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The map label for this gene is nuoE [H]

Identifier: 182680809

GI number: 182680809

Start: 320588

End: 321115

Strand: Direct

Name: nuoE [H]

Synonym: XfasM23_0244

Alternate gene names: 182680809

Gene position: 320588-321115 (Clockwise)

Preceding gene: 182680808

Following gene: 182680810

Centisome position: 12.64

GC content: 51.52

Gene sequence:

>528_bases
ATGAAGGCGACAAAGAGTTTTGAACTGGTGCGTGATGTGGATCCCCAGGTGGTATTGGGTGACCGCACGCGGGCTCACAT
TGATCATTGGCTTGCCAAGTTTCCAGCGGATCAGAAGCGATCAGCCTTGTTGCAGGGGCTGTATGCCGCGCAGGAGCAAA
ATCAGGGTTGGTTGACGGATGAGCTCATCGCCGCTGTGGCCAAATATCTGGATATTCCGTCCGTATGGGCTTATGAGGTT
GCTACTTTCTACTCAATGTTTGAGACGCGGAAGGTTGGCCGCCATAATGTTGCTTTCTGCACCAATGTCAGTTGTTGGCT
CAACGGTGCTGAGGATTTGGTGAGCTATGCGGAGGAAAAACTAGGTTGCAAGCTTGGCCAATCCACTGCTGACGGCCGTG
TTTACCTCAAGTGTGAGGAAGAATGCCTTGCTGCTTGTGCTGGTGCTCCGATGATGGTGATTAACGGTCATTATCATGAG
CGTCTGACCAAGGAGAAGGTTGACCAGTTGTTAGACGGCTTGGAGTAA

Upstream 100 bases:

>100_bases
CGCACTTGTCCTCAATGGATGCCGTGGTGCGTGGCTATATGTTGGCCGATGTTGTGGCCATGATTGGTACATATGATTTA
GTGTTTGGTGAGGTCGACCG

Downstream 100 bases:

>100_bases
CGTCATGGGACATCCTCACGTATCCAAGGGACCGGTTGGCCCGGCACCTCAGCCGCACCAAGTGATCTATACCACGTTGC
ATTATGAAATTCCTTGGTCG

Product: NADH dehydrogenase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MKATKSFELVRDVDPQVVLGDRTRAHIDHWLAKFPADQKRSALLQGLYAAQEQNQGWLTDELIAAVAKYLDIPSVWAYEV
ATFYSMFETRKVGRHNVAFCTNVSCWLNGAEDLVSYAEEKLGCKLGQSTADGRVYLKCEEECLAACAGAPMMVINGHYHE
RLTKEKVDQLLDGLE

Sequences:

>Translated_175_residues
MKATKSFELVRDVDPQVVLGDRTRAHIDHWLAKFPADQKRSALLQGLYAAQEQNQGWLTDELIAAVAKYLDIPSVWAYEV
ATFYSMFETRKVGRHNVAFCTNVSCWLNGAEDLVSYAEEKLGCKLGQSTADGRVYLKCEEECLAACAGAPMMVINGHYHE
RLTKEKVDQLLDGLE
>Mature_175_residues
MKATKSFELVRDVDPQVVLGDRTRAHIDHWLAKFPADQKRSALLQGLYAAQEQNQGWLTDELIAAVAKYLDIPSVWAYEV
ATFYSMFETRKVGRHNVAFCTNVSCWLNGAEDLVSYAEEKLGCKLGQSTADGRVYLKCEEECLAACAGAPMMVINGHYHE
RLTKEKVDQLLDGLE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=149, Percent_Identity=36.9127516778523, Blast_Score=116, Evalue=1e-26,
Organism=Escherichia coli, GI1788621, Length=151, Percent_Identity=37.0860927152318, Blast_Score=95, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17561328, Length=155, Percent_Identity=41.2903225806452, Blast_Score=116, Evalue=5e-27,
Organism=Drosophila melanogaster, GI18859877, Length=152, Percent_Identity=36.8421052631579, Blast_Score=116, Evalue=8e-27,
Organism=Drosophila melanogaster, GI21355353, Length=149, Percent_Identity=33.5570469798658, Blast_Score=90, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 19646; Mature: 19646

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKATKSFELVRDVDPQVVLGDRTRAHIDHWLAKFPADQKRSALLQGLYAAQEQNQGWLTD
CCCCHHHHHHHCCCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHH
ELIAAVAKYLDIPSVWAYEVATFYSMFETRKVGRHNVAFCTNVSCWLNGAEDLVSYAEEK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHCCHHHHHHHHHHH
LGCKLGQSTADGRVYLKCEEECLAACAGAPMMVINGHYHERLTKEKVDQLLDGLE
HHHHCCCCCCCCEEEEEECHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKATKSFELVRDVDPQVVLGDRTRAHIDHWLAKFPADQKRSALLQGLYAAQEQNQGWLTD
CCCCHHHHHHHCCCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHH
ELIAAVAKYLDIPSVWAYEVATFYSMFETRKVGRHNVAFCTNVSCWLNGAEDLVSYAEEK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHCCHHHHHHHHHHH
LGCKLGQSTADGRVYLKCEEECLAACAGAPMMVINGHYHERLTKEKVDQLLDGLE
HHHHCCCCCCCCEEEEEECHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA