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The map label for this gene is etfA [H]

Identifier: 182680764

GI number: 182680764

Start: 263372

End: 264322

Strand: Reverse

Name: etfA [H]

Synonym: XfasM23_0193

Alternate gene names: 182680764

Gene position: 264322-263372 (Counterclockwise)

Preceding gene: 182680765

Following gene: 182680762

Centisome position: 10.42

GC content: 55.52

Gene sequence:

>951_bases
ATGACCAAGCTGCTTATCATCGCCGAACACTTGGATGGTCAACTCAACGCGGCAACGGCTAAAACTGTCAGTGCAGCGCT
TGCACTATCACCCGAAGCCATCGACATCGCCGTACTAGCTGCCATCCCGGACAGCGTCGCCGCGCAAGCCCAACACATTG
CCGGTGTCACACGCGTACTCACCATTGCCAACCCTGCCAACAAGCACCCGATTGCACAAATACTAGCCCCACAAATCGCC
GCACTCGTCCAAACCAACAGCTACACCCACGTGTTCGGACCCTCGACAACGTTTGGCAAAGACCTCATGCCCGTCGTGGC
GGCGCTACTCAACGTCAACCAAATTTCGGACCTAATGGGCCTCCAAGACGCCTACACCTTCACCCGTCCCATCTACGCTG
GTAACGCAATCATCACGGTGAAAGCACCTACTGATCAGATCGTCGTTGCCACCATACGCACCGCATCATGGCCAGAAGCC
GCAAAAGGCGGCAACGCCACCATAGAAACAGTAACGGTCTCAGCACACTTACCAAACCACACCCGCTTTCTCAGCCTGGA
TGTGCACACCTGCGACCGTCCAGACCTACAAAATGCCAAACGTGTGGTGGCTGGTGGCCGTGGCCTTGGTTCCCCAGAAA
ACTTCAAATTGATCTATACACTCGCTGACACACTCGGTGCGGCAGTCGGTGCTTCACGTGCTGCAGTGGACGCCGGTTAC
GTACCGAACGAACTGCAAATCGGCCAAACCGGAAAAATCATCGCCCCGGATTTGTACATCGCCATCGGCATTAGCGGTGC
CATCCAGCACCTGACCGGCATCAAAGATGCAGGGACCATTGTCGCCATCAATCAAGACGCCGACGCGCCAATCTTCGAGA
TCGCCGACATCGGTTTAGTCGGCGACCTGTTTCAACTCATCCCAGAACTGGACATGGCTCTCAACAAATAA

Upstream 100 bases:

>100_bases
AAACCACACATTACGCCCCCCCCAAAAAACGCAACCAAGGCGTGATGGTGAAAAACGTCACCGAACTGGTGACCCTCCTC
AAGAACCAAGGAGCCCTATC

Downstream 100 bases:

>100_bases
GCTTCCAGAAAGAGCCAAAATCTGGGAGCTCCTCCATCGCCAACAACGCTGTGAAATAACCTTTCATGTGCTGGTGCATC
GACCAAAGCTCACTGGATAT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTKLLIIAEHLDGQLNAATAKTVSAALALSPEAIDIAVLAAIPDSVAAQAQHIAGVTRVLTIANPANKHPIAQILAPQIA
ALVQTNSYTHVFGPSTTFGKDLMPVVAALLNVNQISDLMGLQDAYTFTRPIYAGNAIITVKAPTDQIVVATIRTASWPEA
AKGGNATIETVTVSAHLPNHTRFLSLDVHTCDRPDLQNAKRVVAGGRGLGSPENFKLIYTLADTLGAAVGASRAAVDAGY
VPNELQIGQTGKIIAPDLYIAIGISGAIQHLTGIKDAGTIVAINQDADAPIFEIADIGLVGDLFQLIPELDMALNK

Sequences:

>Translated_316_residues
MTKLLIIAEHLDGQLNAATAKTVSAALALSPEAIDIAVLAAIPDSVAAQAQHIAGVTRVLTIANPANKHPIAQILAPQIA
ALVQTNSYTHVFGPSTTFGKDLMPVVAALLNVNQISDLMGLQDAYTFTRPIYAGNAIITVKAPTDQIVVATIRTASWPEA
AKGGNATIETVTVSAHLPNHTRFLSLDVHTCDRPDLQNAKRVVAGGRGLGSPENFKLIYTLADTLGAAVGASRAAVDAGY
VPNELQIGQTGKIIAPDLYIAIGISGAIQHLTGIKDAGTIVAINQDADAPIFEIADIGLVGDLFQLIPELDMALNK
>Mature_315_residues
TKLLIIAEHLDGQLNAATAKTVSAALALSPEAIDIAVLAAIPDSVAAQAQHIAGVTRVLTIANPANKHPIAQILAPQIAA
LVQTNSYTHVFGPSTTFGKDLMPVVAALLNVNQISDLMGLQDAYTFTRPIYAGNAIITVKAPTDQIVVATIRTASWPEAA
KGGNATIETVTVSAHLPNHTRFLSLDVHTCDRPDLQNAKRVVAGGRGLGSPENFKLIYTLADTLGAAVGASRAAVDAGYV
PNELQIGQTGKIIAPDLYIAIGISGAIQHLTGIKDAGTIVAINQDADAPIFEIADIGLVGDLFQLIPELDMALNK

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=313, Percent_Identity=47.9233226837061, Blast_Score=271, Evalue=4e-73,
Organism=Homo sapiens, GI189181759, Length=273, Percent_Identity=49.8168498168498, Blast_Score=257, Evalue=8e-69,
Organism=Escherichia coli, GI1787990, Length=123, Percent_Identity=45.5284552845528, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786226, Length=232, Percent_Identity=34.9137931034483, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI87082157, Length=219, Percent_Identity=34.2465753424658, Blast_Score=88, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17506929, Length=314, Percent_Identity=48.0891719745223, Blast_Score=275, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6325261, Length=245, Percent_Identity=44.8979591836735, Blast_Score=209, Evalue=4e-55,
Organism=Drosophila melanogaster, GI17136898, Length=309, Percent_Identity=49.1909385113269, Blast_Score=277, Evalue=6e-75,
Organism=Drosophila melanogaster, GI24652801, Length=309, Percent_Identity=49.1909385113269, Blast_Score=277, Evalue=6e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 32907; Mature: 32776

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLLIIAEHLDGQLNAATAKTVSAALALSPEAIDIAVLAAIPDSVAAQAQHIAGVTRVL
CCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHEEEE
TIANPANKHPIAQILAPQIAALVQTNSYTHVFGPSTTFGKDLMPVVAALLNVNQISDLMG
EECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHC
LQDAYTFTRPIYAGNAIITVKAPTDQIVVATIRTASWPEAAKGGNATIETVTVSAHLPNH
CHHHHHHHCCEEECCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCC
TRFLSLDVHTCDRPDLQNAKRVVAGGRGLGSPENFKLIYTLADTLGAAVGASRAAVDAGY
EEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHHCCCHHHCCCCC
VPNELQIGQTGKIIAPDLYIAIGISGAIQHLTGIKDAGTIVAINQDADAPIFEIADIGLV
CCCCEEECCCCCEECCCEEEEEECCHHHHHHCCCCCCCEEEEECCCCCCCEEEHHHCCHH
GDLFQLIPELDMALNK
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKLLIIAEHLDGQLNAATAKTVSAALALSPEAIDIAVLAAIPDSVAAQAQHIAGVTRVL
CEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHEEEE
TIANPANKHPIAQILAPQIAALVQTNSYTHVFGPSTTFGKDLMPVVAALLNVNQISDLMG
EECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHC
LQDAYTFTRPIYAGNAIITVKAPTDQIVVATIRTASWPEAAKGGNATIETVTVSAHLPNH
CHHHHHHHCCEEECCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCC
TRFLSLDVHTCDRPDLQNAKRVVAGGRGLGSPENFKLIYTLADTLGAAVGASRAAVDAGY
EEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHHCCCHHHCCCCC
VPNELQIGQTGKIIAPDLYIAIGISGAIQHLTGIKDAGTIVAINQDADAPIFEIADIGLV
CCCCEEECCCCCEECCCEEEEEECCHHHHHHCCCCCCCEEEEECCCCCCCEEEHHHCCHH
GDLFQLIPELDMALNK
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]