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The map label for this gene is gpmA

Identifier: 182677490

GI number: 182677490

Start: 552873

End: 553496

Strand: Direct

Name: gpmA

Synonym: Bind_0494

Alternate gene names: 182677490

Gene position: 552873-553496 (Clockwise)

Preceding gene: 182677489

Following gene: 182677491

Centisome position: 13.26

GC content: 55.93

Gene sequence:

>624_bases
ATGGATCGTCTTCTCGTGCTGGTGCGCCATGGTCAAAGCGATTGGAATTTAAAGAACCTCTTCACGGGGTGGAAGGATCC
GGATCTAACGGAAAAGGGCATTGGAGAAGCTCAGGCGGCGGGGCGTGGTCTCAAGGCGAAAGGTCTTGCGTTCGATATTG
CCTTTACATCCGCTCTGACACGCGCGCAGCACACATTGAAATTGATCCTCGGCGAATTGGGAACGCCCGATGTGCCGACG
ACGCGCGAACAGGCGCTCAATGAGCGTGATTACGGTGATCTCTCCGGGCTGAACAAGGATGATGCACGACAGAAATGGGG
CGAGGAGCAAGTCCATGTCTGGCGGCGTTCCTATGATATCTCGCCCCCCGGTGGTGAGAGCCTGAAGGATACAGTGGCGC
GGGTCTTGCCTTATTACTGCCAGAGCATTTTGCCGGCCGTGCTCGATGGCAAAAAAACCATTGTCGCCGCGCATGGCAAT
TCCCTGCGAGCCCTCGTGATGGTGCTTGACGGATTGACGCCAGAGACCATCCCCTCGATGGAACTTGAGACCGGTGTGCC
GTTGATTTATCGCCTGCGCGCTAATTCGACGGTTGAAAGCAAGGAAGTTCTGAAACTGGGCTGA

Upstream 100 bases:

>100_bases
GCGTCGATCCGATTATGCCTCGGCAATCATCAGGGTTCCTGTTCTGCGGAAGATCGGATAGTTCCGATCTGCTTTTGGGT
CTTTCTGTAAGGGATGCGCT

Downstream 100 bases:

>100_bases
GGCCGAAGATCGCTATTCGCGATCCTTGGCAGCTTATTGAAACAAAGCATCGGGCATGATCCGATGCTTTTCGCGATTTG
CGCCACAAACTTTAATATTT

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MDRLLVLVRHGQSDWNLKNLFTGWKDPDLTEKGIGEAQAAGRGLKAKGLAFDIAFTSALTRAQHTLKLILGELGTPDVPT
TREQALNERDYGDLSGLNKDDARQKWGEEQVHVWRRSYDISPPGGESLKDTVARVLPYYCQSILPAVLDGKKTIVAAHGN
SLRALVMVLDGLTPETIPSMELETGVPLIYRLRANSTVESKEVLKLG

Sequences:

>Translated_207_residues
MDRLLVLVRHGQSDWNLKNLFTGWKDPDLTEKGIGEAQAAGRGLKAKGLAFDIAFTSALTRAQHTLKLILGELGTPDVPT
TREQALNERDYGDLSGLNKDDARQKWGEEQVHVWRRSYDISPPGGESLKDTVARVLPYYCQSILPAVLDGKKTIVAAHGN
SLRALVMVLDGLTPETIPSMELETGVPLIYRLRANSTVESKEVLKLG
>Mature_207_residues
MDRLLVLVRHGQSDWNLKNLFTGWKDPDLTEKGIGEAQAAGRGLKAKGLAFDIAFTSALTRAQHTLKLILGELGTPDVPT
TREQALNERDYGDLSGLNKDDARQKWGEEQVHVWRRSYDISPPGGESLKDTVARVLPYYCQSILPAVLDGKKTIVAAHGN
SLRALVMVLDGLTPETIPSMELETGVPLIYRLRANSTVESKEVLKLG

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI4505753, Length=218, Percent_Identity=43.5779816513761, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI50593010, Length=215, Percent_Identity=42.7906976744186, Blast_Score=178, Evalue=3e-45,
Organism=Homo sapiens, GI4502445, Length=220, Percent_Identity=41.3636363636364, Blast_Score=169, Evalue=1e-42,
Organism=Homo sapiens, GI40353764, Length=220, Percent_Identity=41.3636363636364, Blast_Score=169, Evalue=1e-42,
Organism=Homo sapiens, GI71274132, Length=218, Percent_Identity=40.3669724770642, Blast_Score=167, Evalue=9e-42,
Organism=Homo sapiens, GI310129614, Length=160, Percent_Identity=43.75, Blast_Score=124, Evalue=6e-29,
Organism=Escherichia coli, GI1786970, Length=216, Percent_Identity=46.2962962962963, Blast_Score=194, Evalue=3e-51,
Organism=Escherichia coli, GI1786857, Length=183, Percent_Identity=27.8688524590164, Blast_Score=64, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322697, Length=216, Percent_Identity=41.2037037037037, Blast_Score=158, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6324516, Length=261, Percent_Identity=26.4367816091954, Blast_Score=98, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320183, Length=269, Percent_Identity=27.1375464684015, Blast_Score=93, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324857, Length=186, Percent_Identity=26.3440860215054, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI85725270, Length=219, Percent_Identity=44.7488584474886, Blast_Score=186, Evalue=8e-48,
Organism=Drosophila melanogaster, GI85725272, Length=219, Percent_Identity=44.7488584474886, Blast_Score=186, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24650981, Length=219, Percent_Identity=44.7488584474886, Blast_Score=186, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24646216, Length=216, Percent_Identity=43.5185185185185, Blast_Score=184, Evalue=5e-47,
Organism=Drosophila melanogaster, GI28571815, Length=216, Percent_Identity=34.2592592592593, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571817, Length=216, Percent_Identity=34.2592592592593, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24648979, Length=216, Percent_Identity=34.2592592592593, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_BEII9 (B2IEV6)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001831636.1
- ProteinModelPortal:   B2IEV6
- GeneID:   6201443
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_0494
- HOGENOM:   HBG658938
- OMA:   TGWKDPD
- ProtClustDB:   PRK01295
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 22774; Mature: 22774

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 10-10 ACT_SITE 158-158

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLLVLVRHGQSDWNLKNLFTGWKDPDLTEKGIGEAQAAGRGLKAKGLAFDIAFTSALT
CCCEEEEEECCCCCCCHHHHHCCCCCCCCCHHCCCHHHHHCCCCCCCCEEEHHHHHHHHH
RAQHTLKLILGELGTPDVPTTREQALNERDYGDLSGLNKDDARQKWGEEQVHVWRRSYDI
HHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHCCC
SPPGGESLKDTVARVLPYYCQSILPAVLDGKKTIVAAHGNSLRALVMVLDGLTPETIPSM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCC
ELETGVPLIYRLRANSTVESKEVLKLG
CCCCCCCEEEEECCCCCCCHHHHHCCC
>Mature Secondary Structure
MDRLLVLVRHGQSDWNLKNLFTGWKDPDLTEKGIGEAQAAGRGLKAKGLAFDIAFTSALT
CCCEEEEEECCCCCCCHHHHHCCCCCCCCCHHCCCHHHHHCCCCCCCCEEEHHHHHHHHH
RAQHTLKLILGELGTPDVPTTREQALNERDYGDLSGLNKDDARQKWGEEQVHVWRRSYDI
HHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHCCC
SPPGGESLKDTVARVLPYYCQSILPAVLDGKKTIVAAHGNSLRALVMVLDGLTPETIPSM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCC
ELETGVPLIYRLRANSTVESKEVLKLG
CCCCCCCEEEEECCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA