length=456, Percent_Identity=32.6754385964912, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI281362176, Length=456, Percent_Identity=32.6754385964912, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24648609, Length=456, Percent_Identity=32.6754385964912, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI45553443, Length=410, Percent_Identity=33.9024390243902, Blast_Score=214, Evalue=9e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 48185; Mature: 48054

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSMSSVQPTSPVSDSPSLGEMHASVAVSRRGHWGFRLLAFLGPGYMVSVGYMDPGNWA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCC
TGLAGGSRFGYMLLSVILLSNVMAIVLQALAARLGIASDMDLAQACRARYSRGTNLALWA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHH
VCELAIIACDLAEVIGTAIALNLLLGVPIILGAVITAVDVVLVLLLMHRGFRALEAFVIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LLLVIFGCFVVQIVLAAPPLQEVLGGFVPRWQVVADPQALYLAIGIVGATVMPHNLYLHS
HHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHHH
SIVQTRAYPRTPVGRRSALRWAVADSTLALMLALFINASILILAAAVFHAQHHFDVEEIE
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
QAYQLLAPVLGVGVAATLFATALLASGINSTVTATLAGQIVMEGFLRLRLRPWLRRVLTR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLAIVPVIVVVALYGEQGTGRLLLLSQVILSMQLPFAVIPLLRCVADRKVMGALVAPRWL
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MVVAWLIAGVIVVLNVKLLGDYAVHLMVGVSD
HHHHHHHHHHHHHHHHHHHHHEEEEEEEECCC
>Mature Secondary Structure 
SSSMSSVQPTSPVSDSPSLGEMHASVAVSRRGHWGFRLLAFLGPGYMVSVGYMDPGNWA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCC
TGLAGGSRFGYMLLSVILLSNVMAIVLQALAARLGIASDMDLAQACRARYSRGTNLALWA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHH
VCELAIIACDLAEVIGTAIALNLLLGVPIILGAVITAVDVVLVLLLMHRGFRALEAFVIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LLLVIFGCFVVQIVLAAPPLQEVLGGFVPRWQVVADPQALYLAIGIVGATVMPHNLYLHS
HHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHHH
SIVQTRAYPRTPVGRRSALRWAVADSTLALMLALFINASILILAAAVFHAQHHFDVEEIE
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
QAYQLLAPVLGVGVAATLFATALLASGINSTVTATLAGQIVMEGFLRLRLRPWLRRVLTR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLAIVPVIVVVALYGEQGTGRLLLLSQVILSMQLPFAVIPLLRCVADRKVMGALVAPRWL
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MVVAWLIAGVIVVLNVKLLGDYAVHLMVGVSD
HHHHHHHHHHHHHHHHHHHHHEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]