Click here to switch to the map view.

The map label for this gene is yhaO [H]

Identifier: 182677162

GI number: 182677162

Start: 190404

End: 191636

Strand: Direct

Name: yhaO [H]

Synonym: Bind_0161

Alternate gene names: 182677162

Gene position: 190404-191636 (Clockwise)

Preceding gene: 182677161

Following gene: 182677163

Centisome position: 4.57

GC content: 58.8

Gene sequence:

>1233_bases
ATGAAATTCAGCTTTCTCCACGCCGCCGACCTGCATCTTGGCAGCCCCTTGATCGGGCTGGCTGCCAAGGATGAGGACAT
TGCCCGGCAATTTGCCGCCGCGAGCCGCCAGGCTTTCTCCGACCTCGTTGCTTATGCGATCGAACAGCACATCGCCTTTG
TCGTCATCGCCGGCGATATTTATGATGGCGAATGGAAGGATTCCTCAATCGGTCTGTTCTTCAACCGTGAGCTTTCCCGC
CTCCATCGGGCTGGCATAGAGGTCGTAATCCTCAAGGGCAATCATGATGCAGCGAGCGTCGTGACGAAGACGATCACCTT
GCCGGAAAGTGTGTATGTCTTTCCGACCAATAAGGCTTCGACGTTCAGGCTCGATGATTACCGCGTCGCCTTGCATGGCC
GTAGCTTCCCGAACCGGGAAGTGAACGAGAATTATGTCGAGGCCTATCCTGAACCTGTCGCGGGCTGGTTCAATATTGGC
GTGCTGCATACATCCTGCGACGGCCGTCCGCCGCATGCGCGTTACGCGCCCTGCAGCCTTGATGACATGCGTCGCCATGG
CTATGATTATTGGGCGCTCGGCCATGTGCATGCGCATGAGATCTTGTGCGACGAACCCAAAATCGTCTTCGCGGGCAATT
TGCAAGGCCGCAGCATCAGGGAATGTGGTCCCAAGGGCGCGGTGCGTGTCGATGTCGAGGATCAGGCGATCAAGACCGTC
ACGCATATCCCCTTCGATCAGGCGCGTTTCGGCAAGCTGACGCTCGATCTCGGAAGCGTGGAGGAAGAGGCTGATCTCCT
CCGCCTTGTGGAAACAAACCTTGCGCCTTTCGTCAACGAGGCCGGGAAACGGCTCCTCGCTCTGCGCGTCGAATGTATAG
GCGAGACCAGCTTGCACCGCGCGCTCAAGGCAGATGCGCAAAGGTTGAGCGATGAAGTGCAGGCAGCGGCGCATCGCGTG
AGCGAAAATGTCTGGCTGGAAAAACTCGCGATTGCGACGCGCGAGCCTGCCTCGATGACGGGCATGACCGCCCCCTCCGA
TCTCGATCTCGCAGGTCTGTTCGCGGCCTGCGAGAAGGACCCGGTCCTGCGTGAAGATGTTGAGCAATTGATCAAGGATG
TCAGCCGCAAGCTGCCGCGCGGCTGTAGCGATCAGGGAGAGACACTCATGGCGGAGATTGATGCCTTGATCGAAGATGCC
CGTGCCTCGACGCTCGGCCGCGTCCTGCGTTAG

Upstream 100 bases:

>100_bases
GGGCGCCGCTGATCGACGCTCCATAACGGAAAGTGTGCATCCTTTTGGGAGCGGAACTGGCTGAGCGTCCGATGTCTTAA
ACCATGAGGTGCGGCGATCC

Downstream 100 bases:

>100_bases
ATGCGTTTTCGAAAGGCTGTGGATGCGTCTCCTCTCGCTCTCGCTTGAACGCTTCGGCCCCTTCACCGATCGCCTTCTGA
CCTTTCGTGAGGGCGCGAAA

Product: metallophosphoesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MKFSFLHAADLHLGSPLIGLAAKDEDIARQFAAASRQAFSDLVAYAIEQHIAFVVIAGDIYDGEWKDSSIGLFFNRELSR
LHRAGIEVVILKGNHDAASVVTKTITLPESVYVFPTNKASTFRLDDYRVALHGRSFPNREVNENYVEAYPEPVAGWFNIG
VLHTSCDGRPPHARYAPCSLDDMRRHGYDYWALGHVHAHEILCDEPKIVFAGNLQGRSIRECGPKGAVRVDVEDQAIKTV
THIPFDQARFGKLTLDLGSVEEEADLLRLVETNLAPFVNEAGKRLLALRVECIGETSLHRALKADAQRLSDEVQAAAHRV
SENVWLEKLAIATREPASMTGMTAPSDLDLAGLFAACEKDPVLREDVEQLIKDVSRKLPRGCSDQGETLMAEIDALIEDA
RASTLGRVLR

Sequences:

>Translated_410_residues
MKFSFLHAADLHLGSPLIGLAAKDEDIARQFAAASRQAFSDLVAYAIEQHIAFVVIAGDIYDGEWKDSSIGLFFNRELSR
LHRAGIEVVILKGNHDAASVVTKTITLPESVYVFPTNKASTFRLDDYRVALHGRSFPNREVNENYVEAYPEPVAGWFNIG
VLHTSCDGRPPHARYAPCSLDDMRRHGYDYWALGHVHAHEILCDEPKIVFAGNLQGRSIRECGPKGAVRVDVEDQAIKTV
THIPFDQARFGKLTLDLGSVEEEADLLRLVETNLAPFVNEAGKRLLALRVECIGETSLHRALKADAQRLSDEVQAAAHRV
SENVWLEKLAIATREPASMTGMTAPSDLDLAGLFAACEKDPVLREDVEQLIKDVSRKLPRGCSDQGETLMAEIDALIEDA
RASTLGRVLR
>Mature_410_residues
MKFSFLHAADLHLGSPLIGLAAKDEDIARQFAAASRQAFSDLVAYAIEQHIAFVVIAGDIYDGEWKDSSIGLFFNRELSR
LHRAGIEVVILKGNHDAASVVTKTITLPESVYVFPTNKASTFRLDDYRVALHGRSFPNREVNENYVEAYPEPVAGWFNIG
VLHTSCDGRPPHARYAPCSLDDMRRHGYDYWALGHVHAHEILCDEPKIVFAGNLQGRSIRECGPKGAVRVDVEDQAIKTV
THIPFDQARFGKLTLDLGSVEEEADLLRLVETNLAPFVNEAGKRLLALRVECIGETSLHRALKADAQRLSDEVQAAAHRV
SENVWLEKLAIATREPASMTGMTAPSDLDLAGLFAACEKDPVLREDVEQLIKDVSRKLPRGCSDQGETLMAEIDALIEDA
RASTLGRVLR

Specific function: Sbccd Cleaves DNA Hairpin Structures. These Structures Can Inhibit DNA Replication And Are Intermediates In Certain DNA Recombination Reactions. The Complex Acts As A 3'->5' Double Strand Exonuclease That Can Open Hairpins. It Also Has A 5' Single-Strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallophosphoesterase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR014576 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 45303; Mature: 45303

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSFLHAADLHLGSPLIGLAAKDEDIARQFAAASRQAFSDLVAYAIEQHIAFVVIAGDI
CCCEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCE
YDGEWKDSSIGLFFNRELSRLHRAGIEVVILKGNHDAASVVTKTITLPESVYVFPTNKAS
ECCCCCCCCEEEEECHHHHHHHHCCCEEEEEECCCCHHHHHEEEEECCCEEEEEECCCCC
TFRLDDYRVALHGRSFPNREVNENYVEAYPEPVAGWFNIGVLHTSCDGRPPHARYAPCSL
EEEECCEEEEEECCCCCCCCCCCHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCH
DDMRRHGYDYWALGHVHAHEILCDEPKIVFAGNLQGRSIRECGPKGAVRVDVEDQAIKTV
HHHHHCCCCEEEECCCCHHHEEECCCCEEEECCCCCCCHHHCCCCCCEEEECCHHHHHHH
THIPFDQARFGKLTLDLGSVEEEADLLRLVETNLAPFVNEAGKRLLALRVECIGETSLHR
HCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHCCCHHHHH
ALKADAQRLSDEVQAAAHRVSENVWLEKLAIATREPASMTGMTAPSDLDLAGLFAACEKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCC
PVLREDVEQLIKDVSRKLPRGCSDQGETLMAEIDALIEDARASTLGRVLR
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFSFLHAADLHLGSPLIGLAAKDEDIARQFAAASRQAFSDLVAYAIEQHIAFVVIAGDI
CCCEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCE
YDGEWKDSSIGLFFNRELSRLHRAGIEVVILKGNHDAASVVTKTITLPESVYVFPTNKAS
ECCCCCCCCEEEEECHHHHHHHHCCCEEEEEECCCCHHHHHEEEEECCCEEEEEECCCCC
TFRLDDYRVALHGRSFPNREVNENYVEAYPEPVAGWFNIGVLHTSCDGRPPHARYAPCSL
EEEECCEEEEEECCCCCCCCCCCHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCH
DDMRRHGYDYWALGHVHAHEILCDEPKIVFAGNLQGRSIRECGPKGAVRVDVEDQAIKTV
HHHHHCCCCEEEECCCCHHHEEECCCCEEEECCCCCCCHHHCCCCCCEEEECCHHHHHHH
THIPFDQARFGKLTLDLGSVEEEADLLRLVETNLAPFVNEAGKRLLALRVECIGETSLHR
HCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHCCCHHHHH
ALKADAQRLSDEVQAAAHRVSENVWLEKLAIATREPASMTGMTAPSDLDLAGLFAACEKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCC
PVLREDVEQLIKDVSRKLPRGCSDQGETLMAEIDALIEDARASTLGRVLR
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]