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The map label for this gene is prlC [H]

Identifier: 182680660

GI number: 182680660

Start: 123323

End: 125347

Strand: Reverse

Name: prlC [H]

Synonym: XfasM23_0089

Alternate gene names: 182680660

Gene position: 125347-123323 (Counterclockwise)

Preceding gene: 182680661

Following gene: 182680654

Centisome position: 4.94

GC content: 56.4

Gene sequence:

>2025_bases
ATGAGTAACCCACTCCTCGATTTCTCAGACCTTCCTCGCTTCGACGCGATCCTCCCTGAACACGTTGGCCCGGCCATTGA
GCAGTTGCTCGCAGAGGCGGAGGCAGCCGTCGCCCACGCGGAACAGGTAACGCCGGTGACATGGGAGAACTTCGTAGTAC
CGCTGGACGATGCCACCGAGCGGTTGTATCGCGCGTGGGGCCAGGTGGCGCATTTGGAGGCGGTGGTCAACACGCCGGCG
CTGCGTGAGGCGTATAACGTCACTCTGCCGAAAGTCACTCGATTCAGCAGTACGCTCGGACAGAACCTGGCGCTGTATGC
GCAGTACAAAGCATTAGCGTGTGCGCCGGAATGGGACCGTGATAATGCGGTACGGTGCAAGGTTGTTGATAACGCTTTGC
GTGATTTCCGTCTCGGCGGTGCCGAGCTGGATGCCGCCGGGAAAGCTCGTCTGGCAGAGATCAAGCAGGAGCTGTCGGCA
TTGTCTGCAACGTTTTCGCAAAATGTGCTTGATGCAACAGAGGCATGGTCCTACACCACCGAAGACGCCGCTTTGTTATC
CGGTCTGCCGACAGAGACTGTCGCTACCGCGCGGGCGGCCGCAGAAAAGAAGGGGGTATCAGGCTGGACGTTCACGTTAC
AGATGCCCTGCTATCTGTCGGTCCAAAGCGATGCTGACAACCGCGCGTTACGAGAGCGCTCATATCATGCTAGTGCGATA
CGCGCTTCGGAATTTGGCGATGCCGCTTTGGATAATAGTCCGCACATTCATCAGATTCTCACGCTGCGTTCCGAATTGGC
AGCGCTGCTTGGTTTCTCCTGTTACGCGGCATACTCGGTCGCAACCAAGATGGCAGAGGATCCAGCTGAGGTACTCAGCT
TCCTGCATGACTTGGCAGGACGTGCCAAGCCGCATGCTCAACGTGATCGCCGTGAACTGGAAACGTTCGCACGCGAGGCG
CTGGGGCTTGAGACGCTGGAAGCCTGGGACATTGCATATGCCAGTGAGAAGCTGAAACAAGCCCGTTACAATTTCTCCGA
GCAGGAAGTAAAGCAGTATTTCACCGAACCCAAGGTCCTGGCTGGGTTGTTCGAGGTGATCCGCTCCCTGTATGGACTGC
GAATCGAAGAAGACGCCGCGCCGGTCTGGCATCCAGATGTTCGCTTCTACCGTCTCATTGATACGAATGGGCAACGCGTC
GGCCAGTTTTATCTGGATCTGTATGCACGGGAGGGCAAGCGCGGCGGGGCATGGATGGATGATTGCCGTAACCGCCGTGA
CAAAGGCGATGGGGTGCAAACTCCGGTGGTCTATTTGGTGTGCAATTTCGGTCGTGGTAACGACGGTGTGCTGCCTACGT
TCCGTCATCAGGAGGTCATTACTTTATTTCACGAAATGGGCCATGGGCTGCATCAGTTACTGACCCGGATTGGGGAACTG
GGCGTGGCTGGTATTAATGGTGTGGAATGGGATGCGGTGGAGTTGCCCAGTCAGTTCATGGAAAACTTTTGCTGGGAGTG
GGAACGCGTTCAAGCCATGACGGCACACGTGGAGACCGGTGCACCGCTGCCACGCAGTCTGTTCGATCGGATGGTCTGCG
CGCGCAATTTTCAGAGCGGAATGTTCACCGTGCGCCAACTTGAGTTCGCGCTATTCGACATGCTGCTACATAGTGACTTC
GATCCAGCACAGGACAGCGTACTGGGACTGTTAGAACGCGTCCGTGATGAAGTGGCCGTCAACCGGTTACCGGACTGGAA
TCGTTTTCCGCACCAGTTCAGACATATTTTTGCTGGTGGTTATGCAGCGGGATATTACAGTTACAAATGGGCCGAAGTCC
TCAGCGCAGACGCTTATGCTGCATTTGAAGAGGCTCCGGATCAATTTGCCGAAATAGGGGCGCGCTTTCTCGACGAAATC
CTAAGTCGTGGCGGCAGTCGCAGCGCAGCAGAGAATTTCCAAGCCTTCCGCAAACGCGCGCCTCGCATTGATGCCTTGCT
GAAGCGCAACGGGATGACAGAATAG

Upstream 100 bases:

>100_bases
GTGATACGTTGCCGCTGCTTCCTTGCGCGGCTCTGGAATGACACCATAATCGGTAGGCATCTCCGCATTTGGCTGCATTC
CCAAGACACAGAAGACACAC

Downstream 100 bases:

>100_bases
GTGTTGAACAACCACGCACCGTTTTTTCAGAGCCGCAGCCCTATGTGCTGCGGCATAACGCGTTAAAAGCATTAATACTT
CGTTTTCATGTATACACCGG

Product: oligopeptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 674; Mature: 673

Protein sequence:

>674_residues
MSNPLLDFSDLPRFDAILPEHVGPAIEQLLAEAEAAVAHAEQVTPVTWENFVVPLDDATERLYRAWGQVAHLEAVVNTPA
LREAYNVTLPKVTRFSSTLGQNLALYAQYKALACAPEWDRDNAVRCKVVDNALRDFRLGGAELDAAGKARLAEIKQELSA
LSATFSQNVLDATEAWSYTTEDAALLSGLPTETVATARAAAEKKGVSGWTFTLQMPCYLSVQSDADNRALRERSYHASAI
RASEFGDAALDNSPHIHQILTLRSELAALLGFSCYAAYSVATKMAEDPAEVLSFLHDLAGRAKPHAQRDRRELETFAREA
LGLETLEAWDIAYASEKLKQARYNFSEQEVKQYFTEPKVLAGLFEVIRSLYGLRIEEDAAPVWHPDVRFYRLIDTNGQRV
GQFYLDLYAREGKRGGAWMDDCRNRRDKGDGVQTPVVYLVCNFGRGNDGVLPTFRHQEVITLFHEMGHGLHQLLTRIGEL
GVAGINGVEWDAVELPSQFMENFCWEWERVQAMTAHVETGAPLPRSLFDRMVCARNFQSGMFTVRQLEFALFDMLLHSDF
DPAQDSVLGLLERVRDEVAVNRLPDWNRFPHQFRHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAPDQFAEIGARFLDEI
LSRGGSRSAAENFQAFRKRAPRIDALLKRNGMTE

Sequences:

>Translated_674_residues
MSNPLLDFSDLPRFDAILPEHVGPAIEQLLAEAEAAVAHAEQVTPVTWENFVVPLDDATERLYRAWGQVAHLEAVVNTPA
LREAYNVTLPKVTRFSSTLGQNLALYAQYKALACAPEWDRDNAVRCKVVDNALRDFRLGGAELDAAGKARLAEIKQELSA
LSATFSQNVLDATEAWSYTTEDAALLSGLPTETVATARAAAEKKGVSGWTFTLQMPCYLSVQSDADNRALRERSYHASAI
RASEFGDAALDNSPHIHQILTLRSELAALLGFSCYAAYSVATKMAEDPAEVLSFLHDLAGRAKPHAQRDRRELETFAREA
LGLETLEAWDIAYASEKLKQARYNFSEQEVKQYFTEPKVLAGLFEVIRSLYGLRIEEDAAPVWHPDVRFYRLIDTNGQRV
GQFYLDLYAREGKRGGAWMDDCRNRRDKGDGVQTPVVYLVCNFGRGNDGVLPTFRHQEVITLFHEMGHGLHQLLTRIGEL
GVAGINGVEWDAVELPSQFMENFCWEWERVQAMTAHVETGAPLPRSLFDRMVCARNFQSGMFTVRQLEFALFDMLLHSDF
DPAQDSVLGLLERVRDEVAVNRLPDWNRFPHQFRHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAPDQFAEIGARFLDEI
LSRGGSRSAAENFQAFRKRAPRIDALLKRNGMTE
>Mature_673_residues
SNPLLDFSDLPRFDAILPEHVGPAIEQLLAEAEAAVAHAEQVTPVTWENFVVPLDDATERLYRAWGQVAHLEAVVNTPAL
REAYNVTLPKVTRFSSTLGQNLALYAQYKALACAPEWDRDNAVRCKVVDNALRDFRLGGAELDAAGKARLAEIKQELSAL
SATFSQNVLDATEAWSYTTEDAALLSGLPTETVATARAAAEKKGVSGWTFTLQMPCYLSVQSDADNRALRERSYHASAIR
ASEFGDAALDNSPHIHQILTLRSELAALLGFSCYAAYSVATKMAEDPAEVLSFLHDLAGRAKPHAQRDRRELETFAREAL
GLETLEAWDIAYASEKLKQARYNFSEQEVKQYFTEPKVLAGLFEVIRSLYGLRIEEDAAPVWHPDVRFYRLIDTNGQRVG
QFYLDLYAREGKRGGAWMDDCRNRRDKGDGVQTPVVYLVCNFGRGNDGVLPTFRHQEVITLFHEMGHGLHQLLTRIGELG
VAGINGVEWDAVELPSQFMENFCWEWERVQAMTAHVETGAPLPRSLFDRMVCARNFQSGMFTVRQLEFALFDMLLHSDFD
PAQDSVLGLLERVRDEVAVNRLPDWNRFPHQFRHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAPDQFAEIGARFLDEIL
SRGGSRSAAENFQAFRKRAPRIDALLKRNGMTE

Specific function: May play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. Can cleave N-acetyl-L-Ala(4) [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=549, Percent_Identity=32.4225865209472, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI14149738, Length=666, Percent_Identity=26.7267267267267, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI156105687, Length=661, Percent_Identity=23.7518910741301, Blast_Score=143, Evalue=5e-34,
Organism=Escherichia coli, GI1789913, Length=678, Percent_Identity=50.1474926253687, Blast_Score=645, Evalue=0.0,
Organism=Escherichia coli, GI1787819, Length=688, Percent_Identity=29.9418604651163, Blast_Score=250, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71999758, Length=516, Percent_Identity=23.6434108527132, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32565901, Length=589, Percent_Identity=21.9015280135823, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6319793, Length=689, Percent_Identity=27.4310595065312, Blast_Score=262, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6322715, Length=645, Percent_Identity=24.6511627906977, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21356111, Length=551, Percent_Identity=30.8529945553539, Blast_Score=230, Evalue=3e-60,
Organism=Drosophila melanogaster, GI20129717, Length=402, Percent_Identity=25.8706467661692, Blast_Score=122, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.24.70 [H]

Molecular weight: Translated: 75568; Mature: 75437

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPLLDFSDLPRFDAILPEHVGPAIEQLLAEAEAAVAHAEQVTPVTWENFVVPLDDATE
CCCCCCCHHCCCHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHH
RLYRAWGQVAHLEAVVNTPALREAYNVTLPKVTRFSSTLGQNLALYAQYKALACAPEWDR
HHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHCCCCEEEEHHHHHEECCCCCC
DNAVRCKVVDNALRDFRLGGAELDAAGKARLAEIKQELSALSATFSQNVLDATEAWSYTT
CCCEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EDAALLSGLPTETVATARAAAEKKGVSGWTFTLQMPCYLSVQSDADNRALRERSYHASAI
CHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCHHHHHHHHHHHHHH
RASEFGDAALDNSPHIHQILTLRSELAALLGFSCYAAYSVATKMAEDPAEVLSFLHDLAG
HHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
RAKPHAQRDRRELETFAREALGLETLEAWDIAYASEKLKQARYNFSEQEVKQYFTEPKVL
CCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHH
AGLFEVIRSLYGLRIEEDAAPVWHPDVRFYRLIDTNGQRVGQFYLDLYAREGKRGGAWMD
HHHHHHHHHHHCCEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHH
DCRNRRDKGDGVQTPVVYLVCNFGRGNDGVLPTFRHQEVITLFHEMGHGLHQLLTRIGEL
HHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHC
GVAGINGVEWDAVELPSQFMENFCWEWERVQAMTAHVETGAPLPRSLFDRMVCARNFQSG
CCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
MFTVRQLEFALFDMLLHSDFDPAQDSVLGLLERVRDEVAVNRLPDWNRFPHQFRHIFAGG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
YAAGYYSYKWAEVLSADAYAAFEEAPDQFAEIGARFLDEILSRGGSRSAAENFQAFRKRA
HHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
PRIDALLKRNGMTE
CHHHHHHHHCCCCC
>Mature Secondary Structure 
SNPLLDFSDLPRFDAILPEHVGPAIEQLLAEAEAAVAHAEQVTPVTWENFVVPLDDATE
CCCCCCHHCCCHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHH
RLYRAWGQVAHLEAVVNTPALREAYNVTLPKVTRFSSTLGQNLALYAQYKALACAPEWDR
HHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHCCCCEEEEHHHHHEECCCCCC
DNAVRCKVVDNALRDFRLGGAELDAAGKARLAEIKQELSALSATFSQNVLDATEAWSYTT
CCCEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EDAALLSGLPTETVATARAAAEKKGVSGWTFTLQMPCYLSVQSDADNRALRERSYHASAI
CHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCHHHHHHHHHHHHHH
RASEFGDAALDNSPHIHQILTLRSELAALLGFSCYAAYSVATKMAEDPAEVLSFLHDLAG
HHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
RAKPHAQRDRRELETFAREALGLETLEAWDIAYASEKLKQARYNFSEQEVKQYFTEPKVL
CCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHH
AGLFEVIRSLYGLRIEEDAAPVWHPDVRFYRLIDTNGQRVGQFYLDLYAREGKRGGAWMD
HHHHHHHHHHHCCEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHH
DCRNRRDKGDGVQTPVVYLVCNFGRGNDGVLPTFRHQEVITLFHEMGHGLHQLLTRIGEL
HHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHC
GVAGINGVEWDAVELPSQFMENFCWEWERVQAMTAHVETGAPLPRSLFDRMVCARNFQSG
CCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
MFTVRQLEFALFDMLLHSDFDPAQDSVLGLLERVRDEVAVNRLPDWNRFPHQFRHIFAGG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
YAAGYYSYKWAEVLSADAYAAFEEAPDQFAEIGARFLDEILSRGGSRSAAENFQAFRKRA
HHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
PRIDALLKRNGMTE
CHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]