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The map label for this gene is ackA [H]

Identifier: 182677198

GI number: 182677198

Start: 234723

End: 235949

Strand: Direct

Name: ackA [H]

Synonym: Bind_0199

Alternate gene names: 182677198

Gene position: 234723-235949 (Clockwise)

Preceding gene: 182677191

Following gene: 182677202

Centisome position: 5.63

GC content: 56.81

Gene sequence:

>1227_bases
ATGACCCAAGCTCTTCTCGTCGTCAATGCTGGCAGCTCCAGCATTAAATTCAAGCTTTATAGCGTCAATGGCGATGATCT
TGACCTCGTCATGGGCGGGGCGCTCGATGGAATCGGCAGTCAGCCCCGTCTCAAGGTCAAGGATCACGCAGGCACCATAT
TGGTGGAGCATGATTATGCCGTGGCGGAGATTTCGACCACGGAGCAGGCGCAAACAGCGATCGCTGATTGGCTCACGCCA
CACATCAAGGACTATGTGATCATTGGCATCGGTCATCGTGTCGTGCACGGTGGTTCTGTCTATTCCAGACCGGTTCTGGT
CGATGATCAGGTGATGGCGACGCTCGAAACCTTCATTCCGCTGGCGCCTTTGCATCAGCTCGGCAATCTCGATCCGATTC
GCGTTTTGCGCCAGCGCCGTCCCGACCTTCCGCAGGTCGCCTGTTTCGACACCGCTTTCCATTTTGGCCATCCGGAATTG
TCGGATCGTTTCGCATTGCCGCGCTCGCTTTATGACGAGGGGGTCCGGCGCTACGGTTTCCACGGTCTGTCTTATGAATA
TGTGCATGCGGCGCTGCGTGATATCGCGCCGGACACTGCCCATGGCCGTGTGATCATTGCCCATCTGGGTTCAGGTGCTT
CCGTCTGTTGTCTCCATGAGGGCAAGAGCATCGAAACGACGATGGGATTTACGGCGCTTGACGGCTTGCCCATGGGCACG
CGGTCGGGAACGCTGGATCCTGGTGTCGTGCTGCATTTGATCGAGCAGAAAGGCATGAAGCCGGCGGAAGTGGGCACGAT
GCTCTATAAGCAAAGTGGCCTGTTGGGTCTCTCCGGCATCAGCAATGATGTCCGTGCTTTGCTTGCAAGCGATCGCCCCG
AAGCCAAAATGGCGATTGATTTCTTCTGCTTGCGCGTGGCCCAGGCCATGGCGAGTCTCTCGGTCACCATCTATGGGCTT
GATGGCCTTGTCTTTACGGCGGGCATTGGCGAAAACGCACCGGAAGTGCGTGCCCGCGTCATCGAGCATTTACGCTGGTC
TGGTCTCGCTCTTGATCCTGCTGCTAATGAAGCGCCGGCCCCAAGTCATCAAAGGCAAGGCAACAAGGGCCGGCGGATCG
ATGGCAAAGAGAGCCGTGTGCCGATCTTTGTCATTCCGACGGATGAGGAACGTATGATCGGCCTGCATACATTGCGGCTG
TTGCGGCAGTTGAAACATCATTCCTGA

Upstream 100 bases:

>100_bases
ACTCCAAGAATGAGGAATCTCCTGAAATAGCGCGAATCCTCTCGCGTCTTCGGCCTGTTCGGCCTTTTACGAAACATCAG
CCGGTGGGAGTCTCGATTTC

Downstream 100 bases:

>100_bases
TAGCGGTCCGACGGTCATAATGAATGACCGTTGGACCGCTCTTGAATTTTCGCTCTCGCTTTGAAAAAGCGAAAATTCAA
GAAAGGAACCAAAGGTCGTT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MTQALLVVNAGSSSIKFKLYSVNGDDLDLVMGGALDGIGSQPRLKVKDHAGTILVEHDYAVAEISTTEQAQTAIADWLTP
HIKDYVIIGIGHRVVHGGSVYSRPVLVDDQVMATLETFIPLAPLHQLGNLDPIRVLRQRRPDLPQVACFDTAFHFGHPEL
SDRFALPRSLYDEGVRRYGFHGLSYEYVHAALRDIAPDTAHGRVIIAHLGSGASVCCLHEGKSIETTMGFTALDGLPMGT
RSGTLDPGVVLHLIEQKGMKPAEVGTMLYKQSGLLGLSGISNDVRALLASDRPEAKMAIDFFCLRVAQAMASLSVTIYGL
DGLVFTAGIGENAPEVRARVIEHLRWSGLALDPAANEAPAPSHQRQGNKGRRIDGKESRVPIFVIPTDEERMIGLHTLRL
LRQLKHHS

Sequences:

