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The map label for this gene is mtgA [H]

Identifier: 182677420

GI number: 182677420

Start: 478979

End: 479689

Strand: Direct

Name: mtgA [H]

Synonym: Bind_0424

Alternate gene names: 182677420

Gene position: 478979-479689 (Clockwise)

Preceding gene: 182677416

Following gene: 182677421

Centisome position: 11.49

GC content: 63.01

Gene sequence:

>711_bases
ATGGCTTTCCTGCCTTTCTCTCGGCTCTTCTCCATCCGCTCGGGCCGTTTCGCTCGCTTCGTGTTCGGTGTCCTGCTGAC
GCTCGGCCTCGTGCTCGGCAGCCTGCTCGTCGCTTATCGCTTTCTGGCACCGGTCTCGACCTTGATGGCGTGGCACGAGA
TTAAAGGGGACGAAGTGGATCGCCACTACCAGCCCCTCGCACGCATCGCGCCGATTCTGGCCGCTTCCGTCATCGCTTCG
GAAGATGCGCGCTTTTGCCAGCATCACGGGGTCGACTGGCAGTCTCTCTCGGAGGTGATGGACAAGGCCAAGGCCCGGGC
AGACGGGCCCTCGCGCGGTGCCTCGACGATCACTATGCAGACCGCCAAGAACCTCTTCCTCTGGCCTTCGCGTTCCGTCC
TGCGCAAAACATTGGAAATTCCGCTGGCCTTGCTCATCGACGCGGTATGGCCGAAGCGGCGCATTCTGGAAATCTATTTG
AATATCGCCGAATGGGGCGATGGTCTCTTTGGTGCGGAGGCGGCGGCCCGGCATTATTTCGGCAAAAGCGCCGATGCACT
TGACCGGCGCGAGGCTGCGCTGCTTGCCACCGCCTTGCCCAATCCGATGCGGCGAAATCCCGCCTCTCCGACGCGGCTGC
ATCGCCTGCTCGCGGCGCGAATCGCCGCCCGCGCGGGCGCCATGGGCGCGGATATTACCTGTCTGAAATGA

Upstream 100 bases:

>100_bases
TGAAAATCTTCCGCCAGGGTGCCGCCGGTCATTGTCTCTCCCTATACCAAGGTGGAGGTTCGGCTTGCCCCATCGAGCCG
GATCGGTCAAGGCTCAAGCC

Downstream 100 bases:

>100_bases
TCGGCTGCGATGGGAAGCGCTGATTTTTCCATCTCGCTCTAGCCAGGGGCCGGTTTTTTGTGTAATAGGCGCCTTCCAGT
TCAAAGGTGCGGTCCTTCCG

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MAFLPFSRLFSIRSGRFARFVFGVLLTLGLVLGSLLVAYRFLAPVSTLMAWHEIKGDEVDRHYQPLARIAPILAASVIAS
EDARFCQHHGVDWQSLSEVMDKAKARADGPSRGASTITMQTAKNLFLWPSRSVLRKTLEIPLALLIDAVWPKRRILEIYL
NIAEWGDGLFGAEAAARHYFGKSADALDRREAALLATALPNPMRRNPASPTRLHRLLAARIAARAGAMGADITCLK

Sequences:

>Translated_236_residues
MAFLPFSRLFSIRSGRFARFVFGVLLTLGLVLGSLLVAYRFLAPVSTLMAWHEIKGDEVDRHYQPLARIAPILAASVIAS
EDARFCQHHGVDWQSLSEVMDKAKARADGPSRGASTITMQTAKNLFLWPSRSVLRKTLEIPLALLIDAVWPKRRILEIYL
NIAEWGDGLFGAEAAARHYFGKSADALDRREAALLATALPNPMRRNPASPTRLHRLLAARIAARAGAMGADITCLK
>Mature_235_residues
AFLPFSRLFSIRSGRFARFVFGVLLTLGLVLGSLLVAYRFLAPVSTLMAWHEIKGDEVDRHYQPLARIAPILAASVIASE
DARFCQHHGVDWQSLSEVMDKAKARADGPSRGASTITMQTAKNLFLWPSRSVLRKTLEIPLALLIDAVWPKRRILEIYLN
IAEWGDGLFGAEAAARHYFGKSADALDRREAALLATALPNPMRRNPASPTRLHRLLAARIAARAGAMGADITCLK

Specific function: Cell wall formation [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family [H]

Homologues:

Organism=Escherichia coli, GI1789601, Length=166, Percent_Identity=48.7951807228916, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI87082258, Length=193, Percent_Identity=35.7512953367876, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786343, Length=156, Percent_Identity=35.2564102564103, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001264
- InterPro:   IPR011812 [H]

Pfam domain/function: PF00912 Transgly [H]

EC number: 2.4.2.- [C]

Molecular weight: Translated: 26045; Mature: 25914

Theoretical pI: Translated: 10.83; Mature: 10.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFLPFSRLFSIRSGRFARFVFGVLLTLGLVLGSLLVAYRFLAPVSTLMAWHEIKGDEVD
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RHYQPLARIAPILAASVIASEDARFCQHHGVDWQSLSEVMDKAKARADGPSRGASTITMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEHH
TAKNLFLWPSRSVLRKTLEIPLALLIDAVWPKRRILEIYLNIAEWGDGLFGAEAAARHYF
HHCCEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
GKSADALDRREAALLATALPNPMRRNPASPTRLHRLLAARIAARAGAMGADITCLK
CCCCHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECC
>Mature Secondary Structure 
AFLPFSRLFSIRSGRFARFVFGVLLTLGLVLGSLLVAYRFLAPVSTLMAWHEIKGDEVD
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RHYQPLARIAPILAASVIASEDARFCQHHGVDWQSLSEVMDKAKARADGPSRGASTITMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEHH
TAKNLFLWPSRSVLRKTLEIPLALLIDAVWPKRRILEIYLNIAEWGDGLFGAEAAARHYF
HHCCEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
GKSADALDRREAALLATALPNPMRRNPASPTRLHRLLAARIAARAGAMGADITCLK
CCCCHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]