BacMap

Definition	Xylella fastidiosa M23 chromosome, complete genome.
Accession	NC_010577
Length	2,535,690

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The map label for this gene is fabG

Identifier: 182680700

GI number: 182680700

Start: 180844

End: 181584

Strand: Reverse

Name: fabG

Synonym: XfasM23_0129

Alternate gene names: 182680700

Gene position: 181584-180844 (Counterclockwise)

Preceding gene: 182680703

Following gene: 182680698

Centisome position: 7.16

GC content: 50.88

Gene sequence:

>741_bases
ATGATTACTGATGACTCTCCAAGATTCCGTGCACTAGTGACTGGCGGAAGTGGTAATTTGGGTACTGCCATTTGCCGTCA
ATTAATTGCAGATGGTGCGCATGTCATCGTCCATGCAAACCACCATCGGTCTCGTGCTGATACCCTAGTGGAATGCTTAT
GTGCCGAAGGGGGGAGCGCTGAGGTAATTGTTTTCGACGTCACCGCCGCACAAGCCAGCAAAACGGCACTGGAAAACTTG
TTACAGGCTGGCCCAATCCAGATCATAATTAATAATGCAGGCATCCACGACGACGCACCGATGGCTGGCATGTCATCTAC
ACAATGGCATCGTGTCATTGATGTCTCTCTGCACGGCTTTTTCAACGTAACTCAACCGTTGCTGCTGCCGATGGCACGCA
CCCGTTGGGGACGTATTGTATGCATATCATCTGTTACGGCAGTTTTAGGAAACCGCGGACAGAGTAACTACGCAGCAGCC
AAAGCAGGGTTACACGGTGCGGCACGCTCATTGGCCCGTGAGATGGCTAATCGTGGCATCACCGTTAACGTCGTAGCACC
AGGTGTGATTGAAAGTGAGATGGTAGGGAAAACGTTTACTCCGGAAATGATCAAGCAATTGGTACCAACCGGTCGTCCCG
GTCGTCCCGAGGAAGTGGCTGCTCTGATCGGATTCCTATGCTCAGAGAAAGCAGGTTATATCAACGGTCAAGTCATCGGC
ATCAATGGTGGAATGGTTTAA

Upstream 100 bases:

>100_bases
GCTAATCGTAGATCGTCTACTTGCCTCCATGCAGTTCAGTTTACGATGGTTAACATTTGCTTCAATCACAGTCTACCCAC
TGATCTTGGAACATGTATCT

Downstream 100 bases:

>100_bases
TCATATCTTATCCAAAATAATTTCATCACATACTCACTTTTCCAATGATTAGTATCGTGACTCACCTTGATTTAAATAAC
CTTCTCATAAAAATATCAGG

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MITDDSPRFRALVTGGSGNLGTAICRQLIADGAHVIVHANHHRSRADTLVECLCAEGGSAEVIVFDVTAAQASKTALENL
LQAGPIQIIINNAGIHDDAPMAGMSSTQWHRVIDVSLHGFFNVTQPLLLPMARTRWGRIVCISSVTAVLGNRGQSNYAAA
KAGLHGAARSLAREMANRGITVNVVAPGVIESEMVGKTFTPEMIKQLVPTGRPGRPEEVAALIGFLCSEKAGYINGQVIG
INGGMV

Sequences:

>Translated_246_residues
MITDDSPRFRALVTGGSGNLGTAICRQLIADGAHVIVHANHHRSRADTLVECLCAEGGSAEVIVFDVTAAQASKTALENL
LQAGPIQIIINNAGIHDDAPMAGMSSTQWHRVIDVSLHGFFNVTQPLLLPMARTRWGRIVCISSVTAVLGNRGQSNYAAA
KAGLHGAARSLAREMANRGITVNVVAPGVIESEMVGKTFTPEMIKQLVPTGRPGRPEEVAALIGFLCSEKAGYINGQVIG
INGGMV
>Mature_246_residues
MITDDSPRFRALVTGGSGNLGTAICRQLIADGAHVIVHANHHRSRADTLVECLCAEGGSAEVIVFDVTAAQASKTALENL
LQAGPIQIIINNAGIHDDAPMAGMSSTQWHRVIDVSLHGFFNVTQPLLLPMARTRWGRIVCISSVTAVLGNRGQSNYAAA
KAGLHGAARSLAREMANRGITVNVVAPGVIESEMVGKTFTPEMIKQLVPTGRPGRPEEVAALIGFLCSEKAGYINGQVIG
INGGMV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=35.2226720647773, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=32.0987654320988, Blast_Score=110, Evalue=9e-25,
Organism=Homo sapiens, GI4504505, Length=228, Percent_Identity=34.6491228070175, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI19923817, Length=249, Percent_Identity=31.3253012048193, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI40254992, Length=237, Percent_Identity=30.8016877637131, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=30.3643724696356, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI4503301, Length=221, Percent_Identity=30.316742081448, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI126723750, Length=244, Percent_Identity=27.4590163934426, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI10190704, Length=244, Percent_Identity=31.1475409836066, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=28.4584980237154, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=27.8008298755187, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=30.4123711340206, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI7657478, Length=199, Percent_Identity=29.1457286432161, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=28.448275862069, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI20149619, Length=189, Percent_Identity=26.4550264550265, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=41.0041841004184, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1790717, Length=241, Percent_Identity=30.7053941908714, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=32.5301204819277, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=29.8755186721992, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=32.2448979591837, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI2367365, Length=238, Percent_Identity=30.2521008403361, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=28.4584980237154, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=26.1410788381743, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1786812, Length=194, Percent_Identity=31.4432989690722, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=28.90625, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=28.1632653061224, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789208, Length=170, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17555706, Length=242, Percent_Identity=34.297520661157, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=32.9166666666667, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=30.8943089430894, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=36.4102564102564, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17536651, Length=245, Percent_Identity=30.6122448979592, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17536025, Length=246, Percent_Identity=30.0813008130081, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=29.1338582677165, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17563726, Length=253, Percent_Identity=29.2490118577075, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=256, Percent_Identity=30.46875, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=254, Percent_Identity=29.5275590551181, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=29.1828793774319, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=233, Percent_Identity=31.3304721030043, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=252, Percent_Identity=28.968253968254, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=28.030303030303, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=254, Percent_Identity=27.9527559055118, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=256, Percent_Identity=30.078125, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=30.2040816326531, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=27.1255060728745, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=27.906976744186, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=28.90625, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=259, Percent_Identity=30.1158301158301, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=257, Percent_Identity=30.7392996108949, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=26.8292682926829, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=255, Percent_Identity=28.2352941176471, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=256, Percent_Identity=27.34375, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=251, Percent_Identity=28.2868525896414, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=29.4339622641509, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=259, Percent_Identity=27.4131274131274, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=232, Percent_Identity=31.4655172413793, Blast_Score=109, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6324126, Length=244, Percent_Identity=26.6393442622951, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323882, Length=227, Percent_Identity=28.1938325991189, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=36.8852459016393, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI18859837, Length=228, Percent_Identity=32.0175438596491, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24644339, Length=242, Percent_Identity=28.9256198347107, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=27.4590163934426, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24643142, Length=238, Percent_Identity=30.2521008403361, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI23397609, Length=242, Percent_Identity=29.3388429752066, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571526, Length=242, Percent_Identity=27.6859504132231, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=27.8884462151394, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=28.0632411067194, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR011285
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25869; Mature: 25869

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITDDSPRFRALVTGGSGNLGTAICRQLIADGAHVIVHANHHRSRADTLVECLCAEGGSA
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCCC
EVIVFDVTAAQASKTALENLLQAGPIQIIINNAGIHDDAPMAGMSSTQWHRVIDVSLHGF
EEEEEEECHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCC
FNVTQPLLLPMARTRWGRIVCISSVTAVLGNRGQSNYAAAKAGLHGAARSLAREMANRGI
CCCHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCE
TVNVVAPGVIESEMVGKTFTPEMIKQLVPTGRPGRPEEVAALIGFLCSEKAGYINGQVIG
EEEEECCCCHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEE
INGGMV
ECCCCC
>Mature Secondary Structure
MITDDSPRFRALVTGGSGNLGTAICRQLIADGAHVIVHANHHRSRADTLVECLCAEGGSA
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCCC
EVIVFDVTAAQASKTALENLLQAGPIQIIINNAGIHDDAPMAGMSSTQWHRVIDVSLHGF
EEEEEEECHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCC
FNVTQPLLLPMARTRWGRIVCISSVTAVLGNRGQSNYAAAKAGLHGAARSLAREMANRGI
CCCHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCE
TVNVVAPGVIESEMVGKTFTPEMIKQLVPTGRPGRPEEVAALIGFLCSEKAGYINGQVIG
EEEEECCCCHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEE
INGGMV
ECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]