>Translated_408_residues
MTQALLVVNAGSSSIKFKLYSVNGDDLDLVMGGALDGIGSQPRLKVKDHAGTILVEHDYAVAEISTTEQAQTAIADWLTP
HIKDYVIIGIGHRVVHGGSVYSRPVLVDDQVMATLETFIPLAPLHQLGNLDPIRVLRQRRPDLPQVACFDTAFHFGHPEL
SDRFALPRSLYDEGVRRYGFHGLSYEYVHAALRDIAPDTAHGRVIIAHLGSGASVCCLHEGKSIETTMGFTALDGLPMGT
RSGTLDPGVVLHLIEQKGMKPAEVGTMLYKQSGLLGLSGISNDVRALLASDRPEAKMAIDFFCLRVAQAMASLSVTIYGL
DGLVFTAGIGENAPEVRARVIEHLRWSGLALDPAANEAPAPSHQRQGNKGRRIDGKESRVPIFVIPTDEERMIGLHTLRL
LRQLKHHS
>Mature_407_residues
TQALLVVNAGSSSIKFKLYSVNGDDLDLVMGGALDGIGSQPRLKVKDHAGTILVEHDYAVAEISTTEQAQTAIADWLTPH
IKDYVIIGIGHRVVHGGSVYSRPVLVDDQVMATLETFIPLAPLHQLGNLDPIRVLRQRRPDLPQVACFDTAFHFGHPELS
DRFALPRSLYDEGVRRYGFHGLSYEYVHAALRDIAPDTAHGRVIIAHLGSGASVCCLHEGKSIETTMGFTALDGLPMGTR
SGTLDPGVVLHLIEQKGMKPAEVGTMLYKQSGLLGLSGISNDVRALLASDRPEAKMAIDFFCLRVAQAMASLSVTIYGLD
GLVFTAGIGENAPEVRARVIEHLRWSGLALDPAANEAPAPSHQRQGNKGRRIDGKESRVPIFVIPTDEERMIGLHTLRLL
RQLKHHS

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=405, Percent_Identity=38.7654320987654, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1788633, Length=414, Percent_Identity=35.5072463768116, Blast_Score=211, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 44355; Mature: 44223

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQALLVVNAGSSSIKFKLYSVNGDDLDLVMGGALDGIGSQPRLKVKDHAGTILVEHDYA
CCCEEEEEECCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCCEEEECCCCEEEEECCCE
VAEISTTEQAQTAIADWLTPHIKDYVIIGIGHRVVHGGSVYSRPVLVDDQVMATLETFIP
EEEECCHHHHHHHHHHHHCCCCCCEEEEEECCEEEECCCCCCCCEEECHHHHHHHHHHCC
LAPLHQLGNLDPIRVLRQRRPDLPQVACFDTAFHFGHPELSDRFALPRSLYDEGVRRYGF
HHHHHHHCCCCHHHHHHHHCCCCCCEEEEHHHHHCCCCCCCHHHCCCHHHHHHHHHHHCC
HGLSYEYVHAALRDIAPDTAHGRVIIAHLGSGASVCCLHEGKSIETTMGFTALDGLPMGT
CCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCEEEECCEEEECCCCCCC
RSGTLDPGVVLHLIEQKGMKPAEVGTMLYKQSGLLGLSGISNDVRALLASDRPEAKMAID
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCCHHHHHH
FFCLRVAQAMASLSVTIYGLDGLVFTAGIGENAPEVRARVIEHLRWSGLALDPAANEAPA
HHHHHHHHHHHHEEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHCCEEECCCCCCCCC
PSHQRQGNKGRRIDGKESRVPIFVIPTDEERMIGLHTLRLLRQLKHHS
CCHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQALLVVNAGSSSIKFKLYSVNGDDLDLVMGGALDGIGSQPRLKVKDHAGTILVEHDYA
CCEEEEEECCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCCEEEECCCCEEEEECCCE
VAEISTTEQAQTAIADWLTPHIKDYVIIGIGHRVVHGGSVYSRPVLVDDQVMATLETFIP
EEEECCHHHHHHHHHHHHCCCCCCEEEEEECCEEEECCCCCCCCEEECHHHHHHHHHHCC
LAPLHQLGNLDPIRVLRQRRPDLPQVACFDTAFHFGHPELSDRFALPRSLYDEGVRRYGF
HHHHHHHCCCCHHHHHHHHCCCCCCEEEEHHHHHCCCCCCCHHHCCCHHHHHHHHHHHCC
HGLSYEYVHAALRDIAPDTAHGRVIIAHLGSGASVCCLHEGKSIETTMGFTALDGLPMGT
CCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCEEEECCEEEECCCCCCC
RSGTLDPGVVLHLIEQKGMKPAEVGTMLYKQSGLLGLSGISNDVRALLASDRPEAKMAID
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCCHHHHHH
FFCLRVAQAMASLSVTIYGLDGLVFTAGIGENAPEVRARVIEHLRWSGLALDPAANEAPA
HHHHHHHHHHHHEEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHCCEEECCCCCCCCC
PSHQRQGNKGRRIDGKESRVPIFVIPTDEERMIGLHTLRLLRQLKHHS
CCHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA