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The map label for this gene is aatA [H]

Identifier: 182677081

GI number: 182677081

Start: 87352

End: 88554

Strand: Direct

Name: aatA [H]

Synonym: Bind_0079

Alternate gene names: 182677081

Gene position: 87352-88554 (Clockwise)

Preceding gene: 182677079

Following gene: 182677085

Centisome position: 2.09

GC content: 58.52

Gene sequence:

>1203_bases
ATGTCCTTCATTGCCGATGCCCTGTTGCGTGTAAAACCTTCCGCCACGATCATGGTGACGCAAAAGGCGCGCGATCTTCG
GAATGCGGGACGCGACGTCATCTCGCTGTCGGTCGGCGAGCCGGATTTCGACACGCCCGACAATATCAAGCAGGCGGCGA
TCAAGGCGATCGAGCGGGGCGATACCAAATATACGCCGGTCGCCGGCATCGTGCCCCTGCGCGAGGCCATCGTTCAAAAA
TTCAAGCGCGAGAATCATCTCGACTACAAGCCATCGCAGACCATTGTCGCAACGGGCGGCAAGCACATTCTGTTCAATGC
CTTTCTCGCCACCGTCAATCCGGGCGATGAAGTGATCATTCCGGCTCCTTTCTGGGTCAGCTATCCCGATATGGTGGCGA
TTGCCGGTGGCACGCCGGTCATTGTCGAGACACGGATCGAACAGGGGTTCAAATTGCAGCCCGAGGCGCTTGAGCGCGCG
ATCACGCCCAAGACGAAATGGCTGCTTTTGAATTCGCCCTCCAATCCTTCGGGCGCCGCTTATTCGCGCGCGGAAATGAA
GGCCCTGACGGATGTGCTGTTGCGCCATCCCCAGATCTATGTCCTGAGCGACGATATTTACGAGCATCTGATCTATGGCG
ATTTCACTTTCGTGACGCCGGCGGAGGTGGAGCCGGAACTCATCGACCGCACCTTGACGATGAATGGCGTGTCGAAATCC
TATGCGATGACGGGCTGGCGCATCGGCTATGCGGCGGGACCCGAAAAGCTGATCAAGGCCATGGATATGTTGCAAGGTCA
GCAGACTTCAGGAGCCTGTTCCATCGCGCAATGGGCGGCGGTCGAGGCTTTGACAGGGCCGCAGGATTTCATTGCCGAGC
GGCGCAAAATTTTCGAGGAGCGCCGCGATCTCGTCGTCTCTATGGTCAATCAGGCGAAATATCTGCGCTGTGCCACGCCG
GAAGGCGCATTCTATGTCTTTCCCTCCTGCGCCGAGGCGATCGGCAAGCGGACTCCAGACGGCACATTGATCGAAACCGA
TGAGGATTTCGTCTCGGCCTTTCTTGAGACCGAGGGCGTGGCCGTGGTGCAGGGCTCGGCCTTCGGACAGGGACCGAATT
TCCGGATTTCCTATGCCACGGCGACGCCGATTTTGGAGGAAGCCTGCACCAGGCTCCAGCGTTTCTGCGCGAGCCTGGTT
TAA

Upstream 100 bases:

>100_bases
CAACCGGCTCTTCAATCTTTTTCAATTGTCGGCGTGGCGAGAGCCCCGTAAAACAGCTCCTTTCCTGGTTTCTCCTGAAT
TTCCGCCCAGAGATAGAGTC

Downstream 100 bases:

>100_bases
GCCTTGCCTTCAATCAACCAAAGTCACGATTATTGGCGTGTTTTTCCGCTCGTCAGGCCCGTGCGGGAAAGGCGAGGACT
TGGGCCGGTTTTCCAGCGTC

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSFIADALLRVKPSATIMVTQKARDLRNAGRDVISLSVGEPDFDTPDNIKQAAIKAIERGDTKYTPVAGIVPLREAIVQK
FKRENHLDYKPSQTIVATGGKHILFNAFLATVNPGDEVIIPAPFWVSYPDMVAIAGGTPVIVETRIEQGFKLQPEALERA
ITPKTKWLLLNSPSNPSGAAYSRAEMKALTDVLLRHPQIYVLSDDIYEHLIYGDFTFVTPAEVEPELIDRTLTMNGVSKS
YAMTGWRIGYAAGPEKLIKAMDMLQGQQTSGACSIAQWAAVEALTGPQDFIAERRKIFEERRDLVVSMVNQAKYLRCATP
EGAFYVFPSCAEAIGKRTPDGTLIETDEDFVSAFLETEGVAVVQGSAFGQGPNFRISYATATPILEEACTRLQRFCASLV

Sequences:

>Translated_400_residues
MSFIADALLRVKPSATIMVTQKARDLRNAGRDVISLSVGEPDFDTPDNIKQAAIKAIERGDTKYTPVAGIVPLREAIVQK
FKRENHLDYKPSQTIVATGGKHILFNAFLATVNPGDEVIIPAPFWVSYPDMVAIAGGTPVIVETRIEQGFKLQPEALERA
ITPKTKWLLLNSPSNPSGAAYSRAEMKALTDVLLRHPQIYVLSDDIYEHLIYGDFTFVTPAEVEPELIDRTLTMNGVSKS
YAMTGWRIGYAAGPEKLIKAMDMLQGQQTSGACSIAQWAAVEALTGPQDFIAERRKIFEERRDLVVSMVNQAKYLRCATP
EGAFYVFPSCAEAIGKRTPDGTLIETDEDFVSAFLETEGVAVVQGSAFGQGPNFRISYATATPILEEACTRLQRFCASLV
>Mature_399_residues
SFIADALLRVKPSATIMVTQKARDLRNAGRDVISLSVGEPDFDTPDNIKQAAIKAIERGDTKYTPVAGIVPLREAIVQKF
KRENHLDYKPSQTIVATGGKHILFNAFLATVNPGDEVIIPAPFWVSYPDMVAIAGGTPVIVETRIEQGFKLQPEALERAI
TPKTKWLLLNSPSNPSGAAYSRAEMKALTDVLLRHPQIYVLSDDIYEHLIYGDFTFVTPAEVEPELIDRTLTMNGVSKSY
AMTGWRIGYAAGPEKLIKAMDMLQGQQTSGACSIAQWAAVEALTGPQDFIAERRKIFEERRDLVVSMVNQAKYLRCATPE
GAFYVFPSCAEAIGKRTPDGTLIETDEDFVSAFLETEGVAVVQGSAFGQGPNFRISYATATPILEEACTRLQRFCASLV

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=367, Percent_Identity=27.7929155313352, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI169881279, Length=367, Percent_Identity=27.7929155313352, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI56713254, Length=365, Percent_Identity=27.9452054794521, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI56713256, Length=369, Percent_Identity=27.9132791327913, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI4507369, Length=385, Percent_Identity=24.9350649350649, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI169881281, Length=293, Percent_Identity=24.5733788395904, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1788627, Length=393, Percent_Identity=27.735368956743, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786816, Length=379, Percent_Identity=28.4960422163588, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1788722, Length=363, Percent_Identity=29.4765840220386, Blast_Score=126, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17567663, Length=379, Percent_Identity=23.7467018469657, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=330, Percent_Identity=26.969696969697, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=330, Percent_Identity=26.6666666666667, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=252, Percent_Identity=26.984126984127, Blast_Score=111, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6322401, Length=233, Percent_Identity=31.3304721030043, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6320317, Length=250, Percent_Identity=27.6, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573069, Length=364, Percent_Identity=25.8241758241758, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24646114, Length=364, Percent_Identity=25.8241758241758, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI28573067, Length=364, Percent_Identity=25.8241758241758, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI28573065, Length=364, Percent_Identity=25.8241758241758, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI18859735, Length=388, Percent_Identity=24.7422680412371, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI45551451, Length=398, Percent_Identity=26.3819095477387, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24641770, Length=398, Percent_Identity=26.3819095477387, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641760, Length=398, Percent_Identity=26.3819095477387, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641768, Length=398, Percent_Identity=26.3819095477387, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641766, Length=398, Percent_Identity=26.3819095477387, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641764, Length=398, Percent_Identity=26.3819095477387, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43902; Mature: 43771

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFIADALLRVKPSATIMVTQKARDLRNAGRDVISLSVGEPDFDTPDNIKQAAIKAIERG
CCHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCC
DTKYTPVAGIVPLREAIVQKFKRENHLDYKPSQTIVATGGKHILFNAFLATVNPGDEVII
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEEEEECCCCCCEEE
PAPFWVSYPDMVAIAGGTPVIVETRIEQGFKLQPEALERAITPKTKWLLLNSPSNPSGAA
CCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCH
YSRAEMKALTDVLLRHPQIYVLSDDIYEHLIYGDFTFVTPAEVEPELIDRTLTMNGVSKS
HHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHCCEEEECCCCCCHHHHHHHHEECCCCCH
YAMTGWRIGYAAGPEKLIKAMDMLQGQQTSGACSIAQWAAVEALTGPQDFIAERRKIFEE
HEECCEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
RRDLVVSMVNQAKYLRCATPEGAFYVFPSCAEAIGKRTPDGTLIETDEDFVSAFLETEGV
HHHHHHHHHHHHHEEEEECCCCCEEECCHHHHHHCCCCCCCCEEECCHHHHHHHHHCCCE
AVVQGSAFGQGPNFRISYATATPILEEACTRLQRFCASLV
EEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SFIADALLRVKPSATIMVTQKARDLRNAGRDVISLSVGEPDFDTPDNIKQAAIKAIERG
CHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCC
DTKYTPVAGIVPLREAIVQKFKRENHLDYKPSQTIVATGGKHILFNAFLATVNPGDEVII
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEEEEECCCCCCEEE
PAPFWVSYPDMVAIAGGTPVIVETRIEQGFKLQPEALERAITPKTKWLLLNSPSNPSGAA
CCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCH
YSRAEMKALTDVLLRHPQIYVLSDDIYEHLIYGDFTFVTPAEVEPELIDRTLTMNGVSKS
HHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHCCEEEECCCCCCHHHHHHHHEECCCCCH
YAMTGWRIGYAAGPEKLIKAMDMLQGQQTSGACSIAQWAAVEALTGPQDFIAERRKIFEE
HEECCEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
RRDLVVSMVNQAKYLRCATPEGAFYVFPSCAEAIGKRTPDGTLIETDEDFVSAFLETEGV
HHHHHHHHHHHHHEEEEECCCCCEEECCHHHHHHCCCCCCCCEEECCHHHHHHHHHCCCE
AVVQGSAFGQGPNFRISYATATPILEEACTRLQRFCASLV
EEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]