Click here to switch to the map view.

The map label for this gene is ggt [H]

Identifier: 182680836

GI number: 182680836

Start: 353172

End: 354983

Strand: Direct

Name: ggt [H]

Synonym: XfasM23_0271

Alternate gene names: 182680836

Gene position: 353172-354983 (Clockwise)

Preceding gene: 182680835

Following gene: 182680837

Centisome position: 13.93

GC content: 54.64

Gene sequence:

>1812_bases
ATGAGTTTATTTCCTCGTTGTTTCTTGTTGCTCTGTGTTTTTTTCTCGCACGTCTCTGCAGAGCAGACAGAGGTAGCACT
GTTACGGGAGGGAGTCGCCAGAGTCCCGCCTGGTGCAGTGATTGCTAGTAGTCATTATTTGGCGACGGATGCTGGGCTGC
AGATTCTGAAGCAGGGTGGGAATGCTTTCGATGCTGCAGTGGCGGTGTCTTCCACGTTGTCGGTGGTTGAACCCATTAGT
TCTGGTTTGGGCGGCGGTGGCTTTTTTCTGCTTCATGATGCCAAGACGGGGCGTGATGTCATGCTGGATGCGCGGGAATA
CGCGCCGGCGTCGGTTAATCTGGGTACGTTTCTAAACAAGGATGGTCAACTGGATCATGACCGTTCGATCAACGGGCCTT
GGTCGGCAGGTATCCCGGGGTTACCGGCAGCACTTGTTGAACTAGCTGAGCATTATGGCAAGTTGCCATTGAGACAAACA
TTGGCACCGGCTATCCGCATTGCGTCTGCGGGGTTTCCTGTGTACAGGCGTATGGTGGAGGGGTATCAGTCGCGCCGTGA
AGTGATGGAGCGTTATCCGGGGACACGTGAAGTCTATCTCCGTGGCGGTAAGCCGATGGATGAGGGTGATATTTTCAAAC
AGCCGGAATTGGCGCGGACTTTGTCGTTATTGGCCAATAAGGGCTTTGATGGTTTTTATAGGGGCGAGACCGCGAAGCGG
TTGCTGGCTGGGGTGAATCAGGCGGGTGGACGTTGGACTGCTGAGGATTTGGCCGGTTATCGGGTCAAGTCGCGTGTTCC
CATCACGTTCGATTATCGAGGGTGGAAGATCACCACTGCGCCGCCGCCGTCTTCTGGCGGTATCGCGTTGGCGGAAATGT
TACAGATCTTGGAAGGTTGGGATCTGGCTCGGCTAGATGACGTGCATCGCGTTCATTTGGTGGTAGAAGCGATGCGCCGT
GCGTATCGGGATCGTACTTTTTTTCTCGGTGATCCCGATTTTGTGTCGATTCCGCAGCGTGTGTTGACGAGTCAGGACTA
TGCGCGTGGTTTGCGTGCGGGGATTAACCCTGAGAAGGCAACGCCTAGCGTGTTGTTATCAGGTCATCCAACGCCATTGG
AGGATGAGGAGACGACGCACTTTTCAATCATTGATGCGGAGGGAAACCGAGTGGGTGCGACGCAAACGGTTAATTTGCTA
TACGGTTCGGGGCTGATTCCGAAGGGAACCGGTGTGTTGCTTAACAATGAGATGGATGATTTTGCACTCCAGCCAGGCGT
GCCAAATGTGTTTGGGGTGATGGGCTATGAGGCGAATGCCCCCAAACCAGGGAAGCGCATGCTCAGCTCAATGACGCCGA
CTTTCCTTGAATCTGCCGATAAAGTGGCGGTGATTGGCACGCCTGGCGGCAGTCGTATTATCACAATGGTGCTGTTGGGG
ATCTTGGGTTACGACGCTGGATTGGACGCGCAACAGGTTGCTGCGTTGCCGCGGTATCACCACCAATGGTTGCCGGACGT
CATTGAGACGGAGGCGGCTACGTTTCCGGCAGAGGTGATCAAGGGATTGGAGACGATGGGGCATACGATCAAGCAGCCAA
GCGATACGGTTGCCGGTGGGCGTGGTTCTAGCCACGTTTGGGGCAATGTGCAGACGGTTGAATGGGATCGTCGTTCTAAT
GTGCTCATTGGCGGTCATGATCCGCGTCATGTTGTGGGCAAAGCGGCCGTTTGGCTCACTGATAAAGCGGTTGTTCTGCC
GCCTATGGACCATTTACCTACGCCGTGCTTGCAGGATTGCCATGCTCAATGA

