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The map label for this gene is nuoG [H]

Identifier: 182680811

GI number: 182680811

Start: 322451

End: 324685

Strand: Direct

Name: nuoG [H]

Synonym: XfasM23_0246

Alternate gene names: 182680811

Gene position: 322451-324685 (Clockwise)

Preceding gene: 182680810

Following gene: 182680812

Centisome position: 12.72

GC content: 55.79

Gene sequence:

>2235_bases
ATGAGTGACCAATCTGTGAATCCTGAGGTGCGGCCTGATCGTGTCACCATTGAAATTGATGGCCAGAATTTAGTTGTACC
GAAAGGTTCAATGATTATTCAGGCTGCAGATAACGCTGGTATTCCGATCCCGCGTTTTTGTTACCACGAGAAGTTGCCAA
TCGCGGCCAATTGCAGAATGTGTCTTGTCGATGTCGAGAAGGTGCCGAAGCCTTTGCCAGCCTGTGCTACGCCGGTGATG
GAGGGGATGAAAGTCCGCACCCGCAGTGAAAAAGCCCTGCAATATCAGCGTAGCGTGATGGAGTTCTTGCTCATCAATCA
TCCCCTGGATTGTCCGATTTGTGATCAGGGAGGCGAGTGCGAGTTGCAGGATGTTTCAATGGGCTATGGTCGCTCGGTCA
GCCGCTTTCATGAGCGTAAACGCGTGGTACCGGATGAGGACATTGGTCCGTTGGTCGCTACCGAGATGACCCGCTGTATT
CAATGCACGCGTTGTGTGCGTTTTACCGCTGACATTGCTGGTACCTATGAGTTGGGCGGTATGTACCGTGGAGAGAATCT
GCAAATCGGTACTTATGACGGTAAACCACTTATTACTGAGTTATCTGGGAACGTGGTCGATGTGTGCCCGGTCGGTGCAT
TGACGAACAAGGTATTTCAGTTTCGTGCTAGACCGTGGGAATTAATGGCCTACCAGTCGTTGGGGTATCACGATGCGATG
GGTTCCAACTTATTTCTGCATGTGCGTCAGGGCGAAGTGTTACGTACGGTGCCGCGTGACAATGAGTATGTGAACGAGTG
TTGGTTGTCTGATCGTGATCGTTATTCGCATCAGGGGTTGTACGCGGCGGATCGTGCGGTCAAGCCGCTAAAGAAGGTTG
GTGACCAGTGGTTGGAAGTGAGTTGGGCCGAGGGTGTGTCCGCTGCCGCTGAGATCTTGAGTGCGCATCGTGGCGATGCG
CTTGGTGTTTTGGTGCATCCTGCTACGTCGAACGAAGAGGGGGCATTGTTGGCACGTCTGGCAGCGGGTCTGGGCACCGG
TCACCTTGATCATCGGATCTTCAACCGTGATTTTTCTGATGTTGCTGTGGCCGAGCCGTTTGCATTGCCGTTGGCAGAGA
TCGGCAACGCCGATCTGGTCGTCTTATTCGGAAGCAACATACGTCAGGAGTTACCGTTGTTGCATGCACGCCTCCGCAAA
GCGGTCACTTGCAACGGCGCCAAGGTGTACGCGGTAAATCCGGTCGATTTTGACTTCACTTTCTCGCTGACTGGGAAGTC
CATCGTTCCTCCGTCGCAGTTAGCCAATGCGTTGACCGATGCGGCTTTGCTCAATGCGGCGAAAGCGGCTGCCCGTGTGG
TCATTGTGGTCGGTGCACTGGCCGAGAATCACCCGCAAGCAGCCACGTTGCGGGCGGCGGCGCGTCAGTTCGCTGAGACG
ACCGGTGCGGCCTTGTGCCGCATCCCGCAAGGGGCTAATTCGATTGGACTTACCCAGCACGGTGTGTTGCCGACAGGTCG
TGATGCTGCTGCGATGCTTGTCGAGCCTTGTCAGGCTTATGTGTTGTACGGTATTGAGCCGGGCTTGGACTTTGCCGACA
CGGCGACCGCGCGTCAGGTACTGCATGGTGCCAAGGTGGTCGCGTTCAGTCATTTCGCTTGTGTCTCAACCCGTGATGTC
GCGGATGTCATCTTGCCTATTGGTTTATTACCTGAGATTGATGGGACATTGACTAATCTTGATGGTCGCACTCAGGCGGC
TAAGCCAGGCGGCAAATTACCGCTTGAGGCCCGTGAGGGATGGCGTGTGCTGCGTGCCTTGGGAGGTGAGTTGGGGCTAT
CCGGTTTTGATTTTCTCGATTTGGCGGGTTTGCGTGCGCAGTTGCGGCCGCACCCCGTGGTTCCTTCGACATCGGCACAG
CCGATTGCAGCGCAGGAGGGGTTGGAAGTGGCGGCGACACCGGCGATCTATCGTACGGATGCCGTCGTACGTCGTGCTGC
TGCATTGCAGGCGCATCCGCTGAATGTTGCTCCAGCCCTGGCGTTACATCCAGAGCAGGCGAAGCAATTGCAAGTGGTCG
CTGGCCAGATGGTTAAAGTGAGTACGGCTGCTGGCAAAGCGACGCTGCCAGTGGTGTTAGACACGCGTGTCGCCTTGGGT
ACGGTCTGGATCGAAACGGGTCACGGTGCCACCGCACCAATCGGTGCTGGTCGCGTCACGATGGTGGCTGTATGA

Upstream 100 bases:

>100_bases
CTTGGCCAATCCAAGGGTTCCTGCGCCAATTCTGGGATGAATTTGAGTACTACATTGTTCATGGTCGGTCGATTGTGGAT
GACAAGGCGAGAGTGGCTGC

Downstream 100 bases:

>100_bases
ATACATGGTTCTTGAATGTGGTTGATCCGTTGCACCAATGGTTTCTCGGGTTTGGAGACATTGGTGTCGTGTTGTGGACC
GTCTTGAAGATACTCATGAT

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 744; Mature: 743

Protein sequence:

>744_residues
MSDQSVNPEVRPDRVTIEIDGQNLVVPKGSMIIQAADNAGIPIPRFCYHEKLPIAANCRMCLVDVEKVPKPLPACATPVM
EGMKVRTRSEKALQYQRSVMEFLLINHPLDCPICDQGGECELQDVSMGYGRSVSRFHERKRVVPDEDIGPLVATEMTRCI
QCTRCVRFTADIAGTYELGGMYRGENLQIGTYDGKPLITELSGNVVDVCPVGALTNKVFQFRARPWELMAYQSLGYHDAM
GSNLFLHVRQGEVLRTVPRDNEYVNECWLSDRDRYSHQGLYAADRAVKPLKKVGDQWLEVSWAEGVSAAAEILSAHRGDA
LGVLVHPATSNEEGALLARLAAGLGTGHLDHRIFNRDFSDVAVAEPFALPLAEIGNADLVVLFGSNIRQELPLLHARLRK
AVTCNGAKVYAVNPVDFDFTFSLTGKSIVPPSQLANALTDAALLNAAKAAARVVIVVGALAENHPQAATLRAAARQFAET
TGAALCRIPQGANSIGLTQHGVLPTGRDAAAMLVEPCQAYVLYGIEPGLDFADTATARQVLHGAKVVAFSHFACVSTRDV
ADVILPIGLLPEIDGTLTNLDGRTQAAKPGGKLPLEAREGWRVLRALGGELGLSGFDFLDLAGLRAQLRPHPVVPSTSAQ
PIAAQEGLEVAATPAIYRTDAVVRRAAALQAHPLNVAPALALHPEQAKQLQVVAGQMVKVSTAAGKATLPVVLDTRVALG
TVWIETGHGATAPIGAGRVTMVAV

Sequences:

>Translated_744_residues
MSDQSVNPEVRPDRVTIEIDGQNLVVPKGSMIIQAADNAGIPIPRFCYHEKLPIAANCRMCLVDVEKVPKPLPACATPVM
EGMKVRTRSEKALQYQRSVMEFLLINHPLDCPICDQGGECELQDVSMGYGRSVSRFHERKRVVPDEDIGPLVATEMTRCI
QCTRCVRFTADIAGTYELGGMYRGENLQIGTYDGKPLITELSGNVVDVCPVGALTNKVFQFRARPWELMAYQSLGYHDAM
GSNLFLHVRQGEVLRTVPRDNEYVNECWLSDRDRYSHQGLYAADRAVKPLKKVGDQWLEVSWAEGVSAAAEILSAHRGDA
LGVLVHPATSNEEGALLARLAAGLGTGHLDHRIFNRDFSDVAVAEPFALPLAEIGNADLVVLFGSNIRQELPLLHARLRK
AVTCNGAKVYAVNPVDFDFTFSLTGKSIVPPSQLANALTDAALLNAAKAAARVVIVVGALAENHPQAATLRAAARQFAET
TGAALCRIPQGANSIGLTQHGVLPTGRDAAAMLVEPCQAYVLYGIEPGLDFADTATARQVLHGAKVVAFSHFACVSTRDV
ADVILPIGLLPEIDGTLTNLDGRTQAAKPGGKLPLEAREGWRVLRALGGELGLSGFDFLDLAGLRAQLRPHPVVPSTSAQ
PIAAQEGLEVAATPAIYRTDAVVRRAAALQAHPLNVAPALALHPEQAKQLQVVAGQMVKVSTAAGKATLPVVLDTRVALG
TVWIETGHGATAPIGAGRVTMVAV
>Mature_743_residues
SDQSVNPEVRPDRVTIEIDGQNLVVPKGSMIIQAADNAGIPIPRFCYHEKLPIAANCRMCLVDVEKVPKPLPACATPVME
GMKVRTRSEKALQYQRSVMEFLLINHPLDCPICDQGGECELQDVSMGYGRSVSRFHERKRVVPDEDIGPLVATEMTRCIQ
CTRCVRFTADIAGTYELGGMYRGENLQIGTYDGKPLITELSGNVVDVCPVGALTNKVFQFRARPWELMAYQSLGYHDAMG
SNLFLHVRQGEVLRTVPRDNEYVNECWLSDRDRYSHQGLYAADRAVKPLKKVGDQWLEVSWAEGVSAAAEILSAHRGDAL
GVLVHPATSNEEGALLARLAAGLGTGHLDHRIFNRDFSDVAVAEPFALPLAEIGNADLVVLFGSNIRQELPLLHARLRKA
VTCNGAKVYAVNPVDFDFTFSLTGKSIVPPSQLANALTDAALLNAAKAAARVVIVVGALAENHPQAATLRAAARQFAETT
GAALCRIPQGANSIGLTQHGVLPTGRDAAAMLVEPCQAYVLYGIEPGLDFADTATARQVLHGAKVVAFSHFACVSTRDVA
DVILPIGLLPEIDGTLTNLDGRTQAAKPGGKLPLEAREGWRVLRALGGELGLSGFDFLDLAGLRAQLRPHPVVPSTSAQP
IAAQEGLEVAATPAIYRTDAVVRRAAALQAHPLNVAPALALHPEQAKQLQVVAGQMVKVSTAAGKATLPVVLDTRVALGT
VWIETGHGATAPIGAGRVTMVAV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=625, Percent_Identity=38.08, Blast_Score=395, Evalue=1e-110,
Organism=Escherichia coli, GI145693161, Length=410, Percent_Identity=30, Blast_Score=205, Evalue=9e-54,
Organism=Caenorhabditis elegans, GI17565758, Length=646, Percent_Identity=36.8421052631579, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI32566231, Length=600, Percent_Identity=37.1666666666667, Blast_Score=356, Evalue=2e-98,
Organism=Caenorhabditis elegans, GI193209088, Length=254, Percent_Identity=53.9370078740158, Blast_Score=295, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24640559, Length=644, Percent_Identity=38.6645962732919, Blast_Score=385, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24640557, Length=644, Percent_Identity=38.6645962732919, Blast_Score=385, Evalue=1e-107,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 79656; Mature: 79525

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQSVNPEVRPDRVTIEIDGQNLVVPKGSMIIQAADNAGIPIPRFCYHEKLPIAANCRM
CCCCCCCCCCCCCEEEEEECCCEEEECCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCE
CLVDVEKVPKPLPACATPVMEGMKVRTRSEKALQYQRSVMEFLLINHPLDCPICDQGGEC
EEEEHHHCCCCCCHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ELQDVSMGYGRSVSRFHERKRVVPDEDIGPLVATEMTRCIQCTRCVRFTADIAGTYELGG
EEEECCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
MYRGENLQIGTYDGKPLITELSGNVVDVCPVGALTNKVFQFRARPWELMAYQSLGYHDAM
EEECCCEEEECCCCCEEEEECCCCEEEECCCCHHHHHHHHHCCCCEEEEEEHHCCCHHCC
GSNLFLHVRQGEVLRTVPRDNEYVNECWLSDRDRYSHQGLYAADRAVKPLKKVGDQWLEV
CCCEEEEEECCCEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCHHHEEE
SWAEGVSAAAEILSAHRGDALGVLVHPATSNEEGALLARLAAGLGTGHLDHRIFNRDFSD
EHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCC
VAVAEPFALPLAEIGNADLVVLFGSNIRQELPLLHARLRKAVTCNGAKVYAVNPVDFDFT
HHHCCCCCCCHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHEEECCEEEEEECCCCEEEE
FSLTGKSIVPPSQLANALTDAALLNAAKAAARVVIVVGALAENHPQAATLRAAARQFAET
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHCCCCHHHHHHHHHHHHHHH
TGAALCRIPQGANSIGLTQHGVLPTGRDAAAMLVEPCQAYVLYGIEPGLDFADTATARQV
CCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHH
LHGAKVVAFSHFACVSTRDVADVILPIGLLPEIDGTLTNLDGRTQAAKPGGKLPLEAREG
HHCCEEEEEEHEEEECCCHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCCHHHH
WRVLRALGGELGLSGFDFLDLAGLRAQLRPHPVVPSTSAQPIAAQEGLEVAATPAIYRTD
HHHHHHHCHHCCCCCCCHHHHHCHHHHCCCCCCCCCCCCCCCHHHCCCEEEECCCHHHHH
AVVRRAAALQAHPLNVAPALALHPEQAKQLQVVAGQMVKVSTAAGKATLPVVLDTRVALG
HHHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHCCEEEEEECCCCEEEEEEEECCEEEE
TVWIETGHGATAPIGAGRVTMVAV
EEEEECCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
SDQSVNPEVRPDRVTIEIDGQNLVVPKGSMIIQAADNAGIPIPRFCYHEKLPIAANCRM
CCCCCCCCCCCCEEEEEECCCEEEECCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCE
CLVDVEKVPKPLPACATPVMEGMKVRTRSEKALQYQRSVMEFLLINHPLDCPICDQGGEC
EEEEHHHCCCCCCHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ELQDVSMGYGRSVSRFHERKRVVPDEDIGPLVATEMTRCIQCTRCVRFTADIAGTYELGG
EEEECCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
MYRGENLQIGTYDGKPLITELSGNVVDVCPVGALTNKVFQFRARPWELMAYQSLGYHDAM
EEECCCEEEECCCCCEEEEECCCCEEEECCCCHHHHHHHHHCCCCEEEEEEHHCCCHHCC
GSNLFLHVRQGEVLRTVPRDNEYVNECWLSDRDRYSHQGLYAADRAVKPLKKVGDQWLEV
CCCEEEEEECCCEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCHHHEEE
SWAEGVSAAAEILSAHRGDALGVLVHPATSNEEGALLARLAAGLGTGHLDHRIFNRDFSD
EHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCC
VAVAEPFALPLAEIGNADLVVLFGSNIRQELPLLHARLRKAVTCNGAKVYAVNPVDFDFT
HHHCCCCCCCHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHEEECCEEEEEECCCCEEEE
FSLTGKSIVPPSQLANALTDAALLNAAKAAARVVIVVGALAENHPQAATLRAAARQFAET
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHCCCCHHHHHHHHHHHHHHH
TGAALCRIPQGANSIGLTQHGVLPTGRDAAAMLVEPCQAYVLYGIEPGLDFADTATARQV
CCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHH
LHGAKVVAFSHFACVSTRDVADVILPIGLLPEIDGTLTNLDGRTQAAKPGGKLPLEAREG
HHCCEEEEEEHEEEECCCHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCCHHHH
WRVLRALGGELGLSGFDFLDLAGLRAQLRPHPVVPSTSAQPIAAQEGLEVAATPAIYRTD
HHHHHHHCHHCCCCCCCHHHHHCHHHHCCCCCCCCCCCCCCCHHHCCCEEEECCCHHHHH
AVVRRAAALQAHPLNVAPALALHPEQAKQLQVVAGQMVKVSTAAGKATLPVVLDTRVALG
HHHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHCCEEEEEECCCCEEEEEEEECCEEEE
TVWIETGHGATAPIGAGRVTMVAV
EEEEECCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]