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The map label for this gene is argB [H]

Identifier: 182680850

GI number: 182680850

Start: 370277

End: 371593

Strand: Direct

Name: argB [H]

Synonym: XfasM23_0287

Alternate gene names: 182680850

Gene position: 370277-371593 (Clockwise)

Preceding gene: 182680849

Following gene: 182680851

Centisome position: 14.6

GC content: 55.2

Gene sequence:

>1317_bases
ATGCACGCCAACCTACAGACTCGACAGATCATCATCCGCCTGCTGTCAAGCATGGCGAGCGCCAAGGAAATTAGCCAATA
CCTCAAGCGATTCTCCCAATTGGATGCAAAACGCTTTGCTGTCGTCAAAGTTGGCGGCGCCGTACTGCGCGATGATGTGG
ACGCACTGACCTCCTCCCTCTCATTCCTCCAAGAGGTGGGACTCACCCCGATTGTCCTGCACGGCGCCGGTCCCCAATTG
GATGAAGAACTCACTGCTGTCGGCATTCAAAAAAAGACCGTCAACGGCTTCCGTGTCACCTTGCCAGAGACAATGGCCAT
CGTCCGCAAAGTGTTTCATGCCACCAACCTCCAACTCATCGAAGCATTACAGCGCAACGGCGCCCGCGCCACCTCCATCA
CCGGCGGAGTATTTGAAGCACACTACCTTGACCAAGAAACCTACGGCCTTGTGGGCGGAATCTCCGCCGTCAACATCGCA
CCGATTGAGGCCAGCTTGCGTGCCGCCTCTATTCCCGTCATTGCCAGCCTCGGCGAAACTCCCAGCGGCCAAATTCTCAA
CATCAATGCCGATGTTGCCGCCAATGAACTCGTACACGTCCTCCAGCCCTACAAAATCATCTTTCTCACCGGCACGGGCG
GCTTACTTGATGCCGATGGAAAAATCATTAACTCAATCAACCTATCCACCGAATACGAACAACTCATCCAGCAGCCCTGG
GTCTATGGCGGCATGAAACTCAAGATCGAACAGATCAAACACCTCCTGGACCGACTGCCCCTAGAATCCTCAGTCTCCAT
CACCCGCCCCGCCGACCTTGCCAAAGAACTGTTTACCCACAAAGGCTCCGGCACCCTGATACGCCGTGGCGAACGAGTCA
TCCGCGCCACCACATGGAAAGACCTAGACCTCCCGCGCCTCCAACACCTCATCCAATCCAGCTTCAGGCGTACCCTGATC
CCCCATTACTTCGAAACCACCCCCTTACTGCGCGCCTATGTCAGCGAAAACTACCGCGCTGCCGTGATCCTGACCAAGCT
GGGTAACGTCCCATACCTAGATAAATTCGCCGTATTGGACGACGCACAGGGAGAAGGCCTCGGCCGTGCCGTCTGGAGCA
TCATGCGCGAAGAAACACCCCAACTCTTCTGGCGTTCCCGCCACAACAACCAAGCCAATGCTTTTTACTACGCCGAATCC
GATGGCTACTACAAACAAGACCACTGGAAAATCTTTTGGAATGGCCTACATCACTTCCAACAGATCCAACAATGCGTCGC
CCACTGCACCCAACATCCCCCAACCCTGATCGATTGA

Upstream 100 bases:

>100_bases
GCCGAATCCGTTTACCGCATCATCAATGCCACCTAACCTCCGGCATCGCTAATTATTTGGTCCTCCCGGGCGCGTCCGTC
CCCCAACCACCGCCAATCCA

Downstream 100 bases:

>100_bases
AGATGAGCACTGCCACCTTCACCCTTGGCATTGTTGGTGCCCGCGGCTACACCGGCGCCGCATTGATCACCCTCCTGACT
GCCCACCCCGCGATTGAACT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MHANLQTRQIIIRLLSSMASAKEISQYLKRFSQLDAKRFAVVKVGGAVLRDDVDALTSSLSFLQEVGLTPIVLHGAGPQL
DEELTAVGIQKKTVNGFRVTLPETMAIVRKVFHATNLQLIEALQRNGARATSITGGVFEAHYLDQETYGLVGGISAVNIA
PIEASLRAASIPVIASLGETPSGQILNINADVAANELVHVLQPYKIIFLTGTGGLLDADGKIINSINLSTEYEQLIQQPW
VYGGMKLKIEQIKHLLDRLPLESSVSITRPADLAKELFTHKGSGTLIRRGERVIRATTWKDLDLPRLQHLIQSSFRRTLI
PHYFETTPLLRAYVSENYRAAVILTKLGNVPYLDKFAVLDDAQGEGLGRAVWSIMREETPQLFWRSRHNNQANAFYYAES
DGYYKQDHWKIFWNGLHHFQQIQQCVAHCTQHPPTLID

Sequences:

