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The map label for this gene is cynT [H]

Identifier: 182677605

GI number: 182677605

Start: 691422

End: 692105

Strand: Direct

Name: cynT [H]

Synonym: Bind_0612

Alternate gene names: 182677605

Gene position: 691422-692105 (Clockwise)

Preceding gene: 182677604

Following gene: 182677612

Centisome position: 16.58

GC content: 53.36

Gene sequence:

>684_bases
ATGCATTCATGTTCTGATGCCAAAACCAGTCTGCTCGCGCTTCTTAATGGTGTCAAGCGTTTCAATACGGAAGTTTTCCC
AGCCAAGGAAGAGCTCTTCGCTCATCTGTCGAAGAGTCAGTCTCCCCACGTGGTGTTCATCACCTGCGCTGACAGCCAAA
TTACTCCCAGTCTCATCACGCAAACGGAACCCGGCGAGCTATTTATTCTTCGCAACATTGGCAATCTGGTGCCGCCTTAT
GGGGAAATGCTTGGGGGTGTTTCATCCGTTATCGAATATGCTGTGGTGGGGCTTAACGTCTCGGCTATCATCATCTGTGG
CCATTCCGATTGCGGCGCCATGAAAGCCTTGCTTCTGCCCGAGAAAGGCCATCTGGACCAGATGCCTACCGTACGGACTT
GGCTTCGGAATGCTGCAGCGGCACGCGCCGCCTTGGGGGATATCCGCGACGAGGATGTCGGCCCGGAAAAAGTCCGCAAC
TTGGCGGAGCAAAATGTGCTTCTCCAGATCGCGCAACTGAAAACACATCCATCTGTGGCCGCGGCACTGGCGCGCGGGAC
TTTATTCCTGCAAGGCTGGTTTTATGACATTGGCACAGGCGAGATCAGTGTCCTTGATGAACAAACACGGAAAAGCCTGT
CCGTCAAGGAAGCGATCAAGAACCTGGAAAGTGAGCAATCCTAA

Upstream 100 bases:

>100_bases
TTTATCGTACGTTATTTCAGTACGTTGAGTTGAGCGATCGCGCGCCTTTGAGGAAGCAGGTGCTTTTGCCGCATTGTCCC
GTCATATTCGGAGAGGCCTG

Downstream 100 bases:

>100_bases
AGCTTCTATTCTTTACGGAGAATGGTGACGATATCGTCGTCTTATAGGCTCTCCGCTCACCTTCTTTCGGGTCGTTTTTA
TCAAACGACGCTTCTCGCGC

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 1 [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MHSCSDAKTSLLALLNGVKRFNTEVFPAKEELFAHLSKSQSPHVVFITCADSQITPSLITQTEPGELFILRNIGNLVPPY
GEMLGGVSSVIEYAVVGLNVSAIIICGHSDCGAMKALLLPEKGHLDQMPTVRTWLRNAAAARAALGDIRDEDVGPEKVRN
LAEQNVLLQIAQLKTHPSVAAALARGTLFLQGWFYDIGTGEISVLDEQTRKSLSVKEAIKNLESEQS

Sequences:

>Translated_227_residues
MHSCSDAKTSLLALLNGVKRFNTEVFPAKEELFAHLSKSQSPHVVFITCADSQITPSLITQTEPGELFILRNIGNLVPPY
GEMLGGVSSVIEYAVVGLNVSAIIICGHSDCGAMKALLLPEKGHLDQMPTVRTWLRNAAAARAALGDIRDEDVGPEKVRN
LAEQNVLLQIAQLKTHPSVAAALARGTLFLQGWFYDIGTGEISVLDEQTRKSLSVKEAIKNLESEQS
>Mature_227_residues
MHSCSDAKTSLLALLNGVKRFNTEVFPAKEELFAHLSKSQSPHVVFITCADSQITPSLITQTEPGELFILRNIGNLVPPY
GEMLGGVSSVIEYAVVGLNVSAIIICGHSDCGAMKALLLPEKGHLDQMPTVRTWLRNAAAARAALGDIRDEDVGPEKVRN
LAEQNVLLQIAQLKTHPSVAAALARGTLFLQGWFYDIGTGEISVLDEQTRKSLSVKEAIKNLESEQS

Specific function: Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to c

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=198, Percent_Identity=46.969696969697, Blast_Score=196, Evalue=8e-52,
Organism=Escherichia coli, GI1786318, Length=200, Percent_Identity=32, Blast_Score=87, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI115532990, Length=256, Percent_Identity=27.34375, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25147564, Length=237, Percent_Identity=24.8945147679325, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324292, Length=187, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24645213, Length=246, Percent_Identity=25.609756097561, Blast_Score=84, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24562; Mature: 24562

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSCSDAKTSLLALLNGVKRFNTEVFPAKEELFAHLSKSQSPHVVFITCADSQITPSLIT
CCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHC
QTEPGELFILRNIGNLVPPYGEMLGGVSSVIEYAVVGLNVSAIIICGHSDCGAMKALLLP
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCC
EKGHLDQMPTVRTWLRNAAAARAALGDIRDEDVGPEKVRNLAEQNVLLQIAQLKTHPSVA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
AALARGTLFLQGWFYDIGTGEISVLDEQTRKSLSVKEAIKNLESEQS
HHHHHCEEEEEEEEEEECCCEEEEECHHHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure
MHSCSDAKTSLLALLNGVKRFNTEVFPAKEELFAHLSKSQSPHVVFITCADSQITPSLIT
CCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHC
QTEPGELFILRNIGNLVPPYGEMLGGVSSVIEYAVVGLNVSAIIICGHSDCGAMKALLLP
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCC
EKGHLDQMPTVRTWLRNAAAARAALGDIRDEDVGPEKVRNLAEQNVLLQIAQLKTHPSVA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
AALARGTLFLQGWFYDIGTGEISVLDEQTRKSLSVKEAIKNLESEQS
HHHHHCEEEEEEEEEEECCCEEEEECHHHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]