Upstream 100 bases:

>100_bases
CAGATCCTGGTCTGTTGGAAACGCGGGAGCAACTGCTTAGTAAGTTGCAGCAGTTGCAACGCAACGATCCCGAGTTGTAT
GAAAAGGAATCTCCTGATTT

Downstream 100 bases:

>100_bases
TCGAATTCGGAAGGCTTGCATTGACTCATGAGTAATGCAGCGTATGGCCGCCGTTTGAGTGCCATACGCAGGTTGTGATG
GTGTGATGTGTATTCGCTAA

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MSLFPRCFLLLCVFFSHVSAEQTEVALLREGVARVPPGAVIASSHYLATDAGLQILKQGGNAFDAAVAVSSTLSVVEPIS
SGLGGGGFFLLHDAKTGRDVMLDAREYAPASVNLGTFLNKDGQLDHDRSINGPWSAGIPGLPAALVELAEHYGKLPLRQT
LAPAIRIASAGFPVYRRMVEGYQSRREVMERYPGTREVYLRGGKPMDEGDIFKQPELARTLSLLANKGFDGFYRGETAKR
LLAGVNQAGGRWTAEDLAGYRVKSRVPITFDYRGWKITTAPPPSSGGIALAEMLQILEGWDLARLDDVHRVHLVVEAMRR
AYRDRTFFLGDPDFVSIPQRVLTSQDYARGLRAGINPEKATPSVLLSGHPTPLEDEETTHFSIIDAEGNRVGATQTVNLL
YGSGLIPKGTGVLLNNEMDDFALQPGVPNVFGVMGYEANAPKPGKRMLSSMTPTFLESADKVAVIGTPGGSRIITMVLLG
ILGYDAGLDAQQVAALPRYHHQWLPDVIETEAATFPAEVIKGLETMGHTIKQPSDTVAGGRGSSHVWGNVQTVEWDRRSN
VLIGGHDPRHVVGKAAVWLTDKAVVLPPMDHLPTPCLQDCHAQ

Sequences:

>Translated_603_residues
MSLFPRCFLLLCVFFSHVSAEQTEVALLREGVARVPPGAVIASSHYLATDAGLQILKQGGNAFDAAVAVSSTLSVVEPIS
SGLGGGGFFLLHDAKTGRDVMLDAREYAPASVNLGTFLNKDGQLDHDRSINGPWSAGIPGLPAALVELAEHYGKLPLRQT
LAPAIRIASAGFPVYRRMVEGYQSRREVMERYPGTREVYLRGGKPMDEGDIFKQPELARTLSLLANKGFDGFYRGETAKR
LLAGVNQAGGRWTAEDLAGYRVKSRVPITFDYRGWKITTAPPPSSGGIALAEMLQILEGWDLARLDDVHRVHLVVEAMRR
AYRDRTFFLGDPDFVSIPQRVLTSQDYARGLRAGINPEKATPSVLLSGHPTPLEDEETTHFSIIDAEGNRVGATQTVNLL
YGSGLIPKGTGVLLNNEMDDFALQPGVPNVFGVMGYEANAPKPGKRMLSSMTPTFLESADKVAVIGTPGGSRIITMVLLG
ILGYDAGLDAQQVAALPRYHHQWLPDVIETEAATFPAEVIKGLETMGHTIKQPSDTVAGGRGSSHVWGNVQTVEWDRRSN
VLIGGHDPRHVVGKAAVWLTDKAVVLPPMDHLPTPCLQDCHAQ
>Mature_602_residues
SLFPRCFLLLCVFFSHVSAEQTEVALLREGVARVPPGAVIASSHYLATDAGLQILKQGGNAFDAAVAVSSTLSVVEPISS
GLGGGGFFLLHDAKTGRDVMLDAREYAPASVNLGTFLNKDGQLDHDRSINGPWSAGIPGLPAALVELAEHYGKLPLRQTL
APAIRIASAGFPVYRRMVEGYQSRREVMERYPGTREVYLRGGKPMDEGDIFKQPELARTLSLLANKGFDGFYRGETAKRL
LAGVNQAGGRWTAEDLAGYRVKSRVPITFDYRGWKITTAPPPSSGGIALAEMLQILEGWDLARLDDVHRVHLVVEAMRRA
YRDRTFFLGDPDFVSIPQRVLTSQDYARGLRAGINPEKATPSVLLSGHPTPLEDEETTHFSIIDAEGNRVGATQTVNLLY
GSGLIPKGTGVLLNNEMDDFALQPGVPNVFGVMGYEANAPKPGKRMLSSMTPTFLESADKVAVIGTPGGSRIITMVLLGI
LGYDAGLDAQQVAALPRYHHQWLPDVIETEAATFPAEVIKGLETMGHTIKQPSDTVAGGRGSSHVWGNVQTVEWDRRSNV
LIGGHDPRHVVGKAAVWLTDKAVVLPPMDHLPTPCLQDCHAQ