>Translated_438_residues
MHANLQTRQIIIRLLSSMASAKEISQYLKRFSQLDAKRFAVVKVGGAVLRDDVDALTSSLSFLQEVGLTPIVLHGAGPQL
DEELTAVGIQKKTVNGFRVTLPETMAIVRKVFHATNLQLIEALQRNGARATSITGGVFEAHYLDQETYGLVGGISAVNIA
PIEASLRAASIPVIASLGETPSGQILNINADVAANELVHVLQPYKIIFLTGTGGLLDADGKIINSINLSTEYEQLIQQPW
VYGGMKLKIEQIKHLLDRLPLESSVSITRPADLAKELFTHKGSGTLIRRGERVIRATTWKDLDLPRLQHLIQSSFRRTLI
PHYFETTPLLRAYVSENYRAAVILTKLGNVPYLDKFAVLDDAQGEGLGRAVWSIMREETPQLFWRSRHNNQANAFYYAES
DGYYKQDHWKIFWNGLHHFQQIQQCVAHCTQHPPTLID
>Mature_438_residues
MHANLQTRQIIIRLLSSMASAKEISQYLKRFSQLDAKRFAVVKVGGAVLRDDVDALTSSLSFLQEVGLTPIVLHGAGPQL
DEELTAVGIQKKTVNGFRVTLPETMAIVRKVFHATNLQLIEALQRNGARATSITGGVFEAHYLDQETYGLVGGISAVNIA
PIEASLRAASIPVIASLGETPSGQILNINADVAANELVHVLQPYKIIFLTGTGGLLDADGKIINSINLSTEYEQLIQQPW
VYGGMKLKIEQIKHLLDRLPLESSVSITRPADLAKELFTHKGSGTLIRRGERVIRATTWKDLDLPRLQHLIQSSFRRTLI
PHYFETTPLLRAYVSENYRAAVILTKLGNVPYLDKFAVLDDAQGEGLGRAVWSIMREETPQLFWRSRHNNQANAFYYAES
DGYYKQDHWKIFWNGLHHFQQIQQCVAHCTQHPPTLID

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI23308587, Length=440, Percent_Identity=32.7272727272727, Blast_Score=213, Evalue=2e-55,
Organism=Escherichia coli, GI145693208, Length=241, Percent_Identity=27.8008298755187, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320913, Length=438, Percent_Identity=41.5525114155251, Blast_Score=338, Evalue=1e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011242
- InterPro:   IPR004662
- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR006855 [H]

Pfam domain/function: PF00696 AA_kinase; PF04768 DUF619 [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 48894; Mature: 48894

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHANLQTRQIIIRLLSSMASAKEISQYLKRFSQLDAKRFAVVKVGGAVLRDDVDALTSSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCHHHHHHHHHHHHHH
SFLQEVGLTPIVLHGAGPQLDEELTAVGIQKKTVNGFRVTLPETMAIVRKVFHATNLQLI
HHHHHCCCCEEEEECCCCCCHHHHHHHCCEEEECCCEEEECHHHHHHHHHHHHHCCHHHH
EALQRNGARATSITGGVFEAHYLDQETYGLVGGISAVNIAPIEASLRAASIPVIASLGET
HHHHHCCCEEEECCCCCHHHHHCCCHHHHHHCCCCEEEEECCHHHHHHHCCCHHEECCCC
PSGQILNINADVAANELVHVLQPYKIIFLTGTGGLLDADGKIINSINLSTEYEQLIQQPW
CCCCEEEECCCHHHHHHHHHHCCEEEEEEECCCCEEECCCCEEEEECCCHHHHHHHHCCC
VYGGMKLKIEQIKHLLDRLPLESSVSITRPADLAKELFTHKGSGTLIRRGERVIRATTWK
CCCCEEEEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEECCCCEEEEEECCC
DLDLPRLQHLIQSSFRRTLIPHYFETTPLLRAYVSENYRAAVILTKLGNVPYLDKFAVLD
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHEEC
DAQGEGLGRAVWSIMREETPQLFWRSRHNNQANAFYYAESDGYYKQDHWKIFWNGLHHFQ
CCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEEECCCCCEECCCHHHHHHHHHHHH
QIQQCVAHCTQHPPTLID
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MHANLQTRQIIIRLLSSMASAKEISQYLKRFSQLDAKRFAVVKVGGAVLRDDVDALTSSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCHHHHHHHHHHHHHH
SFLQEVGLTPIVLHGAGPQLDEELTAVGIQKKTVNGFRVTLPETMAIVRKVFHATNLQLI
HHHHHCCCCEEEEECCCCCCHHHHHHHCCEEEECCCEEEECHHHHHHHHHHHHHCCHHHH
EALQRNGARATSITGGVFEAHYLDQETYGLVGGISAVNIAPIEASLRAASIPVIASLGET
HHHHHCCCEEEECCCCCHHHHHCCCHHHHHHCCCCEEEEECCHHHHHHHCCCHHEECCCC
PSGQILNINADVAANELVHVLQPYKIIFLTGTGGLLDADGKIINSINLSTEYEQLIQQPW
CCCCEEEECCCHHHHHHHHHHCCEEEEEEECCCCEEECCCCEEEEECCCHHHHHHHHCCC
VYGGMKLKIEQIKHLLDRLPLESSVSITRPADLAKELFTHKGSGTLIRRGERVIRATTWK
CCCCEEEEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEECCCCEEEEEECCC
DLDLPRLQHLIQSSFRRTLIPHYFETTPLLRAYVSENYRAAVILTKLGNVPYLDKFAVLD
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHEEC
DAQGEGLGRAVWSIMREETPQLFWRSRHNNQANAFYYAESDGYYKQDHWKIFWNGLHHFQ
CCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEEECCCCCEECCCHHHHHHHHHHHH
QIQQCVAHCTQHPPTLID
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]