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The map label for this gene is ribH

Identifier: 182677205

GI number: 182677205

Start: 243740

End: 244285

Strand: Direct

Name: ribH

Synonym: Bind_0206

Alternate gene names: 182677205

Gene position: 243740-244285 (Clockwise)

Preceding gene: 182677202

Following gene: 182677206

Centisome position: 5.84

GC content: 61.9

Gene sequence:

>546_bases
ATGGCCGAGCCACGGCGAGCCCTTGCCCAAATGGATGATGCGAGAATCAGCGTTGGTAACGCGCGGTTTCTGATCATCGA
GGCGCCTTATTATGAAGATATTGCCGCGCAGCTGCGTGCCGGTGCCGAGGCGGCGCTGACACGAGCGCAAGCGCGTTTCG
ATGTCGTGAGCGTGCCGGGCGCGCTTGAAATCCCCATAGCGCTCGCCATTGCGCTGGATCGCGCGCCAGCCCTTTATCAG
GGGGCGATCGCGCTTGGCTGCATCATCCGGGGCGAGACCTATCATTTTGAAATCGTCGCCAACGAAAGCGCGCGAGCCCT
GACGCAGCTTGTGGTGGAGCGCAAACTGCCTTTCGGCAATGGTATCCTGACCGTTGAAACCGAGACGCAGGCCCTCGAAC
GTGCCTCGGTCGAAAGTGGTGACAAGGGGGGAGATGCCGCACGCGCGGCATTGGCGCTCTACCGGTTCAGCCAGGAATTC
GGTCAAGTCGTCGAGCAAGCCCAGATTCAAGCTCAGCGCCCGGTCCTGACCTCGGGAGCGCGCTAA

Upstream 100 bases:

>100_bases
AAGGCTTGTTACTCGATGCGCGCGAATCGGATCGGTCTTGAGTTCTGTCTCGTCCTCCGATCTTTATCCTTCATCTGATC
TTTGACCCCCGAGTGCGACG

Downstream 100 bases:

>100_bases
TGGCCCCGATCCCACCCTTGGGAGGGTTGTAATGGCTAATGCCGAACAGCGCTCCGCCGCTCGCCTTGCCGCGGTCCAGG
CGCTCTACCAGATGGAAGTC

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MAEPRRALAQMDDARISVGNARFLIIEAPYYEDIAAQLRAGAEAALTRAQARFDVVSVPGALEIPIALAIALDRAPALYQ
GAIALGCIIRGETYHFEIVANESARALTQLVVERKLPFGNGILTVETETQALERASVESGDKGGDAARAALALYRFSQEF
GQVVEQAQIQAQRPVLTSGAR

Sequences:

>Translated_181_residues
MAEPRRALAQMDDARISVGNARFLIIEAPYYEDIAAQLRAGAEAALTRAQARFDVVSVPGALEIPIALAIALDRAPALYQ
GAIALGCIIRGETYHFEIVANESARALTQLVVERKLPFGNGILTVETETQALERASVESGDKGGDAARAALALYRFSQEF
GQVVEQAQIQAQRPVLTSGAR
>Mature_180_residues
AEPRRALAQMDDARISVGNARFLIIEAPYYEDIAAQLRAGAEAALTRAQARFDVVSVPGALEIPIALAIALDRAPALYQG
AIALGCIIRGETYHFEIVANESARALTQLVVERKLPFGNGILTVETETQALERASVESGDKGGDAARAALALYRFSQEFG
QVVEQAQIQAQRPVLTSGAR

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=145, Percent_Identity=38.6206896551724, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_BEII9 (B2ICH3)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001831351.1
- GeneID:   6198312
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_0206
- HOGENOM:   HBG311126
- OMA:   EQANERS
- ProtClustDB:   CLSK2405154
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 19408; Mature: 19277

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPRRALAQMDDARISVGNARFLIIEAPYYEDIAAQLRAGAEAALTRAQARFDVVSVPG
CCCHHHHHHHCCCCEEEECCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHEEEEECCC
ALEIPIALAIALDRAPALYQGAIALGCIIRGETYHFEIVANESARALTQLVVERKLPFGN
CEEHHEEEEEECCCCCHHHHHHHHEEEEEECCEEEEEEEECCHHHHHHHHHHHHCCCCCC
GILTVETETQALERASVESGDKGGDAARAALALYRFSQEFGQVVEQAQIQAQRPVLTSGA
CEEEEECHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
R
C
>Mature Secondary Structure 
AEPRRALAQMDDARISVGNARFLIIEAPYYEDIAAQLRAGAEAALTRAQARFDVVSVPG
CCHHHHHHHCCCCEEEECCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHEEEEECCC
ALEIPIALAIALDRAPALYQGAIALGCIIRGETYHFEIVANESARALTQLVVERKLPFGN
CEEHHEEEEEECCCCCHHHHHHHHEEEEEECCEEEEEEEECCHHHHHHHHHHHHCCCCCC
GILTVETETQALERASVESGDKGGDAARAALALYRFSQEFGQVVEQAQIQAQRPVLTSGA
CEEEEECHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA