Click here to switch to the map view.

The map label for this gene is accA

Identifier: 182680723

GI number: 182680723

Start: 207881

End: 208840

Strand: Reverse

Name: accA

Synonym: XfasM23_0152

Alternate gene names: 182680723

Gene position: 208840-207881 (Counterclockwise)

Preceding gene: 182680724

Following gene: 182680721

Centisome position: 8.24

GC content: 52.5

Gene sequence:

>960_bases
ATGAATCCAAACTATCTCGACTTCGAGCAACCCATCGCCGACCTGGAAGCCAAGATTCAGGACCTGCGCACCGCCAGTGC
AGGTCCATCTGTCAATGTCGACATCGAAGTACGTGCGCTTGAAAACAAACTGCGTCTTCGTACTGCACAGATCTTCCGTA
ATTTATCGGCTTGGCAAATCTCACAACTCGCTCGGCATCCACGGCGTCCTTACACCCTGGATTACATCTCCATTGTCTGC
GACGAATTCCAAGAACTAGCTGGGGATCGTACCTTAGCCGACGATAAAGCAATCGTTGGAGGTCTTGCCCGCATCGGCCA
CCGTCCAGTGATGCTTATCGGCCATCAAAAAGGACGTGACAATAAAGAACGCTTGATGCGCAACTTCGGCATGCCTAAAC
CCGAAGGCTACCGTAAAGCATTGCGCTTGATGAAGCTAGCTGAGCGTTTCGGTCTTCCCTTGTTGACTTTCATCGATACG
ATGGGTGCTTGGCCTGGTATCGACGCTGAAGAACGTAATCAATCCGAGGCCATTGCCACCAACCTGATTGAAATGGCCGA
GCTAAAAATTCCCGTCATCTGCACCGTCATCGGCGAAGGCGGTTCCGGTGGTGCTTTGGCGATCGGCATCGGTGACCGTA
CCCTGATGCTTGAGTACAGCACATACTCCGTCATCACCCCCGAGGGCTGCGCCTCAATCCTATGGAAAGATGCTGCCAAA
GCGAGCGATGCCGCTGAACAACTCAACCTCACTGCACGCCGACTGAAAGAATTCGGTCTAATAGACAAAGTGATCCGCGA
ACCCATTGGTGGCGCTCATCGTAATCCGCAACAGATGGCGAACCGCCTGAAAGCAGTGCTACTCAATGAACTCGAAGCAT
TGGATAAAGTTCCGCTGGTAACGCTTCTAAATCAGCGTCACAAGCGCCTGCGCACTTATGGGGCCTACGAGAACCATTGA

Upstream 100 bases:

>100_bases
CAATGAACAAGACCACAGCAGAGCACACACAGAAGCAATCCACAGCGGATTGCAACGTTATTCCGCTACACTTGCCACCC
TACGTCAAAGACGGTTTGCC

Downstream 100 bases:

>100_bases
GCCGCCCCGTACTGAGCGGCTCAAAGAGACTTAAATAGCATCGGGAAAAATAACATCCCAATCACCAGCAACCTGCTACG
GCGGCGCGAACGCTATGCGT

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MNPNYLDFEQPIADLEAKIQDLRTASAGPSVNVDIEVRALENKLRLRTAQIFRNLSAWQISQLARHPRRPYTLDYISIVC
DEFQELAGDRTLADDKAIVGGLARIGHRPVMLIGHQKGRDNKERLMRNFGMPKPEGYRKALRLMKLAERFGLPLLTFIDT
MGAWPGIDAEERNQSEAIATNLIEMAELKIPVICTVIGEGGSGGALAIGIGDRTLMLEYSTYSVITPEGCASILWKDAAK
ASDAAEQLNLTARRLKEFGLIDKVIREPIGGAHRNPQQMANRLKAVLLNELEALDKVPLVTLLNQRHKRLRTYGAYENH

Sequences:

>Translated_319_residues
MNPNYLDFEQPIADLEAKIQDLRTASAGPSVNVDIEVRALENKLRLRTAQIFRNLSAWQISQLARHPRRPYTLDYISIVC
DEFQELAGDRTLADDKAIVGGLARIGHRPVMLIGHQKGRDNKERLMRNFGMPKPEGYRKALRLMKLAERFGLPLLTFIDT
MGAWPGIDAEERNQSEAIATNLIEMAELKIPVICTVIGEGGSGGALAIGIGDRTLMLEYSTYSVITPEGCASILWKDAAK
ASDAAEQLNLTARRLKEFGLIDKVIREPIGGAHRNPQQMANRLKAVLLNELEALDKVPLVTLLNQRHKRLRTYGAYENH
>Mature_319_residues
MNPNYLDFEQPIADLEAKIQDLRTASAGPSVNVDIEVRALENKLRLRTAQIFRNLSAWQISQLARHPRRPYTLDYISIVC
DEFQELAGDRTLADDKAIVGGLARIGHRPVMLIGHQKGRDNKERLMRNFGMPKPEGYRKALRLMKLAERFGLPLLTFIDT
MGAWPGIDAEERNQSEAIATNLIEMAELKIPVICTVIGEGGSGGALAIGIGDRTLMLEYSTYSVITPEGCASILWKDAAK
ASDAAEQLNLTARRLKEFGLIDKVIREPIGGAHRNPQQMANRLKAVLLNELEALDKVPLVTLLNQRHKRLRTYGAYENH

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=317, Percent_Identity=64.0378548895899, Blast_Score=412, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_XYLF2 (B2I6R7)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001828883.1
- ProteinModelPortal:   B2I6R7
- SMR:   B2I6R7
- GeneID:   6203485
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0152
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35632; Mature: 35632

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPNYLDFEQPIADLEAKIQDLRTASAGPSVNVDIEVRALENKLRLRTAQIFRNLSAWQI
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCHHHHH
SQLARHPRRPYTLDYISIVCDEFQELAGDRTLADDKAIVGGLARIGHRPVMLIGHQKGRD
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCC
NKERLMRNFGMPKPEGYRKALRLMKLAERFGLPLLTFIDTMGAWPGIDAEERNQSEAIAT
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHCCHHHHHHH
NLIEMAELKIPVICTVIGEGGSGGALAIGIGDRTLMLEYSTYSVITPEGCASILWKDAAK
HHHHHHHCCCCEEEEEEECCCCCCEEEEEECCEEEEEEECCEEEECCHHHHHHHHHHHHH
ASDAAEQLNLTARRLKEFGLIDKVIREPIGGAHRNPQQMANRLKAVLLNELEALDKVPLV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
TLLNQRHKRLRTYGAYENH
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNPNYLDFEQPIADLEAKIQDLRTASAGPSVNVDIEVRALENKLRLRTAQIFRNLSAWQI
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCHHHHH
SQLARHPRRPYTLDYISIVCDEFQELAGDRTLADDKAIVGGLARIGHRPVMLIGHQKGRD
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCC
NKERLMRNFGMPKPEGYRKALRLMKLAERFGLPLLTFIDTMGAWPGIDAEERNQSEAIAT
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHCCHHHHHHH
NLIEMAELKIPVICTVIGEGGSGGALAIGIGDRTLMLEYSTYSVITPEGCASILWKDAAK
HHHHHHHCCCCEEEEEEECCCCCCEEEEEECCEEEEEEECCEEEECCHHHHHHHHHHHHH
ASDAAEQLNLTARRLKEFGLIDKVIREPIGGAHRNPQQMANRLKAVLLNELEALDKVPLV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
TLLNQRHKRLRTYGAYENH
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA