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The map label for this gene is moxY [H]

Identifier: 182677299

GI number: 182677299

Start: 344894

End: 346576

Strand: Direct

Name: moxY [H]

Synonym: Bind_0302

Alternate gene names: 182677299

Gene position: 344894-346576 (Clockwise)

Preceding gene: 182677290

Following gene: 182677301

Centisome position: 8.27

GC content: 60.43

Gene sequence:

>1683_bases
TTGTTGCATGGACGCGCCGGACAGGCGCGCCAAGACCCGCGCGGAGTTTTGCTCCGTCGGTCGTCTCATCTCAAGCTTGG
CGTCATATCGTTGGAAGCAATAACGTCCATCTCTTCGCAAGGCAACCAGGGAAGCGCCGGCAGGCCCCGCATCCAAGCGG
CCAAAAGTTCACTGCGGCTGGCTTTGCTCGTTATTCCTTCCGCCATACTTTGCCTCGCTATCCTCATTGCGATCGGAGTC
ACGCTTCTGGACGCAAGGGGTCGCATTGTCACGGAAACGGCGTCAGGACTCAATTTGGGCGATCTCGTCCTTTCCCATGC
TTTGCACGATCTCACGAGGGACCCAGACCCCGAGGCTGCGCTGATCAAACTGCGGCGGGATCTCTCCCGCCTGCGGCATA
TTTCTCTCCGCTTCGTCAGTGATCCGGCCCTGGGCGGCAACGAACACGAGGGGGACGCGCCGTCAGGGGGGAAGAACCAG
GACACGCCAGGTCCTGCTGATACCCCCCTCGTTCCTTGGCCCGAGCCGAGCCGGAGAGCCACGCGCGCCGCGCCGCTCTG
GTTCGAGGCCATGTTCGAACCGGCGCGGATCGTCAAAACCTATCCTGTCGTGCTGTCCCTGGCGGGGGACACGGAAAAAA
TCAGGGGTTCTTTCGTCATGGCGACACGCCCCGGTGACGAAGTGGCCGAGGTCTGGCGAGACCTCGTTTTTCTGACCGGA
CTTCTTGGCTGTCTGTCGCTGATCATCGTCGGGCTCATCGCGCTTTGTACGCATCAGGCCTTGCGGCTGTTCCATCAATT
GGTGGAAGGACTTGACCGGTTGGGACGCGGCCAGTTCGCGGCCATGACCGAATTTCCGGTTCAAGAACTCGCCCAGATCG
GCATGCATTTCAACCAGCTCGCGGCCACGCTCGAGCGCAGCGAGGTGGACAAACATCATTTGATCGATCGGCTGATTTCC
GTCCAGGAAAGCGAACGCAAGGAACTCGCCCGCGAATTGCACGATGAATATGGCGCGGCGCTCTTCGGCATCCGGGCGGC
CACCTCCTGCATCCTCGACTCGGCGCATGCCTTGCAGCGGCCCGAACCCGGGGAGAACCAAAACATTCAAGAGATTAGCG
AACGCGCCCAGGCGATTTCCCAGCTCGCCGATACGATCCAGAAACAGAATCGTCGCATTCTTGAACGGATCCGCCCCGCT
GTCCTGCATCGGATGGGTCTGCCCGAGGCCCTGCGCCATCTTGTCGAGGATTGGCAAACGCATCACAAAGGTTTCTCCTG
TGCCCTGACCCTTGCGGTGGACTCGGCGAGTTTCGATGAAGAGGTGAGCCTGACCTTTTATCGCCTGGTGCAGGAATGCC
TGACCAATATAGCGCGGCATTCGCAAGCCCGATCGGCCCGGATCACGCTGGCACTCGTTGCCGCTTCGGCACACCCGGAG
GAGGGTGTTTCAGAGCCGGGCCAAAATCTCTGCCTGCGGATCGAGGATGACGGGATCGGCCTGCCGCCGTCTTTCCGGTT
CGGTTTCGGTTTCCTCGGCATGAGCGAAAGGGTCCGCAAGCTTGCCGGGTGCTTGCGGATCGAAAACGCCTTGCCCCACG
GCACATTAATCGAGGCGCTTATTCCGCTGCCTCGTTCTTCTTATGCCAAGTCTCACCCTTGGTATGAGGCATCGAACCCA
TAA

Upstream 100 bases:

>100_bases
CGGCTCCCAAGGAACGGCGTGGAAAGCGAGCTCGCTTTCGCTTATCCGCATCCTTGGACGAACCGCGAAAGGATGATTGA
AAAAAGGAAGTTACCAGGAT

Downstream 100 bases:

>100_bases
GTTTGCTACAGCTTCCGGAACATCACCAATGCATCCACATCCCCCAATGTGGGATGGGCAAAGGCGCCGGGCAGAGCGCC
GATAATATCAAATCCGAGAG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MLHGRAGQARQDPRGVLLRRSSHLKLGVISLEAITSISSQGNQGSAGRPRIQAAKSSLRLALLVIPSAILCLAILIAIGV
TLLDARGRIVTETASGLNLGDLVLSHALHDLTRDPDPEAALIKLRRDLSRLRHISLRFVSDPALGGNEHEGDAPSGGKNQ
DTPGPADTPLVPWPEPSRRATRAAPLWFEAMFEPARIVKTYPVVLSLAGDTEKIRGSFVMATRPGDEVAEVWRDLVFLTG
LLGCLSLIIVGLIALCTHQALRLFHQLVEGLDRLGRGQFAAMTEFPVQELAQIGMHFNQLAATLERSEVDKHHLIDRLIS
VQESERKELARELHDEYGAALFGIRAATSCILDSAHALQRPEPGENQNIQEISERAQAISQLADTIQKQNRRILERIRPA
VLHRMGLPEALRHLVEDWQTHHKGFSCALTLAVDSASFDEEVSLTFYRLVQECLTNIARHSQARSARITLALVAASAHPE
EGVSEPGQNLCLRIEDDGIGLPPSFRFGFGFLGMSERVRKLAGCLRIENALPHGTLIEALIPLPRSSYAKSHPWYEASNP

Sequences:

>Translated_560_residues
MLHGRAGQARQDPRGVLLRRSSHLKLGVISLEAITSISSQGNQGSAGRPRIQAAKSSLRLALLVIPSAILCLAILIAIGV
TLLDARGRIVTETASGLNLGDLVLSHALHDLTRDPDPEAALIKLRRDLSRLRHISLRFVSDPALGGNEHEGDAPSGGKNQ
DTPGPADTPLVPWPEPSRRATRAAPLWFEAMFEPARIVKTYPVVLSLAGDTEKIRGSFVMATRPGDEVAEVWRDLVFLTG
LLGCLSLIIVGLIALCTHQALRLFHQLVEGLDRLGRGQFAAMTEFPVQELAQIGMHFNQLAATLERSEVDKHHLIDRLIS
VQESERKELARELHDEYGAALFGIRAATSCILDSAHALQRPEPGENQNIQEISERAQAISQLADTIQKQNRRILERIRPA
VLHRMGLPEALRHLVEDWQTHHKGFSCALTLAVDSASFDEEVSLTFYRLVQECLTNIARHSQARSARITLALVAASAHPE
EGVSEPGQNLCLRIEDDGIGLPPSFRFGFGFLGMSERVRKLAGCLRIENALPHGTLIEALIPLPRSSYAKSHPWYEASNP
>Mature_560_residues
MLHGRAGQARQDPRGVLLRRSSHLKLGVISLEAITSISSQGNQGSAGRPRIQAAKSSLRLALLVIPSAILCLAILIAIGV
TLLDARGRIVTETASGLNLGDLVLSHALHDLTRDPDPEAALIKLRRDLSRLRHISLRFVSDPALGGNEHEGDAPSGGKNQ
DTPGPADTPLVPWPEPSRRATRAAPLWFEAMFEPARIVKTYPVVLSLAGDTEKIRGSFVMATRPGDEVAEVWRDLVFLTG
LLGCLSLIIVGLIALCTHQALRLFHQLVEGLDRLGRGQFAAMTEFPVQELAQIGMHFNQLAATLERSEVDKHHLIDRLIS
VQESERKELARELHDEYGAALFGIRAATSCILDSAHALQRPEPGENQNIQEISERAQAISQLADTIQKQNRRILERIRPA
VLHRMGLPEALRHLVEDWQTHHKGFSCALTLAVDSASFDEEVSLTFYRLVQECLTNIARHSQARSARITLALVAASAHPE
EGVSEPGQNLCLRIEDDGIGLPPSFRFGFGFLGMSERVRKLAGCLRIENALPHGTLIEALIPLPRSSYAKSHPWYEASNP

Specific function: Member of the two-component regulatory system moxY/moxX probably involved in the regulation of the methanol dehydrogenase expression. May function as a membrane-associated protein kinase that phosphorylates moxX in response to environmental signals [H]

COG id: COG3851

COG function: function code T; Signal transduction histidine kinase, glucose-6-phosphate specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=245, Percent_Identity=33.0612244897959, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR011712 [H]

Pfam domain/function: PF00672 HAMP; PF07730 HisKA_3 [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 61399; Mature: 61399

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHGRAGQARQDPRGVLLRRSSHLKLGVISLEAITSISSQGNQGSAGRPRIQAAKSSLRL
CCCCCCCCCCCCCCHHEEECCCCCEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
ALLVIPSAILCLAILIAIGVTLLDARGRIVTETASGLNLGDLVLSHALHDLTRDPDPEAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHH
LIKLRRDLSRLRHISLRFVSDPALGGNEHEGDAPSGGKNQDTPGPADTPLVPWPEPSRRA
HHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
TRAAPLWFEAMFEPARIVKTYPVVLSLAGDTEKIRGSFVMATRPGDEVAEVWRDLVFLTG
HHCCHHHHHHHHCHHHHHHHHHHHEEECCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHH
LLGCLSLIIVGLIALCTHQALRLFHQLVEGLDRLGRGQFAAMTEFPVQELAQIGMHFNQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHH
AATLERSEVDKHHLIDRLISVQESERKELARELHDEYGAALFGIRAATSCILDSAHALQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEPGENQNIQEISERAQAISQLADTIQKQNRRILERIRPAVLHRMGLPEALRHLVEDWQT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
HHKGFSCALTLAVDSASFDEEVSLTFYRLVQECLTNIARHSQARSARITLALVAASAHPE
HCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCC
EGVSEPGQNLCLRIEDDGIGLPPSFRFGFGFLGMSERVRKLAGCLRIENALPHGTLIEAL
CCCCCCCCCCEEEECCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
IPLPRSSYAKSHPWYEASNP
HCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLHGRAGQARQDPRGVLLRRSSHLKLGVISLEAITSISSQGNQGSAGRPRIQAAKSSLRL
CCCCCCCCCCCCCCHHEEECCCCCEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
ALLVIPSAILCLAILIAIGVTLLDARGRIVTETASGLNLGDLVLSHALHDLTRDPDPEAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHH
LIKLRRDLSRLRHISLRFVSDPALGGNEHEGDAPSGGKNQDTPGPADTPLVPWPEPSRRA
HHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
TRAAPLWFEAMFEPARIVKTYPVVLSLAGDTEKIRGSFVMATRPGDEVAEVWRDLVFLTG
HHCCHHHHHHHHCHHHHHHHHHHHEEECCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHH
LLGCLSLIIVGLIALCTHQALRLFHQLVEGLDRLGRGQFAAMTEFPVQELAQIGMHFNQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHH
AATLERSEVDKHHLIDRLISVQESERKELARELHDEYGAALFGIRAATSCILDSAHALQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEPGENQNIQEISERAQAISQLADTIQKQNRRILERIRPAVLHRMGLPEALRHLVEDWQT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
HHKGFSCALTLAVDSASFDEEVSLTFYRLVQECLTNIARHSQARSARITLALVAASAHPE
HCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCC
EGVSEPGQNLCLRIEDDGIGLPPSFRFGFGFLGMSERVRKLAGCLRIENALPHGTLIEAL
CCCCCCCCCCEEEECCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
IPLPRSSYAKSHPWYEASNP
HCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8392137 [H]