BacMap

Definition	Beijerinckia indica subsp. indica ATCC 9039 chromosome, complete genome.
Accession	NC_010581
Length	4,170,153

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The map label for this gene is kduD [C]

Identifier: 182677575

GI number: 182677575

Start: 643870

End: 644637

Strand: Direct

Name: kduD [C]

Synonym: Bind_0580

Alternate gene names: 182677575

Gene position: 643870-644637 (Clockwise)

Preceding gene: 182677573

Following gene: 182677576

Centisome position: 15.44

GC content: 64.06

Gene sequence:

>768_bases
ATGACGACGAATGAGACGAAGATCGCCTTGGTGACTGGCGCGAGCCGGGGCCTGGGACGCAGCATGGCCATCGCGCTCGC
TCATAAAGGTGTGGACGTGATTGGGACCTATCACAGCAACAAGGCGGAAGCCGACGCCACCGTGGCCGCCGTCGAGGCGC
TCGGCCGCAAGGCGGTGATGTTCCAGCTCGATACCAGCAACACGGCCAGCTTCGCTTCCTTTGCGGTGGATCTGAAGCAA
AGGCTCGCGGCCAATTGGAACCGCTCGACCTTCGACTACCTAGTCAACAATGCTGGAATCGGCATCTACGCCCCCTTCGC
CGAGACGAGCGAGGCCGATTTTGACCGGTTGATGAACATCCACCTCAAGGGCGTGTTCTTCTTGACCCAGGCCCTGCTGC
CCCTGATCGCCGATGGCGGCCGTATCGTGAACCTGTCGAGCGGCCTCACCCGCTTCAGCCTGCCGGGTTATGCCGCCTAT
GCGGCGATGAAGGGCGCGGTGGAAGTGCTGACCCGCTATCTCGCGAAGGAACTGGGGCCGCGCGGCATCGGCGTCAACAC
CATCGCCCCCGGTGCGATCGAGACCGATTTCGGCGGCGGATCGGTGCGCGACAACAAGCAGGTGAACGACTTCATCGCCA
GCGTGACGGCGCTCGGGCGCCCCGGTCTGCCCGACGACATTGGCCCCGCCGTCGCGTCGCTGCTGACCGAGGACAATCGC
TGGATCAACGCCCAGCGGATCGAAGTCTCCGGCGGCATGTTCGTGTGA

Upstream 100 bases:

>100_bases
CCCGAATAGTGATCGCGAATAATCGCCGATTATCTGGCTGATGAAAATGGTCATCTAAGGGCATGTCCGGAGCGATCGAG
CCCGGAAAGGGAGAGGCAAG

Downstream 100 bases:

>100_bases
TCGAGAGGGGGACCGACATGGGACAGGTTATCGTCATCACCGGCGCTTCCAGCGGCTTCGGAGCGCTGACGGCTCGAGCC
CTCGCCGATGCCGGGCATAT

Product: short-chain dehydrogenase/reductase SDR

Products: @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate!; NADH. [C]

Alternate protein names: ORFC [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MTTNETKIALVTGASRGLGRSMAIALAHKGVDVIGTYHSNKAEADATVAAVEALGRKAVMFQLDTSNTASFASFAVDLKQ
RLAANWNRSTFDYLVNNAGIGIYAPFAETSEADFDRLMNIHLKGVFFLTQALLPLIADGGRIVNLSSGLTRFSLPGYAAY
AAMKGAVEVLTRYLAKELGPRGIGVNTIAPGAIETDFGGGSVRDNKQVNDFIASVTALGRPGLPDDIGPAVASLLTEDNR
WINAQRIEVSGGMFV

Sequences:

>Translated_255_residues
MTTNETKIALVTGASRGLGRSMAIALAHKGVDVIGTYHSNKAEADATVAAVEALGRKAVMFQLDTSNTASFASFAVDLKQ
RLAANWNRSTFDYLVNNAGIGIYAPFAETSEADFDRLMNIHLKGVFFLTQALLPLIADGGRIVNLSSGLTRFSLPGYAAY
AAMKGAVEVLTRYLAKELGPRGIGVNTIAPGAIETDFGGGSVRDNKQVNDFIASVTALGRPGLPDDIGPAVASLLTEDNR
WINAQRIEVSGGMFV
>Mature_254_residues
TTNETKIALVTGASRGLGRSMAIALAHKGVDVIGTYHSNKAEADATVAAVEALGRKAVMFQLDTSNTASFASFAVDLKQR
LAANWNRSTFDYLVNNAGIGIYAPFAETSEADFDRLMNIHLKGVFFLTQALLPLIADGGRIVNLSSGLTRFSLPGYAAYA
AMKGAVEVLTRYLAKELGPRGIGVNTIAPGAIETDFGGGSVRDNKQVNDFIASVTALGRPGLPDDIGPAVASLLTEDNRW
INAQRIEVSGGMFV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=33.4615384615385, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=30.2788844621514, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=28.6290322580645, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=27.6679841897233, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=27.4193548387097, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40254992, Length=251, Percent_Identity=28.2868525896414, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI150247226, Length=193, Percent_Identity=32.1243523316062, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4504505, Length=258, Percent_Identity=28.6821705426357, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7657478, Length=198, Percent_Identity=29.7979797979798, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=28.8659793814433, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=34.3873517786561, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=34.251968503937, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=32.1428571428571, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI2367175, Length=258, Percent_Identity=32.5581395348837, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=31.4516129032258, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=29.2490118577075, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=29.6747967479675, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=31.640625, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=31.0483870967742, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=28.1746031746032, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787526, Length=192, Percent_Identity=35.4166666666667, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786701, Length=193, Percent_Identity=33.6787564766839, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787820, Length=229, Percent_Identity=27.0742358078603, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=29.0836653386454, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=29.2490118577075, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=28.6852589641434, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=32.5581395348837, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=30.8270676691729, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=196, Percent_Identity=34.1836734693878, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=272, Percent_Identity=30.1470588235294, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=27.3092369477912, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=273, Percent_Identity=31.5018315018315, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=28.6852589641434, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=30.3370786516854, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=28.5171102661597, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=201, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=26.7716535433071, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=206, Percent_Identity=33.495145631068, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17557780, Length=198, Percent_Identity=30.3030303030303, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=208, Percent_Identity=33.6538461538462, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=28.030303030303, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17555612, Length=266, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=28.957528957529, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=262, Percent_Identity=27.4809160305344, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=27.7153558052434, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=28.3524904214559, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=24.6031746031746, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=277, Percent_Identity=28.158844765343, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=32.3076923076923, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=208, Percent_Identity=30.2884615384615, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=34.5381526104418, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=33.4615384615385, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=34.3873517786561, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21357041, Length=259, Percent_Identity=32.8185328185328, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=30.2681992337165, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=29.6442687747036, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=28.8, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21358495, Length=199, Percent_Identity=31.6582914572864, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644337, Length=166, Percent_Identity=34.3373493975904, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24651139, Length=203, Percent_Identity=29.5566502463054, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI18859837, Length=196, Percent_Identity=31.6326530612245, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24649181, Length=196, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.125 [C]

Molecular weight: Translated: 26956; Mature: 26825

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNETKIALVTGASRGLGRSMAIALAHKGVDVIGTYHSNKAEADATVAAVEALGRKAVM
CCCCCEEEEEEECCCCCCCHHHEEHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEE
FQLDTSNTASFASFAVDLKQRLAANWNRSTFDYLVNNAGIGIYAPFAETSEADFDRLMNI
EEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHH
HLKGVFFLTQALLPLIADGGRIVNLSSGLTRFSLPGYAAYAAMKGAVEVLTRYLAKELGP
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
RGIGVNTIAPGAIETDFGGGSVRDNKQVNDFIASVTALGRPGLPDDIGPAVASLLTEDNR
CCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC
WINAQRIEVSGGMFV
EEEEEEEEECCCCCC
>Mature Secondary Structure 
TTNETKIALVTGASRGLGRSMAIALAHKGVDVIGTYHSNKAEADATVAAVEALGRKAVM
CCCCEEEEEEECCCCCCCHHHEEHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEE
FQLDTSNTASFASFAVDLKQRLAANWNRSTFDYLVNNAGIGIYAPFAETSEADFDRLMNI
EEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHH
HLKGVFFLTQALLPLIADGGRIVNLSSGLTRFSLPGYAAYAAMKGAVEVLTRYLAKELGP
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
RGIGVNTIAPGAIETDFGGGSVRDNKQVNDFIASVTALGRPGLPDDIGPAVASLLTEDNR
CCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC
WINAQRIEVSGGMFV
EEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 15.4 {2-deoxygluconate}} [C]

Substrates: @DEOX03.txt*2-Deoxy-D-Gluconate!; NAD(+) [C]

Specific reaction: @DEOX03.txt*2-Deoxy-D-Gluconate! + NAD(+) = @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate! + NADH. [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8868443 [H]