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=514, Percent_Identity=33.4630350194552, Blast_Score=240, Evalue=3e-63,
Organism=Homo sapiens, GI73915090, Length=514, Percent_Identity=33.4630350194552, Blast_Score=240, Evalue=3e-63,
Organism=Homo sapiens, GI73915096, Length=514, Percent_Identity=33.4630350194552, Blast_Score=240, Evalue=3e-63,
Organism=Homo sapiens, GI73915094, Length=514, Percent_Identity=33.4630350194552, Blast_Score=240, Evalue=3e-63,
Organism=Homo sapiens, GI113429324, Length=514, Percent_Identity=31.7120622568093, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI113429326, Length=519, Percent_Identity=31.4065510597302, Blast_Score=207, Evalue=3e-53,
Organism=Homo sapiens, GI109148539, Length=551, Percent_Identity=30.8529945553539, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI153266901, Length=522, Percent_Identity=29.5019157088123, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI153266885, Length=520, Percent_Identity=29.0384615384615, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI153266907, Length=516, Percent_Identity=26.937984496124, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI30581157, Length=201, Percent_Identity=35.8208955223881, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI30581155, Length=201, Percent_Identity=35.8208955223881, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI218505805, Length=198, Percent_Identity=34.8484848484849, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI310124095, Length=199, Percent_Identity=31.1557788944724, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789856, Length=497, Percent_Identity=40.0402414486922, Blast_Score=381, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI212646519, Length=514, Percent_Identity=32.8793774319066, Blast_Score=212, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI72000294, Length=514, Percent_Identity=32.8793774319066, Blast_Score=212, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17506189, Length=560, Percent_Identity=30, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI193208247, Length=508, Percent_Identity=31.1023622047244, Blast_Score=195, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI193208245, Length=508, Percent_Identity=31.1023622047244, Blast_Score=195, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17542894, Length=545, Percent_Identity=29.5412844036697, Blast_Score=189, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17564448, Length=406, Percent_Identity=24.384236453202, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI72001495, Length=225, Percent_Identity=26.2222222222222, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI72001497, Length=225, Percent_Identity=26.2222222222222, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323330, Length=544, Percent_Identity=28.8602941176471, Blast_Score=150, Evalue=8e-37,
Organism=Drosophila melanogaster, GI161077878, Length=532, Percent_Identity=29.5112781954887, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI45551474, Length=532, Percent_Identity=29.5112781954887, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI161077880, Length=532, Percent_Identity=29.5112781954887, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24642670, Length=532, Percent_Identity=29.5112781954887, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24642666, Length=532, Percent_Identity=29.5112781954887, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI18859893, Length=511, Percent_Identity=31.8982387475538, Blast_Score=189, Evalue=6e-48,
Organism=Drosophila melanogaster, GI161077496, Length=510, Percent_Identity=29.6078431372549, Blast_Score=181, Evalue=2e-45,
Organism=Drosophila melanogaster, GI18859741, Length=518, Percent_Identity=26.6409266409266, Blast_Score=149, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 65235; Mature: 65104

