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The map label for this gene is ycaN [H]

Identifier: 182677459

GI number: 182677459

Start: 523752

End: 524654

Strand: Direct

Name: ycaN [H]

Synonym: Bind_0463

Alternate gene names: 182677459

Gene position: 523752-524654 (Clockwise)

Preceding gene: 182677448

Following gene: 182677461

Centisome position: 12.56

GC content: 59.36

Gene sequence:

>903_bases
ATGGACCGGCTGGACAACCTTTCGACTTTCGTCGCGGTCGCTGAGCAGGGCAGTTTCATTGCGGCTAGTCGTCAGCTCGG
TCGTTCTACGACCGCTGTGAGCCGTGCCGTCGCCGTGTTGGAGGATGTCTTGGGAACGCAACTCCTGACGCGAACCACGC
GCGCCGTTGCGTTGACGCAGGCAGGACAGCGCACTCTGGAGCAAGCGCGGCGCATTCTGGCTGATTATGCCCAGTTGCGG
GACGCGGCCGATGGAAATGCCACGCCATCTGGGCTCATCACGATAACCGCGCCGGAAATGTTTGGGCGCCTCCATGTATT
GCCCCTCGTGGAGAGCTTCATGGCGGCCCATAGCAACGTGGAGATTTCTCTTCTGTTGCTGAATCGGATGGTTTCGTTGA
TTGATGAGGGCGTAGATCTCGGTGTGCGTATCGCGCATTTATCTGACTCGAGCCTCCGAGCCATCCGGCTTGGCAGTGTG
CGACAAGTGCTATGCGCCAGTCCCGACTATCTCGCCATGGCCGGCACGCCATTGCATCCAAAAGACCTGGCTAACCATCG
GGTTATTGCCATCATGGGCGCGAGGCCCTTGCCTTTCCGGTGGCGCTTCAGGAGCAGTACAAATCCCCGATCCGTGCTCG
TCAAACCGCAACTCGTGGTGAATTCAGTGCAGGCCGCGTTGGAGGCTGCGTCGCGCGGAGCAGGAATTACACGTGTTCTT
TCTTATCAATCAGCGCCGCTGGAAGAAATCGGGGCGTTGCGGCGCCTGCTTATAGCGCACGAGCCGCCCTCCATCCCCAT
CCATCTTGTCTATCCCGTCGGTCGGTATCTTCCGTCGCGCATTCGCATGTTCATCGATCATGCCGTCGCTGCGCTTCGCG
GGCGCTTTCCAGAAGTCGAATGA

Upstream 100 bases:

>100_bases
TGCCAGGGCCAAAGCGGGCTTGCAGCACTATACGGTACGGCGACAACCGGGATAATTGAGGAGCTTTGGCACACTCTGTC
GCTAAAATCAGGATAATTCG

Downstream 100 bases:

>100_bases
GGCGTTTGATGATCTGATGGGATAGGGAGGGCCGATCGTTAATTGCTCTGCTCTCTCATTGATCACCCTTCTGCCGCGAG
ATCGAAAGCGCCACGATCGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MDRLDNLSTFVAVAEQGSFIAASRQLGRSTTAVSRAVAVLEDVLGTQLLTRTTRAVALTQAGQRTLEQARRILADYAQLR
DAADGNATPSGLITITAPEMFGRLHVLPLVESFMAAHSNVEISLLLLNRMVSLIDEGVDLGVRIAHLSDSSLRAIRLGSV
RQVLCASPDYLAMAGTPLHPKDLANHRVIAIMGARPLPFRWRFRSSTNPRSVLVKPQLVVNSVQAALEAASRGAGITRVL
SYQSAPLEEIGALRRLLIAHEPPSIPIHLVYPVGRYLPSRIRMFIDHAVAALRGRFPEVE

Sequences:

>Translated_300_residues
MDRLDNLSTFVAVAEQGSFIAASRQLGRSTTAVSRAVAVLEDVLGTQLLTRTTRAVALTQAGQRTLEQARRILADYAQLR
DAADGNATPSGLITITAPEMFGRLHVLPLVESFMAAHSNVEISLLLLNRMVSLIDEGVDLGVRIAHLSDSSLRAIRLGSV
RQVLCASPDYLAMAGTPLHPKDLANHRVIAIMGARPLPFRWRFRSSTNPRSVLVKPQLVVNSVQAALEAASRGAGITRVL
SYQSAPLEEIGALRRLLIAHEPPSIPIHLVYPVGRYLPSRIRMFIDHAVAALRGRFPEVE
>Mature_300_residues
MDRLDNLSTFVAVAEQGSFIAASRQLGRSTTAVSRAVAVLEDVLGTQLLTRTTRAVALTQAGQRTLEQARRILADYAQLR
DAADGNATPSGLITITAPEMFGRLHVLPLVESFMAAHSNVEISLLLLNRMVSLIDEGVDLGVRIAHLSDSSLRAIRLGSV
RQVLCASPDYLAMAGTPLHPKDLANHRVIAIMGARPLPFRWRFRSSTNPRSVLVKPQLVVNSVQAALEAASRGAGITRVL
SYQSAPLEEIGALRRLLIAHEPPSIPIHLVYPVGRYLPSRIRMFIDHAVAALRGRFPEVE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787128, Length=288, Percent_Identity=30.5555555555556, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=29.4520547945205, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081978, Length=235, Percent_Identity=34.8936170212766, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786401, Length=284, Percent_Identity=33.4507042253521, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI145693193, Length=305, Percent_Identity=30.1639344262295, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787589, Length=284, Percent_Identity=30.6338028169014, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789639, Length=307, Percent_Identity=30.2931596091205, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI145693105, Length=193, Percent_Identity=27.4611398963731, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082132, Length=289, Percent_Identity=23.8754325259516, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082024, Length=195, Percent_Identity=28.7179487179487, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI2367136, Length=291, Percent_Identity=26.1168384879725, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32638; Mature: 32638

Theoretical pI: Translated: 10.86; Mature: 10.86

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLDNLSTFVAVAEQGSFIAASRQLGRSTTAVSRAVAVLEDVLGTQLLTRTTRAVALTQ
CCCHHHHHHHHHHHCCCCEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGQRTLEQARRILADYAQLRDAADGNATPSGLITITAPEMFGRLHVLPLVESFMAAHSNV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHCHHHHHHHHHHHHHHCCCC
EISLLLLNRMVSLIDEGVDLGVRIAHLSDSSLRAIRLGSVRQVLCASPDYLAMAGTPLHP
EEHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEHHHHHHHHHCCCCEEEECCCCCCH
KDLANHRVIAIMGARPLPFRWRFRSSTNPRSVLVKPQLVVNSVQAALEAASRGAGITRVL
HHHCCCEEEEEECCCCCCEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHH
SYQSAPLEEIGALRRLLIAHEPPSIPIHLVYPVGRYLPSRIRMFIDHAVAALRGRFPEVE
HCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDRLDNLSTFVAVAEQGSFIAASRQLGRSTTAVSRAVAVLEDVLGTQLLTRTTRAVALTQ
CCCHHHHHHHHHHHCCCCEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGQRTLEQARRILADYAQLRDAADGNATPSGLITITAPEMFGRLHVLPLVESFMAAHSNV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHCHHHHHHHHHHHHHHCCCC
EISLLLLNRMVSLIDEGVDLGVRIAHLSDSSLRAIRLGSVRQVLCASPDYLAMAGTPLHP
EEHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEHHHHHHHHHCCCCEEEECCCCCCH
KDLANHRVIAIMGARPLPFRWRFRSSTNPRSVLVKPQLVVNSVQAALEAASRGAGITRVL
HHHCCCEEEEEECCCCCCEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHH
SYQSAPLEEIGALRRLLIAHEPPSIPIHLVYPVGRYLPSRIRMFIDHAVAALRGRFPEVE
HCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]