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFPRCFLLLCVFFSHVSAEQTEVALLREGVARVPPGAVIASSHYLATDAGLQILKQGG
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEECCCEEEHHHHHHHHHCCC
NAFDAAVAVSSTLSVVEPISSGLGGGGFFLLHDAKTGRDVMLDAREYAPASVNLGTFLNK
CHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEHHHCCCCCCCHHHHCCC
DGQLDHDRSINGPWSAGIPGLPAALVELAEHYGKLPLRQTLAPAIRIASAGFPVYRRMVE
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHH
GYQSRREVMERYPGTREVYLRGGKPMDEGDIFKQPELARTLSLLANKGFDGFYRGETAKR
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHH
LLAGVNQAGGRWTAEDLAGYRVKSRVPITFDYRGWKITTAPPPSSGGIALAEMLQILEGW
HHHHHHCCCCEEEHHHHCCCEECCCCCEEEECCCEEEECCCCCCCCCHHHHHHHHHHCCC
DLARLDDVHRVHLVVEAMRRAYRDRTFFLGDPDFVSIPQRVLTSQDYARGLRAGINPEKA
CCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCHHHHHHHHCCCCCCCC
TPSVLLSGHPTPLEDEETTHFSIIDAEGNRVGATQTVNLLYGSGLIPKGTGVLLNNEMDD
CCCEEECCCCCCCCCCCCCEEEEEECCCCEECCCEEEEEEECCCCCCCCCCEEECCCCCH
FALQPGVPNVFGVMGYEANAPKPGKRMLSSMTPTFLESADKVAVIGTPGGSRIITMVLLG
HCCCCCCCHHHEECCCCCCCCCHHHHHHHHCCCHHHCCCCCEEEEECCCCHHHHHHHHHH
ILGYDAGLDAQQVAALPRYHHQWLPDVIETEAATFPAEVIKGLETMGHTIKQPSDTVAGG
HHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCC
RGSSHVWGNVQTVEWDRRSNVLIGGHDPRHVVGKAAVWLTDKAVVLPPMDHLPTPCLQDC
CCCCCCCCCEEEEEECCCCCEEECCCCCHHHHCCEEEEEECCEEEECCHHHCCCHHHHHH
HAQ
CCC
>Mature Secondary Structure 
SLFPRCFLLLCVFFSHVSAEQTEVALLREGVARVPPGAVIASSHYLATDAGLQILKQGG
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEECCCEEEHHHHHHHHHCCC
NAFDAAVAVSSTLSVVEPISSGLGGGGFFLLHDAKTGRDVMLDAREYAPASVNLGTFLNK
CHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEHHHCCCCCCCHHHHCCC
DGQLDHDRSINGPWSAGIPGLPAALVELAEHYGKLPLRQTLAPAIRIASAGFPVYRRMVE
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHH
GYQSRREVMERYPGTREVYLRGGKPMDEGDIFKQPELARTLSLLANKGFDGFYRGETAKR
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHH
LLAGVNQAGGRWTAEDLAGYRVKSRVPITFDYRGWKITTAPPPSSGGIALAEMLQILEGW
HHHHHHCCCCEEEHHHHCCCEECCCCCEEEECCCEEEECCCCCCCCCHHHHHHHHHHCCC
DLARLDDVHRVHLVVEAMRRAYRDRTFFLGDPDFVSIPQRVLTSQDYARGLRAGINPEKA
CCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCHHHHHHHHCCCCCCCC
TPSVLLSGHPTPLEDEETTHFSIIDAEGNRVGATQTVNLLYGSGLIPKGTGVLLNNEMDD
CCCEEECCCCCCCCCCCCCEEEEEECCCCEECCCEEEEEEECCCCCCCCCCEEECCCCCH
FALQPGVPNVFGVMGYEANAPKPGKRMLSSMTPTFLESADKVAVIGTPGGSRIITMVLLG
HCCCCCCCHHHEECCCCCCCCCHHHHHHHHCCCHHHCCCCCEEEEECCCCHHHHHHHHHH
ILGYDAGLDAQQVAALPRYHHQWLPDVIETEAATFPAEVIKGLETMGHTIKQPSDTVAGG
HHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCC
RGSSHVWGNVQTVEWDRRSNVLIGGHDPRHVVGKAAVWLTDKAVVLPPMDHLPTPCLQDC
CCCCCCCCCEEEEEECCCCCEEECCCCCHHHHCCEEEEEECCEEEECCHHHCCCHHHHHH
HAQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7765305 [H]